Not logged inAn Upstream RUNX3 Enhancer, eR3 (-18m/-28h), Regulates the Development of Gut-Associated Anti-Tumorigenic CD8+CD103+Cytotoxic T Lymphocytes in Mouse and Human
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SaveTargeting transcription factors through an IMiD independent zinc finger domainLiu, Bee Hui; Liu, Miao; Radhakrishnan, Sridhar; Dai, Meng-Yuan; Jaladanki, Chaitanya Kumar; Gao, Chong; Tang, Jing Ping; Kumari, Kalpana; Go, Mei Lin; Vu, Kim Anh L.; Kwon, Junsu; Seo, Hyuk-Soo; Song, Kijun; Tian, Xi; Feng, Li; Tan, Justin L.; Melkonian, Arek, V; Liu, Zhaoji; Wulf, Gerburg; Arthanari, Haribabu; Qi, Jun; Dhe-Paganon, Sirano; Clohessy, John G.; Choong, Yeu Khai; Sivaraman, J.; Fan, Hao; Tenen, Daniel G.; Chai, Li Share Save Chromatin structure and 3D architecture define the differential functions of PU.1 regulatory elements in blood cell lineagesQiu, Kevin; Vu, Duc C.; Wang, Leran; Nguyen, Nicholas N.; Bookstaver, Anna K.; Sol-Church, Katia; Li, Hui; Dinh, Thang N.; Goldfarb, Adam N.; Tenen, Daniel G.; Trinh, Bon Q. Share Save Share Save Extracellular vesicle surface display enhances the therapeutic efficacy and safety profile of cancer immunotherapyJayasinghe, Migara Kavishka; Lay, Yock Sin; Liu, Dawn Xiao Tian; Lee, Chang Yu; Gao, Chang; Yeo, Brendon Zhijie; How, Faith Yuan Xin; Prajogo, Rebecca Carissa; Hoang, Dong Van; Le, Hong Anh; Pham, Thach Tuan; Peng, Boya; Phung, Cao Dai; Tenen, Daniel G.; Le, Minh T. N. Share Save Super-silencer perturbation by EZH2 and REST inhibition leads to large loss of chromatin interactions and reduction in cancer growthZhang, Ying; Chen, Kaijing; Tang, Seng Chuan; Cai, Yichao; Nambu, Akiko; See, Yi Xiang; Fu, Chaoyu; Raju, Anandhkumar; Lebeau, Benjamin; Ling, Zixun; Chan, Jia Jia; Tay, Yvonne; Mutwil, Marek; Lakshmanan, Manikandan; Tucker-Kellogg, Greg; Chng, Wee Joo; Tenen, Daniel G.; Osato, Motomi; Tergaonkar, Vinay; Fullwood, Melissa Jane Share Save Share Save E4F1 and ZNF148 are transcriptional activators of the-57A > C and wild-type TERT promoterChua, Boon Haow; Anuar, Nurkaiyisah Zaal; Ferry, Laure; Domrane, Cecilia; Wittek, Anna; Mukundan, Vineeth T.; Jha, Sudhakar; Butter, Falk; Tenen, Daniel G.; Defossez, Pierre-Antoine; Kappei, Dennis Share Save APOE4 impairs the microglial response in Alzheimer's disease by inducing TGFβ-mediated checkpointsYin, Zhuoran; Rosenzweig, Neta; Kleemann, Kilian L.; Zhang, Xiaoming; Brandao, Wesley; Margeta, Milica A.; Schroeder, Caitlin; Sivanathan, Kisha N.; Silveira, Sebastian; Gauthier, Christian; Mallah, Dania; Pitts, Kristen M.; Durao, Ana; Herron, Shawn; Shorey, Hannah; Cheng, Yiran; Barry, Jen-Li; Krishnan, Rajesh K.; Wakelin, Sam; Rhee, Jared; Yung, Anthony; Aronchik, Michael; Wang, Chao; Jain, Nimansha; Bao, Xin; Gerrits, Emma; Brouwer, Nieske; Deik, Amy; Tenen, Daniel G.; Ikezu, Tsuneya; Santander, Nicolas G.; Mckinsey, Gabriel L.; Baufeld, Caroline; Sheppard, Dean; Krasemann, Susanne; Nowarski, Roni; Eggen, Bart J. L.; Clish, Clary; Tanzi, Rudolph E.; Madore, Charlotte; Arnold, Thomas D.; Holtzman, David M.; Butovsky, Oleg Share Save Dissecting the cell of origin of aberrant SALL4 expression in myelodysplastic syndromeTatetsu, Hiro; Watanabe, Miho; Liu, Jun; Tokunaga, Kenji; Iwanaga, Eisaku; Komohara, Yoshihiro; Thrash, Emily; Bassal, Mahmoud A. A.; Matsuoka, Masao; Tenen, Daniel G. G.; Chai, Li Share Save Share Save Share Save Share Save Share Save Potential autoregulation of transcription factor PU.1 by an upstream reaulatory elementOkuno, Y; Huang, G; Rosenbauer, F; Evans, EK; Radomska, HS; Iwasaki, H; Akashi, K; Moreau-Gachelin, F; Li, YL; Zhang, P; Göttgens, B; Tenen, DG Share Save Share Save Share Save Share Save The Pu.1 locus is differentially regulated at the level of chromatin structure and Noncoding transcription by alternate mechanisms at distinct developmental stages of hematopoiesisHoogenkamp, Maarten; Krysinska, Hanna; Ingram, Richard; Huang, Gang; Barlow, Rachael; Clarke, Deborah; Ebralidze, Alexander; Zhang, Pu; Tagoh, Hiromi; Cockerill, Peter N.; Tenen, Daniel G.; Bonifer, Constanze Share Save Respiratory failure due to differentiation arrest and expansion of alveolar cells following lung-specific loss of the transcription factor C/EBPα in miceBassères, DS; Levantini, E; Ji, HB; Monti, S; Elf, S; Dayaram, T; Fenyus, M; Kocher, O; Golub, T; Wong, KK; Halmos, B; Tenen, DG Share Save 
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