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M

Michael D. Hogarty

children's hospital of philadelphia

58H-index
273Paper Count
1.8WCitation Count
Published Papers 89
Publication Date
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Publisher Correction: Polyamine-dependent metabolic shielding regulates alternative splicing
errNature
IF48.5
err2026-01-21
err0
errOAAI
errAmaia Zabala-Letona; Mikel Pujana-Vaquerizo; Belen Martinez-Laosa; Maria Ponce-Rodriguez; Saioa Garcia-Longarte; Isabel Mendizabal; Ana Gimeno; Malgorzata Rogalska; Joycelyn Tan; Diana Cabrera; Sebastiaan van Liempd; Pilar Ximenez-Embun; Sergio Espinosa; Maider Fagoaga-Eugui; Francesca Peccati; Maciej Zakrzewski; Ianire Astobiza; Mikel Arana-Castañares; Sarah Cherkaoui; Maria Sendino; Inés Martín-Barros; Amaia Ercilla; Laura Bozal-Basterra; Onintza Carlevaris; Amaia Arruabarrena-Aristorena; Encarnación Pérez-Andrés; Telmo Santamaría-Zamorano; Juan A. Ferrer-Bonsoms; Fernando Carazo; Maciej Cieśla; Cesar Lobato; Joan Seoane; Natalia Martín-Martín; Rosa Barrio; James D. Sutherland; Ana M. Aransay; Juan Manuel Falcón-Pérez; Barbara Martínez-Pastor; Angel Rubio; Francisco J. Blanco; Michael D. Hogarty; Raphael J. Morscher; Edurne Berra; Remigiusz A. Serwa; Jesús Jiménez-Barbero; Gonzalo Jiménez-Osés; Alejo Efeyan; Lydia Finley; Jose M. Lizcano; Javier Muñoz; Juan Valcarcel; Arkaitz Carracedo
errShare
errSave
Polyamine-dependent metabolic shielding regulates alternative splicing
errNature
IF48.5
err2026-01-14
err0
errOAAI
errAmaia Zabala-Letona; Mikel Pujana-Vaquerizo; Belen Martinez-Laosa; Maria Ponce-Rodriguez; Saioa Garcia-Longarte; Isabel Mendizabal; Ana Gimeno; Malgorzata Rogalska; Joycelyn Tan; Diana Cabrera; Sebastiaan van Liempd; Pilar Ximenez-Embun; Sergio Espinosa; Maider Fagoaga-Eugui; Francesca Peccati; Maciej Zakrzewski; Ianire Astobiza; Mikel Arana-Castañares; Sarah Cherkaoui; Maria Sendino; Inés Martín-Barros; Amaia Ercilla; Laura Bozal-Basterra; Onintza Carlevaris; Amaia Arruabarrena-Aristorena; Encarnación Pérez-Andrés; Telmo Santamaría-Zamorano; Juan A. Ferrer-Bonsoms; Fernando Carazo; Maciej Cieśla; Cesar Lobato; Joan Seoane; Natalia Martín-Martín; Rosa Barrio; James D. Sutherland; Ana M. Aransay; Juan Manuel Falcón-Pérez; Barbara Martínez-Pastor; Angel Rubio; Francisco J. Blanco; Michael D. Hogarty; Raphael J. Morscher; Edurne Berra; Remigiusz A. Serwa; Jesús Jiménez-Barbero; Gonzalo Jiménez-Osés; Alejo Efeyan; Lydia Finley; Jose M. Lizcano; Javier Muñoz; Juan Valcarcel; Arkaitz Carracedo
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errSave
Reprogramming neuroblastoma by diet-enhanced polyamine depletion
errNature
IF48.5
err2025-09-24
err0
errOAAI
errSarah Cherkaoui; Christina S. Turn; Yuan Yuan; Wenyun Lu; Lifeng Yang; Matthew J. McBride; Caroline Eigenmann; George E. Allen; Olesya O. Panasenko; Lu Zhang; Annette Vu; Kangning Liu; Yimei Li; Om H. Gandhi; Lea F. Surrey; Sandra D. Kienast; Sebastian A. Leidel; Michael Wierer; Eileen White; Joshua D. Rabinowitz; Michael D. Hogarty; Raphael J. Morscher
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errSave
High-dose DFMO alters protein translation in neuroblastoma
errNeoplasia
IF7.7
err2025-08-06
err0
PREAI
errAndrea T. Franson; Kangning Liu; Rohan Vemu; Elizabeth Scadden; Yimei Li; Annette Vu; Michael D. Hogarty
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errSave
Longitudinal single-cell multiomic atlas of high-risk neuroblastoma reveals chemotherapy-induced tumor microenvironment rewiring
errNATURE GENETICS
IF0
err2025-04-14
err0
errOAAI
errYu, Wenbao; Biyik-Sit, Rumeysa; Uzun, Yasin; Chen, Chia-Hui; Thadi, Anusha; Sussman, Jonathan H.; Pang, Minxing; Wu, Chi-Yun; Grossmann, Liron D.; Gao, Peng; Wu, David W.; Yousey, Aliza; Zhang, Mei; Turn, Christina S.; Zhang, Zhan; Bandyopadhyay, Shovik; Huang, Jeffrey; Patel, Tasleema; Chen, Changya; Martinez, Daniel; Surrey, Lea F.; Hogarty, Michael D.; Bernt, Kathrin; Zhang, Nancy R.; Maris, John M.; Tan, Kai
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Response of neuroblastoma patient-derived xenografts to cyclophosphamide plus topotecan enables identification of gene expression patterns associated with drug resistance
errCANCER RESEARCH
IF16.6
err2024-09-05
err0
PREAI
errNoureen, Nighat; May, Harry; Yang, In-Hyoung; McCoy, Kristyn; Nance, Jonas; Ixlamati-Nava, Diana; Irwin, Meredith S.; Hogarty, Michael D.; Reynolds, Charles P.; Kang, Min H.
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VCAN plus macrophages promote neuroblastoma cell growth, migration, and adrenergic to mesenchymal transition via the HB-EGF/ERBB signaling axis
errCANCER RESEARCH
IF16.6
err2024-09-05
err0
PREAI
errBiyik-Sit, Rumeysa; Yu, Wenbao; Chen, Chia-Hui; Thadi, Anusha; Pang, Minxing; Grossmann, Liron D.; Patel, Tasleema; Martinez, Daniel; Surrey, Lea F.; Hogarty, Michael D.; Bernt, Kathrin; Zhang, Nancy; Maris, John M.; Tan, Kai
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errSave
Langerhans cell histiocytosis: NACHO update on progress, chaos, and opportunity on the path to rational cures
errCANCER
IF5.1
err2024-04-30
err1
PREAI
errBielamowicz, Kevin; Dimitrion, Peter; Abla, Oussama; Bomken, Simon; Campbell, Patrick; Collin, Matthew; Degar, Barbara; Diamond, Eli L.; Eckstein, Olive S.; El-Mallawany, Nader; Fluchel, Mark; Goyal, Gaurav; Henry, Michael M.; Hermiston, Michelle; Hogarty, Michael; Jeng, Michael; Jubran, Rima; Lubega, Joseph; Kumar, Ashish; Ladisch, Stephan; McClain, Kenneth L.; Merad, Miriam; Mi, Qing-Sheng; Parsons, D. Williams; Peckham-Gregory, Erin; Picarsic, Jennifer; Prudowsky, Zachary D.; Rollins, Barrett J.; Shaw, Peter H.; Wistinghausen, Birte; Rodriguez-Galindo, Carlos; Allen, Carl E.
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errSave
Modulating anti-GD2 immunotherapy via dual DFMO and TGF-β inhibition in neuroblastoma
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errGandhi, Om H.; Turn, Christina S.; Liu, Kangning; Vu, Annette T.; Bassiri, Hamid; Hogarty, Michael D.
errShare
errSave
Phase 1 study of high-dose DFMO, celecoxib, cyclophosphamide and topotecan for patients with relapsed neuroblastoma: a New Approaches to Neuroblastoma Therapy trial
errBRITISH JOURNAL OF CANCER
IF6.8
err2024-01-10
err5
errOAAI
errHogarty, Michael D.; Ziegler, David S.; Franson, Andrea; Chi, Yueh-Yun; Tsao-Wei, Denice; Liu, Kangning; Vemu, Rohan; Gerner, Eugene W.; Bruckheimer, Elizabeth; Shamirian, Anasheh; Hasenauer, Beth; Balis, Frank M.; Groshen, Susan; Norris, Murray D.; Haber, Michelle; Park, Julie R.; Matthay, Katherine K.; Marachelian, Araz
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Addition of AMXT1501 (polyamine uptake inhibitor) plus DFMO (polyamine synthesis inhibitor) to standard-of-care chemotherapy/anti-GD2 antibody in the TH-MYCN mouse neuroblastoma model, enhances efficacy compared to addition of DFMO alone
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2023-12-01
err0
PREAI
errMurray, Jayne; Pandher, Ruby; Xiao, Lin; Somers, Klaartje; Brand, Jennifer; Mosmann, Erin; Alfred, Stephanie; Kusuma, Frances; Keams, Adam; Park, Julie R.; Marshall, Lynley V.; Gorrini, Chiara; Chesler, Louis; Hogarty, Michael D.; Pearson, Andrew D. J.; Burns, Mark; Fletcher, Jamie I.; Ziegler, David; Norris, Murray D.; Haber, Michelle
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errSave
Mitoribosomal synthetic lethality overcomes multidrug resistance in MYC-driven neuroblastoma
errCELL DEATH & DISEASE
IF9.6
err2023-11-16
err4
errOAAI
errBorankova, Karolina; Krchniakova, Maria; Leck, Lionel Y. W.; Kubistova, Adela; Neradil, Jakub; Jansson, Patric J.; Hogarty, Michael D.; Skoda, Jan
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errSave
Impact of Genomic and Clinical Factors on Outcome of Children?18 Months of Age with Stage 3 Neuroblastoma with Unfavorable Histology and without MYCN Amplification: A Children?s Oncology Group (COG) Report
errCLINICAL CANCER RESEARCH
IF10.2
err2023-02-07
err9
errOAAI
errPinto, Navin; Naranjo, Arlene; Ding, Xiangming; Zhang, Fan F.; Hibbitts, Emily; Kennedy, Rebekah; Tibbetts, Rachelle; Wong-Michalak, Shannon; Craig, David W.; Manojlovic, Zarko; Hogarty, Michael D.; Kreissman, Susan; Bagatell, Rochelle; Irwin, Meredith S.; Park, Julie R.; Asgharzadeh, Shahab
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errSave
TH-MYCN tumors, but not tumor-derived cell lines, are adrenergic lineage, GD2+, and responsive to anti-GD2 antibody therapy
errONCOIMMUNOLOGY
IF6.3
err2022-05-24
err9
errOAAI
errMcNerney, K. O.; Karageorgos, S.; Ferry, G. M.; Wolpaw, A. J.; Burudpakdee, C.; Khurana, P.; Toland, C. N.; Vemu, R.; Vu, A.; Hogarty, M. D.; Bassiri, H.
errShare
errSave
Reduced ER-mitochondria connectivity promotes neuroblastoma multidrug resistance
errEMBO JOURNAL
IF8.3
err2022-02-25
err16
errOAAI
errCoku, Jorida; Booth, David M.; Skoda, Jan; Pedrotty, Madison C.; Vogel, Jennifer; Liu, Kangning; Vu, Annette; Carpenter, Erica L.; Ye, Jamie C.; Chen, Michelle A.; Dunbar, Peter; Scadden, Elizabeth; Yun, Taekyung D.; Nakamaru-Ogiso, Eiko; Area-Gomez, Estela; Li, Yimei; Goldsmith, Kelly C.; Reynolds, C. Patrick; Hajnoczky, Gyorgy; Hogarty, Michael D.
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errSave
Epigenetic state determines inflammatory sensing in neuroblastoma
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2022-02-04
err28
errOAAI
errWolpaw, Adam J.; Grossmann, Liron D.; Dessau, Jessica L.; Dong, May M.; Aaron, Bailey J.; Brafford, Patricia A.; Volgina, Darya; Pascual-Pasto, Guillem; Rodriguez-Garcia, Alba; Uzun, Yasin; Arsenian-Henriksson, Marie; Powell, Daniel J., Jr.; Bosse, Kristopher R.; Kossenkov, Andrew; Tan, Kai; Hogarty, Michael D.; Maris, John M.; Dang, Chi V.
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errSave
Histiocytic Neoplasms, Version 2.2021
errJOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK
IF16.4
err2021-11-01
err34
errOAAI
errGo, Ronald S.; Jacobsen, Eric; Baiocchi, Robert; Buhtoiarov, Ilia; Butler, Erin B.; Campbell, Patrick K.; Coulter, Don W.; Diamond, Eli; Flagg, Aron; Goodman, Aaron M.; Goyal, Gaurav; Gratzinger, Dita; Hendrie, Paul C.; Higman, Meghan; Hogarty, Michael D.; Janku, Filip; Karmali, Reem; Morgan, David; Raldow, Anne C.; Stefanovic, Alexandra; Tantravahi, Srinivas K.; Walkovich, Kelly; Zhang, Ling; Bergman, Mary Anne; Darlow, Susan D.
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errSave
MYCN-induced nucleolar stress drives an early senescence-like transcriptional program in hTERT-immortalized RPE cells
errSCIENTIFIC REPORTS
IF3.9
err2021-07-14
err8
errOAAI
errZanotti, Sofia; Vanhauwaert, Suzanne; Van Neste, Christophe; Olexiouk, Volodimir; Van Laere, Jolien; Verschuuren, Marlies; Van der Meulen, Joni; Mus, Liselot M.; Durinck, Kaat; Tilleman, Laurentijn; Deforce, Dieter; Van Nieuwerburgh, Filip; Hogarty, Michael D.; Decaesteker, Bieke; De Vos, Winnok H.; Speleman, Frank
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errSave
Myeloablative Busulfan/Melphalan Consolidation following Induction Chemotherapy for Patients with Newly Diagnosed High-Risk Neuroblastoma: Children's Oncology Group Trial ANBL12P1
errTRANSPLANTATION AND CELLULAR THERAPY
IF4.4
err2021-06-01
err20
errOAAI
errGranger, M. Meaghan; Naranjo, Arlene; Bagatell, Rochelle; DuBois, Steven G.; McCune, Jeannine S.; Tenney, Sheena C.; Weiss, Brian D.; Mosse, Yael P.; Asgharzadeh, Shahab; Grupp, Stephen A.; Hogarty, Michael D.; Gastier-Foster, Julie M.; Mills, Denise; Shulkin, Barry L.; Parisi, Marguerite T.; London, Wendy B.; Han-Chang, John; Panoff, Joseph; von Allmen, Daniel; Jarzembowski, Jason A.; Park, Julie R.; Yanik, Gregory A.
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Preclinical assessment of the efficacy and specificity of GD2-B7H3 SynNotch CAR-T in metastatic neuroblastoma
errNATURE COMMUNICATIONS
IF15.7
err2021-01-21
err110
errOAAI
errMoghimi, Babak; Muthugounder, Sakunthala; Jambon, Samy; Tibbetts, Rachelle; Hung, Long; Bassiri, Hamid; Hogarty, Michael D.; Barrett, David M.; Shimada, Hiroyuki; Asgharzadeh, Shahab
errShare
errSave

Research Directions

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Co-authors
Cooperation Journals
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Gad Getz
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Matthew Meyerson
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Ralph H. Hruban
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