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Effective therapeutic targeting of CTNNB1-mutant hepatoblastoma with WNTinib Balaseviciute, Ugne; Huguet-Pradell, Julia; Abril-Fornaguera, Jordi; Gris-Oliver, Albert; Rialdi, Alex; Fernandez-Martinez, Elisa; Montironi, Carla; Del Pozo, Vanessa; Houghton, Peter; Zanatto, Laura; Mesropian, Agavni; Keraite, Ieva; Thung, Swan; Armengol, Carolina; Sancho-Bru, Pau; Guccione, Ernesto; Pinyol, Roser; Llovet, Josep M. Share Save
Differential splice isoforms of mouse CDK2 play functionally redundant roles during mitotic and meiotic division Palmer, Nathan; Kalem-Yapar, Nisan Ece; Hulten, Hanna; Keles, Umur; Talib, S. Zakiah A.; Ow, Jin Rong; Tabaglio, Tommaso; Goh, Christine M. F.; Zhao, Li Na; Guccione, Ernesto; Liu, Kui; Kaldis, Philipp Share Save
Discovery of a Potent and Selective Protein Arginine Methyltransferase 5 (PRMT5) PROTAC Degrader Zhong, Yue; Kim, Huensuk; Qian, Chao; Xie, Ling; Chen, Xian; Xiong, Yan; Hu, Jacqueline; Chen, Matthew; Guccione, Ernesto; Shen, Yudao Share Save
Unveiling sequence-agnostic mixed-chemical modification patterns for splice-switching oligonucleotides using the NATURA platform Tabaglio, Tommaso; Agarwal, Taniya; Cher, Wei Yuan; Ow, Jin Rong; Chew, Ah Keng; Sun, Priscila Yun Qian; Gurrampati, Raja Sekhar Reddy; Lu, Hongfang; Naidu, Praveena; Ng, Hong Kai; Le Guezennec, Xavier; Ng, Shi Yan; Lakshmanan, Manikandan; Guccione, Ernesto; Wee, Keng Boon Share Save
Maternal PRDM10 activates essential genes for oocyte-to-embryo transition Seah, Michelle K. Y.; Han, Brenda Y.; Huang, Yan; Rasmussen, Louise J. H.; Staubli, Andrina J.; Bello-Rodriguez, Judith; Chan, Andrew Chi-Ho; Gasnier, Maxime; Wollmann, Heike; Guccione, Ernesto; Messerschmidt, Daniel M. Share Save
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Steering research on mRNA splicing in cancer towards clinical translation Anczukow, Olga; Allain, Frederic H. -T.; Angarola, Brittany L.; Black, Douglas L.; Brooks, Angela N.; Cheng, Chonghui; Conesa, Ana; Crosse, Edie I.; Eyras, Eduardo; Guccione, Ernesto; Lu, Sydney X.; Neugebauer, Karla M.; Sehgal, Priyanka; Song, Xiao; Tothova, Zuzana; Valcarcel, Juan; Weeks, Kevin M.; Yeo, Gene W.; Thomas-Tikhonenko, Andrei Share Save
E7386 enhances both lenvatinib and anti-PD1 antitumor activity in HCC Mesropian Badalian, A.; Gris-Oliver, A.; Abril-Fornaguera, J.; Pique-Gili, M.; Torres-Marcen, M.; Camell-Raventos, D.; Peix, J.; Fernandez-Martinez, E.; Balaseviciute, U.; Huguet-Pradell, J.; Keraite, I.; Esteban-Fabro, R.; Pinyol, R.; Barcena-Varela, M.; Lindblad, K. E.; Lujambio, A.; Guccione, E.; Thung, S. N.; Sia, D.; Llovet, J. M. Share Save
Efficacy of WNTinib, a novel selective therapeutic for CTNNB1-mutant tumors, in preclinical models of hepatoblastoma Balaseviciute, U.; Abril-Fornaguera, J.; Huguet-Pradell, J.; Fernandez-Martinez, E.; Gris-Oliver, A.; Rialdi, A.; Mesropian, A.; Ulukaya, G.; Hasson, D.; Keraite, I.; Pinyol, R.; Thung, S. N.; Guccione, E.; Llovet, J. Share Save
A PRMT5-ZNF326 axis mediates innate immune activation upon replication stress Hoang, Phuong Mai; Torre, Denis; Jaynes, Patrick; Ho, Jessica; Mohammed, Kevin; Alvstad, Erik; Lam, Wan Yee; Khanchandani, Vartika; Lee, Jie Min; Toh, Chin Min Clarissa; Lee, Rui Xue; Anbuselvan, Akshaya; Lee, Sukchan; Sebra, Robert P.; Walsh, Martin J.; Marazzi, Ivan; Kappei, Dennis; Guccione, Ernesto; Jeyasekharan, Anand D. Share Save
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SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion Leuzzi, Giuseppe; Vasciaveo, Alessandro; Taglialatela, Angelo; Chen, Xiao; Firestone, Tessa M.; Hickman, Allison R.; Mao, Wendy; Thakar, Tanay; Vaitsiankova, Alina; Huang, Jen-Wei; Cuella-Martin, Raquel; Hayward, Samuel B.; Kesner, Jordan S.; Ghasemzadeh, Ali; Nambiar, Tarun S.; Ho, Patricia; Rialdi, Alexander; Hebrard, Maxime; Li, Yinglu; Gao, Jinmei; Gopinath, Saarang; Adeleke, Oluwatobi A.; Venters, Bryan; Drake, Charles G.; Baer, Richard; Izar, Benjamin; Guccione, Ernesto; Keogh, Michael-Christopher; Guerois, Raphael; Sun, Lu; Lu, Chao; Califano, Andrea; Ciccia, Alberto Share Save
RBFOX2 deregulation promotes pancreatic cancer progression and metastasis through alternative splicing Maurin, Michelle; Ranjouri, Mohammadreza; Megino-Luque, Cristina; Newberg, Justin Y.; Du, Dongliang; Martin, Katelyn; Miner III, Robert E.; Prater, Mollie S.; Wee, Dave Keng Boon; Centeno, Barbara; Pruett-Miller, Shondra M.; Stewart, Paul; Fleming, Jason B.; Yu, Xiaoqing; Bravo-Cordero, Jose Javier; Guccione, Ernesto; Black, Michael A.; Mann, Karen M. Share Save
MYOD-SKP2 axis boosts tumorigenesis in fusion negative rhabdomyosarcoma by preventing differentiation through p57Kip2 targeting Pomella, Silvia; Cassandri, Matteo; D'Archivio, Lucrezia; Porrazzo, Antonella; Cossetti, Cristina; Phelps, Doris; Perrone, Clara; Pezzella, Michele; Cardinale, Antonella; Wachtel, Marco; Aloisi, Sara; Milewski, David; Colletti, Marta; Sreenivas, Prethish; Walters, Zoe S.; Barillari, Giovanni; Di Giannatale, Angela; Milano, Giuseppe Maria; De Stefanis, Cristiano; Alaggio, Rita; Rodriguez-Rodriguez, Sonia; Carlesso, Nadia; Vakoc, Christopher R.; Velardi, Enrico; Schafer, Beat W.; Guccione, Ernesto; Gatz, Susanne A.; Wasti, Ajla; Yohe, Marielle; Ignatius, Myron; Quintarelli, Concetta; Shipley, Janet; Miele, Lucio; Khan, Javed; Houghton, Peter J.; Marampon, Francesco; Gryder, Berkley E.; De Angelis, Biagio; Locatelli, Franco; Rota, Rossella Share Save
Nuclear RNA catabolism controls endogenous retroviruses, gene expression asymmetry, and dedifferentiation Torre, Denis; Fstkchyan, Yesai S.; Ho, Jessica Sook Yuin; Cheon, Youngseo; Patel, Roosheel S.; Degrace, Emma J.; Mzoughi, Slim; Schwarz, Megan; Mohammed, Kevin; Seo, Ji-Seon; Romero-Bueno, Raquel; Demircioglu, Deniz; Hasson, Dan; Tang, Weijing; Mahajani, Sameehan U.; Campisi, Laura; Zheng, Simin; Song, Won-Suk; Wang, Ying-chih; Shah, Hardik; Francoeur, Nancy; Soto, Juan; Salfati, Zelda; Weirauch, Matthew T.; Warburton, Peter; Beaumont, Kristin; Smith, Melissa L.; Mulder, Lubbertus; Villalta, S. Armando; Kessenbrock, Kai; Jang, Cholsoon; Lee, Daeyoup; Rubeis, Silvia De; Cobos, Inma; Tam, Oliver; Hammell, Molly Gale; Seldin, Marcus; Shi, Yongsheng; Basu, Uttiya; Sebastiano, Vittorio; Byun, Minji; Sebra, Robert; Rosenberg, Brad R.; Benner, Chris; Guccione, Ernesto; Marazzi, Ivan Share Save
Isoform-resolved transcriptome of the human preimplantation embryo Torre, Denis; Francoeur, Nancy J.; Kalma, Yael; Carmel, Ilana Gross; Melo, Betsaida S.; Deikus, Gintaras; Allette, Kimaada; Flohr, Ron; Fridrikh, Maya; Vlachos, Konstantinos; Madrid, Kent; Shah, Hardik; Wang, Ying-Chih; Sridhar, Shwetha H.; Smith, Melissa L.; Eliyahu, Efrat; Azem, Foad; Amir, Hadar; Mayshar, Yoav; Marazzi, Ivan; Guccione, Ernesto; Schadt, Eric; Ben-Yosef, Dalit; Sebra, Robert Share Save
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