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C

Carlos T. Moraes

university of miami

89H-index
318Paper Count
2.7WCitation Count
Published Papers 151
Publication Date
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The power of one: The unexpected benefits of correcting a single tissue in multisystem mitochondrial disease
errMolecular Therapy
IF12
err2026-07-20
err0
PREAI
errCarlos T. Moraes
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Transient muscle expression of mitoARCUS in mice leads to a sustained reduction in pathogenic mtDNA content and improves muscle function
errMolecular Therapy
IF12
err2025-12-24
err0
PREAI
errSandra R. Bacman; Wendy Shoop; C.Spencer Henley-Beasley; Rhese Thompson; Jose Domingo Barrera-Paez; Lise-Michelle Theard; Monica Rodriguez-Silva; Cassandra Gorsuch; Elisabeth R. Barton; Carlos T. Moraes
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Mito-TALENs reduce mitochondrial DNA mutation load following pronuclear transfer
errHUMAN REPRODUCTION
IF6.1
err2025-06-01
err0
errOAAI
errCastelluccio, N.; Rybouchkin, A.; Bacman, S. R.; Symoens, S.; Coucke, P.; Menten, B.; Moraes, C. T.; De Spiegelaere, W.; Stoop, D.; Heindryckx, B.
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Correcting a pathogenic mitochondrial DNA mutation by base editing in mice
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2025-01-29
err0
PREAI
errBarrera-Paez, Jose D.; Bacman, Sandra R.; Balla, Till; Van Booven, Derek; Gannamedi, Durga P.; Stewart, James B.; Mok, Beverly; Liu, David R.; Lombard, David B.; Griswold, Anthony J.; Nedialkova, Danny D.; Moraes, Carlos T.
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NEK10 kinase ablation affects mitochondrial morphology, function and protein phosphorylation status
errProteome Science
IF1.6
err2024-10-08
err0
errOAAI
errAndressa Peres de Oliveira; Claudia D. C. Navarro; Pedro Rafael F. Dias; Tania Arguello; Brittni R. Walker; Sandra R. Bacman; Lizandra Maia Sousa; Roger F. Castilho; Sílvio R. Consonni; Carlos T. Moraes; Jörg Kobarg
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Restoration of defective oxidative phosphorylation to a subset of neurons prevents mitochondrial encephalopathy
errEMBO MOLECULAR MEDICINE
IF8.3
err2024-08-21
err0
errOAAI
errWalker, Brittni R.; Theard, Lise-Michelle; Pinto, Milena; Rodriguez-Silva, Monica; Bacman, Sandra R.; Moraes, Carlos T.
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errSave
Tools for editing the mammalian mitochondrial genome
errHUMAN MOLECULAR GENETICS
IF3.2
err2024-05-23
err2
PREAI
errMoraes, Carlos T.
errShare
errSave
Absence of both MGME1 and POLG EXO abolishes mtDNA whereas absence of either creates unique mtDNA duplications
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-04-01
err3
errOAAI
errGonzalez, Christian D.; Nissanka, Nadee; Van Booven, Derek; Griswold, Anthony J.; Moraes, Carlos T.
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mitoTALEN reduces the mutant mtDNA load in neurons
errMOLECULAR THERAPY NUCLEIC ACIDS
IF6.1
err2024-03-01
err7
errOAAI
errBacman, Sandra R.; Barrera-Paez, Jose Domingo; Pinto, Milena; Van Booven, Derek; Stewart, James B.; Griswold, Anthony J.; Moraes, Carlos T.
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errSave
Linear DNA-driven recombination in mammalian mitochondria
errNUCLEIC ACIDS RESEARCH
IF13.1
err2024-02-01
err2
errOAAI
errFragkoulis, Georgios; Hangas, Anu; Fekete, Zsofia; Michell, Craig; Moraes, Carlos T.; Willcox, Smaranda; Griffith, Jack D.; Goffart, Steffi; Pohjoismaeki, Jaakko L. O.
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errSave
PI3K signaling promotes formation of lipid-laden foamy macrophages at the spinal cord injury site
errNEUROBIOLOGY OF DISEASE
IF5.6
err2024-01-01
err6
errOAAI
errRyan, Christine B.; Choi, James S.; Kang, Brian; Herr, Seth; Pereira, Claudia; Moraes, Carlos T.; Al -Ali, Hassan; Lee, Jae K.
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Efficient elimination of MELAS-associated m.3243G mutant mitochondrial DNA by an engineered mitoARCUS nuclease
errNATURE METABOLISM
IF20.8
err2023-11-30
err6
errOAAI
errShoop, Wendy K.; Lape, Janel; Trum, Megan; Powell, Alea; Sevigny, Emma; Mischler, Adam; Bacman, Sandra R.; Fontanesi, Flavia; Smith, Jeff; Jantz, Derek; Gorsuch, Cassandra L.; Moraes, Carlos T.
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Mitochondrial dysfunction characterized in human induced pluripotent stem cell disease models in MELAS syndrome: A brief summary
errMitochondrion
IF4.5
err2023-09-01
err1
PREAI
errLatchman, Kumarie; Saporta, Mario; Moraes, Carlos T.
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A Defect in Mitochondrial Complex III but Not in Complexes I or IV Causes Early β-Cell Dysfunction and Hyperglycemia in Mice
errDIABETES
IF7.5
err2023-06-21
err8
errOAAI
errLang, Anna L.; Nissanka, Nadee; Louzada, Ruy A.; Tamayo, Alejandro; Pereira, Elizabeth; Moraes, Carlos T.; Caicedo, Alejandro
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errSave
A disease-associated G5703A mutation in human mitochondrial DNA causes a conformational change and a marked decrease in steady-state levels of mitochondrial tRNA(Asn)
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-29
err57
errOAAI
errHao, HL; Moraes, CT
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errSave
Cytochrome c oxidase is required for the assembly/stability of respiratory complex I in mouse fibroblasts
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err224
errOAAI
errDiaz, Francisca; Fukui, Hirokazu; Garcia, Sofia; Moraes, Carlos T.
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Role of cytochrome c in apoptosis:: Increased sensitivity to tumor necrosis factor alpha is associated with respiratory defects but not with lack of cytochrome c release
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err69
errOAAI
errVempati, Uma D.; Diaz, Francisca; Barrientos, Antoni; Narisawa, Sonoko; Mian, Abdul M.; Millan, Jose Luis; Boise, Lawrence H.; Moraes, Carlos T.
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Loss of Mcl-1 protein and inhibition of electron transport chain together induce anoxic cell death
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err48
errOAAI
errBrunelle, Joslyn K.; Shroff, Emelyn H.; Perlman, Harris; Strasser, Andreas; Moraes, Carlos T.; Flavell, Richard A.; Danial, Nika N.; Keith, Brian; Thompson, Craig B.; Chandel, Navdeep S.
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Cells Lacking Rieske Iron-Sulfur Protein Have a Reactive Oxygen Species-Associated Decrease in Respiratory Complexes I and IV
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err112
errOAAI
errDiaz, Francisca; Antonio Enriquez, Jose; Moraesa, Carlos T.
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Mitochondrial genome engineering coming-of-age (vol 38, pg 869, 2022)
errTRENDS IN GENETICS
IF16.3
err2023-01-01
err0
errOAAI
errBarrera-Paez, Jose Domingo; Moraes, Carlos T.
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Research Directions

No research directions
Co-authors
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Bruce M. Spiegelman
H-index: 186 · Papers: 471
A
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M
Michael P. Murphy
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