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RGT-61159, Best-in-Class Small Molecule Inhibitor of MYB Via Selective RNA Splicing Alteration, Showed Robust Anti-Tumor Activity across AML Tumor Models Harboring Common Genetic Lesions Lu, Norman; Soulard, Patricia; Kay, Ibrahim; Li, Kai; Gu, Xiubin; Sadlish, Heather; Lee, Jay; Elhawary, Mariam; Rotelli, Michael; Hasson, Sam; Wynn, Thomas; Yates, Chris; Weng, Zhiping; Xi, Simon; Wager, Travis Share Save
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Stricturing Crohn's Disease Single-Cell RNA Sequencing Reveals Fibroblast Heterogeneity and Intercellular Interactions Mukherjee, Pranab K.; Nguyen, Quang Tam; Li, Jiannan; Zhao, Shuai; Christensen, Stephen M.; West, Gail A.; Chandra, Jyotsna; Gordon, Ilyssa O.; Lin, Sinan; Wang, Jie; Mao, Ren; Czarnecki, Douglas; Rayan, Carla; Goren, Idan; Banerjee, Suhanti; Kotak, Prerna; Plesec, Thomas; Lal, Samir; Fabre, Thomas; Asano, Shoh; Bound, Kathryn; Hart, Kevin; Park, Chanyoung; Martinez, Robert; Dower, Ken; Wynn, Thomas A.; Hu, Shaomin; Naydenov, Nayden; Decaris, Martin; Turner, Scott; Holubar, Stefan D.; Steele, Scott R.; Fiocchi, Claudio; Ivanov, Andrei I.; Kravarik, Kellie M.; Rieder, Florian Share Save
Identification of a broadly fibrogenic macrophage subset induced by type 3 inflammation Fabre, Thomas; Barron, Alexander M. S.; Christensen, Stephen M.; Asano, Shoh; Bound, Kathryn; Lech, Matthew P.; Wadsworth, Marc H., II; Chen, Xiao; Wang, Chang; Wang, Ju; McMahon, James; Schlerman, Franklin; White, Alexis; Kravarik, Kellie M.; Fisher, Andrew J.; Borthwick, Lee A.; Hart, Kevin M.; Henderson, Neil C.; Wynn, Thomas A.; Dower, Ken Share Save
Epithelial-intrinsic defects in TGFβR signaling drive local allergic inflammation manifesting as eosinophilic esophagitis Laky, Karen; Kinard, Jessica L.; Li, Jenny Min; Moore, Ian N.; Lack, Justin; Fischer, Elizabeth R.; Kabat, Juraj; Latanich, Rachel; Zachos, Nicholas C.; Limkar, Ajinkya R.; Weissler, Katherine A.; Thompson, Robert W.; Wynn, Thomas A.; Dietz, Harry C.; Guerrerio, Anthony L.; Frischmeyer-Guerrerio, Pamela A. Share Save
Immune responses against SARS-CoV-2 variants after two and three doses of vaccine in B-cell malignancies: UK PROSECO study Lim, Sean H.; Stuart, Beth; Joseph-Pietras, Debora; Johnson, Marina; Campbell, Nicola; Kelly, Adam; Jeffrey, Danielle; Turaj, Anna H.; Rolfvondenbaumen, Kate; Galloway, Celine; Wynn, Thomas; Coleman, Adam R.; Ward, Benjamin; Long, Karen; Coleman, Helen; Mundy, Carina; Bates, Andrew T.; Ayres, Diana; Lown, Robert; Falconer, Janlyn; Brake, Oliver; Batchelor, James; Willimott, Victoria; Al-Naeeb, Anna Bowzyk; Robinson, Lisa; O'Callaghan, Ann; Collins, Graham P.; Menne, Tobias; Faust, Saul N.; Fox, Christopher P.; Ahearne, Matthew; Johnson, Peter W. M.; Davies, Andrew J.; Goldblatt, David Share Save
Single-cell analyses of Crohn's disease tissues reveal intestinal intraepithelial T cells heterogeneity and altered subset distributions Jaeger, Natalia; Gamini, Ramya; Cella, Marina; Schettini, Jorge L.; Bugatti, Mattia; Zhao, Shanrong; Rosadini, Charles V.; Esaulova, Ekaterina; Di Luccia, Blanda; Kinnett, Baylee; Vermi, William; Artyomov, Maxim N.; Wynn, Thomas A.; Xavier, Ramnik J.; Jelinsky, Scott A.; Colonna, Marco Share Save
Regional Differences in Human Biliary Tissues and Corresponding In Vitro-Derived Organoids Rimland, Casey A.; Tilson, Samantha G.; Morell, Carola M.; Tomaz, Rute A.; Lu, Wei-Yu; Adams, Simone E.; Georgakopoulos, Nikitas; Otaizo-Carrasquero, Francisco; Myers, Timothy G.; Ferdinand, John R.; Gieseck, Richard L., III; Sampaziotis, Fotios; Tysoe, Olivia C.; Ross, Alexander; Kraiczy, Judith M.; Wesley, Brandon; Muraro, Daniele; Zilbauer, Matthias; Oniscu, Gabriel C.; Hannan, Nicholas R. F.; Forbes, Stuart J.; Saeb-Parsy, Kourosh; Wynn, Thomas A.; Vallier, Ludovic Share Save
Molecular Magnetic Resonance Imaging of Liver Fibrosis and Fibrogenesis Is Not Altered by Inflammation dos Santos Ferreira, Diego; Arora, Gunisha; Gieseck, Richard L., III; Rotile, Nicholas J.; Waghorn, Philip A.; Tanabe, Kenneth K.; Wynn, Thomas A.; Caravan, Peter; Fuchs, Bryan C. Share Save
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Drug discovery efforts on the RNA protein methyltransferase METTL3/METTL14 Boriack-Sjodin, P. Ann; Gardino, Alexandra K.; Wynn, Thomas A.; Buker, Shane M.; Laidlaw, Monique; Sickmier, E. Allen; Hodous, Brian L.; Case, April W.; Greene-Colozzi, April E.; Copeland, Robert A.; Ribich, Scott Share Save
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Anti-IL-13Rα2 therapy promotes recovery in a murine model of inflammatory bowel disease Karmele, Erik P.; Pasricha, Trisha S.; Ramalingam, Thirumalai R.; Thompson, Robert W.; Gieseck, Richard L., III; Knilans, Kayla J.; Hegen, Martin; Farmer, Mark; Jin, Fang; Kleinman, Aaron; Hinds, David A.; Pereira, Thiago Almeida; Prado, Rafael de Queiroz; Bing, Nan; Tchistiakova, Lioudmila; Kasaian, Marion T.; Wynn, Thomas A.; Vannella, Kevin M.; Agee, Michelle; Alipanahi, Babak; Auton, Adam; Bell, Robert K.; Bryc, Katarzyna; Elson, Sarah L.; Fontanillas, Pierre; Furlotte, Nicholas A.; Huber, Karen E.; Litterman, Nadia K.; McIntyre, Matthew H.; Mountain, Joanna L.; Noblin, Elizabeth S.; Northover, Carrie A. M.; Pitts, Steven J.; Sathirapongsasuti, J. Fah; Sazonova, Olga, V; Shelton, Janie F.; Shringarpure, Suyash; Tian, Chao; Tung, Joyce Y.; Vacic, Vladimir; Wilson, Catherine H. Share Save
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Fibroblast-specific integrin-alpha V differentially regulates type 17 and type 2 driven inflammation and fibrosis Sciurba, Joshua C.; Gieseck, Richard L.; Jiwrajka, Nikhil; White, Sandra D.; Karmele, Erik P.; Redes, Jamie; Vannella, Kevin M.; Henderson, Neil C.; Wynn, Thomas A.; Hart, Kevin M. Share Save
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