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J

John F. Engelhardt

University of Alabama at Birmingham

95H-index
432Paper Count
3.1WCitation Count
Published Papers 201
Publication Date
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CFTR facilitates fluid secretion by ferret alveolar type 2 cells
errJournal of Cystic Fibrosis
IF6
err2026-05-15
err0
PREAI
errLiyuan Yang; Changfu Yao; Javahir Hajibabazade; Yabo Ma; Katherine Drake; Oluwadarasimi Atanda; Zheqing Hu; Barry R. Stripp; Xiaoming Liu; John F Engelhardt
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Research updates in cystic fibrosis related diabetes: Understanding pathophysiology, expanding animal and human islet models, and advancing clinical and translational research
errJournal of Cystic Fibrosis
IF6
err2026-04-05
err0
PREAI
errMelissa S. Putman; Rebecca L. Hull-Meichle; Shafagh A. Waters; Katherine Tuggle; Paula Sommer; Rebecca Conway; Lee A. Borthwick; Jakob G. Knudsen; E.Danielle Dean; Sarah A. Stanley; Xingshen Sun; John F. Engelhardt; Shih-Hsing Leir; Lena Eliasson; Bibi Uhre Nielsen; Darko Stefanovski; Amanda Brennan; Charlotte K. Boughton; Andrea Kelly; Amir Moheet
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errSave
Amino acid-derived ionizable lipids enable inhaled base editing for therapeutic gene correction in the lung
errNature Materials
IF38.5
err2026-04-01
err0
PREAI
errFanglin Gong; Yue Xu; Jingan Chen; Shun Zhang; Songtao Dong; Lauren Healy; Breanna Seto; Muye Zhou; Rick Xing Ze Lu; Gen Li; Tyler Thomson; Yinghua Tang; Ziyan Chen; Krista Antonio; Andrew Varley; David X. W. Chen; Craig A. Hodges; Amy P. Wong; Jim Hu; Basil P. Hubbard; John F. Engelhardt; Ziying Yan; Bowen Li
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errSave
LUNAR® LNP delivery of CFTR mRNA restores channel function and improves mucociliary clearance in human and ferret cystic fibrosis airways
errMolecular Therapy
IF12
err2025-12-24
err0
PREAI
errXiaoming Liu; Javier Campos-Gomez; Meihui Luo; Jia Ma; Han-Chung Chen; Sourabh Shukla; Shuang Wu; Guy Snow; Yihua Pei; Stefen A. Boehme; David E. Geller; Steve M. Rowe; John F. Engelhardt
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errSave
Ferret model of bleomycin-induced lung injury shares features of human idiopathic pulmonary fibrosis
errnpj Regenerative Medicine
IF6.5
err2025-11-21
err0
errOAAI
errShuang Wu; Ian Driver; Meihui Luo; Hikaru Miyazaki; Smitha Shambhu; Dimitry Popov; Liyuan Yang; Jing Wang; Jia Ma; Junfeng Guo; Jarron Atha; Aleksandra Tata; Eric A. Hoffman; Yujiong Wang; Purushothama Rao Tata; Martin B. Jensen; John F. Engelhardt; Vishwaraj Sontake; Xiaoming Liu
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errSave
PRenatal mOdulator treatment to PrEvent CF complicaTions (PROTECT) workshop report
errJournal of Cystic Fibrosis
IF6
err2025-08-05
err0
errOAAI
errSylvia Szentpetery; Dara Riva; Yair J. Blumenfeld; John F. Engelhardt; Carmen Luna-Paredes; Carlos Milla; Elena K. Schneider-Futschik; Jeanne S Sheffield; Rebecca Darrah; Jane C. Davies; Patrick A Flume; Kimberly E Foil; Christopher N. Fortner; Jennifer S. Guimbellot; Anne D. Lyerly; Nicole Mayer-Hamblett; Clement L. Ren; Jacquelyn Spano; Emma M. Tillman; Aaron Trimble; Benjamin S. Wilfond; Jennifer L. Taylor-Cousar
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errSave
Recombinant Adeno-Associated Virus Vector Mediated Gene Editing in Proliferating and Polarized Cultures of Human Airway Epithelial Cells
errgene therapy
IF4
err2025-08-04
err0
PREAI
errSoo Yeun Park; Zehua Feng; Soon H. Choi; Xiujuan Zhang; Yinghua Tang; Grace N. Gasser; Donovan Richart; Feng Yuan; Jianming Qiu; John F. Engelhardt; Ziying Yan
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errSave
Novel Cystic Fibrosis Ferret Model Enables Visualization of CFTR Expression Cells and Genetic CFTR Reactivation
errgene therapy
IF4
err2025-01-10
err0
PREAI
errFeng Yuan; Xingshen Sun; Soo Yeun Park; Yinghua Tang; Zehua Feng; Mehrnoosh Ebadi; Yaling Yi; Adriane E. Thompson; Joseph D. Karippaparambil; John F. Engelhardt; Ziying Yan
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errSave
Artificial intelligence-guided design of lipid nanoparticles for pulmonary gene therapy
errNATURE BIOTECHNOLOGY
IF41.7
err2024-12-10
err0
PREAI
errWitten, Jacob; Raji, Idris; Manan, Rajith S.; Beyer, Emily; Bartlett, Sandra; Tang, Yinghua; Ebadi, Mehrnoosh; Lei, Junying; Nguyen, Dien; Oladimeji, Favour; Jiang, Allen Yujie; Macdonald, Elise; Hu, Yizong; Mughal, Haseeb; Self, Ava; Collins, Evan; Yan, Ziying; Engelhardt, John F.; Langer, Robert; Anderson, Daniel G.
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errSave
In utero and postnatal ivacaftor/ lumacaftor therapy rescues multiorgan disease in CFTR-F508del ferrets
errJCI INSIGHT
IF6.1
err2024-04-22
err2
errOAAI
errEvans, Idil Apak; Sun, Xingshen; Liang, Bo; Vegter, Amber R.; Guo, Lydia; Lynch, Thomas J.; Zhang, Yan; Zhang, Yulong; Yi, Yaling; Yang, Yu; Feng, Zehua; Park, Soo Yeun; Shonka, Amanita; McCumber, Hannah; Qi, Lisi; Wu, Peipei; Liu, Guangming; Lacina, Allison; Wang, Kai; Gibson-Corley, Katherine N.; Meyerholz, David K.; Limoli, Dominique H.; Rosen, Bradley H.; Yan, Ziying; Bartels, Douglas J.; Engelhardt, John F.
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errSave
Inflammatory Activity of Epithelial Stem Cell Variants from Cystic Fibrosis Lungs Is Not Resolved by CFTR Modulators
errAMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
IF19.4
err2023-11-01
err7
errOAAI
errWang, Shan; Niroula, Suchan; Hoffman, Ashley; Khorrami, Melika; Khorrami, Melina; Yuan, Feng; Gasser, Grace N.; Choi, Soon; Liu, Bovey; Li, Justin; Metersky, Mark L.; Vincent, Matthew; Crum, Christopher P.; Boucher, Richard C.; Karmouty-Quintana, Harry; Huang, Howard J.; Sheshadri, Ajay; Dickey, Burton F.; Parekh, Kalpaj R.; Engelhardt, John F.; McKeon, Frank D.; Xian, Wa
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errSave
Understanding and addressing the needs of people with cystic fibrosis in the era of CFTR modulator therapy
errLANCET RESPIRATORY MEDICINE
IF32.8
err2023-10-01
err24
PREAI
errHisert, Katherine B.; Birket, Susan E.; Clancy, John Paul; Downey, Damian G.; Engelhardt, John F.; Fajac, Isabelle; Gray, Robert D.; Lachowicz-Scroggins, Marrah E.; Mayer-Hamblett, Nicole; Thibodeau, Patrick; Tuggle, Katherine L.; Wainwright, Claire E.; De Boeck, Kris
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Sonic Hedgehog Signaling Is Essential for Pulmonary Ionocyte Specification in Human and Ferret Airway Epithelia
errAMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
IF5.3
err2023-09-01
err9
errOAAI
errCai, Qian; Luo, Meihui; Tang, Yinghua; Yu, Miao; Yuan, Feng; Gasser, Grace N.; Liu, Xiaoming; Engelhardt, John F.
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errSave
Orthotopic Ferret Tracheal Transplantation Using a Recellularized Bioengineered Graft Produces Functional Epithelia
errBIOENGINEERING-BASEL
IF3.7
err2023-06-29
err1
errOAAI
errPai, Albert C. C.; Swatek, Anthony M.; Lynch, Thomas J.; Ahlers, Bethany A.; Ievlev, Vitaly; Engelhardt, John F.; Parekh, Kalpaj R.
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errSave
Cystic Fibrosis-Related Diabetes Workshop: Research Priorities Spanning Disease Pathophysiology, Diagnosis, and Outcomes
errDIABETES
IF7.5
err2023-05-01
err8
errOAAI
errPutman, Melissa S.; Norris, Andrew W.; Hull, Rebecca L.; Rickels, Michael R.; Sussel, Lori; Blackman, Scott M.; Chan, Christine L.; Ode, Katie Larson; Daley, Tanicia; Stecenko, Arlene A.; Moran, Antoinette; Helmick, Meagan J.; Cray, Sharon; Alvarez, Jessica A.; Stallings, Virginia A.; Tuggle, Katherine L.; Clancy, John P.; Eggerman, Thomas L.; Engelhardt, John F.; Kelly, Andrea
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Cloning a profibrotic stem cell variant in idiopathic pulmonary fibrosis
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2023-04-26
err6
errOAAI
errWang, Shan; Rao, Wei; Hoffman, Ashley; Lin, Jennifer; Li, Justin; Lin, Tao; Liew, Audrey-Ann; Vincent, Matthew; Mertens, Tinne C. J.; Karmouty-Quintana, Harry; Crum, Christopher P.; Metersky, Mark L.; Schwartz, David A.; Davies, Peter J. A.; Stephan, Clifford; Jyothula, Soma S. K.; Sheshadri, Ajay; Suarez, Erik Eddie; Huang, Howard J.; Engelhardt, John F.; Dickey, Burton F.; Parekh, Kalpaj R.; McKeon, Frank D.; Xian, Wa
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errSave
Development and characterization of ferret ex vivo tracheal injury and cell engraftment model
errFRONTIERS IN MEDICINE
IF3
err2023-04-11
err0
errOAAI
errIevlev, Vitaly; Pai, Albert C.; Dillon Jr, Drew S.; Kuhl, Spencer; Lynch, Thomas J.; Freischlag, Kyle W.; Gries, Caitlyn B.; Engelhardt, John F.; Parekh, Kalpaj R.
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errSave
Bile acid regulation of C/EBPβ, CREB, and c-Jun function, via the extracellular signal-regulated kinase and c-Jun NH2-terminal kinase pathways, modulates the apoptotic response of hepatocytes
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err151
errOAAI
errQiao, L; Han, SI; Fang, YW; Park, JS; Gupta, S; Gilfor, D; Amorino, G; Valerie, K; Sealy, L; Engelhardt, JF; Grant, S; Hylemon, PB; Dent, P
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errSave
PITX2 and β-catenin interactions regulate lef-1 isoform expression
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err88
errOAAI
errAmen, Melanie; Liu, Xiaoming; Vadlamudi, Usha; Elizondo, Gabriela; Diamond, Evan; Engelhardt, John F.; Amendt, Brad A.
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errSave
Evidence for a superoxide permeability pathway in endosomal membranes
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err91
errOAAI
errMumbengegwi, Davis R.; Li, Qiang; Li, Canhui; Bear, Christine E.; Engelhardt, John F.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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Róbert Langer
H-index: 262 · Papers: 2.0K
J
James M. Wilson
H-index: 155 · Papers: 1.4K
M
Michael J. Welsh
H-index: 143 · Papers: 669
T
Timothy R. Billiar
H-index: 140 · Papers: 1.2K
D
Daniel G. Anderson
H-index: 128 · Papers: 470
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