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Coronavirus endoribonuclease antagonizes ZBP1-mediated necroptosis and delays multiple cell death pathways Evdokimova, Monika; Feng, Shuchen; Caobi, Allen; Moreira, Fernando R.; Jones, Dakota; Alysandratos, Konstantinos-Dionysios; Tully, Ena S.; Kotton, Darrell N.; Boyd, David F.; Banach, Bridget S.; Kirchdoerfer, Robert N.; Saeed, Mohsan; Baker, Susan C. Share Save
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The HLA-II immunopeptidome of SARS-CoV-2 Weingarten-Gabbay, Shira; Chen, Da-Yuan; Sarkizova, Siranush; Taylor, Hannah B.; Gentili, Matteo; Hernandez, Gabrielle M.; Pearlman, Leah R.; Bauer, Matthew R.; Rice, Charles M.; Clauser, Karl R.; Hacohen, Nir; Carr, Steven A.; Abelin, Jennifer G.; Saeed, Mohsan; Sabeti, Pardis C. Share Save
High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface Datta, Suprama; Chen, Da-Yuan; Tavares, Alexander H.; Reyes-Robles, Tamara; Ryu, Keun Ah; Khan, Nazimuddin; Bechtel, Tyler J.; Bertoch, Jayde M.; White, Cory H.; Hazuda, Daria J.; Vora, Kalpit A.; Hett, Erik C.; Fadeyi, Olugbeminiyi O.; Oslund, Rob C.; Emili, Andrew; Saeed, Mohsan Share Save
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Optimized ACE2 decoys neutralize antibody-resistant SARS-CoV-2 variants through functional receptor mimicry and treat infection in vivo Torchia, James A.; Tavares, Alexander H.; Carstensen, Laura S.; Chen, Da -Yuan; Huang, Jessie; Xiao, Tianshu; Mukherjee, Sonia; Reeves, Patrick M.; Tu, Hua; Sluder, Ann E.; Chen, Bing; Kotton, Darrell N.; Bowen, Richard A.; Saeed, Mohsan; Poznansky, Mark C.; Freeman, Gordon J. Share Save
A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants Han, Yuling; Tan, Lei; Zhou, Ting; Yang, Liuliu; Carrau, Lucia; Lacko, Lauretta A.; Saeed, Mohsan; Zhu, Jiajun; Zhao, Zeping; Nilsson-Payant, Benjamin E.; Neto, Filipe Tenorio Lira; Cahir, Clare; Giani, Alice Maria; Chai, Jin Chou; Li, Yang; Dong, Xue; Moroziewicz, Dorota; Paull, Daniel; Zhang, Tuo; Koo, Soyeon; Tan, Christina; Danziger, Ron; Ba, Qian; Feng, Lingling; Chen, Zhengming; Zhong, Aaron; Wise, Gilbert J.; Xiang, Jenny Z.; Wang, Hui; Schwartz, Robert E.; tenOever, Benjamin R.; Noggle, Scott A.; Rice, Charles M.; Qi, Qibin; Evans, Todd; Chen, Shuibing Share Save
Proteomic elucidation of the targets and primary functions of the picornavirus 2A protease Serganov, Artem A.; Udi, Yael; Stein, Milana E.; Patel, Valay; Fridy, Peter C.; Rice, Charles M.; Saeed, Mohsan; Jacobs, Erica Y.; Chait, Brian T.; Rout, Michael P. Share Save
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Humanized mice reveal a macrophage-enriched gene signature defining human lung tissue protection during SARS-CoV-2 infection Kenney, Devin J.; O'Connell, Aoife K.; Turcinovic, Jacquelyn; Montanaro, Paige; Hekman, Ryan M.; Tamura, Tomokazu; Berneshawi, Andrew R.; Cafiero, Thomas R.; Al Abdullatif, Salam; Blum, Benjamin; Goldstein, Stanley, I; Heller, Brigitte L.; Gertje, Hans P.; Bullitt, Esther; Trachtenberg, Alexander J.; Chavez, Elizabeth; Nono, Evans Tuekam; Morrison, Catherine; Tseng, Anna E.; Sheikh, Amira; Kurnick, Susanna; Grosz, Kyle; Bosmann, Markus; Ericsson, Maria; Huber, Bertrand R.; Saeed, Mohsan; Balazs, Alejandro B.; Francis, Kevin P.; Klose, Alexander; Paragas, Neal; Campbell, Joshua D.; Connor, John H.; Emili, Andrew; Crossland, Nicholas A.; Ploss, Alexander; Douam, Florian Share Save
Fatal Neurodissemination and SARS-CoV-2 Tropism in K18-hACE2 Mice Is Only Partially Dependent on hACE2 Expression Carossino, Mariano; Kenney, Devin; O'Connell, Aoife K.; Montanaro, Paige; Tseng, Anna E.; Gertje, Hans P.; Grosz, Kyle A.; Ericsson, Maria; Huber, Bertrand R.; Kurnick, Susanna A.; Subramaniam, Saravanan; Kirkland, Thomas A.; Walker, Joel R.; Francis, Kevin P.; Klose, Alexander D.; Paragas, Neal; Bosmann, Markus; Saeed, Mohsan; Balasuriya, Udeni B. R.; Douam, Florian; Crossland, Nicholas A. Share Save
Susceptibilities of Human ACE2 Genetic Variants in Coronavirus Infection Ren, Wenlin; Zhu, Yunkai; Lan, Jun; Chen, Hedi; Wang, Yuyan; Shi, Hongyang; Feng, Fei; Chen, Da-Yuan; Close, Brianna; Zhao, Xiaomin; Wu, Jianping; Tian, Boxue; Yuan, Zhenghong; Zhou, Dongming; Saeed, Mohsan; Wang, Xinquan; Zhang, Rong; Ding, Qiang Share Save
SARS-CoV-2 Disrupts Proximal Elements in the JAK-STAT Pathway Chen, Da-Yuan; Khan, Nazimuddin; Close, Brianna J.; Goel, Raghuveera K.; Blum, Benjamin; Tavares, Alexander H.; Kenney, Devin; Conway, Hasahn L.; Ewoldt, Jourdan K.; Chitalia, Vipul C.; Crossland, Nicholas A.; Chen, Christopher S.; Kotton, Darrell N.; Baker, Susan C.; Fuchs, Serge Y.; Connor, John H.; Douam, Florian; Emili, Andrew; Saeed, Mohsan Share Save
Discovery of Quinoxaline-Based P1-P3 Macrocyclic NS3/4A Protease Inhibitors with Potent Activity against Drug-Resistant Hepatitis C Virus Variants Rao, Desaboini Nageswara; Zephyr, Jacqueto; Henes, Mina; Chan, Elise T.; Matthew, Ashley N.; Hedger, Adam K.; Conway, Hasahn L.; Saeed, Mohsan; Newton, Alicia; Petropoulos, Christos J.; Huang, Wei; Yilmaz, Nese Kurt; Schiffer, Celia A.; Ali, Akbar Share Save
Developing a SARS-CoV-2 Antigen Test Using Engineered Affinity Proteins Kim, Seunghyeon; Yee, Emma; Miller, Eric A.; Hao, Yining; Tay, Dousabel M. Y.; Sung, Ki-Joo; Jia, Huan; Johnson, Joseph M.; Saeed, Mohsan; Mace, Charles R.; Yurt, Deniz Yuksel; Sikes, Hadley D. Share Save
SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation Sanders, David W.; Jumper, Chanelle C.; Ackerman, Paul J.; Bracha, Dan; Donlic, Anita; Kim, Hahn; Kenney, Devin; Castello-Serrano, Ivan; Suzuki, Saori; Tamura, Tomokazu; Tavares, Alexander H.; Saeed, Mohsan; Holehouse, Alex S.; Ploss, Alexander; Levental, Ilya; Douam, Florian; Padera, Robert F.; Levy, Bruce D.; Brangwynne, Clifford P. Share Save
The in-vitro effect of famotidine on sars-cov-2 proteases and virus replication Loffredo, Madeline; Lucero, Hector; Chen, Da-Yuan; O'Connell, Aoife; Bergqvist, Simon; Munawar, Ahmad; Bandara, Asanga; De Graef, Steff; Weeks, Stephen D.; Douam, Florian; Saeed, Mohsan; Munawar, Ali H. Share Save
Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2 (vol 80, pg 1104, 2020) Hekman, Ryan M.; Hume, Adam J.; Goel, Raghuveera Kumar; Abo, Kristine M.; Huang, Jessie; Blum, Benjamin C.; Werder, Rhiannon B.; Suder, Ellen L.; Paul, Indranil; Phanse, Sadhna; Youssef, Ahmed; Alysandratos, Konstantinos D.; Padhorny, Dzmitry; Ojha, Sandeep; Mora-Martin, Alexandra; Kretov, Dmitry; Ash, Peter E. A.; Verma, Mamta; Zhao, Jian; Patten, J. J.; Villacorta-Martin, Carlos; Bolzan, Dante; Perea-Resa, Carlos; Bullitt, Esther; Hinds, Anne; Tilston-Lunel, Andrew; Varelas, Xaralabos; Farhangmehr, Shaghayegh; Braunschweig, Ulrich; Kwan, Julian H.; McComb, Mark; Basu, Avik; Saeed, Mohsan; Perissi, Valentina; Burks, Eric J.; Layne, Matthew D.; Connor, John H.; Davey, Robert; Cheng, Ji-Xin; Wolozin, Benjamin L.; Blencowe, Benjamin J.; Wuchty, Stefan; Lyons, Shawn M.; Kozakov, Dima; Cifuentes, Daniel; Blower, Michael; Kotton, Darrell N.; Wilson, Andrew A.; Muhlberger, Elke; Emili, Andrew Share Save
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