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CoREST complex inhibition alters RNA splicing to promote neoantigen expression and enhance tumor immunity Fisher, Robert J.; Park, Kihyun; Lee, Kwangwoon; Pinjusic, Katarina; Vanasse, Allison; Ennis, Christina S.; Farokh, Parisa; Ficaro, Scott B.; Marto, Jarrod A.; Jiang, Hanjie; Nam, Eunju; Stransky, Stephanie; Duke-Cohan, Joseph; Akinci, Melis A.; Geethadevi, Anupa; Raabe, Eric; Fiszbein, Ana; Demehri, Shadmehr; Sidoli, Simone; Hicks, Chad W.; Keskin, Derin B.; Wu, Catherine J.; Cole, Philip A.; Alani, Rhoda M. Share Save
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HIF regulates multiple translated endogenous retroviruses: Implications for cancer immunotherapy Jiang, Qinqin; Braun, David A.; Clauser, Karl R.; Ramesh, Vijyendra; Shirole, Nitin H.; Duke-Cohan, Joseph E.; Nabilsi, Nancy; Kramer, Nicholas J.; Forman, Cleo; Lippincott, Isabelle E.; Klaeger, Susan; Phulphagar, Kshiti M.; Chea, Vipheaviny; Kim, Nawoo; Vanasse, Allison P.; Saad, Eddy; Parsons, Teagan; Carr-Reynolds, Melissa; Carulli, Isabel; Pinjusic, Katarina; Jiang, Yijia; Li, Rong; Syamala, Sudeepa; Rachimi, Suzanna; Verzani, Eva K.; Stevens, Jonathan D.; Lane, William J.; Camp, Sabrina Y.; Meli, Kevin; Pappalardi, Melissa B.; Herbert, Zachary T.; Qiu, Xintao; Cejas, Paloma; Long, Henry W.; Shukla, Sachet A.; Allen, Eliezer M. Van; Choueiri, Toni K.; Churchman, L. Stirling; Abelin, Jennifer G.; Gurer, Cagan; Macbeath, Gavin; Childs, Richard W.; Carr, Steven A.; Keskin, Derin B.; Wu, Catherine J.; Kaelin Jr, William G. Share Save
A randomized, placebo-controlled trial of the BTK inhibitor zanubrutinib in hospitalized patients with COVID-19 respiratory distress: immune biomarker and clinical findings Treon, Steven P.; Kotton, Camille N.; Park, David J.; Moranzoni, Giorgia; Lemvigh, Camilla K.; Gathe Jr, Joseph C.; Varughese, Tilly A.; Barnett, Christopher F.; Belenchia, Johnny M.; Clark, Nina M.; Farber, Charles M.; Abid, Muhammad Bilal; Ahmed, Gulrayz; Patterson, Christopher J.; Guerrera, Maria L.; Soumerai, Jacob D.; Chea, Vipheaviny A.; Carulli, Isabel P.; Southard, Jackson; Li, Shuqiang; Wu, Catherine J.; Livak, Kenneth J.; Holmgren, Eric; Kim, Pil; Shi, Carrie; Lin, Holly; Ramakrishnan, Vanitha; Ou, Ying; Olszewski, Scott; Olsen, Lars Ronn; Keskin, Derin B.; Hunter, Zachary R.; Tankersley, Christopher; Zimmerman, Todd; Dhakal, Binod Share Save
Systematic identification of minor histocompatibility antigens predicts outcomes of allogeneic hematopoietic cell transplantation Cieri, Nicoletta; Hookeri, Nidhi; Stromhaug, Kari; Li, Liang; Keating, Julia; Diaz-Fernandez, Paula; Gomez-Garcia de Soria, Valle; Stevens, Jonathan; Kfuri-Rubens, Raphael; Shao, Yiren; Kooshesh, Kameron A.; Powell, Kaila; Ji, Helen; Hernandez, Gabrielle M.; Abelin, Jennifer; Klaeger, Susan; Forman, Cleo; Clauser, Karl R.; Sarkizova, Siranush; Braun, David A.; Penter, Livius; Kim, Haesook T.; Lane, William J.; Oliveira, Giacomo; Kean, Leslie S.; Li, Shuqiang; Livak, Kenneth J.; Carr, Steven A.; Keskin, Derin B.; Munoz-Calleja, Cecilia; Ho, Vincent T.; Ritz, Jerome; Soiffer, Robert J.; Neuberg, Donna; Stewart, Chip; Getz, Gad; Wu, Catherine J. Share Save
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Comparative molecular profiling of sporadic and Lynch syndrome MSI tumors: Unraveling insights for vaccine design Ladany, Hagay; Grossman, Mark; Hess, Julian; Lu, Nicole; Keskin, Derin; Wu, Catherine J.; Hacohen, Nir; Gallon, Richard; Burn, John; Hampel, Heather; Stadler, Zsofia; Getz, Gad; Maruvka, Yosef E.; Lipkin, Steven Share Save
Fine tuning of CpG spatial distribution with DNA origami for improved cancer vaccination Zeng, Yang C.; Young, Olivia J.; Wintersinger, Christopher M.; Anastassacos, Frances M.; MacDonald, James I.; Isinelli, Giorgia; Dellacherie, Maxence O.; Sobral, Miguel; Bai, Haiqing; Graveline, Amanda R.; Vernet, Andyna; Sanchez, Melinda; Mulligan, Kathleen; Choi, Youngjin; Ferrante, Thomas C.; Keskin, Derin B.; Fell, Geoffrey G.; Neuberg, Donna; Wu, Catherine J.; Mooney, David J.; Kwon, Ick Chan; Ryu, Ju Hee; Shih, William M. Share Save
CKLF instigates a cold microenvironment to promote MYCN-mediated tumor aggressiveness Qin, Xiaodan; Lam, Andrew; Zhang, Xu; Sengupta, Satyaki; Iorgulescu, J. Bryan; Ni, Hongru; Das, Sanjukta; Rager, Madison; Zhou, Zhenwei; Zuo, Tao; Meara, Grace K.; Floru, Alexander E.; Kemet, Chinyere; Veerapaneni, Divya; Kashy, Daniel; Lin, Liang; Lloyd, Kenneth; Kwok, Lauren; Smith, Kaylee S.; Nagaraju, Raghavendar T.; Meijers, Rob; Ceol, Craig; Liu, Ching-Ti; Alexandrescu, Sanda; Wu, Catherine J.; Keskin, Derin B.; George, Rani E.; Feng, Hui Share Save
Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons Truex, Nicholas L.; Mohapatra, Somesh; Melo, Mariane; Rodriguez, Jacob; Li, Na; Abraham, Wuhbet; Sementa, Deborah; Touti, Faycal; Keskin, Derin B.; Wu, Catherine J.; Irvine, Darrell J.; Gomez-Bombarelli, Rafael; Pentelute, Bradley L. Share Save
Personalized targeted circulating tumor DNA (ctDNA) and T-cell responses after combined neoantigen vaccine and immune checkpoint blockade in ovarian cancer Sellars, MacLean C.; Porter, Rebecca; Liu, Ruolin; Howard, Alexis A.; Xiong, Kan; Crnjac, Andela; Tayob, Nabihah; Keskin, Derin; Adalsteinsson, Vicktor; Wu, Catherine; Konstantinopoulos, Panagiotis Share Save
A tumor-associated chemokine attracts CCR4-expressing CD4+cells to foster immune repression and tumor aggressiveness in MYCN-driven neuroblastoma Qin, Xiaodan; Lam, Andrew; Zhang, Xu; Sengupta, Satyaki; Lorgulescu, J. Bryan; Das, Sanjukta; Zhou, Zhenwei; Zuo, Tao; Meara, Grace K.; Rager, Madison; Floru, Alexander E.; Ni, Hongru; Kemet, Chinyere; Veerapaneni, Divya; Kashy, Daniel; Lin, Liang; Lloyd, Kenneth; Kwok, Lauren; Smith, Kaylee S.; Nagaraju, Raghavendar T.; Meijers, Rob; Ceol, Craig; Liu, Ching-Ti; Alexandrescu, Sanda; Wu, Catherine J.; Keskin, Derin B.; George, Rani E.; Feng, Hui Share Save
Integrated Immunopeptidomic and Proteomic Analysis of COVID-19 lung biopsies Yin, Shanye; Klaeger, Susan; Chea, Vipheaviny A.; Carulli, Isabel P.; Rachimi, Suzanna; Black, Katharine E.; Filbin, Michael; Hariri, Lida P.; Knipe, Rachel S.; Padera, Robert F.; Stevens, Jonathan D.; Lane, William J.; Carr, Steven A.; Wu, Catherine J.; Kim, Edy Yong; Keskin, Derin B. Share Save
The BRD4-NUT Fusion Alone Drives Malignant Transformation of NUT Carcinoma Durall, R. Taylor; Huang, Julianna; Wojenski, Luke; Huang, Yeying; Gokhale, Prafulla C.; Leeper, Brittaney A.; Nash, Joshua O.; Ballester, Pedro L.; Davidson, Scott; Shlien, Adam; Sotirakis, Emmanuel; Bertaux, Fabien; Dubus, Vincent; Luo, Jia; Wu, Catherine J.; Keskin, Derin B.; Eagen, Kyle P.; Shapiro, Geoffrey I.; French, Christopher A. Share Save
Tumor-specific immunity generated by a personalized neoantigen vaccination incorporating locally delivered ipilimumab in renal cell carcinoma. Braun, David A.; Keskin, Derin B.; Shukla, Sachet A.; McGregor, Bradley A.; Schindler, Nicholas R.; Blass, Eryn; Klaeger, Susan; Pomerance, Lucas; Sarkizova, Siranush; Li, Shuqiang; Southard, Jackson; Moranzoni, Giorgia; Pedersen, Christina B.; Liu, Yiwen; Chang, Steven L.; Hirsch, Michelle S.; LeBoeuf, Nicole R.; Mossanen, Matthew; Chea, Vipheaviny; Carulli, Isabel; Olive, Oriol; Mehndiratta, Ambica; Greenslade, Haley; Oliveira, Giacomo; Iorgulescu, J. Bryan; Signoretti, Sabina; Aster, Jon C.; Elagina, Liudmila; Leshchiner, Ignaty; Getz, Gad; Harden, Maegan; Gabriel, Stacey; Olsen, Lars R.; Neuberg, Donna S.; Fritsch, Edward F.; Hacohen, Nir; Livak, Kenneth J.; Carr, Steven; Ott, Patrick A.; Wu, Catherine J.; Choueiri, Toni K. Share Save
Mapping the evolution of T cell states during response and resistance to adoptive cellular therapy (vol 37, 109992, 2021) Bachireddy, Pavan; Azizi, Elham; Burdziak, Cassandra; Nguyen, Vinhkhang N.; Ennis, Christina S.; Maurer, Katie; Park, Cameron Y.; Choo, Zi-Ning; Li, Shuqiang; Gohil, Satyen H.; Ruthen, Neil G.; Ge, Zhongqi; Keskin, Derin B.; Cieri, Nicoletta; Livak, Kenneth J.; Kim, Haesook T.; Neuberg, Donna S.; Soiffer, Robert J.; Ritz, Jerome; Alyea, Edwin P.; Pe'er, Dana; Wu, Catherine J. Share Save
ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer Mota, Ines; Patrucco, Enrico; Mastini, Cristina; Mahadevan, Navin R.; Thai, Tran C.; Bergaggio, Elisa; Cheong, Taek-Chin; Leonardi, Giulia; Karaca-Atabay, Elif; Campisi, Marco; Poggio, Teresa; Menotti, Matteo; Ambrogio, Chiara; Longo, Dario L.; Klaeger, Susan; Keshishian, Hasmik; Sztupinszki, Zsofia M.; Szallasi, Zoltan; Keskin, Derin B.; Duke-Cohan, Jonathan S.; Reinhold, Bruce; Carr, Steven A.; Wu, Catherine J.; Moynihan, Kelly D.; Irvine, Darrell J.; Barbie, David A.; Reinherz, Ellis L.; Voena, Claudia; Awad, Mark M.; Blasco, Rafael B.; Chiarle, Roberto Share Save
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