Not logged in Drug-tolerant persisting polyploid giant cancer cells mediate resistance to HER2-targeting antibody-drug conjugates Yazdi, Narjes; Pourjamal, Negar; Katainen, Riku; Vaananen, Juho; Dai, Jun; Vaharautio, Anna; Isola, Jorma; Kempas, Minna; Le Joncour, Vadim; Laakkonen, Pirjo; Joensuu, Heikki; Barok, Mark Share Save
Optimizing treatment strategies for HER2-positive breast and gastric cancer: preclinical evaluation of disitamab vedotin, trastuzumab emtansine, trastuzumab deruxtecan, and their combinations therapies in mouse models Pourjamal, N.; Le Joncour, V.; Vereb, G.; Honkamaki, C.; Isola, J.; Leyton, J. V.; Pirjo, L.; Heikki, J.; Barok, M. Share Save
Transcriptomic analysis of intestine following administration of a transglutaminase 2 inhibitor to prevent gluten-induced intestinal damage in celiac disease Dotsenko, Valeriia; Tewes, Bernhard; Hils, Martin; Pasternack, Ralf; Isola, Jorma; Taavela, Juha; Popp, Alina; Sarin, Jani; Huhtala, Heini; Hiltunen, Pauliina; Zimmermann, Timo; Mohrbacher, Ralf; Greinwald, Roland; Lundin, Knut E. A.; Schuppan, Detlef; Maki, Markku; Viiri, Keijo Share Save
Efficacy and safety of gluten peptide-based antigen-specific immunotherapy (Nexvax2) in adults with coeliac disease after bolus exposure to gluten (RESET CeD): an interim analysis of a terminated randomised, double-blind, placebo-controlled phase 2 study Tye-Din, Jason A.; Daveson, A. James M.; Goel, Gautam; Goldstein, Kaela E.; Hand, Holly L.; Neff, Kristin M.; Popp, Alina; Taavela, Juha; Maki, Markku; Isola, Jorma; Williams, Leslie J.; Truitt, Kenneth E.; Anderson, Robert P. Share Save
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Healthy and pro-inflammatory gut ecology plays a crucial role in the digestion and tolerance of a novel Gluten Friendly™ bread in celiac subjects: a randomized, double blind, placebo control in vivo study Andriulli, Angelo; Bevilacqua, Antonio; Palmieri, Orazio; Latiano, Anna; Fontana, Rosanna; Gioffreda, Domenica; Castellana, Stefano; Mazza, Tommaso; Panza, Anna; Menzaghi, Claudia; Grandone, Elvira; di Mauro, Lazzaro; Decina, Ivana; Tricarico, Michele; Musaico, Daniela; Maki, Markku; Isola, Jorma; Popp, Alina; Taavela, Juha; Petruzzi, Leonardo; Sinigaglia, Milena; Corbo, Maria Rosaria; Lamacchia, Carmela Share Save
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A randomized trial of a transglutaminase 2 inhibitor for celiac disease Schuppan, Detlef; Maki, Markku; Lundin, Knut E. A.; Isola, Jorma; Friesing-Sosnik, Tina; Taavela, Juha; Popp, Alina; Koskenpato, Jari; Langhorst, Jost; Hovde, Oistein; Lahdeaho, Marja-Leena; Fusco, Stefano; Schumann, Michael; Torok, Helga P.; Kupcinskas, Juozas; Zopf, Yurdagul; Lohse, Ansgar W.; Scheinin, Mika; Kull, Karin; Biedermann, Luc; Byrnes, Valerie; Stallmach, Andreas; Jahnsen, Jorgen; Zeitz, Jonas; Mohrbacher, Ralf; Greinwald, Roland Share Save
Iron Transporter Protein Expressions in Children with Celiac Disease Repo, Marleena; Hannula, Markus; Taavela, Juha; Hyttinen, Jari; Isola, Jorma; Hiltunen, Pauliina; Popp, Alina; Kaukinen, Katri; Kurppa, Kalle; Lindfors, Katri Share Save
Deep learning identifies morphological features in breast cancer predictive of cancer ERBB2 status and trastuzumab treatment efficacy Bychkov, Dmitrii; Linder, Nina; Tiulpin, Aleksei; Kuecuekel, Hakan; Lundin, Mikael; Nordling, Stig; Sihto, Harri; Isola, Jorma; Lehtimaeki, Tiina; Kellokumpu-Lehtinen, Pirkko-Liisa; von Smitten, Karl; Joensuu, Heikki; Lundin, Johan Share Save
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Genome-Wide Transcriptomic Analysis of Intestinal Mucosa in Celiac Disease Patients on a Gluten-Free Diet and Postgluten Challenge Dotsenko, Valeriia; Oittinen, Mikko; Taavela, Juha; Popp, Alina; Peraaho, Markku; Staff, Synnove; Sarin, Jani; Leon, Francisco; Isola, Jorma; Maki, Markku; Viiri, Keijo Share Save
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Safety and efficacy of AMG 714 in adults with coeliac disease exposed to gluten challenge: a phase 2a, randomised, double-blind, placebo-controlled study Lahdeaho, Marja-Leena; Scheinin, Mika; Vuotikka, Pekka; Taavela, Juha; Popp, Alina; Laukkarinen, Johanna; Koffert, Jukka; Koivurova, Olli-Pekka; Pesu, Marko; Kivela, Laura; Lovro, Zsofia; Keisala, Joni; Isola, Jorma; Parnes, Jane R.; Leon, Francisco; Maki, Markku Share Save
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Breast cancer outcome prediction with tumour tissue images and machine learning Turkki, Riku; Byckhov, Dmitrii; Lundin, Mikael; Isola, Jorma; Nordling, Stig; Kovanen, Panu E.; Verrill, Clare; von Smitten, Karl; Joensuu, Heikki; Lundin, Johan; Linder, Nina Share Save
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Integrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer She, Qing-Bai; Gruvberger-Saal, Sofia K.; Maurer, Matthew; Chen, Yilun; Jumppanen, Mervi; Su, Tao; Dendy, Meaghan; Lau, Ying-Ka Ingar; Memeo, Lorenzo; Horlings, Hugo M.; van de Vijver, Marc J.; Isola, Jorma; Hibshoosh, Hanina; Rosen, Neal; Parsons, Ramon; Saal, Lao H. Share Save
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