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R

Ruth Plummer

Newcastle University and Newcastle Hospitals NHS Foundation Trust

59H-index
604Paper Count
1.4WCitation Count
Published Papers 186
Publication Date
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Oncology drug development in the UK: analysis of the past 25 years and focus on the 2026 reboot of the clinical trial regulatory framework
errBritish Journal of Cancer
IF6.8
err2026-07-23
err0
errOAAI
errPaulina Czajka-Francuz; Chris Twelves; James Spicer; Archana Munje; Laura Vidal; Ruth Plummer; Dinesh Mistry; Maksym Novikov; Jim Bush; Gopalakrishnan Srinivasan; Soma Das; Sharan Sandhu; Vikram Bohra; Chinmayee Joshi; Ken Morrison; Suvarna Chavan; Fiona Thistlethwaite; Andrew Walding; Glen Clack; Michael George; Debashis Sarker; Raghib Ali; Sarah P. Blagden; Thomas R. Jeffry Evans; Kamal S. Saini
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Safety and Efficacy of HexaBody-DR5/DR5 in Malignant Solid Tumors: Phase 1/2a Results and Translational Insights Into Observed Hepatotoxicity
errClinical and Translational Science
IF2.8
err2026-05-22
err0
errOAAI
errMarije B. Overdijk; Kristin Strumane; Ruth Plummer; Patricia LoRusso; Jordi Rodon Ahnert; Udai Banerji; Elena Garralda; Emiliano Calvo; Han Si; Naomi Hoevenaars; Jens Thing Mortensen; Sieto Bosgra; Anders Malmberg; Merete Ellekilde-Pedersen; Teresa Ramirez-Andersen; Panagiota Diamantopoulou Reiter; Elena Favaro; Ulf Forssmann; Esther C. W. Breij; Maria Jure-Kunkel
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An Integrated Nonclinical and Clinical Risk Assessment of the Effects of Investigational ATRi Tuvusertib on QTc Interval in Patients With Solid Tumors
errCTS-Clinical and Translational Science
IF2.8
err2026-02-10
err0
errOAAI
errMukker, Jatinder Kaur; Yap, Timothy A.; Tolcher, Anthony W.; de Bono, Johann S.; Plummer, Ruth; Grosser, Gary; van Amsterdam, Christoph; Schieferstein, Hanno; Witjes, Han; Diderichsen, Paul Matthias; Krebs-Brown, Axel; Gao, Wei; Strotmann, Rainer; Szucs, Zoltan; Gounaris, Ioannis; Venkatakrishnan, Karthik
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Multimodal AI and tumour microenvironment integration predicts metastasis in cutaneous melanoma
errNature Communications
IF15.7
err2025-11-18
err0
errOAAI
errTom W. Andrew; Marc Combalia; Carlos Hernandez; Sydney Grant; Gyorgy Paragh; Susanna Puig; Grant Mc Arthur; Grant Richardson; Phil Sloan; Sophia Z. Shalhout; Ruth Plummer; Penny E. Lovat
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errSave
Supporting development of novel brain tumour therapies through global collaboration: early insights from a novel therapeutics accelerator
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errAitken, Charlotte; Bushby, Katie; Goetz, Camille; Huskens, Nicky; Noble, Karen; Hamerlik, Petra; Kaye, Edward; Kobayashi, Dione; Matthew, Ryan; Nazarian, Javad; Plummer, Ruth; Rahman, Ruman; Romero, Artie; Lopez, Juanita; Nagaraju, Kanneboyina
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errSave
Phase I/II Study of AXL-Specific Antibody-Drug Conjugate Enapotamab Vedotin in Patients with Advanced Solid Tumors
errCancer Research Communications
IF0
err2025-11-01
err0
errOAAI
errRohrberg, Kristoffer Staal; Lopez, Juanita S.; Milhem, Mohammed M.; Blank, Christian U.; Reijers, Irene; Thistlethwaite, Fiona; Plummer, Ruth; Piha-Paul, Sarina A.; Janne, Pasi A.; Shum, Elaine; Shaw, Heather M.; Debruyne, Philip R.; Lao, Cristopher; Baurain, Jean-Francois; Choe, Jennifer H.; Gort, Eelke; Zhao, Yujie; Jerusalem, Guy; Schoffski, Patrick; Chen, Andrew William; Cohen, Eric A.; Mankowski, Walter C.; Roshkovan, Leonid; Katz, Sharyn I.; Kontos, Despina; Brady, Lauren K.; Qutaish, Mohammed; Castro, Patricia Garrido; Pencheva, Nora; Bajaj, Gaurav; Fu, Yali; Windfeld, Kristian; Reiter, Panagiota; Jure-Kunkel, Maria; Higgs, Brandon W.; Amiri, Katayoun I.; Ahmadi, Tahamtan; Forssmann, Ulf; Ramalingam, Suresh S.; Vergote, Ignace
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EP18.01 GLOBAL COLLABORATION TO SUPPORT THE TRANSLATION OF BRAIN TUMOUR THERAPIES: EARLY IMPACT AND LEARNINGS FROM A NOVEL THERAPEUTICS ACCELERATOR.
errNeuro-Oncology
IF13.4
err2025-10-03
err0
errOAAI
errC K Aitken; K Bushby; C Goetz; N Huskens; D Kobayashi; R K Mathew; K Noble; R Plummer; R Rahman; A Romero
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errSave
AN INTERNATIONAL NOVEL THERAPEUTICS ACCELERATOR FOR BRAIN TUMOURS: EARLY IMPACT AND LESSONS LEARNED
errNeuro-Oncology
IF13.4
err2025-09-02
err0
errOAAI
errCharlotte Aitken; Katie Bushby; Camille Goetz; Petra Hamerlik; Nicky Huskens; Edward Kaye; Dione Kobayashi; Ryan Mathew; Javad Nazarian; Karen Noble; Ruth Plummer; Ruman Rahman; Artie Romero; Juanita Lopez; Kanneboyina Nagaraju
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errSave
IUC24410-76 Early PSA suppression with adjuvant abiraterone in high-risk prostate cancer: real-world data on the achievement of ultralow PSA levels
errThe Oncologist
IF0
err2025-08-29
err0
errOAAI
errF Di Costanzo; D Alaimo; R Pearson; J Frew; X Jiang; R Plummer; A Greystoke; C Oing; R Chandler; P Rescigno
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errSave
Integrated Population Pharmacokinetic, Pharmacodynamic, and Safety Analyses to Inform Dosage Selection in the Clinical Development of the ATR Inhibitor Tuvusertib
errClinical Pharmacology & Therapeutics
IF5.5
err2025-08-21
err0
errOAAI
errJatinder Kaur Mukker; Paul Matthias Diderichsen; Farina Hellmann; Timothy A. Yap; Ruth Plummer; Anthony W. Tolcher; Johann S. de Bono; Ioannis Gounaris; Zoltan Szucs; Astrid Zimmermann; Irina Kareva; Jayaprakasam Bolleddula; Annick Seithel-Keuth; Giuseppe Locatelli; Marta Enderlin; Christine Hicking; Anup Zutshi; Wei Gao; Rainer Strotmann; Lisa Benincosa; Karthik Venkatakrishnan
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errSave
Overcoming the barriers to treatment of rare cancer patients in the era of precision oncology: A call to action
errCancer Treatment Reviews
IF10.5
err2025-08-14
err0
errOAAI
errWinette T.A. van der Graaf; Nina S. Heiss; Carolyn L. Hynes; Simone P. Keller; Ariane Weinman; Jean-Yves Blay; Pedro Franco; Rachel H. Giles; Denis Lacombe; Philipp Schlatter; David M. Thomas; Sahar Barjesteh van Waalwijk van Doorn-Khosrovani; Max Williamson; Ruth Plummer
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errSave
A phase 1/2a dose-finding study and biomarker assessment of oral lisavanbulin in patients with high-grade glioma or glioblastoma
errCell Reports Medicine
IF10.6
err2025-06-17
err0
errOAAI
errJuanita Suzanne Lopez; Simon Haefliger; Ruth Plummer; Paul M. Clement; Thomas R. Jeffry Evans; Heinz Läubli; Patrick Roth; Rebecca Kristeleit; Lucy Brazil; Ghazaleh Tabatabai; Antje Wick; Benjamin Wunderlich; Kirk Beebe; Joel Robert Eisner; Heidi Lane; Marc Engelhardt; Thomas Kaindl; Peter Hau; Thomas Hundsberger; Joachim Steinbach
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The DNA-PK inhibitor AZD7648 alone or combined with pegylated liposomal doxorubicin in patients with advanced cancer: results of a first-in-human Phase I/IIa study
errBRITISH JOURNAL OF CANCER
IF6.8
err2025-05-17
err0
errOAAI
errYap, Timothy A.; LoRusso, Patricia; Miller, Rowan E.; Kristeleit, Rebecca; Paulovich, Amanda G.; McMorn, Stephen; O'Connor, Lenka Oplustil; Lombardi, Benedetta; Marco-Casanova, Paola; Gangl, Eric T.; Patel, Bharat; O'Connor, Mark J.; Dean, Emma; Zviezdin, Roman; Plummer, Ruth
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TIMEPOINT, a phase 1 study combining MTL-CEBPA with pembrolizumab, supports the immunomodulatory effect of MTL-CEBPA in solid tumors
errCELL REPORTS MEDICINE
IF10.6
err2025-04-01
err0
errOAAI
errPlummer, Ruth; Sodergren, Mikael H.; Hodgson, Rose; Ryan, Brid M.; Raulf, Nina; Nicholls, Joanna P.; Reebye, Vikash; Voutila, Jon; Sinigaglia, Laura; Meyer, Tim; Pinato, David J.; Sarker, Debashis; Basu, Bristi; Blagden, Sarah; Cook, Natalie; Evans, Thomas R. Jeffrey; Yachnin, Jeffrey; Chee, Cheng E.; Li, Daneng; El-Khoueiry, Anthony; Diab, Maria; Huang, Kai-Wen; Pai, Madhava; Spalding, Duncan; Talbot, Thomas; Noel, Marcus S.; Keenan, Bridget; Mahalingam, Devalingam; Song, Min-Sun; Grosso, Melanie; Arnaud, Denis; Auguste, Aurelie; Zacharoulis, Dimitris; Storkholm, Jan; Mcneish, Iain; Habib, Robert; Rossi, John J.; Habib, Nagy A.
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A multivariable disease-specific model enhances prognostication beyond current Merkel cell carcinoma staging: An international cohort study of 10,958 patients
errJOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
IF11.8
err2025-03-01
err1
errOAAI
errAndrew, Tom W.; Erdmann, Sophie; Alrawi, Mogdad; Plummer, Ruth; Shalhout, Sophia Z.; Sondak, Vern; Brownell, Isaac; Lovat, Penny E.; Rose, Aidan
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errSave
A hybrid machine learning approach for the personalized prognostication of aggressive skin cancers
errNPJ DIGITAL MEDICINE
IF15.1
err2025-01-08
err0
errOAAI
errAndrew, Tom W.; Alrawi, Mogdad; Plummer, Ruth; Sondak, Vern; Brownell, Isaac; Lovat, Penny E.; Rose, Aidan; Shalhout, Sophia Z.
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errSave
AN INTERNATIONAL ACCELERATOR PROGRAMME FOR RESEARCHERS DEVELOPING NOVEL THERAPIES FOR BRAIN TUMOURS
errNEURO-ONCOLOGY
IF13.4
err2024-11-11
err0
PREAI
errAitken, Charlotte; Huskens, Nicky; Bushby, Katie; Noble, Karen; Hamerlik, Petra; Kaye, Edward; Kobayashi, Dione; Mathew, Ryan; Mccall, John; Nazarian, Javad; Plummer, Ruth; Rahman, Ruman; Lopez, Juanita; Nagaraju, Kanneboyina
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errSave
AN INTERNATIONAL ACCELERATOR PROGRAMME FOR NOVEL BRAIN TUMOUR THERAPIES
errNEURO-ONCOLOGY
IF13.4
err2024-10-17
err0
PREAI
errAitken, C. K.; Huskens, N.; Bushby, K.; Noble, K.; Hamerlik, P.; Kobayashi, D.; Mathew, R.; McCall, J.; Plummer, R.; Rahman, R.; Lopez, J.
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errSave
A Phase 1a/1b Study of Fostroxacitabine Bralpamide (Fostrox) Monotherapy in Hepatocellular Carcinoma and Solid Tumor Liver Metastases
errJOURNAL OF HEPATOCELLULAR CARCINOMA
IF3.4
err2024-10-01
err0
errOAAI
errPlummer, Ruth; Greystoke, Alastair; Naylor, Gregory; Sarker, Debashis; Anam, A. N. M. Kaiser; Prenen, Hans; Teuwen, Laure-Anne; Van Cutsem, Eric; Dekervel, Jeroen; Haugk, Beate; Ness, Thomas; Bhoi, Sujata; Jensen, Malene; Morris, Tom; Baumann, Pia; Sjogren, Niclas; Tunblad, Karin; Wallberg, Hans; Oberg, Fredrik; Evans, Thomas R. Jeffry
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Translational, PK, PD, and immunophenotyping analyses of tuvusertib plus niraparib in a phase Ib open-label multicenter dose-escalation study in patients with advanced solid tumors (DDRiver Solid Tumors 301)
errANNALS OF ONCOLOGY
IF65.4
err2024-09-01
err0
PREAI
errTolcher, A. W.; Yap, T. A.; Plummer, R.; Sommerhalder, D.; Rodon, J.; Lagonera, M.; Bergmann, P.; Perez, V. Sanchez; Wohlfeil, N.; Wang, D.; Mukker, J. Kaur; Sessa, G.; Manginelli, A.; de Bono, J. S.
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Research Directions

No research directions
Co-authors
Cooperation Journals
D
Dirk Schadendorf
H-index: 182 · Papers: 2.4K
E
Eric Van Cutsem
H-index: 174 · Papers: 1.8K
G
Georgina V. Long
H-index: 169 · Papers: 1.8K
J
Johann S. de Bono
H-index: 160 · Papers: 2.5K
C
Caroline Robert
H-index: 154 · Papers: 1.5K
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