Not logged in Single-cell transcriptional consequences of leukaemogenic SETBP1 mutations Trinh, Mi K.; Anderson, Nathaniel D.; Young, Matthew D.; Whitfield, Holly J.; Parks, Conor; Ogbonnah, Toochi; Oszlanczi, Agnes; Zhou, Di; Robertson, Emilia R.; Hodder, Angus; Thomas, Rebecca; Straathof, Karin; Adams, Stuart; Bartram, Jack; Summerfield, Nuala; Behjati, Sam Share Save
A cycling, progenitor-like cell population at the base of atypical teratoid rhabdoid tumor subtype differentiation trajectories Blanco-Carmona, Enrique; Paassen, Irene; He, Jiayou; Demartino, Jeff; Bullesbach, Annette; Anderson, Nadia; Buhl, Juliane L.; Federico, Aniello; Mauermann, Monika; Brok, Mariel; Straathof, Karin; Behjati, Sam; Vibhakar, Rajeev; Donson, Andrew M.; Foreman, Nicholas K.; Shaw, Mckenzie; Fruhwald, Michael C.; Korshunov, Andrey; Hasselblatt, Martin; Thomas, Christian; Franke, Niels; Kranendonk, Mariette E. G.; Hoving, Eelco W.; Jaeger, Natalie; Johann, Pascal D.; Pfister, Stefan M.; Filbin, Mariella G.; Kool, Marcel; Drost, Jarno Share Save
TUMOR INFLAMMATION-ASSOCIATED NEUROTOXICITY (TIAN): A TOXICITY SYNDROME IN PATIENTS TREATED WITH IMMUNOTHERAPY FOR CENTRAL NERVOUS SYSTEM TUMORS Mahdi, Jasia; Dietrich, Jorg; Straathof, Karin; Roddie, Claire; Scott, Brian J.; Davidson, Tom Belle; Prolo, Laura; Batchelor, Tracy T.; Campen, Cynthia J.; Davis, Kara L.; Gust, Juliane; Lim, Michael; Majzner, Robbie G.; Park, Julie R.; Partap, Sonia; Ramakrishna, Sneha; Richards, Rebecca; Schultz, Liora; Vitanza, Nicholas A.; Wang, Leo D.; Mackall, Crystal L.; Monje, Michelle Share Save
The Virtual Child Gilbertson, Richard J.; Behjati, Sam; Boettcher, Anna-Lisa; Bronner, Marianne E.; Burridge, Matthew; Clausing, Henrick; Clifford, Harry; Danaher, Tracey; Donovan, Laura K.; Drost, Jarno; Eggermont, Alexander M. M.; Emerson, Chris; Flores, Mona G.; Hamerlik, Petra; Jabado, Nada; Jones, Andrew; Kaessmann, Henrick; Kleinman, Claudia L.; Kool, Marcel; Kutscher, Lena M.; Lindberg, Gavin; Linnane, Emily; Marioni, John C.; Maris, John M.; Monje, Michelle; Macaskill, Alexandra; Niederer, Steven; Northcott, Paul A.; Peeters, Elizabeth; Plieger-van Solkema, Willemijn; Preussner, Liane; Rios, Anne C.; Rippe, Karsten; Sandford, Peter; Sgourakis, Nikolaos G.; Shlien, Adam; Smith, Pete; Straathof, Karin; Sullivan, Patrick J.; Suva, Mario L.; Taylor, Michael D.; Thompson, Emma; Vento-Tormo, Roser; Wainwright, Brandon J.; Wechsler-Reya, Robert J.; Westermann, Frank; Winslade, Shannon; Al-Lazikani, Bissan; Pfister, Stefan M. Share Save
TUMOR INFLAMMATION-ASSOCIATED NEUROTOXICITY (TIAN): A TOXICITY SYNDROME IN PATIENTS TREATED WITH IMMUNOTHERAPY FOR CENTRAL NERVOUS SYSTEM TUMORS Mahdi, Jasia; Dietrich, Jorg; Straathof, Karin; Roddie, Claire; Scott, Brian; Davidson, Tom Belle; Prolo, Laura; Batchelor, Tracy; Campen, Cynthia; Davis, Kara; Gust, Juliane; Lim, Michael; Majzner, Robbie; Park, Julie; Partap, Sonia; Ramakrishna, Sneha; Richards, Rebecca; Schultz, Liora; Vitanza, Nicholas; Wang, Leo; Mackall, Crystal; Monje, Michelle Share Save
Tumor inflammation-associated neurotoxicity Mahdi, Jasia; Dietrich, Jorg; Straathof, Karin; Roddie, Claire; Scott, Brian J.; Davidson, Tom Belle; Prolo, Laura M.; Batchelor, Tracy T.; Campen, Cynthia J.; Davis, Kara L.; Gust, Juliane; Lim, Michael; Majzner, Robbie G.; Park, Julie R.; Partap, Sonia; Ramakrishna, Sneha; Richards, Rebecca; Schultz, Liora; Vitanza, Nicholas A.; Wang, Leo D.; Mackall, Crystal L.; Monje, Michelle Share Save
Evaluating preclinical evidence for clinical translation in childhood brain tumours: Guidelines from the CONNECT, PNOC, and ITCC brain networks Jones, Chris; Straathof, Karin; Fouladi, Maryam; Hargrave, Darren; Prados, Michael; Resnick, Adam; Doz, Francois; Jones, David T. W.; Mueller, Sabine Share Save
Precise identification of cancer cells from allelic imbalances in single cell transcriptomes Trinh, Mi K.; Pacyna, Clarissa N.; Kildisiute, Gerda; Thevanesan, Christine; Piapi, Alice; Ambridge, Kirsty; Anderson, Nathaniel D.; Khabirova, Eleonora; Prigmore, Elena; Straathof, Karin; Behjati, Sam; Young, Matthew D. Share Save
Single-cell transcriptomics reveals a distinct developmental state of KMT2A-rearranged infant B-cell acute lymphoblastic leukemia Khabirova, Eleonora; Jardine, Laura; Coorens, Tim H. H.; Webb, Simone; Treger, Taryn D.; Engelbert, Justin; Porter, Tarryn; Prigmore, Elena; Collord, Grace; Piapi, Alice; Teichmann, Sarah A.; Inglott, Sarah; Williams, Owen; Heidenreich, Olaf; Young, Matthew D.; Straathof, Karin; Bomken, Simon; Bartram, Jack; Haniffa, Muzlifah; Behjati, Sam Share Save
Single cell derived mRNA signals across human kidney tumors Young, Matthew D.; Mitchell, Thomas J.; Custers, Lars; Margaritis, Thanasis; Morales-Rodriguez, Francisco; Kwakwa, Kwasi; Khabirova, Eleonora; Kildisiute, Gerda; Oliver, Thomas R. W.; de Krijger, Ronald R.; van den Heuvel-Eibrink, Marry M.; Comitani, Federico; Piapi, Alice; Bugallo-Blanco, Eva; Thevanesan, Christine; Burke, Christina; Prigmore, Elena; Ambridge, Kirsty; Roberts, Kenny; Braga, Felipe A. Vieira; Coorens, Tim H. H.; Del Valle, Ignacio; Wilbrey-Clark, Anna; Mamanova, Lira; Stewart, Grant D.; Gnanapragasam, Vincent J.; Rampling, Dyanne; Sebire, Neil; Coleman, Nicholas; Hook, Liz; Warren, Anne; Haniffa, Muzlifah; Kool, Marcel; Pfister, Stefan M.; Achermann, John C.; He, Xiaoling; Barker, Roger A.; Shlien, Adam; Bayraktar, Omer A.; Teichmann, Sarah A.; Holstege, Frank C.; Meyer, Kerstin B.; Drost, Jarno; Straathof, Karin; Behjati, Sam Share Save
Somatic mutations and single-cell transcriptomes reveal the root of malignant rhabdoid tumours Custers, Lars; Khabirova, Eleonora; Coorens, Tim H. H.; Oliver, Thomas R. W.; Calandrini, Camilla; Young, Matthew D.; Braga, Felipe A. Vieira; Ellis, Peter; Mamanova, Lira; Segers, Heidi; Maat, Arie; Kool, Marcel; Hoving, Eelco W.; Van den Heuvel-Eibrink, Marry M.; Nicholson, James; Straathof, Karin; Hook, Liz; de Krijger, Ronald R.; Trayers, Claire; Allinson, Kieren; Behjati, Sam; Drost, Jarno Share Save
Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell Kildisiute, Gerda; Kholosy, Waleed M.; Young, Matthew D.; Roberts, Kenny; Elmentaite, Rasa; van Hooff, Sander R.; Pacyna, Clarissa N.; Khabirova, Eleonora; Piapi, Alice; Thevanesan, Christine; Bugallo-Blanco, Eva; Burke, Christina; Mamanova, Lira; Keller, Kaylee M.; Langenberg-Ververgaert, Karin P. S.; Lijnzaad, Philip; Margaritis, Thanasis; Holstege, Frank C. P.; Tas, Michelle L.; Wijnen, Marc H. W. A.; van Noesel, Max M.; Del Valle, Ignacio; Barone, Giuseppe; van der Linden, Reinier; Duncan, Catriona; Anderson, John; Achermann, John C.; Haniffa, Muzlifah; Teichmann, Sarah A.; Rampling, Dyanne; Sebire, Neil J.; He, Xiaoling; de Krijger, Ronald R.; Barker, Roger A.; Meyer, Kerstin B.; Bayraktar, Omer; Straathof, Karin; Molenaar, Jan J.; Behjati, Sam Share Save
Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of glioblastoma Agliardi, Giulia; Liuzzi, Anna Rita; Hotblack, Alastair; De Feo, Donatella; Nunez, Nicolas; Stowe, Cassandra L.; Friebel, Ekaterina; Nannini, Francesco; Rindlisbacher, Lukas; Roberts, Thomas A.; Ramasawmy, Rajiv; Williams, Iwan P.; Siow, Bernard M.; Lythgoe, Mark F.; Kalber, Tammy L.; Quezada, Sergio A.; Pule, Martin A.; Tugues, Sonia; Straathof, Karin; Becher, Burkhard Share Save
Antitumor activity without on-target off-tumor toxicity of GD2-chimeric antigen receptor T cells in patients with neuroblastoma Straathof, Karin; Flutter, Barry; Wallace, Rebecca; Jain, Neha; Loka, Thalia; Depani, Sarita; Wright, Gary; Thomas, Simon; Cheung, Gordon Weng-Kit; Gileadi, Talia; Stafford, Sian; Kokalaki, Evangelia; Barton, Jack; Marriott, Clare; Rampling, Dyanne; Ogunbiyi, Olumide; Akarca, Ayse U.; Marafioti, Teresa; Inglott, Sarah; Gilmour, Kimberly; Al-Hajj, Muhammad; Day, William; McHugh, Kieran; Biassoni, Lorenzo; Sizer, Natalie; Barton, Claire; Edwards, David; Dragoni, Ilaria; Silvester, Julie; Dyer, Karen; Traub, Stephanie; Elson, Lily; Brook, Sue; Westwood, Nigel; Robson, Lesley; Bedi, Ami; Howe, Karen; Barry, Ailish; Duncan, Catriona; Barone, Giuseppe; Pule, Martin; Anderson, John Share Save
Pediatric pan-central nervous system tumor analysis of immune-cell infiltration identifies correlates of antitumor immunity Grabovska, Yura; Mackay, Alan; O'Hare, Patricia; Crosier, Stephen; Finetti, Martina; Schwalbe, Edward C.; Pickles, Jessica C.; Fairchild, Amy R.; Avery, Aimee; Cockle, Julia; Hill, Rebecca; Lindsey, Janet; Hicks, Debbie; Kristiansen, Mark; Chalker, Jane; Anderson, John; Hargrave, Darren; Jacques, Thomas S.; Straathof, Karin; Bailey, Simon; Jones, Chris; Clifford, Steven C.; Williamson, Daniel Share Save
A Cancer Research UK phase I trial of anti-GD2 chimeric antigen receptor (CAR) transduced T-cells (1RG-CART) in patients with relapsed or refractory neuroblastoma Straathof, Karin; Flutter, Barry; Wallace, Rebecca; Thomas, Simon; Cheung, Gordon; Collura, Angela; Gileadi, Talia; Barton, Jack; Wright, Gary; Inglott, Sarah; Edwards, David; Barton, Claire; Dyer, Karen; Westwood, Nigel; Loka, Thalia; Depani, Sarita; Howe, Karen; Barone, Giuseppe; Pule, Martin; Anderson, John Share Save
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Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy Di Stasi, Antonio; Tey, Siok-Keen; Dotti, Gianpietro; Fujita, Yuriko; Kennedy-Nasser, Alana; Martinez, Caridad; Straathof, Karin; Liu, Enli; Durett, April G.; Grilley, Bambi; Liu, Hao; Cruz, Conrad R.; Savoldo, Barbara; Gee, Adrian P.; Schindler, John; Krance, Robert A.; Heslop, Helen E.; Spencer, David M.; Rooney, Cliona M.; Brenner, Malcolm K. Share Save
Adoptive Transfer of EBV-specific T Cells Results in Sustained Clinical Responses in Patients With Locoregional Nasopharyngeal Carcinoma Louis, Chrystal U.; Straathof, Karin; Bollard, Catherine M.; Ennamuri, Sravya; Gerken, Claudia; Lopez, Teresita T.; Huls, M. Helen; Sheehan, Andrea; Wu, Meng-Fen; Liu, Hao; Gee, Adrian; Brenner, Malcolm K.; Rooney, Cliona M.; Heslop, Helen E.; Gottschalk, Stephen Share Save
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