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Lessons learned from a candidate gene study investigating aromatase inhibitor treatment outcome in breast cancer Hoppe, Reiner; Winter, Stefan; Lo, Wing-Yee; Michailidou, Kyriaki; Bolla, Manjeet K.; Keeman, Renske; Wang, Qin; Dennis, Joe; Lush, Michael; Kalari, Krishna R.; Goetz, Matthew P.; Wang, Liewei; Cairns, Junmei; Weinshilboum, Richard; Shepherd, Lois; Chen, Bingshu E.; Haeberle, Lothar; Ruebner, Matthias; Beckmann, Matthias W.; He, Wei; Larson, Nicole L.; Armasu, Sebastian M.; Schroth, Werner; Chowbay, Balram; Khor, Chiea Chuen; Abubakar, Mustapha; Antoniou, Antonis C.; Bruening, Thomas; Castelao, Jose E.; Chang-Claude, Jenny; Doerk, Thilo; Eccles, Diana M.; Figueroa, Jonine D.; Gago-Dominguez, Manuela; Garcia-Saenz, Jose A.; Guendert, Melanie; Hack, Carolin C.; Hamann, Ute; Han, Sileny; Hooning, Maartje J.; Huebner, Hanna; John, Esther M.; Ko, Yon-Dschun; Kristensen, Vessela N.; Linn, Sabine; Margolin, Sara; Mavroudis, Dimitrios; Nevanlinna, Heli; Neven, Patrick; Obi, Nadia; Park-Simon, Tjoung-Won; Pylkaes, Katri; Rashid, Muhammad U.; Romero, Atocha; Saloustros, Emmanouil; Sawyer, Elinor J.; Tapper, William J.; Tomlinson, Ian; Wendt, Camilla; Winqvist, Robert; Dunning, Alison M.; Simard, Jacques; Hall, Per; Pharoah, Paul D. P.; Schwab, Matthias; Couch, Fergus J.; Czene, Kamila; Fasching, Peter A.; Easton, Douglas F.; Schmidt, Marjanka K.; Ingle, James N.; Brauch, Hiltrud Share Save
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mitoBKCa is functionally expressed in murine and human breast cancer cells and potentially contributes to metabolic reprogramming Bischof, Helmut; Maier, Selina; Koprowski, Piotr; Kulawiak, Bogusz; Burgstaller, Sandra; Jasinska, Joanna; Serafimov, Kristian; Zochowska, Monika; Gross, Dominic; Schroth, Werner; Matt, Lucas; Juarez Lopez, David Arturo; Zhang, Ying; Bonzheim, Irina; Buettner, Florian A.; Fend, Falko; Schwab, Matthias; Birkenfeld, Andreas L.; Malli, Roland; Laemmerhofer, Michael; Bednarczyk, Piotr; Szewczyk, Adam; Lukowski, Robert Share Save
Nonlinear Mixed-Effects Model of Z-Endoxifen Concentrations in Tamoxifen-Treated Patients from the CEPAM Cohort McLaughlin, Anna M.; Helland, Thomas; Klima, Fenja; Koolen, Stijn L. W.; van Schaik, Ron H. N.; Mathijssen, Ron H. J.; Neven, Patrick; Swen, Jesse J.; Guchelaar, Henk-Jan; Dalenc, Florence; White-Koning, Melanie; Michelet, Robin; Mikus, Gerd; Schroth, Werner; Muerdter, Thomas; Brauch, Hiltrud; Schwab, Matthias; Soiland, Havard; Mellgren, Gunnar; Thomas, Fabienne; Kloft, Charlotte; Hertz, Daniel L. Share Save
Cross-Ancestry Genome-Wide Association Study Defines the Extended CYP2D6 Locus as the Principal Genetic Determinant of Endoxifen Plasma Concentrations Khor, Chiea Chuen; Winter, Stefan; Sutiman, Natalia; Muerdter, Thomas E.; Chen, Sylvia; Lim, Joanne Siok Liu; Li, Zheng; Li, Jingmei; Sim, Kar Seng; Ganchev, Boian; Eccles, Diana; Eccles, Bryony; Tapper, William; Zgheib, Nathalie K. K.; Tfayli, Arafat; Ng, Raymond Chee Hui; Yap, Yoon Sim; Lim, Elaine; Wong, Mabel; Wong, Nan Soon; Ang, Peter Cher Siang; Dent, Rebecca; Tremmel, Roman; Klein, Kathrin; Schaeffeler, Elke; Zhou, Yitian; Lauschke, Volker M. M.; Eichelbaum, Michel; Schwab, Matthias; Brauch, Hiltrud B. B.; Chowbay, Balram; Schroth, Werner Share Save
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(Z)-Endoxifen and Early Recurrence of Breast Cancer: An Explorative Analysis in a Prospective Brazilian Study Almeida, Thais; Schroth, Werner; Nardin, Jeanine; Murdter, Thomas E.; Winter, Stefan; Picolotto, Solane; Hoppe, Reiner; Kogin, Jenifer; Gaio, Elisa; Dasenbrock, Angela; Skrsypcsak, Raquel Cristina; de Noronha, Lucia; Schwab, Matthias; Brauch, Hiltrud; Casali-da-Rocha, Jose Claudio Share Save
Endoxifen predicts early recurrence in breast cancer: A Brazilian prospective study Almeida, Thais; Schroth, Werner; Nardin, Jeanine Marie; Murdter, Thomas; Picolotto, Solane; Hoppe, Reiner; Kogin, Jenifer Primon; Gaio, Elisa Daniele; Dasenbrock, Angela; Skrsypcsak, Raquel Cristina; Noronha, Lucia; Brauch, Hiltrud; Casali-da-Rocha, Jose Claudio Share Save
Subunits of BK channels promote breast cancer development and modulate responses to endocrine treatment in preclinical models Mohr, Corinna J.; Schroth, Werner; Muerdter, Thomas E.; Gross, Dominic; Maier, Selina; Stegen, Benjamin; Dragoi, Alice; Steudel, Friederike A.; Stehling, Severine; Hoppe, Reiner; Madden, Stephen; Ruth, Peter; Huber, Stephan M.; Brauch, Hiltrud; Lukowski, Robert Share Save
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Obesity Alters Endoxifen Plasma Levels in Young Breast Cancer Patients: A Pharmacometric Simulation Approach Mueller-Schoell, Anna; Klopp-Schulze, Lena; Schroth, Werner; Muerdter, Thomas; Michelet, Robin; Brauch, Hiltrud; Huisinga, Wilhelm; Joerger, Markus; Neven, Patrick; Koolen, Stijn L. W.; Mathijssen, Ron H. J.; Copson, Ellen; Eccles, Diana; Chen, Sylvia; Chowbay, Balram; Tfayli, Arafat; Zgheib, Nathalie K.; Schwab, Matthias; Kloft, Charlotte Share Save
The influences of adherence to tamoxifen and CYP2D6 pharmacogenetics on plasma concentrations of the active metabolite (Z)-endoxifen in breast cancer Casali da Rocha, Jose Claudio; Nardin, Jeanine M.; Schroth, Werner; Almeida, Thais A.; Muerdter, Thomas; Picolotto, Solange; Vendramini, Evelyn C. L.; Hoppe, Reiner; Kogin, Jenifer P.; Miqueleto, Diandra; Moraes, Silvia D. R.; Schwab, Matthias; Pecoits-Filho, Roberto F.; Brauch, Hiltrud Share Save
The Influences of Adherence to Tamoxifen and CYP2D6 Pharmacogenetics on Plasma Concentrations of the Active Metabolite (Z)-Endoxifen in Breast Cancer Nardin, Jeanine Marie; Schroth, Werner; Almeida, Thais Abreu; Muerdter, Thomas; Picolotto, Solane; Lima Vendramini, Evelyn Castillo; Hoppe, Reiner; Kogin, Jenifer Primon; Miqueleto, Diandra; Robaskievicz de Moraes, Silvia Dark; Schwab, Matthias; Pecoits-Filho, Roberto Flavio; Brauch, Hiltrud; Casali-da-Rocha, Jose Claudio Share Save
Gene expression signatures for the prediction of endocrine treatment outcome in early-stage luminal breast cancer patients Schroth, Werner; Hoppe, Reiner; Buettner, Florian; Winter, Stefan; Kandabarau, Siarhei; Kumbrink, Joerg; Brauer, Heather A.; Fritz, Peter; Schwab, Matthias; Muerdter, Thomas; Brauch, Hiltrud Share Save
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The formation of estrogen-like tamoxifen metabolites and their influence on enzyme activity and gene expression of ADME genes Johaenning, Janina; Kroener, Patrick; Thomas, Maria; Zanger, Ulrich M.; Noerenberg, Astrid; Eichelbaum, Michel; Schwab, Matthias; Brauch, Hiltrud; Schroth, Werner; Muerdter, Thomas E. Share Save
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SK4 channels modulate Ca2+ signalling and cell cycle progression in murine breast cancer Steudel, Friederike A.; Mohr, Corinna J.; Stegen, Benjamin; Nguyen, Hoang Y.; Barnert, Andrea; Steinle, Marc; Beer-Hammer, Sandra; Koch, Pierre; Lo, Wing-Yee; Schroth, Werner; Hoppe, Reiner; Brauch, Hiltrud; Ruth, Peter; Huber, Stephan M.; Lukowski, Robert Share Save
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