Not logged in Share Save
NLS-binding deficient Kapβ2 reduces neurotoxicity via selective interaction with C9orf72-ALS/FTD dipeptide repeats Kim, Kevin M.; Girdhar, Amandeep; Cicardi, Maria E.; Kankate, Vaishnavi; Hayashi, Miyuki; Yang, Ruoyu; Carey, Jenny L.; Fare, Charlotte M.; Shorter, James; Cingolani, Gino; Trotti, Davide; Guo, Lin Share Save
ARID1A-BAF coordinates ZIC2 genomic occupancy for epithelial-to-mesenchymal transition in cranial neural crest specification Barnada, Samantha M.; de Gracia, Aida Giner; Morenilla-Palao, Cruz; Lopez-Cascales, Maria Teresa; Scopa, Chiara; Waltrich Jr, Francis J.; Mikkers, Harald M. M.; Cicardi, Maria Elena; Karlin, Jonathan; Trotti, Davide; Peterson, Kevin A.; Brugmann, Samantha A.; Santen, Gijs W. E.; McMahon, Steven B.; Herrera, Eloisa; Trizzino, Marco Share Save
Glucose hypometabolism prompts RAN translation and exacerbates C9orf72-related ALS/FTD phenotypes Nelson, Andrew T.; Cicardi, Maria Elena; Markandaiah, Shashirekha S.; Han, John Y. S.; Philp, Nancy J.; Welebob, Emily; Haeusler, Aaron R.; Pasinelli, Piera; Manfredi, Giovanni; Kawamata, Hibiki; Trotti, Davide Share Save
The nuclear import receptor Kapβ2 modifies neurotoxicity mediated by poly(GR) in C9orf72-linked ALS/FTD Cicardi, M. E.; Kankate, V.; Sriramoji, S.; Krishnamurthy, K.; Markandaiah, S. S.; Verdone, B. M.; Girdhar, A.; Nelson, A.; Rivas, L. B.; Boehringer, A.; Haeusler, A. R.; Pasinelli, P.; Guo, L.; Trotti, D. Share Save
EphrinB2 knockdown in cervical spinal cord preserves diaphragm innervation in a mutant SOD1 mouse model of ALS Urban, Mark W.; Charsar, Brittany A.; Heinsinger, Nicolette M.; Markandaiah, Shashirekha S.; Sprimont, Lindsay; Zhou, Wei; Brown, Eric, V; Henderson, Nathan T.; Thomas, Samantha J.; Ghosh, Biswarup; Cain, Rachel E.; Trotti, Davide; Pasinelli, Piera; Wright, Megan C.; Dalva, Matthew B.; Lepore, Angelo C. Share Save
Share Save
Loss of PML nuclear bodies in familial amyotrophic lateral sclerosis-frontotemporal dementia Antoniani, Francesco; Cimino, Marco; Mediani, Laura; Vinet, Jonathan; Verde, Enza M.; Secco, Valentina; Yamoah, Alfred; Tripathi, Priyanka; Aronica, Eleonora; Cicardi, Maria E.; Trotti, Davide; Sterneckert, Jared; Goswami, Anand; Carra, Serena Share Save
Share Save
Share Save
NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility Gleixner, Amanda M.; Verdone, Brandie Morris; Otte, Charlton G.; Anderson, Eric N.; Ramesh, Nandini; Shapiro, Olivia R.; Gale, Jenna R.; Mauna, Jocelyn C.; Mann, Jacob R.; Copley, Katie E.; Daley, Elizabeth L.; Ortega, Juan A.; Cicardi, Maria Elena; Kiskinis, Evangelos; Kofler, Julia; Pandey, Udai B.; Trotti, Davide; Donnelly, Christopher J. Share Save
Share Save
A mouse model with widespread expression of the C9orf72-linked glycine-arginine dipeptide displays non-lethal ALS/FTD-like phenotypes Verdone, Brandie Morris; Cicardi, Maria Elena; Wen, Xinmei; Sriramoji, Sindhu; Russell, Katelyn; Markandaiah, Shashirekha S.; Jensen, Brigid K.; Krishnamurthy, Karthik; Haeusler, Aaron R.; Pasinelli, Piera; Trotti, Davide Share Save
Share Save
Synaptic dysfunction induced by glycine-alanine dipeptides in C9orf72-ALS/FTD is rescued by SV2 replenishment Jensen, Brigid K.; Schuldi, Martin H.; McAvoy, Kevin; Russell, Katelyn A.; Boehringer, Ashley; Curran, Bridget M.; Krishnamurthy, Karthik; Wen, Xinmei; Westergard, Thomas; Ma, Le; Haeusler, Aaron R.; Edbauer, Dieter; Pasinelli, Piera; Trotti, Davide Share Save
Share Save
Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons Shi, Yingxiao; Lin, Shaoyu; Staats, Kim A.; Li, Yichen; Chang, Wen-Hsuan; Hung, Shu-Ting; Hendricks, Eric; Linares, Gabriel R.; Wang, Yaoming; Son, Esther Y.; Wen, Xinmei; Kisler, Kassandra; Wilkinson, Brent; Menendez, Louise; Sugawara, Tohru; Woolwine, Phillip; Huang, Mickey; Cowan, Michael J.; Ge, Brandon; Koutsodendris, Nicole; Sandor, Kaitlin P.; Komberg, Jacob; Vangoor, Vamshidhar R.; Senthilkumar, Ketharini; Hennes, Valerie; Seah, Carina; Nelson, Amy R.; Cheng, Tze-Yuan; Lee, Shih-Jong J.; August, Paul R.; Chen, Jason A.; Wisniewski, Nicholas; Hanson-Smith, Victor; Belgard, T. Grant; Zhang, Alice; Coba, Marcelo; Grunseich, Chris; Ward, Michael E.; van den Berg, Leonard H.; Pasterkamp, R. Jeroen; Trotti, Davide; Zlokovic, Berislav V.; Ichida, Justin K. Share Save
Share Save
Muscles secretion of toxic factors regulated by miR126-5P facilitate motor neuron degeneration in ALS Maimon, R.; Ionescu, A.; Bonnie, A.; Sweetat, S.; Wald-Altman, S.; Gradus, T.; Weil, M.; Behar, O.; Trotti, D.; Perlson, E. Share Save
Share Save
.png){kind=icon}
.png){kind=icon}
Not logged in.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
