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SaveShare Save Share Save Share Save Share Save The novel BCL-2/BCL-XL inhibitor APG-1252-mediated cleavage of GSDME enhances the antitumor efficacy of HER2-targeted therapy in HER2-positive gastric cancer
Luo, Qiu-yun; Yang, Jing; Di, Tian; Xia, Zeng-fei; Zhang, Lin; Pan, Wen-tao; Shi, Shan; Yang, Li-qiong; Sun, Jian; Qiu, Miao-zhen; Yang, Da-jun Share Save YTHDF2 upregulation and subcellular localization dictate CD8 T cell polyfunctionality in anti-tumor immunityZhang, Haiyan; Luo, Xiaojing; Yang, Wei; Wu, Zhiying; Zhao, Zhicong; Pei, Xin; Zhang, Xue; Chen, Chonghao; Lei, Josh Haipeng; Shi, Qingxia; Zhao, Qi; Chen, Yanxing; Wu, Wenwei; Zeng, Zhaolei; Ju, Huai-Qiang; Qiu, Miaozhen; Liu, Jun; Shen, Bin; Chen, Minshan; Chen, Jianjun; Deng, Chu-Xia; Xu, Rui-Hua; Hou, Jiajie Share Save APG-1252 combined with Cabozantinib inhibits hepatocellular carcinoma by suppressing MEK/ERK and CREB/Bcl-xl pathwaysDi, Tian; Luo, Qiu-yun; Song, Jiang-tao; Yan, Xiang-lei; Zhang, Lin; Pan, Wen-tao; Guo, Yu; Lu, Fei-teng; Sun, Yu-ting; Xia, Zeng-fei; Yang, Li-qiong; Qiu, Miao-zhen; Yang, Da-jun; Sun, Jian Share Save Tislelizumab plus chemotherapy versus placebo plus chemotherapy as first line treatment for advanced gastric or gastro-oesophageal junction adenocarcinoma: RATIONALE-305 randomised, double blind, phase 3 trialQiu, Miao-Zhen; Oh, Do-Youn; Kato, Ken; Arkenau, Tobias; Tabernero, Josep; Correa, Marcia Cruz; Zimina, Anastasia, V; Bai, Yuxian; Shi, Jianhua; Lee, Keun-Wook; Wang, Jufeng; Poddubskaya, Elena; Pan, Hongming; Rha, Sun Young; Zhang, Ruixing; Hirano, Hidekazu; Spigel, David; Yamaguchi, Kensei; Chao, Yee; Wyrwicz, Lucjan; Disel, Umut; Cid, Roberto Pazo; Fornaro, Lorenzo; Evesque, Ludovic; Wang, Hongwei; Xu, Yaling; Li, Jiang; Sheng, Tao; Yang, Silu; Li, Liyun; Moehler, Markus; Xu, Rui-Hua Share Save Synergistic effects of Smac mimetic APG-1387 with anti-PD-1 antibody are attributed to increased CD3+NK1.1+cell recruitment secondary to induction of cytokines from tumor cellsPan, Wentao; Luo, Qiuyun; Liang, Eric; Shi, Mude; Sun, Jian; Shen, Huimin; Lu, Zhenhai; Zhang, Lin; Yan, Xianglei; Yuan, Luping; Zhou, Suna; Yi, Hanjie; Zhai, Yifan; Qiu, Miao-zhen; Yang, Dajun Share Save Combined anti-PD-1, HDAC inhibitor and anti-VEGF for MSS/pMMR colorectal cancer: a randomized phase 2 trialWang, Feng; Jin, Ying; Wang, Min; Luo, Hui-Yan; Fang, Wei-Jia; Wang, Ying-Nan; Chen, Yan-Xing; Huang, Run-Jie; Guan, Wen-Long; Li, Ji-Bin; Li, Yu-Hong; Wang, Feng-Hua; Hu, Xiao-Hua; Zhang, Yan-Qiao; Qiu, Miao-Zhen; Liu, Lu-Lu; Wang, Zi-Xian; Ren, Chao; Wang, De-Shen; Zhang, Dong-Sheng; Wang, Zhi-Qiang; Liao, Wen-Ting; Tian, Lin; Zhao, Qi; Xu, Rui-Hua Share Save The Chinese Society of Clinical Oncology (CSCO): Clinical guidelines for the diagnosis and treatment of gastric cancer, 2023Wang, Feng-Hua; Zhang, Xiao-Tian; Tang, Lei; Wu, Qi; Cai, Mu-Yan; Li, Yuan-Fang; Qu, Xiu-Juan; Qiu, Hong; Zhang, Yu-Jing; Ying, Jie-Er; Zhang, Jun; Sun, Ling-Yu; Lin, Rong-Bo; Wang, Chang; Liu, Hao; Qiu, Miao-Zhen; Guan, Wen-Long; Rao, Sheng-Xiang; Ji, Jia-Fu; Xin, Yan; Sheng, Wei-Qi; Xu, Hui-Mian; Zhou, Zhi-Wei; Zhou, Ai-Ping; Jin, Jing; Yuan, Xiang-Lin; Bi, Feng; Liu, Tian-Shu; Liang, Han; Zhang, Yan-Qiao; Li, Guo-Xin; Liang, Jun; Liu, Bao-Rui; Shen, Lin; Li, Jin; Xu, Rui-Hua Share Save SHR-1701 in combination with BP102 and XELOX as first-line (1L) treatment for patients (pts) with unresectable metastatic colorectal cancer (mCRC): Data from a phase II/III studyXu, R-H.; Qiu, M.; Bai, Y.; Wang, J.; Gu, K.; Yang, M.; He, Y.; Yi, C.; Jin, Y.; Liu, B.; Wang, F.; Huang, C.; Jiang, Y. Share Save A phase II clinical trial of sintilimab plus chidamide combined with or without bevacizumab in patients with MSS/pMMR metastatic colorectal cancerWang, F.; Jin, Y.; Luo, H-Y.; Guan, W-L.; Li, Y.; Wang, F.; Qiu, M.; Liu, L-L.; Hu, X.; Zhang, Y.; Fang, W.; Wang, Z-X.; Ren, C.; Wang, D.; Xu, R-H. Share Save Precise microdissection of gastric mixed adeno-neuroendocrine carcinoma dissects its genomic landscape and evolutionary clonal originsQiu, Miao-Zhen; Chen, Qingjian; Zheng, Dan-Yang; Zhao, Qi; Wu, Qi-Nian; Zhou, Zhi-Wei; Yang, Li-Qiong; Luo, Qiu-Yun; Sun, Yu-Ting; Lai, Ming-Yu; Yuan, Sha-Sha; Wang, Feng-Hua; Luo, Hui-Yan; Wang, Feng; Li, Yu-Hong; Zhang, Hui-Zhong; Xu, Rui-Hua Share Save Caspase-3 mediated cleavage of GSDME enhances the antitumor efficacy of HER2-targeted therapy in HER2-positive gastric cancerLuo, Qiuyun; Xia, Zengfei; Yang, Jing; Pan, Wentao; Luo, Fan; Cao, Jiaxin; Sun, Yuting; Yang, Liqiong; Zhang, Lin; Qiu, Miaozhen; Yang, Dajun Share Save RETRACTION: Suppression of fumarate hydratase activity increases the efficacy of cisplatin-mediated chemotherapy in gastric cancer (Retraction of 10.1038/S41419-019-1652-8, 2019)Yu, Hong-En; Wang, Feng; Yu, Fang; Zeng, Zhao-Lei; Wang, Yun; Lu, Yun-Xin; Jin, Ying; Wang, De-Shen; Qiu, Miao-Zhen; Pu, Heng-Ying; Kang, Tie-Bang; Xie, Dan; Ju, Huai-Qiang; Xu, Rui-Hua; Luo, Hui-Yan Share Save First-in-human phase Ia study of the PI3Kα inhibitor CYH33 in patients with solid tumorsWei, Xiao-Li; Liu, Fu-Rong; Liu, Ji-Hong; Zhao, Hong-Yun; Zhang, Yang; Wang, Zhi-Qiang; Qiu, Miao-Zhen; Xu, Fei; Yu, Qiu-Qiong; Du, Yi-Wu; Shi, Yan-Xia; Wang, De-Sheng; Wang, Feng-Hua; Xu, Rui-Hua Share Save Phase 1 multicenter, dose-expansion study of ARX788 as monotherapy in HER2-positive advanced gastric and gastroesophageal junction adenocarcinomaZhang, Yang; Qiu, Miao-Zhen; Wang, Ju-Feng; Zhang, Yan-Qiao; Shen, Ao; Yuan, Xiang-Lin; Zhang, Tao; Wei, Xiao-Li; Zhao, Hong-Yun; Wang, De-Shen; Zhao, Qi; Xiong, Gao-Zhun; Ji, Yan-Ping; Liang, Xue-Jun; Xia, Gang; Xu, Rui-Hua Share Save 
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