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Gonzalo López

Icahn School of Medicine at Mount Sinai
H-index:29
Citation Count:4,282
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Quantifying rate-limiting genetic variation in breast and ovarian tumourigenesis

量化乳腺癌和卵巢癌发生过程中的限速遗传变异

eBioMedicine
IF10.8
2026-02-210
OAAI
Kathleen E. Houlahan; Mahad Bihie; Yves Greatti; Julián Grandvallet Contreras; Daniel J. Fulop; Gonzalo Lopez; Marc Williams; Hsin-Hsiung Huang; Peter Van Loo; Paul C. Boutros; Kuan-lin Huang
Germline pathogenic variants in neuroblastoma patients are enriched in BARD1 and predict worse survival
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
IF7.2
2023-09-0912
OA
Kim, Jung; Vaksman, Zalman; Egolf, Laura E.; Kaufman, Rebecca; Evans, J. Perry; Conkrite, Karina L.; Danesh, Arnavaz; Lopez, Gonzalo; Randall, Michael P.; Dent, Maiah H.; Farra, Lance M.; Menghani, Neil L.; Dymek, Malwina; Desai, Heena; Hausler, Ryan; Hicks, Belynda; Auvil, Jaime Guidry; Gerhard, Daniela S.; Hakonarson, Hakon; Maxwell, Kara N.; Cole, Kristina A.; Pugh, Trevor J.; Bosse, Kristopher R.; Khan, Javed; Wei, Jun S.; Maris, John M.; Stewart, Douglas R.; Diskin, Sharon J.
Integrative Genomic Analyses Identify LncRNA Regulatory Networks across Pediatric Leukemias and Solid Tumors

整合基因组分析确定跨小儿白血病和实体瘤的LncRNA调控网络

CANCER RESEARCH
IF16.6
2023-08-163
PRE
Modi, Apexa; Lopez, Gonzalo; Conkrite, Karina L.; Su, Chun; Leung, Tsz Ching; Ramanan, Sathvik; Manduchi, Elisabetta; Johnson, Matthew E.; Cheung, Daphne; Gadd, Samantha; Zhang, Jinghui; Smith, Malcolm A.; Guidry Auvil, Jaime M.; Meshinchi, Soheil; Perlman, Elizabeth J.; Hunger, Stephen P.; Maris, John M.; Wells, Andrew D.; Grant, Struan F. A.; Diskin, Sharon J.
Alternative lengthening of telomeres (ALT) in pediatric high-grade gliomas can occur without ATRX mutation and is enriched in patients with pathogenic germline mismatch repair (MMR) variants

在没有ATRX突变的情况下，小儿高级别神经胶质瘤中端粒 (ALT) 的替代延长可能会发生，并且在致病性种系错配修复 (MMR) 变体的患者中富集。

NEURO-ONCOLOGY
IF13.4
2022-12-2010
OAAI
Stundon, Jennifer L.; Ijaz, Heba; Gaonkar, Krutika S.; Kaufman, Rebecca S.; Jin, Run; Karras, Anastasios; Vaksman, Zalman; Kim, Jung; Corbett, Ryan J.; Lueder, Matthew R.; Miller, Daniel P.; Guo, Yiran; Santi, Mariarita; Li, Marilyn; Lopez, Gonzalo; Storm, Phillip B.; Resnick, Adam C.; Waanders, Angela J.; MacFarland, Suzanne P.; Stewart, Douglas R.; Diskin, Sharon J.; Rokita, Jo Lynne; Cole, Kristina A.
GAS7 Deficiency Promotes Metastasis in MYCN-Driven Neuroblastoma
CANCER RESEARCH
IF16.6
2021-02-1816
OA
Dong, Zhiwei; Yeo, Kok Siong; Lopez, Gonzalo; Zhang, Cheng; Eggum, Erin N. Dankert; Rokita, Jo Lynne; Ung, Choong Yong; Levee, Taylor M.; Her, Zuag Paj; Howe, Cassie J.; Hou, Xiaonan; van Ree, Janine H.; Li, Shuai; He, Shuning; Tao, Ting; Fritchie, Karen; Torres-Mora, Jorge; Lehman, Julia S.; Meves, Alexander; Razidlo, Gina L.; Rathi, Komal S.; Weroha, S. John; Look, A. Thomas; van Deursen, Jan M.; Li, Hu; Westendorf, Jennifer J.; Maris, John M.; Zhu, Shizhen
CAR-T cell-mediated depletion of immunosuppressive tumor-associated macrophages promotes endogenous antitumor immunity and augments adoptive immunotherapy
NATURE COMMUNICATIONS
IF15.7
2021-02-09201
OAAI
Rodriguez-Garcia, Alba; Lynn, Rachel C.; Poussin, Mathilde; Eiva, Monika A.; Shaw, Lauren C.; O'Connor, Roddy S.; Minutolo, Nicholas G.; Casado-Medrano, Victoria; Lopez, Gonzalo; Matsuyama, Takami; Powell, Daniel J., Jr.
Somatic structural variation targets neurodevelopmental genes and identifies SHANK2 as a tumor suppressor in neuroblastoma
GENOME RESEARCH
IF5.5
2020-08-1319
OAAI
Lopez, Gonzalo; Conkrite, Karina L.; Doepner, Miriam; Rathi, Komal S.; Modi, Apexa; Vaksman, Zalman; Farra, Lance M.; Hyson, Eric; Noureddine, Moataz; Wei, Jun S.; Smith, Malcolm A.; Asgharzadeh, Shahab; Seeger, Robert C.; Khan, Javed; Auvil, Jaime Guidry; Gerhard, Daniela S.; Maris, John M.; Diskin, Sharon J.
Telomere Maintenance Mechanisms Define Clinical Outcome in High-Risk Neuroblastoma
CANCER RESEARCH
IF16.6
2020-06-1559
OAAI
Koneru, Balakrishna; Lopez, Gonzalo; Farooqi, Ahsan; Conkrite, Karina L.; Nguyen, Thinh H.; Macha, Shawn J.; Modi, Apexa; Rokita, Jo Lynne; Urias, Eduardo; Hindle, Ashly; Davidson, Heather; Mccoy, Kristyn; Nance, Jonas; Yazdani, Vanda; Irwin, Meredith S.; Yang, Shengping; Wheeler, David A.; Maris, John M.; Diskin, Sharon J.; Reynolds, C. Patrick
Role of Tau Protein in Remodeling of Circadian Neuronal Circuits and Sleep
FRONTIERS IN AGING NEUROSCIENCE
IF4.5
2019-11-2123
OAAI
Ames, Mercedes; Alaniz, Maria E.; Karam, Celine S.; Cho, Joshua D.; Lopez, Gonzalo; Javitch, Jonathan A.; Santa-Maria, Ismael
Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design
CELL REPORTS
IF6.9
2019-11-01114
OAAI
Rokita, Jo Lynne; Rathi, Komal S.; Cardenas, Maria F.; Upton, Kristen A.; Jayaseelan, Joy; Cross, Katherine L.; Pfeil, Jacob; Egolf, Laura E.; Way, Gregory P.; Farrel, Alvin; Kendsersky, Nathan M.; Patel, Khushbu; Gaonkar, Krutika S.; Modi, Apexa; Berko, Esther R.; Lopez, Gonzalo; Vaksman, Zalman; Mayoh, Chelsea; Nance, Jonas; McCoy, Kristyn; Haber, Michelle; Evans, Kathryn; McCalmont, Hannah; Bendak, Katerina; Boehm, Julia W.; Marshall, Glenn M.; Tyrrell, Vanessa; Kalletla, Karthik; Braun, Frank K.; Qi, Lin; Du, Yunchen; Zhang, Huiyuan; Lindsay, Holly B.; Zhao, Sibo; Shu, Jack; Baxter, Patricia; Morton, Christopher; Kurmashev, Dias; Zheng, Siyuan; Chen, Yidong; Bowen, Jay; Bryan, Anthony C.; Leraas, Kristen M.; Coppens, Sara E.; Doddapaneni, HarshaVardhan; Momin, Zeineen; Zhang, Wendong; Sacks, Gregory, I; Hart, Lori S.; Krytska, Kateryna; Mosse, Yael P.; Gatto, Gregory J.; Sanchez, Yolanda; Greene, Casey S.; Diskin, Sharon J.; Vaske, Olena Morozova; Haussler, David; Gastier-Foster, Julie M.; Kolb, E. Anders; Gorlick, Richard; Li, Xiao-Nan; Reynolds, C. Patrick; Kurmasheva, Raushan T.; Houghton, Peter J.; Smith, Malcolm A.; Lock, Richard B.; Raman, Pichai; Wheeler, David A.; Maris, John M.
Pediatric high-grade glioma resources from the Children's Brain Tumor Tissue Consortium

来自儿童脑肿瘤组织联盟的小儿高级神经胶质瘤资源

NEURO-ONCOLOGY
IF13.4
2019-10-1521
OAAI
Ijaz, Heba; Koptyra, Mateusz; Gaonkar, Krutika S.; Rokita, Jo Lynne; Baubet, Valerie P.; Tauhid, Lamiya; Zhu, Yuankun; Brown, Miguel; Lopez, Gonzalo; Zhang, Bo; Diskin, Sharon J.; Vaksman, Zalman; Mason, Jennifer L.; Appert, Elizabeth; Lilly, Jena; Lulla, Rishi; De Raedt, Thomas; Heath, Allison P.; Felmeister, Alex; Raman, Pichai; Nazarian, Javad; Santi, Maria Rita; Storm, Phillip B.; Resnick, Adam; Waanders, Angela J.; Cole, Kristina A.
Germline 16p11.2 Microdeletion Predisposes to Neuroblastoma
AMERICAN JOURNAL OF HUMAN GENETICS
IF8.1
2019-09-0133
OAAI
Egolf, Laura E.; Vaksman, Zalman; Lopez, Gonzalo; Rokita, Jo Lynne; Modi, Apexa; Basta, Patricia, V; Hakonarson, Hakon; Olshan, Andrew F.; Diskin, Sharon J.
Subtype-selective lethal molecules disrupt the regulatory module that drives high-risk neuroblastoma
CANCER RESEARCH
IF16.6
2018-07-010
PRE
Stokes, Michael E.; Vasciaveo, Alessandro; Small, Jonnell Candice; Rajbhandari, Presha; Lopez, Gonzalo; Califano, Andrea; Stockwell, Brent R.
Transcription factor activating protein 4 is synthetically lethal and a master regulator of MYCN-amplified neuroblastoma
ONCOGENE
IF7.3
2018-06-0727
OAAI
Boboila, Shuobo; Lopez, Gonzalo; Yu, Jiyang; Banerjee, Debarshi; Kadenhe-Chiweshe, Angela; Connolly, Eileen P.; Kandel, Jessica J.; Rajbhandari, Presha; Silva, Jose M.; Califano, Andrea; Yamashiro, Darrell J.
Cross-Cohort Analysis Identifies a TEAD4-MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma

跨队列分析确定TEAD4-MYCN正反馈回路为高危神经母细胞瘤的核心调控元件

CANCER DISCOVERY
IF33.3
2018-04-30111
OAAI
Rajbhandari, Presha; Lopez, Gonzalo; Capdevila, Claudia; Salvatori, Beatrice; Yu, Jiyang; Rodriguez-Barrueco, Ruth; Martinez, Daniel; Yarmarkovich, Mark; Weichert-Leahey, Nina; Abraham, Brian J.; Alvarez, Mariano J.; Iyer, Archana; Harenza, Jo Lynne; Oldridge, Derek; De Preter, Katleen; Koster, Jan; Asgharzadeh, Shahab; Seeger, Robert C.; Wei, Jun S.; Khan, Javed; Vandesompele, Jo; Mestdagh, Pieter; Versteeg, Rogier; Look, A. Thomas; Young, Richard A.; Iavarone, Antonio; Lasorella, Anna; Silva, Jose M.; Maris, John M.; Califano, Andrea
Dissecting telomere maintenance mechanisms in neuroblastoma
CANCER RESEARCH
IF16.6
2017-07-011
PRE
Lopez, Gonzalo; Conkrite, Karina; Hong, Kendra; Harenza, Jo Lynne; Maris, John M.; Diskin, Sharon
11q deletion in neuroblastoma: a review of biological and clinical implications
MOLECULAR CANCER
IF33.9
2017-06-29102
OAAI
Mlakar, Vid; Mlakar, Simona Jurkovic; Lopez, Gonzalo; Maris, John M.; Ansari, Marc; Gumy-Pause, Fabienne
HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma
NATURE MEDICINE
IF50
2016-09-12176
OAAI
Tavana, Omid; Li, Dawei; Dai, Chao; Lopez, Gonzalo; Banerjee, Debarshi; Kon, Ning; Chen, Chao; Califano, Andrea; Yamashiro, Darrell J.; Sun, Hongbin; Gu, Wei
Selective cross-cohort discovery of transcriptional mechanisms presiding over high-risk neuroblastoma subtype state maintenance
CANCER RESEARCH
IF16.6
2016-07-150
PRE
Rajbhandari, Presha; Lopez, Gonzalo; Yu, Jiyang; Rodriguez-Barrueco, Ruth; Alvarez, Mariano; Martinez, Daniel; Yarmarkovich, Mark; Vandesompele, Jo; Mestdagh, Pieter; Silva, Jose M.; Lasorella, Anna; Lavarone, Antonio; Mans, John M.; Califano, Andrea
Oncogenic dysregulations in neuroblastoma are associated with distal large chromosomal aberrations
CANCER RESEARCH
IF16.6
2015-11-150
PRE
Lopez, Gonzalo; Alvarez, Mariano; Chen, James; Rajbhandari, Presha; Cole, Kristina A.; Attiyeh, Edward F.; Diskin, Sharon; Mestdagh, Pieter; Vandesompele, Jo; Maris, John M.; Califano, Andrea

Research Directions

The data has not been retrieved yet.
M
Michael L. Tress
H-index:47Papers:111Citations:2.8万
A
Alfonso Valencia
H-index:127Papers:866Citations:8.1万
J
John M. Maris
H-index:115Papers:1,351Citations:5.3万
S
Sharon J. Diskin
H-index:46Papers:335Citations:1.0万
A
Andrea Califano
H-index:96Papers:1,072Citations:5.4万
J
Jo Lynne Rokita
H-index:20Papers:235Citations:1,702
Z
Zalman Vaksman
H-index:20Papers:78Citations:1,381
K
Karina L. Conkrite
H-index:14Papers:134Citations:1,126
A
Apexa Modi
H-index:11Papers:104Citations:522
P
Presha Rajbhandari
H-index:15Papers:63Citations:2,975