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Proteomics and personalized PDX models identify treatment for a progressive malignancy within an actionable timeframe Barnabas, Georgina D.; Bhat, Tariq A.; Goebeler, Verena; Leclair, Pascal; Azzam, Nadine; Melong, Nicole; Anderson, Colleen; Gom, Alexis; An, Seohee; Ergin, Enes K.; Shen, Yaoqing; Conrrero, Agustina; Mungall, Andrew J.; Mungall, Karen L.; Maxwell, Christopher A.; Reid, Gregor S. D.; Hirst, Martin; Jones, Steven; Chan, Jennifer A.; Senger, Donna L.; Berman, Jason N.; Parker, Seth J.; Bush, Jonathan W.; Strahlendorf, Caron; Deyell, Rebecca J.; Lim, C. James; Lange, Philipp F. Share Save
Restricting lysine normalizes toxic catabolites associated with ALDH7A1 deficiency in cells and mice Johal, Amritpal S.; Al-Shekaili, Hilal H.; Abedrabbo, Muna; Kehinde, Abisola Z.; Towriss, Morgan; Koe, Jessica C.; Hewton, Keeley G.; Thomson, Sarah B.; Ciernia, Annie, V; Leavitt, Blair; Parker, Seth J. Share Save
Pancreatic cancer tumor organoids exhibit subtype-specific differences in metabolic profiles Ali, Hassan A.; Karasinska, Joanna M.; Topham, James T.; Johal, Danisha; Kalloger, Steve; Metcalfe, Andrew; Warren, Cassia S.; Miyagi, Anthony; Tao, Lan V.; Kevorkova, Maya; Chafe, Shawn C.; Mcdonald, Paul C.; Dedhar, Shoukat; Parker, Seth J.; Renouf, Daniel J.; Schaeffer, David F. Share Save
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Prioritizing treatment targets for an adolescent with metastatic processive malignancy using proteomics and personalized xenograft models within an actionable timeframe Barnabas, Georgina D.; Bhat, Tariq A.; Goebeler, Verena; Leclair, Pascal; Azzam, Nadine; Melong, Nicole; Berman, Jason N.; Chan, Jennifer A.; Senger, Donna L.; Parker, Seth; Maxwell, Christopher A.; Reid, Gregor S.; Bush, Jonathan; Strahlendorf, Caron; Deyell, Rebecca; Lim, C. James; Lange, Philipp F. Share Save
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Targeting pancreatic cancer metabolic dependencies through glutamine antagonism Encarnacion-Rosado, Joel; Sohn, Albert S. W.; Biancur, Douglas E.; Lin, Elaine Y.; Osorio-Vasquez, Victoria; Rodrick, Tori; Gonzalez-Baerga, Diana; Zhao, Ende; Yokoyama, Yumi; Simeone, Diane M.; Jones, Drew R.; Parker, Seth J.; Wild, Robert; Kimmelman, Alec C. Share Save
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Acetate reprograms gut microbiota during alcohol consumption Martino, Cameron; Zaramela, Livia S.; Gao, Bei; Embree, Mallory; Tarasova, Janna; Parker, Seth J.; Wang, Yanhan; Chu, Huikuan; Chen, Peng; Lee, Kuei-Chuan; Galzerani, Daniela Domingos; Gengatharan, Jivani M.; Lekbua, Asama; Neal, Maxwell; Knight, Rob; Tsukamoto, Hidekazu; Metallo, Christian M.; Schnabl, Bernd; Zengler, Karsten Share Save
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Spontaneous hydrolysis and spurious metabolic properties of α-ketoglutarate esters Parker, Seth J.; Encarnacion-Rosado, Joel; Hollinshead, Kate E. R.; Hollinshead, David M.; Ash, Leonard J.; Rossi, Juan A. K.; Lin, Elaine Y.; Sohn, Albert S. W.; Philips, Mark R.; Jones, Drew R.; Kimmelman, Alec C. Share Save
Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma Zhang, Hai-Feng; Hughes, Christopher S.; Li, Wei; He, Jian-Zhong; Surdez, Didier; El-Naggar, Amal M.; Cheng, Hongwei; Prudova, Anna; Delaidelli, Alberto; Negri, Gian Luca; Li, Xiaojun; Orum-Madsen, Maj Sofie; Lizardo, Michael M.; Oo, Htoo Zarni; Colborne, Shane; Shyp, Taras; Scopim-Ribeiro, Renata; Hammond, Colin A.; Dhez, Anne-Chloe; Langman, Sofya; Lim, Jonathan K. M.; Kung, Sonia H. Y.; Li, Amy; Steino, Anne; Daugaard, Mads; Parker, Seth J.; Geltink, Ramon I. Klein; Orentas, Rimas J.; Xu, Li-Yan; Morin, Gregg B.; Delattre, Olivier; Dimitrov, Dimiter S.; Sorensen, Poul H. Share Save
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Disruption of redox homeostasis for combinatorial drug efficacy inK-Rastumors as revealed by metabolic connectivity profiling Gaglio, Daniela; Bonanomi, Marcella; Valtorta, Silvia; Bharat, Rohit; Ripamonti, Marilena; Conte, Federica; Fiscon, Giulia; Righi, Nicole; Napodano, Elisabetta; Papa, Federico; Raccagni, Isabella; Parker, Seth J.; Cifola, Ingrid; Camboni, Tania; Paci, Paola; Colangelo, Anna Maria; Vanoni, Marco; Metallo, Christian M.; Moresco, Rosa Maria; Alberghina, Lilia Share Save
Selective Alanine Transporter Utilization Creates a Targetable Metabolic niche in Pancreatic Cancer Parker, Seth J.; Amendola, Caroline R.; Hollinshead, Kate E. R.; Yu, Qijia; Yamamoto, Keisuke; Encarnacion-Rosado, Joel; Rose, Rebecca E.; LaRue, Madeleine M.; Sohn, Albert S. W.; Biancur, Doug E.; Paulo, Joao A.; Gygi, Steven P.; Jones, Drew R.; Wang, Huamin; Philips, Mark R.; Bar-Sagi, Dafna; Mancias, Joseph D.; Kimmelman, Alec C. Share Save
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