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Lynne E. Maquat

University of Rochester

81H-index
265Paper Count
2.3WCitation Count
Published Papers 88
Publication Date
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TDP-43 dysfunction compromises UPF1-dependent mRNA metabolism in ALS
errNeuron
IF15
err2025-12-12
err0
errOAAI
errFrancesco Alessandrini; Matthew Wright; Tatsuaki Kurosaki; Olga S. Perloff; Marilyn Ngo; Julia K. Kofler; Christopher J. Donnelly; Lynne E. Maquat; Evangelos Kiskinis
errShare
errSave
Gene regulation through exon junction complex modularity
errNature Structural & Molecular Biology
IF10.1
err2025-12-03
err0
PREAI
errElizabeth T. Abshire; Lynne E. Maquat
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errSave
FMRP drives mRNP targets into translationally silenced complexes
errMolecular Cell
IF16.6
err2025-07-10
err0
PREAI
errTatsuaki Kurosaki; Hana Cho; Elizabeth T. Abshire; Christoph Pröschel; Shuhei Mitsutomi; Hanae Sato; Eric A.J. Simko; Christopher S. Fraser; Hitomi Sakano; Lynne E. Maquat
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errSave
Exploring the therapeutic potential of modulating nonsense-mediated mRNA decay
errRNA
IF5
err2024-12-12
err0
PREAI
errMcmahon, Mary; Maquat, Lynne E.
errShare
errSave
Nuclear mRNA decay: regulatory networks that control gene expression
errNATURE REVIEWS GENETICS
IF52
err2024-04-18
err3
errOAAI
errRambout, Xavier; Maquat, Lynne E.
errShare
errSave
FMRP-mediated spatial regulation of physiologic NMD targets in neuronal cells
errGENOME BIOLOGY
IF9.4
err2024-01-23
err0
errOAAI
errKurosaki, Tatsuaki; Rambout, Xavier; Maquat, Lynne E.
errShare
errSave
Selenium deficiency reduces the abundance of mRNA for Se-dependent glutathione peroxidase 1 by a UGA-dependent mechanism likely to be nonsense codon-mediated decay of cytoplasmic mRNA
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err217
errOAAI
errMoriarty, PM; Reddy, CC; Maquat, LE
errShare
errSave
Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4)
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err248
errOAAI
errSerin, G; Gersappe, A; Black, JD; Aronoff, R; Maquat, LE
errShare
errSave
At least one intron is required for the nonsense-mediated decay of triosephosphate isomerase mRNA: a possible link between nuclear splicing and cytoplasmic translation
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err265
errOAAI
errZhang, J; Sun, XL; Qian, YM; LaDuca, JP; Maquat, LE
errShare
errSave
Evidence that poly(A) binding protein C1 binds nuclear pre-mRNA poly(A) tails
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err100
errOAAI
errHosoda, N; Lejeune, F; Maquat, LE
errShare
errSave
Regulation of multiple core spliceosomal proteins by alternative splicing-coupled nonsense-mediated mRNA decay
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err198
errOAAI
errSaltzman, Arneet L.; Kim, Yoon Ki; Pan, Qun; Fagnani, Matthew M.; Maquat, Lynne E.; Blencowe, Benjamin J.
errShare
errSave
PGC-1a senses the CBC of pre-mRNA to dictate the fate of promoter-proximally paused RNAPII
errMOLECULAR CELL
IF16.6
err2023-01-01
err10
errOAAI
errRambout, Xavier; Cho, Hana; Blanc, Romeo; Lyu, Qing; Miano, Joseph M.; Chakkalakal, Joe V.; Nelson, Geoffrey M.; Yalamanchili, Hari K.; Adelman, Karen; Maquat, Lynne E.
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errSave
Integrative omics indicate FMRP sequesters mRNA from translation and deadenylation in human neuronal cells
errMOLECULAR CELL
IF16.6
err2022-12-01
err10
errOAAI
errKurosaki, Tatsuaki; Mitsutomi, Shuhei; Hewko, Alexander; Akimitsu, Nobuyoshi; Maquat, Lynne E.
errShare
errSave
AKT constitutes a signal-promoted alternative exon-junction complex that regulates nonsense-mediated mRNA decay
errMOLECULAR CELL
IF16.6
err2022-08-01
err18
errOAAI
errCho, Hana; Abshire, Elizabeth T.; Popp, Maximilian W.; Proschel, Christoph; Schwartz, Joshua L.; Yeo, Gene W.; Maquat, Lynne E.
errShare
errSave
Noncoding RNAs: biology and applications-a Keystone Symposia report
errANNALS OF THE NEW YORK ACADEMY OF SCIENCES
IF4.8
err2021-11-17
err16
errOAAI
errCable, Jennifer; Heard, Edith; Hirose, Tetsuro; Prasanth, Kannanganattu, V; Chen, Ling-Ling; Henninger, Jonathan E.; Quinodoz, Sofia A.; Spector, David L.; Diermeier, Sarah D.; Porman, Allison M.; Kumar, Dhiraj; Feinberg, Mark W.; Shen, Xiaohua; Unfried, Juan Pablo; Johnson, Rory; Chen, Chun-Kan; Wilusz, Jeremy E.; Lempradl, Adelheid; McGeary, Sean E.; Wahba, Lamia; Pyle, Anna Marie; Hargrove, Amanda E.; Simon, Matthew D.; Marcia, Marco; Przanowska, Roza K.; Chang, Howard Y.; Jaffrey, Samie R.; Contreras, Lydia M.; Chen, Qi; Shi, Junchao; Mendell, Joshua T.; He, Lin; Song, Erwei; Rinn, John L.; Lalwani, Mukesh Kumar; Kalem, Murat Can; Chuong, Edward B.; Maquat, Lynne E.; Liu, Xuhang
errShare
errSave
NMD abnormalities during brain development in the Fmr1-knockout mouse model of fragile X syndrome
errGENOME BIOLOGY
IF9.4
err2021-11-16
err7
errOAAI
errKurosaki, Tatsuaki; Sakano, Hitomi; Proschel, Christoph; Wheeler, Jason; Hewko, Alexander; Maquat, Lynne E.
errShare
errSave
NCBP3: A Multifaceted Adaptive Regulator of Gene Expression
errTRENDS IN BIOCHEMICAL SCIENCES
IF11
err2021-02-01
err8
errOAAI
errRambout, Xavier; Maquat, Lynne E.
errShare
errSave
Loss of the fragile X syndrome protein FMRP results in misregulation of nonsense-mediated mRNA decay
errNATURE CELL BIOLOGY
IF19.1
err2021-01-08
err31
errOAAI
errKurosaki, Tatsuaki; Imamachi, Naoto; Proschel, Christoph; Mitsutomi, Shuhei; Nagao, Rina; Akimitsu, Nobuyoshi; Maquat, Lynne E.
errShare
errSave
3′READS plus RIP defines differential Staufen1 binding to alternative 3′UTR isoforms and reveals structures and sequence motifs influencing binding and polysome association
errRNA
IF5
err2020-08-12
err7
errOAAI
errZheng, Dinghai; Cho, Hana; Wang, Wei; Rambout, Xavier; Tian, Bin; Maquat, Lynne E.
errShare
errSave
Viral subversion of nonsense-mediated mRNA decay
errRNA
IF5
err2020-07-22
err26
errOAAI
errPopp, Maximilian Wei-Lin; Cho, Hana; Maquat, Lynne E.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
H
Howard Y. Chang
H-index: 162 · Papers: 736
R
Rory Johnson
H-index: 110 · Papers: 263
H
Harry C. Dietz
H-index: 108 · Papers: 395
G
G Yeo
H-index: 104 · Papers: 1.4K
J
John L. Rinn
H-index: 100 · Papers: 289
View more