Jon R. Lorsch - Publications, H-index & Citations

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Jon R. Lorsch

nih eunice kennedy shriver national institute of child health & human development (nichd)

55H-index

178Paper Count

1.1WCitation Count

Published Papers 50

Publication Date

NIGMS Sandbox: a learning platform toward democratizing cloud computing for biomedical research

BRIEFINGS IN BIOINFORMATICS

IF7.7

2024-10-07

PREAI

Lei, Ming; Matukumalli, Lakshmi K.; Arora, Krishan; Weber, Nick; Malashock, Rachel; Mao, Fenglou; Gregurick, Susan; Lorsch, Jon

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Applied research won't flourish without basic science

ELIFE

IF0

2024-09-10

OAAI

Lorsch, Jon R.; Tabak, Lawrence A.; Bertagnolli, Monica M.

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Transcriptome-wide analysis of the function of Ded1 in translation preinitiation complex assembly in a reconstituted in vitro system

ELIFE

IF0

2024-04-04

OAAI

Zhou, Fujun; Bocetti, Julie M.; Hou, Meizhen; Qin, Daoming; Hinnebusch, Alan G.; Lorsch, Jon R.

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The All of Us Research Program is an opportunity to enhance the diversity of US biomedical research

NATURE MEDICINE

IF50

2024-02-19

PREAI

Bianchi, Diana W.; Brennan, Patricia Flatley; Chiang, Michael F.; Criswell, Lindsey A.; D'Souza, Rena N.; Gibbons, Gary H.; Gilman, James K.; Gordon, Joshua A.; Green, Eric D.; Gregurick, Susan; Hodes, Richard J.; Kilmarx, Peter H.; Koob, George F.; Koroshetz, Walter J.; Langevin, Helene M.; Lorsch, Jon R.; Marrazzo, Jeanne M.; Perez-Stable, Eliseo J.; Rathmell, W. Kimryn; Rodgers, Griffin P.; Rutter, Joni L.; Simoni, Jane M.; Tromberg, Bruce J.; Tucci, Debara L.; Volkow, Nora D.; Woychik, Rick; Zenk, Shannon N.; Kozlowski, Elyse; Peterson, Rachele S.; Ginsburg, Geoffrey S.; Denny, Joshua C.

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Intragenic suppressor mutations restore GTPase and translation functions of a eukaryotic initiation factor 5B Switch II mutant

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Shin, Byung-Sik; Acker, Michael G.; Maag, David; Kim, Joo-Ran; Lorsch, Jon R.; Dever, Thomas E.

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Coupled release of eukaryotic translation initiation factors 5B and 1A from 80S ribosomes following subunit joining

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Fringer, Jeanne M.; Acker, Michael G.; Fekete, Christie A.; Lorsch, Jon R.; Dever, Thomas E.

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rRNA Suppressor of a Eukaryotic Translation Initiation Factor 5B/Initiation Factor 2 Mutant Reveals a Binding Site for Translational GTPases on the Small Ribosomal Subunit

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-21

OAAI

Shin, Byung-Sik; Kim, Joo-Ran; Acker, Michael G.; Maher, Kathryn N.; Lorsch, Jon R.; Dever, Thomas E.

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Developing a culture of safety in biomedical research training

MOLECULAR BIOLOGY OF THE CELL

IF2.7

2020-10-15

OAAI

Bond, Michelle R.; Gammie, Alison E.; Lorsch, Jon R.

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Distinct interactions of eIF4A and eIF4E with RNA helicase Ded1 stimulate translation in vivo

ELIFE

IF0

2020-05-29

OAAI

Gulay, Suna; Gupta, Neha; Lorsch, Jon R.; Hinnebusch, Alan G.

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elF1 discriminates against suboptimal initiation sites to prevent excessive uORF translation genome-wide

RNA

IF5

2020-01-08

OAAI

Zhou, Fujun; Zhang, Hongen; Kulkarni, Shardul D.; Lorsch, Jon R.; Hinnebusch, Alan G.

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Functional interplay between DEAD-box RNA helicases Ded1 and Dbp1 in preinitiation complex attachment and scanning on structured mRNAs in vivo

NUCLEIC ACIDS RESEARCH

IF13.1

2019-07-12

OAAI

Sen, Neelam Dabas; Gupta, Neha; Archer, Stuart K.; Preiss, Thomas; Lorsch, Jon R.; Hinnebusch, Alan G.

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Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition

ELIFE

IF0

2018-11-30

OAAI

Luis Llacer, Jose; Hussain, Tanweer; Saini, Adesh K.; Nanda, Jagpreet Singh; Kaur, Sukhvir; Gordiyenko, Yuliya; Kumar, Rakesh; Hinnebusch, Alan G.; Lorsch, Jon R.; Ramakrishnan, Venki

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Yeast Ded1 promotes 48S translation pre-initiation complex assembly in an mRNA-specific and eIF4F-dependent manner

ELIFE

IF0

2018-10-03

OAAI

Gupta, Neha; Lorsch, Jon R.; Hinnebusch, Alan G.

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eIF1A residues implicated in cancer stabilize translation preinitiation complexes and favor suboptimal initiation sites in yeast

ELIFE

IF0

2017-12-05

OAAI

Martin-Marcos, Pilar; Zhou, Fujun; Karunasiri, Charm; Zhang, Fan; Dong, Jinsheng; Nanda, Jagpreet; Kulkarmi, Shardul D.; Sen, Neelam Dabas; Tamame, Mercedes; Zeschnigk, Michael; Lorsch, Jon R.; Hinnebusch, Alan G.

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Yeast eIF4A enhances recruitment of mRNAs regardless of their structural complexity

ELIFE

IF0

2017-11-30

OAAI

Yourik, Paul; Aitken, Colin Echeverria; Zhou, Fujun; Gupta, Neha; Hinnebusch, Alan G.; Lorsch, Jon R.

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Rps3/uS3 promotes mRNA binding at the 40S ribosome entry channel and stabilizes preinitiation complexes at start codons

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-02-21

OAAI

Dong, Jinsheng; Aitken, Colin Echeverria; Thakur, Anil; Shin, Byung-Sik; Lorsch, Jon R.; Hinnebusch, Alan G.

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Active yeast ribosome preparation using monolithic anion exchange chromatography

RNA BIOLOGY

IF3.4

2017-01-19

OAAI

Munoz, Antonio M.; Yourik, Paul; Rajagopal, Vaishnavi; Nanda, Jagpreet S.; Lorsch, Jon R.; Walker, Sarah E.

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Eukaryotic translation initiation factor 3 plays distinct roles at the mRNA entry and exit channels of the ribosomal preinitiation complex

ELIFE

IF0

2016-10-26

OAAI

Aitken, Colin Echeverria; Beznoskova, Petra; Vlckova, Vladislava; Chiu, Wen-Ling; Zhou, Fujun; Valasek, Leos Shivaya; Hinnebusch, Alan G.; Lorsch, Jon R.

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Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex

MOLECULAR CELL

IF16.6

2015-08-01

181

OAAI

Llacer, Jose L.; Hussain, Tanweer; Marler, Laura; Aitken, Colin Echeverria; Thakur, Anil; Lorsch, Jon R.; Hinnebusch, Alan G.; Ramakrishnan, V.

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Eukaryotic translation initiation factor eIF5 promotes the accuracy of start codon recognition by regulating Pi release and conformational transitions of the preinitiation complex (vol 42, pg 9623, 2014)

NUCLEIC ACIDS RESEARCH

IF13.1

2015-05-18

OAAI

Saini, Adesh K.; Nanda, Jagpreet S.; Martin-Marcos, Pilar; Dong, Jinsheng; Zhang, Fan; Bhardwaj, Monika; Lorsch, Jon R.; Hinnebusch, Alan G.

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Research Directions