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SaveAppoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis (vol 87, pg 963, 2015)
Zhao, Yingjun; Tseng, I. -Chu; Heyser, Charles J.; Rockenstein, Edward; Mante, Michael; Adame, Anthony; Zheng, Qiuyang; Huang, Timothy; Wang, Xin; Arslan, Pharhad E.; Chakrabarty, Paramita; Wu, Chengbiao; Bu, Guojun; Mobley, William C.; Zhang, Yun-wu; St George-Hyslop, Peter; Masliah, Eliezer; Fraser, Paul; Xu, Huaxi Share Save P-tau217 correlates with neurodegeneration in Alzheimer's disease, and targeting p-tau217 with immunotherapy ameliorates murine tauopathyZhang, Denghong; Zhang, Wei; Ming, Chen; Gao, Xuheng; Yuan, Huilong; Lin, Xiaojie; Mao, Xinru; Wang, Chunping; Guo, Xiaoyi; Du, Ying; Shao, Lin; Yang, Renzhi; Lin, Zhihao; Wu, Xilin; Huang, Timothy Y.; Wang, Zhanxiang; Zhang, Yun-wu; Xu, Huaxi; Zhao, Yingjun Share Save Minocycline protects against microgliopathy in a Csf1r haplo-insufficient mouse model of adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP)Li, Xin; Hu, Banglian; Guan, Xiaoyan; Wang, Ziwei; Zhou, Yuhang; Sun, Hao; Zhang, Xian; Li, Yanfang; Huang, Xiaohua; Zhao, Yingjun; Wang, Xin; Xu, Huaxi; Zhang, Yun-Wu; Wang, Zhanxiang; Zheng, Honghua Share Save Dietary intake of α-ketoglutarate ameliorates α-synuclein pathology in mouse models of Parkinson's diseaseZhang, Wenlong; Ding, Liuyan; Zhang, Mengran; Zheng, Shaohui; Ma, Runfang; Gong, Junwei; Mao, Hengxu; Xu, Huaxi; Xu, Pingyi; Zhang, Yunlong Share Save Cntnap4 partial deficiency exacerbates α-synuclein pathology through astrocyte-microglia C3-C3aR pathwayZhang, Wenlong; Ding, Liuyan; Chen, Huaqing; Zhang, Mengran; Ma, Runfang; Zheng, Shaohui; Gong, Junwei; Zhang, Zhiling; Xu, Huaxi; Xu, Pingyi; Zhang, Yunlong Share Save Transcriptional regulation of PEN-2, a key component of the γ-secretase complex, by CREBWang, RS; Zhang, YW; Sun, P; Liu, RZ; Zhang, X; Zhang, X; Xia, K; Xia, JH; Xu, HX; Zhang, ZH Share Save Loss of RAB39B does not alter MPTP-induced Parkinson's disease-like phenotypes in miceWang, Zijie; Yang, Dingting; Jiang, Yiru; Wang, Yong; Niu, Mengxi; Wang, Chong; Luo, Hong; Xu, Huaxi; Li, Jingwen; Zhang, Yun-wu; Zhang, Xian Share Save Microglial hexokinase 2 deficiency increases ATP generation through lipid metabolism leading to β-amyloid clearance (vol 4, pg 1287, 2022)Leng, Lige; Yuan, Ziqi; Pan, Ruiyuan; Su, Xiao; Wang, Han; Xue, Jin; Zhuang, Kai; Gao, Ju; Chen, Zhenlei; Lin, Hui; Xie, Wenting; Li, Huifang; Chen, Zhenyi; Ren, Keke; Zhang, Xiao; Wang, Wenting; Jin, Zi-Bing; Wu, Shengxi; Wang, Xinglong; Yuan, Zengqiang; Xu, Huaxi; Chow, Hei-Man; Zhang, Jie Share Save Pedigree-based study to identify GOLGB1 as a risk gene for bipolar disorderLiu, Fa-rong; Zhou, Yunqiang; Wang, Yong; Huang, Ling-ling; Zhang, Xian; Luo, Hong; Wu, Su-ying; Lyu, Hai-yan; Huang, Li-huan; Xu, Huaxi; Zhang, Yun-wu Share Save A tetravalent TREM2 agonistic antibody reduced amyloid pathology in a mouse model of Alzheimer's diseaseZhao, Peng; Xu, Yuanzhong; Jiang, Lulin; Fan, Xuejun; Li, Leike; Li, Xin; Arase, Hisashi; Zhao, Yingjun; Cao, Wei; Zheng, Hui; Xu, Huaxi; Tong, Qingchun; Zhang, Ningyan; An, Zhiqiang Share Save Trem2 deletion enhances tau dispersion and pathology through microglia exosomesZhu, Bing; Liu, Yan; Hwang, Spring; Archuleta, Kailey; Huang, Huijie; Campos, Alex; Murad, Rabi; Pina-Crespo, Juan; Xu, Huaxi; Huang, Timothy Y. Share Save Share Save LILRB2-mediated TREM2 signaling inhibition suppresses microglia functionsZhao, Peng; Xu, Yuanzhong; Jiang, Lu-Lin; Fan, Xuejun; Ku, Zhiqiang; Li, Leike; Liu, Xiaoye; Deng, Mi; Arase, Hisashi; Zhu, Jay-Jiguang; Huang, Timothy Y.; Zhao, Yingjun; Zhang, Chengcheng; Xu, Huaxi; Tong, Qingchun; Zhang, Ningyan; An, Zhiqiang Share Save Share Save APOE-ε4 modulates the association among plasma Aβ42/Aβ40, vascular diseases, neurodegeneration and cognitive decline in non-demented elderly adultsShi, Dai; Xie, Siwei; Li, Anqi; Wang, Qingyong; Guo, Hongbo; Han, Ying; Xu, Huaxi; Gan, Wen-Biao; Zhang, Lei; Guo, Tengfei Share Save Metabolic reprogramming in astrocytes results in neuronal dysfunction in intellectual disabilityZhang, Haibin; Zheng, Qiuyang; Guo, Tiantian; Zhang, Shijun; Zheng, Shuang; Wang, Ruimin; Deng, Qingfang; Yang, Guowei; Zhang, Shuo; Tang, Linxin; Qi, Qiuping; Zhu, Lin; Zhang, Xiu-Fang; Luo, Hong; Zhang, Xian; Sun, Hao; Gao, Yue; Zhang, Hongfeng; Zhou, Ying; Han, Aidong; Zhang, Chen-Song; Xu, Huaxi; Wang, Xin Share Save USP25 inhibition ameliorates Alzheimer's pathology through the regulation of APP processing and Aβ generationZheng, Qiuyang; Song, Beibei; Li, Guilin; Cai, Fang; Wu, Meiling; Zhao, Yingjun; Jiang, LuLin; Guo, Tiantian; Shen, Mingyu; Hou, Huan; Zhou, Ying; Zhao, Yini; Di, Anjie; Zhang, Lishan; Zeng, Fanwei; Zhang, Xiu-Fang; Luo, Hong; Zhang, Xian; Zhang, Hongfeng; Zeng, Zhiping; Huang, Timothy Y.; Dong, Chen; Qing, Hong; Zhang, Yun; Zhang, Qing; Wang, Xu; Wu, Yili; Xu, Huaxi; Song, Weihon; Wang, Xin Share Save Identification of the minimal active soluble TREM2 sequence for modulating microglial phenotypes and amyloid pathologySheng, Xuan; Yao, Yunling; Huang, Ruizhi; Xu, Ying; Zhu, Yifei; Chen, Linting; Zhang, Lianshuai; Wang, Wanbing; Zhuo, Rengong; Can, Dan; Chang, Che-Feng; Zhang, Yun-Wu; Xu, Huaxi; Bu, Guojun; Zhong, Li; Chen, Xiao-Fen Share Save Share Save 
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