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Next generation APOBEC3 inhibitors: optimally designed for potency and nuclease stability Hedger, Adam K.; Myint, Wazo; Lee, Jeong Min; Loustaunau, Diego Suchenski; Balachandran, Vanivilasini; Shaqra, Ala M.; Kurt Yilmaz, Nese; Watts, Jonathan K.; Matsuo, Hiroshi; Schiffer, Celia A. Share Save
Preventing acute neurotoxicity of CNS therapeutic oligonucleotides with the addition of Ca2+and Mg2+in the formulation Miller, Rachael; Paquette, Joseph; Barker, Alexandra; Sapp, Ellen; McHugh, Nicholas; Bramato, Brianna; Yamada, Nozomi; Alterman, Julia; Echeveria, Dimas; Yamada, Ken; Watts, Jonathan; Anaclet, Christelle; DiFiglia, Marian; Khvorova, Anastasia; Aronin, Neil Share Save
Increasing intracellular dNTP levels improves prime editing efficiency Liu, Pengpeng; Ponnienselvan, Karthikeyan; Nyalile, Thomas; Oikemus, Sarah; Joynt, Anya T.; Iyer, Sukanya; Kelly, Karen; Guo, Dongsheng; Kyawe, Pyae P.; Vanderleeden, Emma; Redick, Sambra D.; Huang, Lei; Chen, Zexiang; Lee, Jeong Min; Schiffer, Celia A.; Harlan, David M.; Wang, Jennifer P.; Emerson Jr, Charles P.; Lawson, Nathan D.; Watts, Jonathan K.; Sontheimer, Erik J.; Luban, Jeremy; Wolfe, Scot A. Share Save
CASCADES, a novel SOX2 super-enhancer-associated long noncoding RNA, regulates cancer stem cell specification and differentiation in glioblastoma Shahzad, Uswa; Nikolopoulos, Marina; Li, Christopher; Johnston, Michael; Wang, Jenny J.; Sabha, Nesrin; Varn, Frederick S.; Riemenschneider, Alexandra; Krumholtz, Stacey; Krishnamurthy, Pranathi Meda; Smith, Christian A.; Karamchandani, Jason; Watts, Jonathan K.; Verhaak, Roel G. W.; Gallo, Marco; Rutka, James T.; Das, Sunit Share Save
Quantifying the activity profile of ASO and siRNA conjugates in glioblastoma xenograft tumors in vivo Sarli, Samantha L.; Fakih, Hassan H.; Kelly, Karen; Devi, Gitali; Rembetsy-Brown, Julia M.; McEachern, Holly R.; Ferguson, Chantal M.; Echeverria, Dimas; Lee, Jonathan; Sousa, Jacquelyn; Sleiman, Hanadi F.; Khvorova, Anastasia; Watts, Jonathan K. Share Save
EZH2 inhibition reactivates epigenetically silenced FMR1 and normalizes molecular and electrophysiological abnormalities in fragile X syndrome neurons Fang, Minggang; Deibler, Sara K.; Krishnamurthy, Pranathi Meda; Wang, Feng; Rodriguez, Paola; Banday, Shahid; Virbasius, Ching-Man; Sena-Esteves, Miguel; Watts, Jonathan K.; Green, Michael R. Share Save
Domain-inlaid Nme2Cas9 adenine base editors with improved activity and targeting scope Bamidele, Nathan; Zhang, Han; Dong, Xiaolong; Cheng, Haoyang; Gaston, Nicholas; Feinzig, Hailey; Cao, Hanbing; Kelly, Karen; Watts, Jonathan K.; Xie, Jun; Gao, Guangping; Sontheimer, Erik J. Share Save
A combinatorial approach for achieving CNS-selective RNAi Ferguson, Chantal M.; Godinho, Bruno M. D. C.; Echeverria, Dimas; Hassler, Matthew; Vangjeli, Lorenc; Sousa, Jacquelyn; Mchugh, Nicholas; Alterman, Julia; Hariharan, Vignesh; Krishnamurthy, Pranathi Meda; Watts, Jonathan; Rogaev, Eveny; Khvorova, Anastasia Share Save
A Fluorescent Reporter Mouse for In Vivo Assessment of Genome Editing with Diverse Cas Nucleases and Prime Editors Chen, Zexiang; Kwan, Suet-Yan; Mir, Aamir; Hazeltine, Max; Shin, Minwook; Liang, Shun-Qing; Chan, Io Long; Kelly, Karen; Ghanta, Krishna S.; Gaston, Nicholas; Cao, Yueying; Xie, Jun; Gao, Guangping; Xue, Wen; Sontheimer, Erik J.; Watts, Jonathan K. Share Save
Dendritic amphiphilic siRNA: Selective albumin binding, in vivo efficacy, and low toxicity Fakih, Hassan H.; Tang, Qi; Summers, Ashley; Shin, Minwook; Buchwald, Julianna E.; Gagnon, Rosemary; Hariharan, Vignesh N.; Echeverria, Dimas; Cooper, David A.; Watts, Jonathan K.; Khvorova, Anastasia; Sleiman, Hanadi F. Share Save
Self-delivering, chemically modified CRISPR RNAs for AAV co-delivery and genome editing in vivo Zhang, Han; Kelly, Karen; Lee, Jonathan; Echeverria, Dimas; Cooper, David; Panwala, Rebecca; Amrani, Nadia; Chen, Zexiang; Gaston, Nicholas; Wagh, Atish; Newby, Gregory A.; Xie, Jun; Liu, David R.; Gao, Guangping; Wolfe, Scot A.; Khvorova, Anastasia; Watts, Jonathan K.; Sontheimer, Erik J. Share Save
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Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection Hariharan, Vignesh N.; Shin, Minwook; Chang, Ching-Wen; O'Reilly, Daniel; Biscans, Annabelle; Yamada, Ken; Guo, Zhiru; Somasundaran, Mohan; Tang, Qi; Monopoli, Kathryn; Krishnamurthy, Pranathi Meda; Devi, Gitali; McHugh, Nicholas; Cooper, David A.; Echeverria, Dimas; Cruz, John; Chan, Io Long; Liu, Ping; Lim, Sun-Young; McConnell, Jill; Singh, Satya Prakash; Hildebrand, Samuel; Sousa, Jacquelyn; Davis, Sarah M.; Kennedy, Zachary; Ferguson, Chantal; Godinho, Bruno M. D. C.; Thillier, Yann; Caiazzi, Jillian; Ly, Socheata; Muhuri, Manish; Kelly, Karen; Humphries, Fiachra; Cousineau, Alyssa; Parsi, Krishna Mohan; Li, Qi; Wang, Yang; Maehr, Rene; Gao, Guangping; Korkin, Dmitry; McDougall, William M.; Finberg, Robert W.; Fitzgerald, Katherine A.; Wang, Jennifer P.; Watts, Jonathan K.; Khvorova, Anastasia Share Save
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