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ANP32E drives vulnerability to ATR inhibitors by inducing R-loops-dependent transcription replication conflicts in triple negative breast cancer Lago, Sara; Poli, Vittoria; Fol, Lisa; Botteon, Mattia; Busi, Federica; Turdo, Alice; Gaggianesi, Miriam; Ciani, Yari; D'Amato, Giacomo; Fagnocchi, Luca; Fasciani, Alessandra; Demichelis, Francesca; Todaro, Matilde Share Save
Plasma AR Alterations and Timing of Intensified Hormone Treatment for Prostate Cancer. the STAMPEDE Phase 3 Randomized Clinical Trial Leone, Gianmarco; Orlando, Francesco; Dutey-Magni, Peter; Vainauskas, Osvaldas; Grist, Emily; Ciani, Yari; Lall, Sharanpreet; Thakali, Suparna; Wingate, Anna; Wetterskog, Daniel; Sachdeva, Ashwin; Sydes, Matthew R.; Mcphail, Neil; Sreenivasan, Thiagarajan; O'Sullivan, Joe M.; Clarke, Noel W.; Parmar, Mahesh K. B.; Brown, Louise C.; James, Nicholas D.; Demichelis, Francesca; STAMPEDE collaborators Share Save
Liquid Biopsy in Progressing Prostate Cancer Patients Starting Docetaxel with or Without Enzalutamide: A Biomarker Study of the PRESIDE Phase 3b Trial Ruiz-Vico, Maria; Wetterskog, Daniel; Orlando, Francesco; Thakali, Suparna; Wingate, Anna; Jayaram, Anuradha; Cremaschi, Paolo; Vainauskas, Osvaldas; Brighi, Nicole; Castellano-Gauna, Daniel; Astrom, Lennart; Matveev, Vsevolod B.; Bracarda, Sergio; Esen, Adil; Feyerabend, Susan; Senkus, Elzbieta; Piqueras, Marta Lopez-Brea; Gupta, Santosh; Wenstrup, Rick; Boysen, Gunther; Martins, Karla; Iwata, Kenneth; Chowdhury, Simon; Gourgioti, Georgia; Serikoff, Alexis; Gonzalez-Billalabeitia, Enrique; Merseburger, Axel S.; Demichelis, Francesca; Attard, Gerhardt Share Save
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Sensitive tumor detection, accurate quantification, and ER subtyping using low-pass methylome of liquid biopsy samples from patients (pts) with metastatic breast cancer (mBC) Paoli, Marta; Nardone, Agostina; Galardi, Francesca; Biagioni, Chiara; Romagnoli, Dario; De Luca, Francesca; Franceschini, Gian Marco; Migliaccio, Ilenia; Pestrin, Marta; Sanna, Giuseppina; Risi, Emanuela; Livraghi, Luca; Moretti, Erica; Biganzoli, Laura; Malorni, Luca; Demichelis, Francesca; Benelli, Matteo Share Save
Plasma androgen receptor (AR) copy number gain at progression in patients randomized in the STAMPEDE phase 3 abiraterone acetate, prednisolone (AAP) and enzalutamide (ENZ) trial: An ancillary biomarker study Leone, Gianmarco; Orlando, Francesco; Thakali, Suparna; Lall, Sharanpreet; Wetterskog, Daniel; Wingate, Anna; Clarke, Noel W.; James, Nicholas D.; Demichelis, Francesca; Attard, Gerhardt Share Save
Sterile inflammation via TRPM8 RNA-dependent TLR3-NF-kB/IRF3 activation promotes antitumor immunity in prostate cancer Alaimo, Alessandro; Genovesi, Sacha; Annesi, Nicole; De Felice, Dario; Subedi, Saurav; Macchia, Alice; La Manna, Federico; Ciani, Yari; Vannuccini, Federico; Mugoni, Vera; Notarangelo, Michela; Libergoli, Michela; Broso, Francesca; Taulli, Riccardo; Ala, Ugo; Savino, Aurora; Cortese, Martina; Mirzaaghaei, Somayeh; Poli, Valeria; Bonapace, Ian Marc; Papotti, Mauro Giulio; Molinaro, Luca; Doglioni, Claudio; Caffo, Orazio; Anesi, Adriano; Nagler, Michael; Bertalot, Giovanni; Carbone, Francesco Giuseppe; Barbareschi, Mattia; Basso, Umberto; Dassi, Erik; Pizzato, Massimo; Romanel, Alessandro; Demichelis, Francesca; Kruithof-de Julio, Marianna; Lunardi, Andrea Share Save
Noninvasive Detection of Neuroendocrine Prostate Cancer through Targeted Cell-free DNA Methylation Franceschini, Gian Marco; Quaini, Orsetta; Mizuno, Kei; Orlando, Francesco; Ciani, Yari; Ku, Sheng-Yu; Sigouros, Michael; Rothmann, Emily; Alonso, Alicia; Benelli, Matteo; Nardella, Caterina; Auh, Joonghoon; Freeman, Dory; Hanratty, Brian; Adil, Mohamed; Elemento, Olivier; Tagawa, Scott T.; Feng, Felix Y.; Caffo, Orazio; Buttigliero, Consuelo; Basso, Umberto; Nelson, Peter S.; Corey, Eva; Haffner, Michael C.; Attard, Gerhardt; Aparicio, Ana; Demichelis, Francesca; Beltran, Himisha Share Save
Dynamics of plasma tumour DNA and copy number alterations in advanced metastatic castration-resistant prostate cancer (mCRPC) patients treated with cabazitaxel: A prospective biomarker trial Brighi, N.; Wetterskog, D.; Gurioli, G.; Orlando, F.; Conteduca, V.; Casadei, C.; Lolli, C.; Giunta, E. F.; Bleve, S.; Vainauskas, O.; Basso, U.; Pierantoni, F.; Fornarini, G.; Mosca, A.; Nicodemo, M.; Banna, G. L.; Ulivi, P.; Demichelis, F.; De Giorgi, U. F. F.; Attard, G. Share Save
Blood based biomarkers identify metastatic castration-resistant prostate cancer (mCRPC) with the greatest benefit from continuing enzalutamide (ENZ) beyond progression in combination with docetaxel (Doc): A pre-specified biomarker study of the phase IIIb PRESIDE trial Vico, M. Ruiz; Wetterskog, D.; Thakali, S.; Orlando, F.; Jayaram, A. K.; Vainauskas, O.; Gauna, D. E. Castellano; Martins, K. D.; Iwata, K.; Gourgioti, G.; Serikoff, A.; Astrom, L.; Matveev, V.; Esen, A. A.; Feyerabend, S.; Senkus-Konefka, E.; Gupta, S.; Merseburger, A. S.; Demichelis, F.; Attard, G. Share Save
Bladder cancer organoids as a functional system to model different disease stages and therapy response Minoli, Martina; Cantore, Thomas; Hanhart, Daniel; Kiener, Mirjam; Fedrizzi, Tarcisio; La Manna, Federico; Karkampouna, Sofia; Chouvardas, Panagiotis; Genitsch, Vera; Rodriguez-Calero, Antonio; Comperat, Eva; Klima, Irena; Gasperini, Paola; Kiss, Bernhard; Seiler, Roland; Demichelis, Francesca; Thalmann, George N.; Kruithof-de Julio, Marianna Share Save
Bladder cancer organoids as a functional system to model different disease stages and therapy response Minoli, Martina; Cantore, Thomas; Hanhart, Daniel; Kiener, Mirjam; Fedrizzi, Tarcisio; La Manna, Federico; Karkampouna, Sofia; Chouvardas, Panagiotis; Genitsch, Vera; Rodriguez-Calero, Jose Antonio; Comperat, Eva; Klima, Irena; Gasperini, Paola; Kiss, Bernhard; Seiler-Blarer, Roland; Demichelis, Francesca; Thalmann, George N.; Julio, Marianna Kruithof-De Share Save
MIMESIS: minimal DNA-methylation signatures to quantify and classify tumor signals in tissue and cell-free DNA samples Romagnoli, Dario; Nardone, Agostina; Galardi, Francesca; Paoli, Marta; De Luca, Francesca; Biagioni, Chiara; Franceschini, Gian Marco; Pestrin, Marta; Sanna, Giuseppina; Moretti, Erica; Demichelis, Francesca; Migliaccio, Ilenia; Biganzoli, Laura; Malorni, Luca; Benelli, Matteo Share Save
CHD8 suppression impacts on histone H3 lysine 36 trimethylation and alters RNA alternative splicing Kerschbamer, Emanuela; Arnoldi, Michele; Tripathi, Takshashila; Pellegrini, Miguel; Maturi, Samuele; Erdin, Serkan; Salviato, Elisa; Di Leva, Francesca; Sebestyen, Endre; Dassi, Erik; Zarantonello, Giulia; Benelli, Matteo; Campos, Eric; Basson, M. Albert; Gusella, James F.; Gustincich, Stefano; Piazza, Silvano; Demichelis, Francesca; Talkowski, Michael E.; Ferrari, Francesco; Biagioli, Marta Share Save
ETS-related gene (ERG) undermines genome stability in mouse prostate progenitors via Gsk3β dependent Nkx3.1 degradation Lorenzoni, Marco; De Felice, Dario; Beccaceci, Giulia; Di Donato, Giorgia; Foletto, Veronica; Genovesi, Sacha; Bertossi, Arianna; Cambuli, Francesco; Lorenzin, Francesca; Savino, Aurora; Avalle, Lidia; Cimadamore, Alessia; Montironi, Rodolfo; Weber, Veronica; Carbone, Francesco Giuseppe; Barbareschi, Mattia; Demichelis, Francesca; Romanel, Alessandro; Poli, Valeria; Del Sal, Giannino; Kruithof-de Julio, Marianna; Gaspari, Marco; Alaimo, Alessandro; Lunardi, Andrea Share Save
Comparative genomics of primary prostate cancer and paired metastases: insights from 12 molecular case studies Cyrta, Joanna; Prandi, Davide; Arora, Arshi; Hovelson, Daniel H.; Sboner, Andrea; Rodriguez, Antonio; Fedrizzi, Tarcisio; Beltran, Himisha; Robinson, Dan R.; Gopalan, Anuradha; True, Lawrence; Nelson, Peter S.; Robinson, Brian D.; Mosquera, Juan Miguel; Tomlins, Scott A.; Shen, Ronglai; Demichelis, Francesca; Rubin, Mark A. Share Save
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