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SaveShare Save KRAS mutation detection by liquid biopsy for pancreatic ductal adenocarcinoma
Yousef, Mahmoud; Yousef, Abdelrahman; Hurd, Mark W.; Pillai, Ashwathy; Chowdhury, Saikat; Snyder, Rebecca; Knafl, Mark; Lewis, Ryan L.; Roy, Paul M.; Fanaeian, Mohammad; Albarouki, Sali; Castelnovo, Luca F.; Peterson, Jennifer; Smaglo, Brandon G.; Wolff, Robert A.; Pant, Shubham; Willis, Jason; Huey, Ryan; Overman, Michael; Tzeng, Ching-Wei; Kim, Michael P.; Ikoma, Naruhiko; Maxwell, Jess E.; Katz, Matthew H. G.; Wang, Huamin; Maitra, Anirban; Koay, Eugene; Ludmir, Ethan B.; Chen, Anthony; Lopez, Camila; Ying, Haoqiang; Shen, John Paul; Zhao, Dan Share Save Targeting a chemo-induced adaptive signaling circuit confers therapeutic vulnerabilities in pancreatic cancerSaito, Yohei; Xiao, Yi; Yao, Jun; Li, Yunhai; Liu, Wendao; Yuzhalin, Arseniy E.; Shyu, Yueh-Ming; Li, Hongzhong; Yuan, Xiangliang; Li, Ping; Zhang, Qingling; Li, Ziyi; Wei, Yongkun; Yin, Xuedong; Zhao, Jun; Kariminia, Seyed M.; Wu, Yao-Chung; Wang, Jinyang; Yang, Jun; Xia, Weiya; Sun, Yutong; Jho, Eek-hoon; Chiao, Paul J.; Hwang, Rosa F.; Ying, Haoqiang; Wang, Huamin; Zhao, Zhongming; Maitra, Anirban; Hung, Mien-Chie; Depinho, Ronald A.; Yu, Dihua Share Save Share Save Blockade of CD24 sensitizes pancreatic cancer to Kras inhibitorsWei, Yongkun; Liu, Minghui; Yen, Er-Yen; Yao, Jun; Nguyen, Phuoc T.; Wang, Xiaofei; Yang, Zecheng; Yousef, Abdelrahman; Pan, Dean; Jin, Yanqing; Theady, Madelaine S.; Park, Jangho; Cai, Yiming; Takeda, Mitsunobu; Vasquez, Matthew; Zhou, Yong; Zhao, Hong; Viale, Andrea; Wang, Huamin; Zhao, Dan; DePinho, Ronald A.; Yao, Wantong; Ying, Haoqiang Share Save Clonal dominance defines metastatic dissemination in pancreatic cancerHo, I-Lin; Li, Chieh-Yuan; Wang, Fuchenchu; Zhao, Li; Liu, Jingjing; Yen, Er-Yen; Dyke, Charles A.; Shah, Rutvi; Liu, Zhaoliang; Cetin, Ali Osman; Chu, Yanshuo; Citron, Francesca; Attanasio, Sergio; Corti, Denise; Darbaniyan, Faezeh; Del Poggetto, Edoardo; Loponte, Sara; Liu, Jintan; Soeung, Melinda; Chen, Ziheng; Jiang, Shan; Jiang, Hong; Inoue, Akira; Gao, Sisi; Deem, Angela; Feng, Ningping; Ying, Haoqiang; Kim, Michael; Giuliani, Virginia; Genovese, Giannicola; Zhang, Jianhua; Futreal, Andrew; Maitra, Anirban; Heffernan, Timothy; Wang, Linghua; Do, Kim-Anh; Gargiulo, Gaetano; Draetta, Giulio; Carugo, Alessandro; Lin, Ruitao; Viale, Andrea Share Save Share Save Share Save CDK8 and CXCL2 remodel the tumor microenvironment to contribute to KRASG12D small molecule inhibition resistance in pancreatic ductal adenocarcinomaMcAndrews, Kathleen M.; Mahadevan, Krishnan K.; Li, Bingrui; Sockwell, Amari M.; Morse, Sami J.; Kelly, Patience J.; Kirtley, Michelle L.; Conner, Meagan R.; Patel, Sarah I.; Khumbar, Shreyasee V.; Arian, Kent A.; Barekatain, Yasaman; Diaz, Barbara A. Moreno; Lyu, Hengyu; Sugimoto, Hikaru; Sthanam, Lakshmi Kavitha; Sobhani, Navid; Paradiso, Francesca; Bernard, Vincent; Guerrero, Paola; Ying, Haoqiang; Maitra, Anirban; Heffernan, Timothy P.; Kalluri, Raghu Share Save Extinction of oncogenic Kras in genetic mouse models eradicates pancreatic cancer by inducing Fas-dependent apoptosis by CD8+T cellsLeBleu, Valerie S.; Mahadevan, Krishnan K.; Ramirez, Elena V.; Chen, Yang; Li, Bingrui; Sockwell, Amari M.; Gagea, Mihai; Sugimoto, Hikaru; Tampe, Desiree; Zeisberg, Michael; Ying, Haoqiang; Jain, Abhinav K.; DePinho, Ronald A.; Maitra, Aniban; McAndrews, Kathleen M.; Kalluri, Raghu Share Save Share Save Share Save Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cellsMahadevan, Krishnan K.; Lebleu, Valerie S.; Ramirez, Elena, V; Chen, Yang; Li, Bingrui; Sockwell, Amari M.; Gagea, Mihai; Sugimoto, Hikaru; Sthanam, Lakshmi Kavitha; Tampe, Desiree; Zeisberg, Michael; Ying, Haoqiang; Jain, Abhinav K.; Depinho, Ronald A.; Maitra, Anirban; Mcandrews, Kathleen M.; Kalluri, Raghu Share Save Ether phospholipids metabolism is a latent vulnerability for pancreatic cancer resistanceChen, Ziheng; Ho, I-Lin; Soeung, Melinda; Yen, Er-Yen; Rose, Johnathon; Srinivasan, Sanjana; Deem, Angela; Gao, Sisi; Ying, Haoqiang; Draetta, Giulio Share Save Histone demethylase KDM2A is a selective vulnerability of cancers relying on alternative telomere maintenanceLi, Fei; Wang, Yizhe; Hwang, Inah; Jang, Ja-Young; Xu, Libo; Deng, Zhong; Yu, Eun Young; Cai, Yiming; Wu, Caizhi; Han, Zhenbo; Huang, Yu-Han; Huang, Xiangao; Zhang, Ling; Yao, Jun; Lue, Neal F.; Lieberman, Paul M.; Ying, Haoqiang; Paik, Jihye; Zheng, Hongwu Share Save Share Save Tumor-associated nonmyelinating Schwann cell- expressed PVT1 promotes pancreatic cancer kynurenine pathway and tumor immune exclusionSun, Chengcao; Ye, Youqiong; Tan, Zhi; Liu, Yuan; Li, Yajuan; Hu, Wei; Liang, Ke; Egranov, Sergey D.; Huang, Lisa Angela; Zhang, Zhao; Zhang, Yaohua; Yao, Jun; Nguyen, Tina K.; Zhao, Zilong; Wu, Andrew; Marks, Jeffrey R.; Caudle, Abigail S.; Sahin, Aysegul A.; Gao, Jianjun; Gammon, Seth T.; Piwnica-Worms, David; Hu, Jian; Chiao, Paul J.; Yu, Dihua; Hung, Mien-Chie; Curran, Michael A.; Calin, George A.; Ying, Haoqiang; Han, Leng; Lin, Chunru; Yang, Liuqing Share Save Targeting T cell checkpoints 41BB and LAG3 and myeloid cell CXCR1/CXCR2 results in antitumor immunity and durable response in pancreatic cancerGulhati, Pat; Schalck, Aislyn; Jiang, Shan; Shang, Xiaoying; Wu, Chang-Jiun; Hou, Pingping; Ruiz, Sharia Hernandez; Soto, Luisa Solis; Parra, Edwin; Ying, Haoqiang; Han, Jincheng; Dey, Prasenjit; Li, Jun; Deng, Pingna; Sei, Emi; Maeda, Dean Y.; Zebala, John A.; Spring, Denise J.; Kim, Michael; Wang, Huamin; Maitra, Anirban; Moore, Dirk; Clise-Dwyer, Karen; Wang, Y. Alan; Navin, Nicholas E.; DePinho, Ronald A. Share Save Cancer-associated fibroblasts employ NUFIP1-dependent autophagy to secrete nucleosides and support pancreatic tumor growthYuan, Meng; Tu, Bo; Li, Hengchao; Pang, Huanhuan; Zhang, Nan; Fan, Minghe; Bai, Jingru; Wang, Wei; Shu, Zhaoqi; DuFort, Christopher C.; Huo, Sihan; Zhai, Jie; Yao, Ke; Wang, Lina; Ying, Haoqiang; Zhu, Wei-Guo; Fu, Deliang; Hu, Zeping; Zhao, Ying Share Save 
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