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Multiomic Immune Profiling of Pediatric Transplant Recipients Identifies Cell States Associated with Vaccine Response Wedel, Johannes; Tang, Ying; Alsairafi, Bayan; Do, Vicki; Maslyar, Madeline; Fleming, Ryan; Schwartz, Marc A.; Gerdemann, Ulrike; Albanese, Alexandre; Mitsialis, Vanessa; Collen, Lauren V.; Nishitani, Miki; Bresnahan, Mairead; Saccocia, Gwen; Bearup, Richelle; Okoroafor, Ibeawuchi; Siegel, Steven J.; Wachter, Franziska; Waters, Katherine; Weichert-Leahey, Nina; Clarke, Nigel J.; Mandl, Kenneth D.; Kean, Leslie S.; Snapper, Scott B.; Briscoe, David M.; Horwitz, Bruce H. Share Save
A Collection of Patient-Derived Intestinal Organoid Lines Reveals Epithelial Phenotypes Associated with Genetic Drivers of Pediatric Inflammatory Bowel Disease Jeshvaghani, Zahra Shojaei; Argmann, Carmen; de Vries, Maaike H.; van Es, Johan H.; Collen, Lauren, V; Kotlarz, Daniel; Sveen, Mia; Comella, Phillip H.; Snapper, Scott B.; Klein, Christoph; Schadt, Eric E.; Clevers, Hans; Mokry, Michal; Kuijk, Ewart; Nieuwenhuis, Edward Share Save
Expert recommendations to standardize transcriptomic analysis in inflammatory bowel disease clinical trials Linggi, Bryan; Azucena, Salas; Steere, Boyd; Verstockt, Bram; Alsoud, Dahham; Casero, David; Mcgovern, Dermot; Chan, Eileen; Smith, Michelle, I; Ungaro, Federica; Rieder, Florian; Aden, Konrad; Shackelton, Lisa M.; Massimino, Luca; Neurath, Markus; Allez, Matthieu; Atreya, Raja; Snapper, Scott B.; Raine, Tim; Ahuja, Vineet; Haberman, Yael; Feagan, Brian G.; Vande Casteele, Niels Share Save
INTERLEUKIN-1 AS A DRIVER OF ENDOTHELIAL CELL ACTIVATION AND VENULAR IDENTITY AT THE IBD ULCER NICHE Mitsialis, Vanessa; Marco, Losa; Barends, Jared; Anziano, Emma; Anderson, Michael; Plone, Abigail; Field, Michael; Sveen, Mia; Bearup, Richelle; Eran, Alal; Thiagarajah, Jay; Horwitz, Bruce; Snapper, Scott Share Save
DOP072 The IL1-dependent transcription factor MEOX1 as a driver of differentiation programs in ACKR1+endothelial cells of inflammatory bowel disease granulation tissue Mitsialis, V; Losa, M.; Lance, C.; Tang, Y.; Barends, J.; Anziano, E.; Field, M.; Eran, A.; Horwitz, B.; Muise, A.; Klein, C.; Kotlarz, D.; Argmann, C.; Schadt, E.; Snapper, S. Share Save
Comprehensive evaluation and practical guideline of gating methods for high-dimensional cytometry data: manual gating, unsupervised clustering, and auto-gating Liu, Peng; Pan, Yuchen; Chang, Hung-Ching; Wang, Wenjia; Fang, Yusi; Xue, Xiangning; Zou, Jian; Toothaker, Jessica M.; Olaloye, Oluwabunmi; Santiago, Eduardo Gonzalez; Mccourt, Black; Mitsialis, Vanessa; Presicce, Pietro; Kallapur, Suhas G.; Snapper, Scott B.; Liu, Jia-Jun; Tseng, George C.; Konnikova, Liza; Liu, Silvia Share Save
Human ITGAV variants are associated with immune dysregulation, brain abnormalities, and colitis Ghasempour, Sina; Warner, Neil; Guan, Rei; Rodari, Marco M.; Ivanochko, Danton; Whittaker Hawkins, Ryder; Marwaha, Ashish; Nowak, Jan K.; Liang, Yijing; Mulder, Daniel J.; Stallard, Lorraine; Li, Michael; Yu, Daniel D.; Pluthero, Fred G.; Batura, Vritika; Zhao, Mo; Siddiqui, Iram; Upton, Julia E. M.; Hulst, Jessie M.; Kahr, Walter H. A.; Mendoza-Londono, Roberto; Charbit-Henrion, Fabienne; Hoefsloot, Lies H.; Khiat, Anis; Moreira, Diana; Trindade, Eunice; Espinheira, Maria do Ceu; Pinto Pais, Isabel; Weerts, Marjolein J. A.; Douben, Hannie; Kotlarz, Daniel; Snapper, Scott B.; Klein, Christoph; Dowling, James J.; Julien, Jean-Philippe; Joosten, Marieke; Cerf-Bensussan, Nadine; Freeman, Spencer A.; Parlato, Marianna; van Ham, Tjakko J.; Muise, Aleixo M. Share Save
Spatiotemporal coordination of actin regulators generates invasive protrusions in cell-cell fusion Lu, Yue; Walji, Tezin; Ravaux, Benjamin; Pandey, Pratima; Yang, Changsong; Li, Bing; Luvsanjav, Delgermaa; Lam, Kevin H.; Zhang, Ruihui; Luo, Zhou; Zhou, Chuanli; Habela, Christa W.; Snapper, Scott B.; Li, Rong; Goldhamer, David J.; Schmidtke, David W.; Pan, Duojia; Svitkina, Tatyana M.; Chen, Elizabeth H. Share Save
Progression of Pediatric Crohn's Disease Is Associated With Anti-Tumor Necrosis Factor Timing and Body Mass Index Z-Score Normalization Geem, Duke; Hercules, David; Pelia, Ranjit S.; Venkateswaran, Suresh; Griffiths, Anne; Noe, Joshua D.; Dotson, Jennifer L.; Snapper, Scott; Rabizadeh, Shervin; Rosh, Joel R.; Baldassano, Robert N.; Markowitz, James F.; Walters, Thomas D.; Ananthakrishnan, Ashwin; Sharma, Garima; Denson, Lee A.; Hyams, Jeffrey S.; Kugathasan, Subra Share Save
Bacterial Sphingolipids Exacerbate Colitis by Inhibiting ILC3-derived IL-22 Production Bao, Bin; Wang, Youyuan; Boudreau, Pavl; Song, Xinyang; Wu, Meng; Chen, Xi; Patik, Izabel; Tang, Ying; Ouahed, Jodie; Ringel, Amit; Barends, Jared; Wu, Chuan; Balskus, Emily; Thiagarajah, Jay; Liu, Jian; Wessels, Michael R.; Lencer, Wayne Isaac; Kasper, Dennis L.; An, Dingding; Horwitz, Bruce Harold; Snapper, Scott B. Share Save
Intestinal microbiome and metabolome signatures in patients with chronic granulomatous disease Chandrasekaran, Prabha; Han, Yu; Zerbe, Christa S.; Heller, Theo; DeRavin, Suk See; Kreuzberg, Samantha A.; Marciano, Beatriz E.; Siu, Yik; Jones, Drew R.; Abraham, Roshini S.; Stephens, Michael C.; Tsou, Amy M.; Snapper, Scott; Conlan, Sean; Subramanian, Poorani; Quinones, Mariam; Grou, Caroline; Calderon, Virginie; Deming, Clayton; Leiding, Jennifer W.; Arnold, Danielle E.; Logan, Brent R.; Griffith, Linda M.; Petrovic, Aleksandra; Mousallem, Talal I.; Kapoor, Neena; Heimall, Jennifer R.; Barnum, Jessie L.; Kapadia, Malika; Wright, Nicola; Rayes, Ahmad; Chandra, Sharat; Broglie, Larisa A.; Chellapandian, Deepak; Deal, Christin L.; Grunebaum, Eyal; Lim, Stephanie Si; Mallhi, Kanwaldeep; Marsh, Rebecca A.; Murguia-Favela, Luis; Parikh, Suhag; Touzot, Fabien; Cowan, Morton J.; Dvorak, Christopher C.; Haddad, Elie; Kohn, Donald B.; Notarangelo, Luigi D.; Pai, Sung-Yun; Puck, Jennifer M.; Pulsipher, Michael A.; Torgerson, Troy R.; Kang, Elizabeth M.; Malech, Harry L.; Segre, Julia A.; Bryant, Clare E.; Holland, Steven M.; Falcone, Emilia Liana Share Save
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The IL-10 receptor inhibits cell extrinsic signals necessary for STAT1-dependent macrophage accumulation during colitis Patik, Izabel; Redhu, Naresh S.; Eran, Alal; Bao, Bin; Nandy, Anubhab; Tang, Ying; El Sayed, Shorouk; Shen, Zeli; Glickman, Jonathan; Fox, James G.; Snapper, Scott B.; Horwitz, Bruce H. Share Save
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Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients Wu, Yiming; Gettler, Kyle; Kars, Meltem Ece; Giri, Mamta; Li, Dalin; Bayrak, Cigdem Sevim; Zhang, Peng; Jain, Aayushee; Maffucci, Patrick; Sabic, Ksenija; Van Vleck, Tielman; Nadkarni, Girish; Denson, Lee A.; Ostrer, Harry; Levine, Adam P.; Schiff, Elena R.; Segal, Anthony W.; Kugathasan, Subra; Stenson, Peter D.; Cooper, David N.; Schumm, L. Philip; Snapper, Scott; Daly, Mark J.; Haritunians, Talin; Duerr, Richard H.; Silverberg, Mark S.; Rioux, John D.; Brant, Steven R.; McGovern, Dermot P. B.; Cho, Judy H.; Itan, Yuval Share Save
Targeted deletion of integrin-linked kinase reveals a role in T-cell chemotaxis and survival Liu, E; Sinha, S; Williams, C; Cyrille, M; Heller, E; Snapper, SB; Georgopoulos, K; St-Arnaud, R; Force, T; Dedhar, S; Gerszten, RE Share Save
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