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H3G34-MUTANT DIFFUSE HEMISPHERIC GLIOMAS CONTAIN CELLULAR NICHES OF GABAERGIC INTERNEURON-LIKE CELLS WITH DUAL FREQUENCY AUTONOMOUS RHYTHMIC CALCIUM ACTIVITY Cruzeiro, Gustavo Alencastro Veiga; Buhse, Johann; Cascio, Costanza Lo; Neyazi, Sina; Katiyar, Shashank; Tabatabai, Kuscha; Taylor, Kathryn; De Biagi Jr, Carlos Alberto Oliveira; Haase, Rebecca; Sarwnow, Katharina; Venkataramani, Varun; Liu, Ilon; Huang, Kun; Murphy, Maria Pazyra; Schuller, Ulrich; Segal, Rosalind; Tang, Xin; Monje, Michelle; Filbin, Mariella Share Save
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Dissecting the neuroprotective interaction between the BH4 domain of BCL-w and the IP3 receptor Tang, Sophia X.; Camara, Christina M.; Franco, Joy A.; Pazyra-Murphy, Maria F.; Li, Yihang; Godes, Marina; Moyer, Benjamin M.; Bird, Gregory H.; Segal, Rosalind A.; Walensky, Loren D. Share Save
Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastoma Tsiami, Foteini; Lago, Chiara; Pozza, Noemi; Piccioni, Federica; Zhao, Xuesong; Luelsberg, Fabienne; Root, David E.; Tiberi, Luca; Kool, Marcel; Schittenhelm, Jens; Bandopadhayay, Pratiti; Segal, Rosalind A.; Tabatabai, Ghazaleh; Merk, Daniel J. Share Save
THE GABAERGIC INTERNEURONAL AND NEURAL PROGENITOR LINEAGE OF THE DIFFUSE HEMISPHERIC GLIOMA, H3 G34-MUTANT, SHOW CALCIUM EVENTS IN THE FORM OF INTERCELLULAR WAVES AND SPONTANEOUS ELECTRICAL ACTIVITY Cruzeiro, Gustavo Alencastro Veiga; Cascio, Costanza Lo; Neyazi, Sina; Biagi Jr, Carlos Alberto Oliveira; Haase, Rebecca; Nascimento, Andrezza; Frederico, Stephen Charles; Sarnow, Katharina; Venkataramani, Varun; Liu, Ilon; Huang, Kun; Tang, Xin; Segal, Rosalind; Monje, Michelle; Filbin, Mariella Share Save
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A Benzarone Derivative Inhibits EYA to Suppress Tumor Growth in SHH Medulloblastoma Hwang, Grace H.; Pazyra-Murphy, Maria F.; Seo, Hyuk-Soo; Dhe-Paganon, Sirano; Stopka, Sylwia A.; Dipiazza, Marina; Sutter, Nizhoni; Gero, Thomas W.; Volkert, Alison; Ombelets, Lincoln; Dittemore, Georgia; Rees, Matthew G.; Ronan, Melissa M.; Roth, Jennifer A.; Agar, Nathalie Y. R.; Scott, David A.; Segal, Rosalind A. Share Save
Developmental basis of SHH medulloblastoma heterogeneity Gold, Maxwell P.; Ong, Winnie; Masteller, Andrew M.; Ghasemi, David R.; Galindo, Julie Anne; Park, Noel R.; Huynh, Nhan C.; Donde, Aneesh; Pister, Veronika; Saurez, Raul A.; Vladoiu, Maria C.; Hwang, Grace H.; Eisemann, Tanja; Donovan, Laura K.; Walker, Adam D.; Benetatos, Joseph; Dufour, Christelle; Garzia, Livia; Segal, Rosalind A.; Wechsler-Reya, Robert J.; Mesirov, Jill P.; Korshunov, Andrey; Pajtler, Kristian W.; Pomeroy, Scott L.; Ayrault, Olivier; Davidson, Shawn M.; Cotter, Jennifer A.; Taylor, Michael D.; Fraenkel, Ernest Share Save
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TMEM161B regulates cerebral cortical gyration, Sonic Hedgehog signaling, and ciliary structure in the developing central nervous system Akula, Shyam K.; Marciano, Jack H.; Lim, Youngshin; Exposito-Alonso, David; Hylton, Norma K.; Hwang, Grace H.; Neil, Jennifer E.; Dominado, Nicole; Bunton-Stasyshyn, Rosie K.; Song, Janet H. T.; Talukdar, Maya; Schmid, Aloisia; Teboul, Lydia; Mo, Alisa; Shin, Taehwan; Finander, Benjamin; Beck, Samantha G.; Yeh, Rebecca C.; Otani, Aoi; Qian, Xuyu; DeGennaro, Ellen M.; Alkuraya, Fowzan S.; Maddirevula, Sateesh; Cascino, Gregory D.; Giannini, Caterina; Undiagnosed Diseases Network, Lindsay C.; Burrage, Lindsay C.; Rosenfield, Jill A.; Ketkar, Shamika; Clark, Gary D.; Bacino, Carlos; Lewis, Richard A.; Segal, Rosalind A.; Bazan, J. Fernando; Smith, Kelly A.; Golden, Jeffrey A.; Cho, Ginam; Walsh, Christopher A. Share Save
An affinity for brainstem microglia in pediatric high-grade gliomas of brainstem origin Zats, Liat Peretz; Ahmad, Labiba; Casden, Natania; Lee, Meelim J.; Belzer, Vitali; Adato, Orit; Bar Cohen, Shaked; Ko, Seung-Hyun B.; Filbin, Mariella G.; Unger, Ron; Lauffenburger, Douglas A.; Segal, Rosalind A.; Behar, Oded Share Save
Synthetic extracellular matrices and astrocytes provide a supportive microenvironment for the cultivation and investigation of primary pediatric gliomas Rota, Christopher M.; Brown, Alexander T.; Addleson, Emily; Ives, Clara; Trumper, Ella; Pelton, Kristine; Teh, Wei Pin; Schniederjan, Matthew J.; Castellino, Robert Craig; Buhrlage, Sara; Lauffenburger, Douglas A.; Ligon, Keith L.; Griffith, Linda G.; Segal, Rosalind A. Share Save
Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN Li, Yihang; Pazyra-Murphy, Maria F.; Avizonis, Daina; Russo, Mariana de Sa Tavares; Tang, Sophia; Chen, Chiung-Ya; Hsueh, Yi-Ping; Bergholz, Johann S.; Jiang, Tao; Zhao, Jean J.; Zhu, Jian; Ko, Kwang Woo; Milbrandt, Jeffrey; DiAntonio, Aaron; Segal, Rosalind A. Share Save
Diversity of developing peripheral glia revealed by single-cell RNA sequencing Tasdemir-Yilmaz, Ozge E.; Druckenbrod, Noah R.; Olukoya, Olubusola O.; Dong, Weixiu; Yung, Andrea R.; Bastille, Isle; Pazyra-Murphy, Maria F.; Sitko, Austen A.; Hale, Evan B.; Vigneau, Sebastien; Gimelbrant, Alexander A.; Kharchenko, Peter, V; Goodrich, Lisa, V; Segal, Rosalind A. Share Save
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Binding and transport of SFPQ-RNA granules by KIF5A/KLC1 motors promotes axon survival Fukuda, Yusuke; Pazyra-Murphy, Maria F.; Silagi, Elizabeth S.; Tasdemir-Yilmaz, Ozge E.; Li, Yihang; Rose, Lillian; Yeoh, Zoe C.; Vangos, Nicholas E.; Geffken, Ezekiel A.; Seo, Hyuk-Soo; Adelmant, Guillaume; Bird, Gregory H.; Walensky, Loren D.; Marto, Jarrod A.; Dhe-Paganon, Sirano; Segal, Rosalind A. Share Save
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