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Liver lipid droplet cholesterol content is a key determinant of metabolic dysfunction-associated steatohepatitis Sakuma, Ikki; Gaspar, Rafael C.; Nasiri, Ali R.; Dufour, Sylvie; Kahn, Mario; Zheng, Jie; Lamoia, Traci E.; Guerra, Mateus T.; Taki, Yuki; Kawashima, Yusuke; Yimlamai, Dean; Perelis, Mark; Vatner, Daniel F.; Petersen, Kitt Falk; Huttasch, Maximilian; Knebel, Birgit; Kahl, Sabine; Roden, Michael; Samuel, Varman T.; Tanaka, Tomoaki; Shulman, Gerald I. Share Save
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CIDEB and CGI-58 Regulate Liver Lipid Droplet Size with Cholesterol Content, Linking to Inflammation and Fibrosis in Metabolic Dysfunction-Associated Steatohepatitis Sakuma, Ikki; Gaspar, Rafael C.; Nasiri, Ali; Kahn, Mario; Zheng, Jie; Guerra, Mateus; Yimlamai, Dean; Murray, Sue; Perelis, Mark; Barnes, William; Vatner, Daniel F.; Petersen, Kitt; Samuel, Varman; Shulman, Gerald I. Share Save
Coenzyme A Synthase Knockdown Alleviates Metabolic Dysfunction-Associated Steatohepatitis via Decreasing Cholesterol in Liver Lipid Droplets Sakuma, Ikki; Gaspar, Rafael C.; Nasiri, Ali; Kahn, Mario; Guerra, Mateus; Yimlamai, Dean; Murray, Sue; Perelis, Mark; Barnes, William; Vatner, Daniel F.; Petersen, Kitt; Samuel, Varman; Shulman, Gerald I. Share Save
CIDEB Knockdown Promotes Increased Hepatic Mitochondrial Fat Oxidation and Reverses Hepatic Steatosis and Hepatic Insulin Resistance by the PKCe-Insulin Receptor Kinase Pathway Zheng, Jie; Nasiri, Ali; Gaspar, Rafael C.; Hubbard, Brandon T.; Sakuma, Ikki; Ma, Xiaoxian; Murray, Sue; Perelis, Mark; Barnes, William; Samuel, Varman; Petersen, Kitt; Shulman, Gerald I. Share Save
Lysophosphatidic acid triggers inflammation in the liver and white adipose tissue in rat models of 1-acyl-sn- glycerol-3-phosphate 2 and overnutrition Sakuma, Ikki; Gaspar, Rafael C.; Luukkonen, Panu K.; Kahn, Mario; Zhang, Dongyan; Zhang, Xuchen; Murray, Sue; Golla, Jaya Prakash; Vatner, Daniel F.; Samuel, Varman T.; Petersen, Kitt Falk; Shulman, Gerald I. Share Save
The PNPLA3 I148M variant increases ketogenesis and decreases hepatic de novo lipogenesis and mitochondrial function in humans Luukkonen, Panu K.; Porthan, Kimmo; Ahlholm, Noora; Rosqvist, Fredrik; Dufour, Sylvie; Zhang, Xian-Man; Lehtimaki, Tiina E.; Seppanen, Wenla; Orho-Melander, Marju; Hodson, Leanne; Petersen, Kitt Falk; Shulman, Gerald I.; Yki-Jarvinen, Hannele Share Save
Effect of Burosumab on Muscle Function and Strength, and Rates of ATP Synthesis in Skeletal Muscle in Adults With XLH Insogna, Karl L.; Sullivan, Rebecca; Parziale, Stephen; Deng, Yanhong; Carrano, Diana; Simpson, Christine; Dufour, Sylvie; Carpenter, Thomas; Petersen, Kitt Falk Share Save
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Inhibition of HSD17B13 protects against liver fibrosis by inhibition of pyrimidine catabolism in nonalcoholic steatohepatitis Luukkonen, Panu K.; Sakuma, Ikki; Gaspar, Rafael C.; Mooring, Meghan; Nasiri, Ali; Kahn, Mario; Zhang, Xian-Man; Zhang, Dongyan; Sammalkorpi, Henna; Penttilae, Anne K.; Orho-Melander, Marju; Arola, Johanna; Juuti, Anne; Zhang, Xuchen; Yimlamai, Dean; Yki-Jaervinen, Hannele; Petersen, Kitt Falk; Shulman, Gerald I. Share Save
Distinct subcellular localisation of intramyocellular lipids and reduced PKCε/PKCθ activity preserve muscle insulin sensitivity in exercise-trained mice Gaspar, Rafael C.; Lyu, Kun; Hubbard, Brandon T.; Leitner, Brooks P.; Luukkonen, Panu K.; Hirabara, Sandro M.; Sakuma, Ikki; Nasiri, Ali; Zhang, Dongyan; Kahn, Mario; Cline, Gary W.; Pauli, Jose Rodrigo; Perry, Rachel J.; Petersen, Kitt F.; Shulman, Gerald I. Share Save
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Lower Plasma Membrane Sn-1,2-Diacylglycerol Content and PKCepsilon/theta Activity Explain the Athlete's Paradox Gaspar, Rafael C.; Lyu, Kun; Hubbard, Brandon T.; Leitner, Brooks; Luukkonen, Panu; Hirabara, Sandro; Sakuma, Ikki; Nasiri, Ali; Zhang, Dongyan; Kahn, Mario; Cline, Gary; Pauli, Jose R.; Perry, Rachel J.; Petersen, Kitt; Shulman, Gerald I. Share Save
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Metabolic control analysis of hepatic glycogen synthesis in vivo Nozaki, Yuichi; Petersen, Max C.; Zhang, Dongyan; Vatner, Daniel F.; Perry, Rachel J.; Abulizi, Abudukadier; Haedersdal, Sofie; Zhang, Xian-Man; Butrico, Gina M.; Samuel, Varman T.; Mason, Graeme F.; Cline, Gary W.; Petersen, Kitt F.; Rothman, Douglas L.; Shulman, Gerald I. Share Save
Effect of a ketogenic diet on hepatic steatosis and hepatic mitochondrial metabolism in nonalcoholic fatty liver disease Luukkonen, Panu K.; Dufour, Sylvie; Lyu, Kun; Zhang, Xian-Man; Hakkarainen, Antti; Lehtimaki, Tiina E.; Cline, Gary W.; Petersen, Kitt Falk; Shulman, Gerald I.; Yki-Jarvinen, Hannele Share Save
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