Edward G. D. Tuddenham - Publications, H-index & Citations

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Edward G. D. Tuddenham

university college london cancer institute

71H-index

394Paper Count

2.1WCitation Count

Published Papers 62

Publication Date

Alternative AAV gene therapy for hemophilia A using expression of Bi8, a novel single-chain FVIII-mimetic antibody

Blood

IF23.1

2025-09-24

PREAI

Vincent Muczynski; Olivier D. Christophe; Lewis Tanner; Charlotte Vayssiere; Alice Guérin; Caterina Casari; Jenny McIntosh; Doyoung Lee; Gavin Ling; Satyen Gohil; Peter J. Lenting; Edward Tuddenham; Amit C. Nathwani

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Mathematical models of coagulation-are we there yet?

JOURNAL OF THROMBOSIS AND HAEMOSTASIS

IF5

2024-06-01

OAAI

Owen, Matt J.; Wright, Joy R.; Tuddenham, Edward G. D.; King, John R.; Goodall, Alison H.; Dunster, Joanne L.

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Phase 1-2 Trial of AAVS3 Gene Therapy in Patients with Hemophilia B

NEW ENGLAND JOURNAL OF MEDICINE

IF78.5

2022-07-21

OAAI

Chowdary, Pratima; Shapiro, Susan; Makris, Mike; Evans, Gillian; Boyce, Sara; Talks, Kate; Dolan, Gerard; Reiss, Ulrike; Phillips, Mark; Riddell, Anne; Peralta, Maria R.; Quaye, Michelle; Patch, David W.; Tuddenham, Edward; Dane, Allison; Watissee, Marie; Long, Alison; Nathwani, Amit

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Global coagulation assays in hemophilia A: A comparison to conventional assays

RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS

IF3.4

2020-02-01

OAAI

Aghighi, Saman; Riddell, Anne; Lee, Christine A.; Brown, Simon A.; Tuddenham, Edward; Chowdary, Pratima

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Interaction Between the a3 Region of Factor VIII and the TIL'E' Domains of the von Willebrand Factor

BIOPHYSICAL JOURNAL

IF3.1

2019-08-01

OAAI

Dagil, Lisbeth; Troelsen, Kathrin S.; Bolt, Gert; Thim, Lars; Wu, Bo; Zhao, Xin; Tuddenham, Edward G. D.; Nielsen, Thomas E.; Tanner, David A.; Faber, Johan H.; Breinholt, Jens; Rasmussen, Jakob E.; Hansen, D. Flemming

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Pharmacodynamic resistance to warfarin associated with a Val66Met substitution in vitamin K epoxide reductase complex subunit I

THROMBOSIS AND HAEMOSTASIS

IF4.3

2017-12-14

127

OAAI

Harrington, DJ; Underwood, S; Morse, C; Shearer, MJ; Tuddenham, EGD; Mumford, AD

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Factor VII and cardiovascular risk

THROMBOSIS AND HAEMOSTASIS

IF4.3

2017-12-11

PREAI

Tuddenham, EGD

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Molecular evolution of the vertebrate blood coagulation network

THROMBOSIS AND HAEMOSTASIS

IF4.3

2017-12-09

PREAI

Davidson, CJ; Hirt, RP; Lal, K; Snell, P; Elgar, G; Tuddenham, EGD; McVey, JH

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Ways to bypass a blocked tenase complex

THROMBOSIS AND HAEMOSTASIS

IF4.3

2017-11-28

PREAI

Tuddenham, EGD

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Monitoring low dose recombinant factor VIIa therapy in patients with severe factor XI deficiency undergoing surgery

THROMBOSIS AND HAEMOSTASIS

IF4.3

2017-11-24

PREAI

Riddell, Anne; Abdul-Kadir, Rezan; Pollard, Debra; Tuddenham, Edward; Gomez, Keith

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Structural analysis of eight novel and 112 previously reported missense mutations in the interactive FXI mutation database reveals new insight on FXI deficiency

THROMBOSIS AND HAEMOSTASIS

IF4.3

2017-11-22

PREAI

Saunders, Rebecca E.; Shiltagh, Nuha; Gomez, Keith; Mellars, Gillian; Cooper, Carolyn; Perry, David J.; Tuddenham, Edward G.; Perkins, Stephen J.

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Platelets are a safe way to deliver factor VIII. After 13 years of preclinical research it is now time for a clinical trial

JOURNAL OF THROMBOSIS AND HAEMOSTASIS

IF5

2017-01-01

OAAI

Tuddenham, E. G.

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The impact of sport on health status, psychological well-being and physical performance of adults with haemophilia

HAEMOPHILIA

IF3

2016-05-24

PREAI

von Mackensen, S.; Harrington, C.; Tuddenham, E.; Littley, A.; Will, A.; Fareh, M.; Hay, C. R. M.; Khair, K.

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First steps in the standardization of immunoglobulin IgG myeloperoxidase-anti-neutrophil cytoplasmic antibody measurements

CLINICAL AND EXPERIMENTAL IMMUNOLOGY

IF3.8

2015-11-18

OAAI

Hutu, D. P.; Tuddenham, E.; Monogioudi, E.; Meroni, P.; Schimmel, H.; Sheldon, J.; Zegers, I.

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Novel, human cell line-derived recombinant factor VIII (human-cl rhFVIII; Nuwiq®) in adults with severe haemophilia A: efficacy and safety

HAEMOPHILIA

IF3

2015-08-28

OAAI

Lissitchkov, T.; Hampton, K.; von Depka, M.; Hay, C.; Rangarajan, S.; Tuddenham, E.; Holstein, K.; Huth-Kuehne, A.; Pabinger, I.; Knaub, S.; Bichler, J.; Oldenburg, J.

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Long-Term Safety and Efficacy of Factor IX Gene Therapy in Hemophilia B

NEW ENGLAND JOURNAL OF MEDICINE

IF78.5

2014-11-20

1.1K

OAAI

Nathwani, A. C.; Reiss, U. M.; Tuddenham, E. G. D.; Rosales, C.; Chowdary, P.; McIntosh, J.; Della Peruta, M.; Lheriteau, E.; Patel, N.; Raj, D.; Riddell, A.; Pie, J.; Rangarajan, S.; Bevan, D.; Recht, M.; Shen, Y. -M.; Halka, K. G.; Basner-Tschakarjan, E.; Mingozzi, F.; High, K. A.; Allay, J.; Kay, M. A.; Ng, C. Y. C.; Zhou, J.; Cancio, M.; Morton, C. L.; Gray, J. T.; Srivastava, D.; Nienhuis, A. W.; Davidoff, A. M.

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Far away and long ago

JOURNAL OF THROMBOSIS AND HAEMOSTASIS

IF5

2014-01-01

OAAI

Tuddenham, E.

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An interactive mutation database for human coagulation factor IX provides novel insights into the phenotypes and genetics of hemophilia B

JOURNAL OF THROMBOSIS AND HAEMOSTASIS

IF5

2013-07-01