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Inclusion of a retroviral protease enhances the immunogenicity of VLP-forming mRNA vaccines against HIV-1 or SARS-CoV-2 in mice Zhang, Peng; Singh, Mamta; Becker, Vada A.; Croft, Jacob; Tsybovsky, Yaroslav; Gopan, Vinay; Seo, Yuna; Liu, Qingbo; Rogers, Denise; Miao, Huiyi; Lin, Yin; Rogan, Daniel; Shields, Courtney; Elbashir, Sayda M.; Calabrese, Samantha; Renzi, Isabella; Preznyak, Vladimir; Narayanan, Elizabeth; Stewart-Jones, Guillaume; Himansu, Sunny; Connors, Mark; Lee, Kelly; Carfi, Andrea; Lusso, Paolo Share Save
mRNA-1273 vaccines adapted to JN.1 or KP.2 elicit cross-neutralizing responses against the JN.1 sublineages of SARS-CoV-2 in mice Lee, Diana Wing; Nasir, Arshan; Elbashir, Sayda; Jani, Hardik; Speidel, Tessa; Gorrie, Amy; Berrueta, Daniela Montes; Martin, Philippa; Tan, Swan; Hou, Yixuan Jacob; Hardcastle, Kath; Edwards, Darin; Wu, Kai; Carfi, Andrea; Budigi, Yadunanda Share Save
Mpox mRNA-1769 vaccine inhibits orthopoxvirus replication at intranasal, intrarectal, and cutaneous sites of inoculation Cotter, Catherine A.; Ignacio, Maxinne A.; Americo, Jeffrey L.; Earl, Patricia L.; Mucker, Eric M.; Frey, Tiffany R.; Carfi, Andrea; Hooper, Jay W.; Freyn, Alec W.; Moss, Bernard Share Save
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Multivalent mRNA-DTP vaccines are immunogenic and provide protection from Bordetella pertussis challenge in mice Wolf, M. Allison; O'Hara, Joanne M.; Bitzer, Graham J.; Narayanan, Elisabeth; Boehm, Dylan T.; Bevere, Justin R.; Dejong, Megan A.; Hall, Jesse M.; Wong, Ting Y.; Falcone, Samantha; Deal, Cailin E.; Richards, Angelene; Green, Shannon; Nguyen, Brenda; King, Emily; Ogega, Clinton; Russo, Lisa; Sen-Kilic, Emel; Plante, Obadiah; Himansu, Sunny; Barbier, Mariette; Carfi, Andrea; Damron, F. Heath Share Save
mRNA-LNP prime boost evolves precursors toward VRC01-like broadly neutralizing antibodies in preclinical humanized mouse models Wang, Xuesong; Cottrell, Christopher A.; Hu, Xiaozhen; Ray, Rashmi; Bottermann, Maria; Villavicencio, Paula Maldonado; Yan, Yu; Xie, Zhenfei; Warner, John E.; Ellis-Pugh, Jordan Renae; Kalyuzhniy, Oleksandr; Liguori, Alessia; Willis, Jordan R.; Menis, Sergey; Raemisch, Sebastian; Eskandarzadeh, Saman; Kubitz, Michael; Tingle, Ryan; Phelps, Nicole; Groschel, Bettina; Himansu, Sunny; Carfi, Andrea; Kirsch, Kathrin H.; Weldon, Stephanie R.; Nair, Usha; Schief, William R.; Batista, Facundo D. Share Save
Characterization of humoral and cellular immunologic responses to an mRNA-based human cytomegalovirus vaccine from a phase 1 trial of healthy adults Wu, Kai; Hou, Yixuan Jacob; Makrinos, Dan; Liu, Runxia; Zhu, Alex; Koch, Matthew; Yu, Wen-Han; Paila, Yamuna D.; Chandramouli, Sumana; Panther, Lori; Henry, Carole; Dipiazza, Anthony; Carfi, Andrea Share Save
Safety and Immunogenicity of a Messenger RNA-Based Cytomegalovirus Vaccine in Healthy Adults: Results From a Phase 1 Randomized Clinical Trial Fierro, Carlos; Brune, Daniel; Shaw, Marian; Schwartz, Howard; Knightly, Conor; Lin, Jiang; Carfi, Andrea; Natenshon, Andrew; Kalidindi, Shiva; Reuter, Caroline; Miller, Jacqueline; Panther, Lori Share Save
Human Cytomegalovirus mRNA-1647 Vaccine Candidate Elicits Potent and Broad Neutralization and Higher Antibody-Dependent Cellular Cytotoxicity Responses Than the gB/MF59 Vaccine Hu, Xintao; Karthigeyan, Krithika P.; Herbek, Savannah; Valencia, Sarah M.; Jenks, Jennifer A.; Webster, Helen; Miller, Itzayana G.; Connors, Megan; Pollara, Justin; Andy, Caroline; Gerber, Linda M.; Walter, Emmanuel B.; Edwards, Kathryn M.; Bernstein, David, I; Hou, Jacob; Koch, Matthew; Panther, Lori; Carfi, Andrea; Wu, Kai; Permar, Sallie R. Share Save
Interaction dynamics between innate and adaptive immune cells responding to SARS-CoV-2 vaccination in non-human primates Schramm, Chaim A.; Moon, Damee; Peyton, Lowrey; Lima, Noemia S.; Wake, Christian; Boswell, Kristin L.; Henry, Amy R.; Laboune, Farida; Ambrozak, David; Darko, Samuel W.; Teng, I-Ting; Foulds, Kathryn E.; Carfi, Andrea; Edwards, Darin K.; Kwong, Peter D.; Koup, Richard A.; Seder, Robert A.; Douek, Daniel C. Share Save
An mRNA-based platform for the delivery of pathogen-specific IgA into mucosal secretions Deal, Cailin E.; Richards, Angelene F.; Yeung, Tracy; Maron, Max J.; Wang, Ziqiu; Lai, Yen-Ting; Fritz, Brian R.; Himansu, Sunny; Narayanan, Elisabeth; Liu, Ding; Koleva, Rositsa; Licht, Stuart; Hsiao, Chiaowen J.; Rajlic, Ivana L.; Koch, Hillary; Kleyman, Michael; Pulse, Mark E.; Weiss, William J.; Doering, Jennifer E.; Lindberg, Samantha K.; Mantis, Nicholas J.; Carfi, Andrea; Plante, Obadiah J. Share Save
An mpox virus mRNA-lipid nanoparticle vaccine confers protection against lethal orthopoxviral challenge Freyn, Alec W.; Atyeo, Caroline; Earl, Patricia L.; Americo, Jeffrey L.; Chuang, Gwo-Yu; Natarajan, Harini; Frey, Tiffany R.; Gall, Jason G.; Moliva, Juan I.; Hunegnaw, Ruth; Arunkumar, Guha Asthagiri; Ogega, Clinton O.; Nasir, Arshan; Santos, Genesis; Levin, Rafael H.; Meni, Anusha; Jorquera, Patricia A.; Bennett, Hamilton; Johnson, Joshua A.; Durney, Michael A.; Stewart-Jones, Guillaume; Hooper, Jay W.; Colpitts, Tonya M.; Alter, Galit; Sullivan, Nancy J.; Carfi, Andrea; Moss, Bernard Share Save
Intranasal mRNA-LNP vaccination protects hamsters from SARS-CoV-2 infection Vaca, Gabriela Baldeon; Meyer, Michelle; Cadete, Ana; Hsiao, Chiaowen Joyce; Golding, Anne; Jeon, Albert; Jacquinet, Eric; Azcue, Emily; Guan, Chenxia Monica; Sanchez-Felix, Xavier; Pietzsch, Colette A.; Mire, Chad E.; Hyde, Matthew A.; Comeaux, Margaret E.; Williams, Julie M.; Sung, Jean C.; Carfi, Andrea; Edwards, Darin K.; Bukreyev, Alexander; Bahl, Kapil Share Save
Domain-based mRNA vaccines encoding spike protein N-terminal and receptor binding domains confer protection against SARS-CoV-2 Stewart-Jones, Guillaume B. E.; Elbashir, Sayda M.; Wu, Kai; Lee, Diana; Renzi, Isabella; Ying, Baoling; Koch, Matthew; Sein, Caralyn E.; Choi, Angela; Whitener, Bradley; Garcia-Dominguez, Dario; Henry, Carole; Woods, Angela; Ma, LingZhi; Montes Berrueta, Daniela; Avena, Laura E.; Quinones, Julian; Falcone, Samantha; Hsiao, Chiaowen J.; Scheaffer, Suzanne M.; Thackray, Larissa B.; White, Phil; Diamond, Michael S.; Edwards, Darin K.; Carfi, Andrea Share Save
A Lassa virus mRNA vaccine confers protection but does not require neutralizing antibody in a guinea pig model of infection Ronk, Adam J.; Lloyd, Nicole M.; Zhang, Min; Atyeo, Caroline; Perrett, Hailee R.; Mire, Chad E.; Hastie, Kathryn M.; Sanders, Rogier W.; Brouwer, Philip J. M.; Saphire, Erica Olmann; Ward, Andrew B.; Ksiazek, Thomas G.; Alvarez Moreno, Juan Carlos; Thaker, Harshwardhan M.; Alter, Galit; Himansu, Sunny; Carfi, Andrea; Bukreyev, Alexander Share Save
Increased neutralization potency and breadth elicited by a SARS-CoV-2 mRNA vaccine forming virus- like particles Zhang, Peng; Falcone, Samantha; Tsybovsky, Yaroslav; Singh, Mamta; Gopan, Vinay; Miao, Huiyi; Seo, Yuna; Rogers, Denise; Renzi, Isabella; Lai, Yen-Ting; Narayanan, Elisabeth; Stewart-Jones, Guillaume; Himansu, Sunny; Carfi, Andrea; Fauci, Anthony S.; Lusso, Paolo Share Save
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