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A pH-sensitive opioid does not exhibit analgesic tolerance in a mouse model of colonic inflammation Degro, Claudius E.; Jimenez-Vargas, Nestor Nivardo; Guzman-Rodriguez, Mabel; Schincariol, Hailey; Tsang, Quentin; Reed, David E.; Lomax, Alan E.; Bunnett, Nigel W.; Stein, Christoph; Vanner, Stephen J. Share Save
Characterizing genetic profiles for high triglyceride levels in US patients of African ancestry Jiang, Lan; Gangireddy, Srushti; Dickson, Alyson L.; Xin, Yi; Yan, Chao; Kawai, Vivian; Cox, Nancy J.; Linton, MacRae F.; Wei, Wei-Qi; Stein, C. Michael; Feng, QiPing Share Save
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Clinical associations with a polygenic predisposition to benign lower white blood cell counts Mosley, Jonathan D.; Shelley, John P.; Dickson, Alyson L.; Zanussi, Jacy; Daniel, Laura L.; Zheng, Neil S.; Bastarache, Lisa; Wei, Wei-Qi; Shi, Mingjian; Jarvik, Gail P.; Rosenthal, Elisabeth A.; Khan, Atlas; Sherafati, Alborz; Kullo, Iftikhar J.; Walunas, Theresa L.; Glessner, Joseph; Hakonarson, Hakon; Cox, Nancy J.; Roden, Dan M.; Frangakis, Stephan G.; Vanderwerff, Brett; Stein, C. Michael; Van Driest, Sara L.; Borinstein, Scott C.; Shu, Xiao-Ou; Zawistowski, Matthew; Chung, Cecilia P.; Kawai, Vivian K. Share Save
Leveraging generative AI to prioritize drug repurposing candidates for Alzheimer's disease with real-world clinical validation Yan, Chao; Grabowska, Monika E.; Dickson, Alyson L.; Li, Bingshan; Wen, Zhexing; Roden, Dan M.; Stein, C. Michael; Embi, Peter J.; Peterson, Josh F.; Feng, Qiping; Malin, Bradley A.; Wei, Wei-Qi Share Save
Concurrent Gabapentin and Opioid Use and Risk of Mortality in Medicare Recipients with Non-Cancer Pain Corriere, Meghan A.; Daniel, Laura L.; Dickson, Alyson L.; Nepal, Puran; Hall, Kathi; Plummer, W. Dale; Dupont, William D.; Murray, Katherine T.; Stein, C. Michael; Ray, Wayne A.; Chung, Cecilia P. Share Save
Evolving acidic microenvironments during colitis provide selective analgesic targets for a pH-sensitive opioid Degro, Claudius E.; Jimenez-Vargas, Nestor Nivardo; Tsang, Quentin; Yu, Yang; Guzman-Rodriguez, Mabel; Alizadeh, Elahe; Hurlbut, David; Reed, David E.; Lomax, Alan E.; Stein, Christoph; Bunnett, Nigel W.; Vanner, Stephen J. Share Save
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Modelling altered signalling of G-protein coupled receptors in inflamed environment to advance drug design Thies, Arne; Sunkara, Vikram; Ray, Sourav; Wulkow, Hanna; Celik, M. Oezguer; Yergoez, Fatih; Schuette, Christof; Stein, Christoph; Weber, Marcus; Winkelmann, Stefanie Share Save
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Phenome-Wide Association Study of UMOD Gene Variants and Differential Associations With Clinical Outcomes Across Populations in the Million Veteran Program a Multiethnic Biobank Akwo, Elvis A.; Chen, Hua-Chang; Liu, Ge; Triozzi, Jefferson L.; Tao, Ran; Yu, Zhihong; Chung, Cecilia P.; Giri, Ayush; Ikizler, T. Alp; Stein, C. Michael; Siew, Edward D.; Feng, QiPing; Robinson-Cohen, Cassianne; Hung, Adriana M.; VA Million Veteran Program, behalf of the V. A. Million Veteran Program Share Save
Race, Genotype, and Azathioprine Discontinuation A Cohort Study Dickson, Alyson L.; Daniel, Laura L.; Jackson, Elise; Zanussi, Jacy; Yang, Wenjian; Plummer, W. Dale; Dupont, William D.; Wei, Wei-Qi; Nepal, Puran; Hung, Adriana M.; Cox, Nancy J.; Van Driest, Sara L.; Feng, QiPing; Yang, Jun J.; Stein, C. Michael; Mosley, Jonathan D.; Chung, Cecilia P. Share Save
Isolevuglandins disrupt PU.1-mediated C1q expression and promote autoimmunity and hypertension in systemic lupus erythematosus Patrick, David M.; Visitacion, Nestor de la; Krishnan, Jaya; Chen, Wei; Ormseth, Michelle J.; Stein, C. Michael; Davies, Sean S.; Amarnath, Venkataraman; Crofford, Leslie J.; Williams, Jonathan M.; Zhao, Shilin; Smart, Charles D.; Dikalov, Sergey; Dikalova, Anna; Xiao, Liang; Van Beusecum, Justin P.; Ao, Mingfang; Fogo, Agnes B.; Kirabo, Annet; Harrison, David G. Share Save
Predicted expression of genes involved in the thiopurine metabolic pathway and azathioprine discontinuation due to myelotoxicity Daniel, Laura L.; Dickson, Alyson L.; Zanussi, Jacy T.; Miller-Fleming, Tyne W.; Straub, Peter S.; Wei, Wei-Qi; Plummer, W. Dale; Dupont, William D.; Liu, Ge; Anandi, Prathima; Reese, Tyler S.; Birdwell, Kelly A.; Kawai, Vivian K.; Hung, Adriana M.; Cox, Nancy J.; Feng, QiPing; Stein, C. Michael; Chung, Cecilia P. Share Save