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J

J Engreitz

Broad Institute of MIT and Harvard

43H-index
471Paper Count
1.7WCitation Count
Published Papers 41
Publication Date
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Mapping enhancer–gene regulatory interactions from single-cell data
errNature Genetics
IF29
err2026-08-03
err0
errOAAI
errMaya U. Sheth; Wei-Lin Qiu; X. Rosa Ma; Andreas R. Gschwind; Evelyn Jagoda; Anthony S. Tan; James Galante; Judhajeet Ray; Dulguun Amgalan; Hjörleifur Einarsson; Bram L. Gorissen; Danilo Dubocanin; Christopher S. McGinnis; Jacob Huang; Glen Munson; Kayla Brand; Ansuman T. Satpathy; Thouis R. Jones; Lars M. Steinmetz; Anshul Kundaje; Berk Ustun; Jesse M. Engreitz; Robin Andersson
errShare
errSave
An encyclopedia of human enhancer–gene regulatory interactions
errNature
IF48.5
err2026-07-15
err0
errOAAI
errAndreas R. Gschwind; Kristy S. Mualim; Alireza Karbalayghareh; Maya U. Sheth; Kushal K. Dey; Evelyn Jagoda; Ramil N. Nurtdinov; Wang Xi; Anthony S. Tan; James Galante; Hank Jones; X. Rosa Ma; David Yao; Dulguun Amgalan; Judhajeet Ray; Chad J. Munger; Joseph Nasser; Žiga Avsec; Benjamin T. James; Muhammad S. Shamim; Neva C. Durand; Suhas S. P. Rao; Ragini Mahajan; Benjamin R. Doughty; Kalina Andreeva; Jacob C. Ulirsch; Kaili Fan; Elizabeth M. Perez; Tri C. Nguyen; David R. Kelley; Hilary K. Finucane; Jill E. Moore; Zhiping Weng; Manolis Kellis; Michael C. Bassik; Berk Ustun; Alkes L. Price; Michael A. Beer; Roderic Guigó; John A. Stamatoyannopoulos; Erez Lieberman Aiden; William J. Greenleaf; Christina S. Leslie; Lars M. Steinmetz; Anshul Kundaje; Jesse M. Engreitz
errShare
errSave
Junction-targeting designs limit the application of CRISPR-Cas13d in circular RNA perturbation studies
errNucleic Acids Research
IF13.1
err2026-01-13
err3
PREAI
errLee-yow, Yannick C.; Valbuena, Raeline C.; Richter, Chiara S.; Chang, Howard Y.; Engreitz, Jesse M.
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errSave
An expanded registry of candidate cis-regulatory elements
errNature
IF48.5
err2026-01-07
err0
errOAAI
errJill E. Moore; Henry E. Pratt; Kaili Fan; Nishigandha Phalke; Jonathan Fisher; Shaimae I. Elhajjajy; Gregory Andrews; Mingshi Gao; Nicole Shedd; Yu Fu; Matthew C. Lacadie; Jair Meza; Mansi Khandpekar; Mohit Ganna; Eva Choudhury; Ross Swofford; Huong Phan; Christian C. Ramirez; Maxwell Campbell; Mary Likhite; Nina P. Farrell; Annika K. Weimer; Anusri Pampari; Vivekanandan Ramalingam; Fairlie Reese; Beatrice Borsari; Xuezhu Yu; Eve Wattenberg; Marina Ruiz-Romero; Milad Razavi-Mohseni; Jinrui Xu; Timur Galeev; Andres Colubri; Michael A. Beer; Roderic Guigó; Mark B. Gerstein; Jesse M. Engreitz; Mats Ljungman; Timothy E. Reddy; Michael P. Snyder; Charles B. Epstein; Elizabeth Gaskell; Bradley E. Bernstein; Diane E. Dickel; Axel Visel; Len A. Pennacchio; Ali Mortazavi; Anshul Kundaje; Zhiping Weng
errShare
errSave
The IGVF catalog-from genetic variation to function
errNUCLEIC ACIDS RESEARCH
IF13.1
err2025-12-01
err1
PREAI
errLi, Daofeng; Liu, Shane; Assis, Pedro R.; Li, Mingjie; Dong, Shengcheng; Whaling, Ian; Jolanki, Otto; Kagda, Meenakshi; Zhang, Wenjin; Macias-Velasco, Juan F.; Liu, Tianjie; Cody, Sarah; Antonacci-Fulton, Lucinda; Huang, Yuanhao; Liu, Jie; Montgomery, Michael T.; Zeiberg, Daniel; Jain, Shantanu; Pejaver, Vikas; Bergquist, Timothy; Chen, Yile; Radivojac, Predrag; Gersbach, Charles A.; Sherpa, Rintsen N.; Castro, Christopher P.; Boyle, Alan P.; Starita, Lea M.; Fowler, Douglas M.; Ahituv, Nadav; Dey, Kushal K.; Majoros, William H.; Reddy, Timothy E.; Craven, Mark; Sinha, Riya; Sverchkov, Yuriy; Cai, Xiangmeng; Nzima, Mpathi Z.; Calderwood, Michael A.; Rozowsky, Joel; Gerstein, Mark; Ma, Jian; Yue, Feng; Cherry, J. Michael; Love, Michael, I; Engreitz, Jesse M.; Hitz, Benjamin C.; Wang, Ting
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errSave
Variant-enhancer-gene mapping at the 9p21 locus in smooth muscle cells reveals new enhancer-gene pairs and mechanistic insights for coronary artery disease
errCIRCULATION
IF38.6
err2024-11-12
err0
PREAI
errRamste, Markus; Weldy, Chad; Zhao, Quanyi; Ranta, Amanda; Li, Daniel; Sharma, Disha; Monteiro, Joao; Worssam, Matthew; Amgalan, Dulguun; Qin, Guyu; Nguyen, Trieu; Kim, Juyong; Engreitz, Jesse; Assimes, Themistocles; Park, Chong; Quertermous, Thomas
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errSave
SOX17 Deficiency is Additive to High Shear Stress in Reducing Endothelial Genes Linked to BMPR2 and NOTCH and Promoting Inflammation in Pulmonary Arterial Hypertension
errCIRCULATION
IF38.6
err2024-11-12
err0
PREAI
errZhang, Chongyang; Shinohara, Tsutomu; Leeyow, Yannick; Guo, Kathrine; Lago-Docampo, Mauro; Engreitz, Jesse; Rabinovitch, Marlene
errShare
errSave
Selective Enhancer Gain-of-Function Deregulates MYC Expression in Multiple Myeloma
errCANCER RESEARCH
IF16.6
err2024-09-23
err0
PREAI
errRahmat, Mahshid; Clement, Kendell; Alberge, Jean-Baptiste; Sklavenitis-Pistofidis, Romanos; Kodgule, Rohan; Fulco, Charles P.; Heilpern-Mallory, Daniel; Nilsson, Katarina; Dorfman, David; Engreitz, Jesse M.; Getz, Gad; Pinello, Luca; Ryan, Russell J. H.; Ghobrial, Irene M.
errShare
errSave
Genetic and functional analysis of Raynaud's syndrome implicates loci in vasculature and immunity
errCELL GENOMICS
IF9
err2024-09-01
err0
errOAAI
errTervi, Anniina; Ramste, Markus; Abner, Erik; Cheng, Paul; Lane, Jacqueline M.; Maher, Matthew; Valliere, Jesse; Lammi, Vilma; Strausz, Satu; Riikonen, Juha; Nguyen, Trieu; Martyn, Gabriella E.; Sheth, Maya U.; Xia, Fan; Docampo, Mauro Lago; Gu, Wenduo; Esko, Tonu; Saxena, Richa; Pirinen, Matti; Palotie, Aarno; Ripatti, Samuli; Sinnott-Armstrong, Nasa; Daly, Mark; Engreitz, Jesse M.; Rabinovitch, Marlene; Heckman, Caroline A.; Quertermous, Thomas; Jones, Samuel E.; Ollila, Hanna M.
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errSave
Single Cell Transcriptional And Epigenetic Map Of Human Coronary Artery Disease In A Multi-ethnic Population
errARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
IF7.4
err2024-05-01
err0
PREAI
errAmrute, Junedh M.; Lee, Paul; Eres, Ittai; Bredemeyer, Andrea; Yamawaki, Tracy; Kang, Chul Joo; Lee, Mick J.; Gurung, Rijan; Li, Daniel; Zhao, Quanyi; Sheth, Maya; Tan, Anthony; Gschwind, Andreas; Cheng, Paul; Jackson, Simon; Hsu, Yi-Hsiang; Foo, Roger; Hall, Ira; Gupta, Rajat M.; Engreitz, Jesse; Li, Chi-Ming; Quertermous, Thomas; Ason, Brandon; Lavine, Kory J.; Stitziel, Nathan O.
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errSave
Multicenter integrated analysis of noncoding CRISPRi screens
errNATURE METHODS
IF32.1
err2024-03-19
err10
errOAAI
errYao, David; Tycko, Josh; Oh, Jin Woo; Bounds, Lexi R.; Gosai, Sager J.; Lataniotis, Lazaros; Mackay-Smith, Ava; Doughty, Benjamin R.; Gabdank, Idan; Schmidt, Henri; Guerrero-Altamirano, Tania; Siklenka, Keith; Guo, Katherine; White, Alexander D.; Youngworth, Ingrid; Andreeva, Kalina; Ren, Xingjie; Barrera, Alejandro; Luo, Yunhai; Yardimci, Galip Gurkan; Tewhey, Ryan; Kundaje, Anshul; Greenleaf, William J.; Sabeti, Pardis C.; Leslie, Christina; Pritykin, Yuri; Moore, Jill E.; Beer, Michael A.; Gersbach, Charles A.; Reddy, Timothy E.; Shen, Yin; Engreitz, Jesse M.; Bassik, Michael C.; Reilly, Steven K.
errShare
errSave
Reduced FOXF1 links unrepaired DNA damage to pulmonary arterial hypertension
errNATURE COMMUNICATIONS
IF15.7
err2023-11-21
err4
errOAAI
errIsobe, Sarasa; Nair, Ramesh V.; Kang, Helen Y.; Wang, Lingli; Moonen, Jan-Renier; Shinohara, Tsutomu; Cao, Aiqin; Taylor, Shalina; Otsuki, Shoichiro; Marciano, David P.; Harper, Rebecca L.; Adil, Mir S.; Zhang, Chongyang; Lago-Docampo, Mauro; Koerbelin, Jakob; Engreitz, Jesse M.; Snyder, Michael P.; Rabinovitch, Marlene
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errSave
Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases
errNATURE GENETICS
IF31.8
err2023-07-13
err55
errOAAI
errWeeks, Elle M. M.; Ulirsch, Jacob C. C.; Cheng, Nathan Y. Y.; Trippe, Brian L. L.; Fine, Rebecca S. S.; Miao, Jenkai; Patwardhan, Tejal A. A.; Kanai, Masahiro; Nasser, Joseph; Fulco, Charles P. P.; Tashman, Katherine C. C.; Aguet, Francois; Li, Taibo; Ordovas-Montanes, Jose; Smillie, Christopher S. S.; Biton, Moshe; Shalek, Alex K. K.; Ananthakrishnan, Ashwin N. N.; Xavier, Ramnik J. J.; Regev, Aviv; Gupta, Rajat M. M.; Lage, Kasper; Ardlie, Kristin G. G.; Hirschhorn, Joel N. N.; Lander, Eric S. S.; Engreitz, Jesse M. M.; Finucane, Hilary K. K.
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errSave
Genetic Determinants of the Interventricular Septum Are Linked to Ventricular Septal Defects and Hypertrophic Cardiomyopathy
errCIRCULATION-GENOMIC AND PRECISION MEDICINE
IF5.5
err2023-06-01
err3
errOAAI
errYu, Mengyao; Harper, Andrew R.; Aguirre, Matthew; Pittman, Maureen; Tcheandjieu, Catherine; Amgalan, Dulguun; Grace, Christopher; Goel, Anuj; Farrall, Martin; Xiao, Ke; Engreitz, Jesse; Pollard, Katherine S.; Watkins, Hugh; Priest, James R.
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errSave
Oligogenic Architecture of Rare Noncoding Variants Distinguishes 4 Congenital Heart Disease Phenotypes
errCIRCULATION-GENOMIC AND PRECISION MEDICINE
IF5.5
err2023-06-01
err3
errOAAI
errYu, Mengyao; Aguirre, Matthew; Jia, Meiwen; Gjoni, Ketrin; Cordova-Palomera, Aldo; Munger, Chad; Amgalan, Dulguun; Ma, X. Rosa; Pereira, Alexandre; Tcheandjieu, Catherine; Seidman, Christine; Seidman, Jonathan; Tristani-Firouzi, Martin; Chung, Wendy; Goldmuntz, Elizabeth; Srivastava, Deepak; Loos, Ruth J. F.; Chami, Nathalie; Cordell, Heather; Dressen, Martina; Mueller-Myhsok, Bertram; Lahm, Harald; Krane, Markus; Pollard, Katherine S.; Engreitz, Jesse M.; Taliun, Sarah Gagliano A.; Gelb, Bruce D.; Priest, James R.
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errSave
CRISPRi- Perturb-seq In Endothelial Cells Links Atherosclerosis Risk Loci To Novel Klf2/4 Regulatory Genes
errARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
IF7.4
err2023-05-01
err0
PREAI
errGupta, Rajat M.; Schnitzler, Gavin R.; Kang, Helen; Angom, Ramcharan Singh; Fang, Shi; Lee-Kim, Vivian; Zheng, Tony; Ma, Rosa; Barry, Aurelie; Zhou, Ronghao; Mukhopadhyay, Debabrata; Engreitz, Jesse
errShare
errSave
Identifying disease-critical cell types and cellular processes by integrating single-cell RNA-sequencing and human genetics
errNATURE GENETICS
IF31.8
err2022-09-29
err57
errOAAI
errJagadeesh, Karthik A.; Dey, Kushal K.; Montoro, Daniel T.; Mohan, Rahul; Gazal, Steven; Engreitz, Jesse M.; Xavier, Ramnik J.; Price, Alkes L.; Regev, Aviv
errShare
errSave
SNP-to-gene linking strategies reveal contributions of enhancer-related and candidate master-regulator genes to autoimmune disease
errCELL GENOMICS
IF9
err2022-07-01
err14
errOAAI
errDey, Kushal K.; Gazal, Steven; van de Geijn, Bryce; Kim, Samuel Sungil; Nasser, Joseph; Engreitz, Jesse M.; Price, Alkes L.
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errSave
Combining SNP-to-gene linking strategies to identify disease genes and assess disease omnigenicity
errNATURE GENETICS
IF31.8
err2022-06-06
err62
errOAAI
errGazal, Steven; Weissbrod, Omer; Hormozdiari, Farhad; Dey, Kushal K.; Nasser, Joseph; Jagadeesh, Karthik A.; Weiner, Daniel J.; Shi, Huwenbo; Fulco, Charles P.; O'Connor, Luke J.; Pasaniuc, Bogdan; Engreitz, Jesse M.; Price, Alkes L.
errShare
errSave
Computational estimates of annular diameter reveal genetic determinants of mitral valve function and disease
errJCI INSIGHT
IF6.1
err2022-02-08
err6
errOAAI
errYu, Mengyao; Tcheandjieu, Catherine; Georges, Adrien; Xiao, Ke; Tejeda, Helio; Dina, Christian; Le Tourneau, Thierry; Fiterau, Madalina; Judy, Renae; Tsao, Noah L.; Amgalan, Dulguun; Munger, Chad J.; Engreitz, Jesse M.; Damrauer, Scott M.; Bouatia-Naji, Nabila; Priest, James R.
errShare
errSave

Research Directions

No research directions
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