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Marine sponge microbe provides insights into evolution and virulence of the tubercle bacillus Pidot, Sacha J.; Klatt, Stephan; Ates, Louis S.; Frigui, Wafa; Sayes, Fadel; Majlessi, Laleh; Izumi, Hiroshi; Monk, Ian R.; Porter, Jessica L.; Bennett-Wood, Vicki; Seemann, Torsten; Otter, Ashley; Taiaroa, George; Cook, Gregory M.; West, Nicholas; Tobias, Nicholas J.; Fuerst, John A.; Stutz, Michael D.; Pellegrini, Marc; McConville, Malcolm; Brosch, Roland; Stinear, Timothy P. Share Save
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Natural mutations in the sensor kinase of the PhoPR two-component regulatory system modulate virulence of ancestor-like tuberculosis bacilli Malaga, Wladimir; Payros, Delphine; Meunier, Eva; Frigui, Wafa; Sayes, Fadel; Pawlik, Alexandre; Orgeur, Mickael; Berrone, Celine; Moreau, Flavie; Mazeres, Serge; Gonzalo-Asensio, Jesus; Rengel, David; Martin, Carlos; Astarie-Dequeker, Catherine; Mourey, Lionel; Brosch, Roland; Guilhot, Christophe Share Save
A comprehensive update to the Mycobacterium tuberculosis H37Rv reference genome (vol 13, 7068, 2022) Chitale, Poonam; Lemenze, Alexander D.; Fogarty, Emily C.; Shah, Avi; Grady, Courtney; Odom-Mabey, Aubrey R.; Johnson, W. Evan; Yang, Jason H.; Eren, A. Murat; Brosch, Roland; Kumar, Pradeep; Alland, David Share Save
A comprehensive update to the Mycobacterium tuberculosis H37Rv reference genome Chitale, Poonam; Lemenze, Alexander D.; Fogarty, Emily C.; Shah, Avi; Grady, Courtney; Odom-Mabey, Aubrey R.; Johnson, W. Evan; Yang, Jason H.; Eren, A. Murat; Brosch, Roland; Kumar, Pradeep; Alland, David Share Save
A lentiviral vector expressing a dendritic cell-targeting multimer induces mucosal anti-mycobacterial CD4+ T-cell immunity Anna, Francois; Lopez, Jodie; Moncoq, Fanny; Blanc, Catherine; Authie, Pierre; Noirat, Amandine; Fert, Ingrid; Souque, Philippe; Nevo, Fabien; Pawlik, Alexandre; Hardy, David; Goyard, Sophie; Hudrisier, Denis; Brosch, Roland; Guinet, Francoise; Neyrolles, Olivier; Charneau, Pierre; Majlessi, Laleh Share Save
A lentiviral vector encoding fusion of light invariant chain and mycobacterial antigens induces protective CD4+ T cell immunity Lopez, Jodie; Anna, Francois; Authie, Pierre; Pawlik, Alexandre; Ku, Min-Wen; Blanc, Catherine; Souque, Philippe; Moncoq, Fanny; Noirat, Amandine; Hardy, David; Sougakoff, Wladimir; Brosch, Roland; Guinet, Francoise; Charneau, Pierre; Majlessi, Laleh Share Save
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The Mycobacterium tuberculosis PhoPR virulence system regulates expression of the universal second messenger c-di-AMP and impacts vaccine safety and efficacy Perez, Irene; Campos-Pardos, Elena; Diaz, Caridad; Uranga, Santiago; Sayes, Fadel; Vicente, Francisca; Aguilo, Nacho; Brosch, Roland; Martin, Carlos; Gonzalo-Asensio, Jesus Share Save
IL-1R1-Dependent Signals Improve Control of Cytosolic Virulent Mycobacteria In Vivo van der Niet, Sanne; van Zon, Maaike; de Punder, Karin; Grootemaat, Anita; Rutten, Sofie; Moorlag, Simone J. C. F. M.; Houben, Diane; van der Sar, Astrid M.; Bitter, Wilbert; Brosch, Roland; Pando, Rogelio Hernandez; Pena, Maria T.; Peters, Peter J.; Reits, Eric A.; Mayer-Barber, Katrin D.; van der Wel, Nicole N. Share Save
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Pathogenomic analyses of Mycobacterium microti, an ESX-1-deleted member of the Mycobacterium tuberculosis complex causing disease in various hosts Orgeur, Mickael; Frigui, Wafa; Pawlik, Alexandre; Clark, Simon; Williams, Ann; Ates, Louis S.; Ma, Laurence; Bouchier, Christiane; Parkhill, Julian; Brodin, Priscille; Brosch, Roland Share Save
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Mucosal delivery of ESX-1-expressing BCG strains provides superior immunity against tuberculosis in murine type 2 diabetes Sathkumara, Harindra D.; Muruganandah, Visai; Cooper, Martha M.; Field, Matt A.; Alim, Md Abdul; Brosch, Roland; Ketheesan, Natkunam; Govan, Brenda; Rush, Catherine M.; Henning, Lars; Kupz, Andreas Share Save
The antibiotic bedaquiline activates host macrophage innate immune resistance to bacterial infection Giraud-Gatineau, Alexandre; Coya, Juan Manuel; Maure, Alexandra; Biton, Anne; Thomson, Michael; Bernard, Elliott M.; Marrec, Jade; Gutierrez, Maximiliano G.; Larrouy-Maumus, Gerald; Brosch, Roland; Gicquel, Brigitte; Tailleux, Ludovic Share Save
Live attenuated TB vaccines representing the three modern Mycobacterium tuberculosis lineages reveal that the Euro-American genetic background confers optimal vaccine potential Perez, Irene; Uranga, Santiago; Sayes, Fadel; Frigui, Wafa; Samper, Sofia; Arbues, Ainhoa; Aguilo, Nacho; Brosch, Roland; Martin, Carlos; Gonzalo-Asensio, Us Share Save
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