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Thienopyrimidinone Derivatives as a GluN2B/C/D Biased, Positive Allosteric Modulator of the N-Methyl-d-Aspartate Receptor Fritzemeier, Russell G.; Akins, Nicholas S.; Arcoria, Paul J.; Paladugu, Srinu; Ullman, Elijah Z.; Allen, James; Sheikh, Rehan; Nocilla, Kelsey A.; McDaniels, Ellington D.; Coleman, Emanuel M.; Antonoudiou, Pantelis; D'Erasmo, Michael P.; Bartsch, Perry; Sharma, Savita K.; Maguire, Jamie; Traynelis, Stephen F.; Liotta, Dennis C. Share Save
Ligand distances as key predictors of pathogenicity and function in NMDA receptors Montanucci, Ludovica; Bruenger, Tobias; Bhattarai, Nisha; Bosselmann, Christian M.; Kim, Sukhan; Allen, James P.; Zhang, Jing; Kloeckner, Chiara; Krey, Ilona; Fariselli, Piero; May, Patrick; Lemke, Johannes R.; Myers, Scott J.; Yuan, Hongjie; Traynelis, Stephen F.; Lal, Dennis Share Save
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De novo GRIN variants in M3 helix associated with neurological disorders control channel gating of NMDA receptor Xu, Yuchen; Song, Rui; Perszyk, Riley E.; Chen, Wenjuan; Kim, Sukhan; Park, Kristen L.; Allen, James P.; Nocilla, Kelsey A.; Zhang, Jing; Xiangwei, Wenshu; Tankovic, Anel; McDaniels, Ellington D.; Sheikh, Rehan; Mizu, Ruth K.; Karamchandani, Manish M.; Hu, Chun; Kusumoto, Hirofumi; Pecha, Joseph; Cappuccio, Gerarda; Gaitanis, John; Sullivan, Jennifer; Shashi, Vandana; Petrovski, Slave; Jauss, Robin-Tobias; Lee, Hyun Kyung; Bozarth, Xiuhua; Lynch, David R.; Helbig, Ingo; Pierson, Tyler Mark; Boerkoel, Cornelius F.; Myers, Scott J.; Lemke, Johannes R.; Benke, Timothy A.; Yuan, Hongjie; Traynelis, Stephen F. Share Save
Clinical features, functional consequences, and rescue pharmacology of missense GRID1 and GRID2 human variants Allen, James P.; Garber, Kathryn B.; Perszyk, Riley; Khayat, Cara T.; Kell, Steven A.; Kaneko, Maki; Quindipan, Catherine; Saitta, Sulagna; Ladda, Roger L.; Hewson, Stacy; Inbar-Feigenberg, Michal; Prasad, Chitra; Prasad, Asuri N.; Olewiler, Leah; Mu, Weiyu; Rosenthal, Liana S.; Scala, Marcello; Striano, Pasquale; Zara, Federico; McCullock, Tyler W.; Jauss, Robin-Tobias; Lemke, Johannes R.; MacLean, David M.; Zhu, Cheng; Yuan, Hongjie; Myers, Scott J.; Traynelis, Stephen F. Share Save
Development of a Dihydroquinoline-Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of the N-Methyl-d-aspartate Receptor D'Erasmo, Michael P.; Akins, Nicholas S.; Ma, Peipei; Jing, Yao; Swanger, Sharon A.; Sharma, Savita K.; Bartsch, Perry W.; Menaldino, David S.; Arcoria, Paul J.; Bui, Thi-Thien; Pons-Bennaceur, Alexandre; Le, Phuong; Allen, James P.; Ullman, Elijah Z.; Nocilla, Kelsey A.; Zhang, Jing; Perszyk, Riley E.; Kim, Sukhan; Acker, Timothy M.; Taz, Azmain; Burton, Samantha L.; Coe, Kevin; Fritzemeier, Russell G.; Burnashev, Nail; Yuan, Hongjie; Liotta, Dennis C.; Traynelis, Stephen F. Share Save
Classification of missense variants in the N-methyl-d-aspartate receptor GRIN gene family as gain- or loss-of-function Myers, Scott J.; Yuan, Hongjie; Perszyk, Riley E.; Zhang, Jing; Kim, Sukhan; Nocilla, Kelsey A.; Allen, James P.; Bain, Jennifer M.; Lemke, Johannes R.; Lal, Dennis; Benke, Timothy A.; Traynelis, Stephen F. Share Save
Overlapping cortical malformations in patients with pathogenic variants in GRIN1 and GRIN2B Brock, Stefanie; Laquerriere, Annie; Marguet, Florent; Myers, Scott J.; Hongjie, Yuan; Baralle, Diana; Vanderhasselt, Tim; Stouffs, Katrien; Keymolen, Kathelijn; Kim, Sukhan; Allen, James; Shaulsky, Gil; Chelly, Jamel; Marcorelle, Pascale; Aziza, Jacqueline; Villard, Laurent; Sacaze, Elise; de Wit, Marie C. Y.; Wilke, Martina; Mancini, Grazia Maria Simonetta; Hehr, Ute; Lim, Derek; Mansour, Sahar; Traynelis, Stephen F.; Beneteau, Claire; Denis-Musquer, Marie; Jansen, Anna C.; Fry, Andrew E.; Bahi-Buisson, Nadia Share Save
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