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Systematic loss-of-function screens identify pathway-specific functional circular RNAs Liu, Ling; Neve, Matthew; Perlaza-Jimenez, Laura; Xi, Xinqi; Purcell, Jacob; Hawdon, Azelle; Conn, Simon J.; Zenker, Jennifer; Tamayo, Pablo; Goodall, Gregory J.; Rosenbluh, Joseph Share Save
MULTI-OMICS AND FUNCTIONAL PRECISION MEDICINE FOR NEWLY DIAGNOSED AND RECURRENT PEDIATRIC CENTRAL NERVOUS SYSTEM TUMORS Crawford, John R.; Lo, Yan Yuen; Pagadala, Meghana S.; Chapman, Owen S.; Sridhar, Sunita; Juarez, Edwin F.; Tzaridis, Theophilos; Chau, Lianne Q.; Wang, Jun; Eisemann, Tanja; Masihi, Meher Beigi; Chambers, Kendall R.; Dixit, Deobrat; Koubourli, Daphne; Larson, Jon D.; Guidugli, Lucia; Hammer, Monia; Wong, Terence; Abdullaev, Zied; Quezado, Martha; Martins, Timothy J.; Reich, Michael; Sears, Timothy; Hobbs, Charlotte; Kingsmore, Stephen F.; Levy, Michael L.; Gonda, David; Malicki, Denise M.; Snuderl, Matija; Becker, Pamela S.; Tamayo, Pablo; Elster, Jennifer D.; Aldape, Kenneth; Carter, Hannah; Paul, Megan R.; Mesirov, Jill P.; Chavez, Lukas; Wechsler-Reya, Robert J. Share Save
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Inferring cellular and molecular processes in single-cell data with non-negative matrix factorization using Python, R and GenePattern Notebook implementations of CoGAPS Johnson, Jeanette A. I.; Tsang, Ashley P.; Mitchell, Jacob T.; Zhou, David L.; Bowden, Julia; Davis-Marcisak, Emily; Sherman, Thomas; Liefeld, Ted; Loth, Melanie; Goff, Loyal A.; Zimmerman, Jacquelyn W.; Kinny-Koester, Ben; Jaffee, Elizabeth M.; Tamayo, Pablo; Mesirov, Jill P.; Reich, Michael; Fertig, Elana J.; Stein-O'Brien, Genevieve L. Share Save
Syk Inhibition Reprograms Tumor-Associated Macrophages and Overcomes Gemcitabine-Induced Immunosuppression in Pancreatic Ductal Adenocarcinoma Rohila, Deepak; Park, In Hwan; Pham, Timothy, V; Weitz, Jonathan; de Mendoza, Tatiana Hurtado; Madheswaran, Suresh; Ishfaq, Mehreen; Beaman, Cooper; Tapia, Elisabette; Sun, Siming; Patel, Jay; Tamayo, Pablo; Lowy, Andrew M.; Joshi, Shweta Share Save
Multimodal perturbation analyses of cyclin-dependent kinases reveal a network of synthetic lethalities associated with cell-cycle regulation and transcriptional regulation Ford, Kyle; Munson, Brenton P.; Fong, Samson H.; Panwala, Rebecca; Chu, Wai Keung; Rainaldi, Joseph; Plongthongkum, Nongluk; Arunachalam, Vinayagam; Kostrowicki, Jarek; Meluzzi, Dario; Kreisberg, Jason F.; Jensen-Pergakes, Kristen; VanArsdale, Todd; Paul, Thomas; Tamayo, Pablo; Zhang, Kun; Bienkowska, Jadwiga; Mali, Prashant; Ideker, Trey Share Save
Differential regulation of TNFα and IL-6 expression contributes to immune evasion in prostate cancer Deichaite, Ida; Sears, Timothy J.; Sutton, Leisa; Rebibo, Daniel; Morgan, Kylie; Nelson, Tyler; Rose, Brent; Tamayo, Pablo; Ferrara, Napoleone; Asimakopoulos, Fotis; Carter, Hannah Share Save
CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity Bernareggi, Davide; Xie, Qi; Prager, Briana C.; Yun, Jiyoung; Cruz, Luisjesus S.; Pham, Timothy, V; Kim, William; Lee, Xiqing; Coffey, Michael; Zalfa, Cristina; Azmoon, Pardis; Zhu, Huang; Tamayo, Pablo; Rich, Jeremy N.; Kaufman, Dan S. Share Save
Human induced pluripotent stem cell-derived macrophages ameliorate liver fibrosis Pouyanfard, Somayeh; Meshgin, Nairika; Cruz, Luisjesus S.; Diggle, Karin; Hashemi, Hamidreza; Pham, Timothy, V; Fierro, Manuel; Tamayo, Pablo; Fanjul, Andrea; Kisseleva, Tatiana; Kaufman, Dan S. Share Save
KITlow Cells Mediate Imatinib Resistance in Gastrointestinal Stromal Tumor Banerjee, Sudeep; Yoon, Hyunho; Ting, Stephanie; Tang, Chih-Min; Yebra, Mayra; Wenzel, Alexander T.; Yeerna, Huwate; Mesirov, Jill P.; Wechsler-Reya, Robert J.; Tamayo, Pablo; Sicklick, Jason K. Share Save
TORC1/2 kinase inhibition depletes glutathione and synergizes with carboplatin to suppress the growth of MYC-driven medulloblastoma Maynard, Rachael E.; Poore, Brad; Hanaford, Allison R.; Pham, Khoa; James, Madison; Alt, Jesse; Park, Youngran; Slusher, Barbara S.; Tamayo, Pablo; Mesirov, Jill; Archer, Tenley C.; Pomeroy, Scott L.; Eberhart, Charles G.; Raabe, Eric H. Share Save
SPT6 promotes epidermal differentiation and blockade of an intestinal-like phenotype through control of transcriptional elongation Li, Jingting; Xu, Xiaojun; Tiwari, Manisha; Chen, Yifang; Fuller, Mackenzie; Bansal, Varun; Tamayo, Pablo; Das, Soumita; Ghosh, Pradipta; Sen, George L. Share Save
Functional Precision Medicine Identifies New Therapeutic Candidates for Medulloblastoma Rusert, Jessica M.; Juarez, Edwin F.; Brabetz, Sebastian; Jensen, James; Garancher, Alexandra; Chau, Lianne Q.; Tacheva-Grigorova, Silvia K.; Wahab, Sameerah; Udaka, Yoko T.; Finlay, Darren; Seker-Cin, Huriye; Reardon, Brendan; Groebner, Susanne; Serrano, Jonathan; Ecker, Jonas; Qi, Lin; Kogiso, Mari; Du, Yuchen; Baxter, Patricia A.; Henderson, Jacob J.; Berens, Michael E.; Vuori, Kristiina; Milde, Till; Cho, Yoon-Jae; Li, Xiao-Nan; Olson, James M.; Reyes, Iris; Snuderl, Matija; Wong, Terence C.; Dimmock, David P.; Nahas, Shareef A.; Malicki, Denise; Crawford, John R.; Levy, Michael L.; Van Allen, Eliezer M.; Pfister, Stefan M.; Tamayo, Pablo; Kool, Marcel; Mesirov, Jill P.; Wechsler-Reya, Robert J. Share Save
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HPV E2, E4, E5 drive alternative carcinogenic pathways in HPV positive cancers Ren, Shuling; Gaykalova, Daria A.; Guo, Theresa; Favorov, Alexander, V; Fertig, Elana J.; Tamayo, Pablo; Callejas-Valera, Juan Luis; Allevato, Mike; Gilardi, Mara; Santos, Jessica; Fukusumi, Takahito; Sakai, Akihiro; Ando, Mizuo; Sadat, Sayed; Liu, Chao; Xu, Guorong; Fisch, Kathleen M.; Wang, Zhiyong; Molinolo, Alfredo A.; Gutkind, J. Silvio; Ideker, Trey; Koch, Wayne M.; Califano, Joseph A. Share Save
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The composition of the human ribosome varies significantly in different normal and malignant tissues Panda, Anshuman; Yadav, Anupama; Yeerna, Huwate; Singh, Amartya; Biehl, Michael; Lux, Markus; Schulz, Alexander; Klecha, Tyler; Doniach, Sebastian; Khiabanian, Hossein; Ganesan, Shridar; Tamayo, Pablo; Bhanot, Gyan Share Save
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