Not logged in Real-world treatment patterns and subsequent treatment effectiveness following frontline brigatinib in the ALTA-1L trial Ahn, Myung-Ju; Delmonte, Angelo; Ghosh, Sharmistha; Hochmair, Maximilian; Yang, Tsung-Ying; Yang, James Chih-Hsin; Han, Ji-Youn; Hansen, Karin Holmskov; Wu, Yanyu; Wan, Yin; Lin, Huamao Mark; Kretz, Julian; Hupf, Bradley; Kurec, Ahmet Melih; Churchill, Eric N.; Fram, Robert J.; Cabasag, Citadel Jungco; Goriya, Vishal; Zhao, Yuzhe; Campelo, Maria Rosario Garcia Share Save
A phase 1 study to assess the absolute bioavailability, mass balance, pharmacokinetics, metabolism, and excretion of [14C]-mobocertinib, an oral inhibitor of EGFR exon 20 insertion mutations, in healthy participants Hanley, Michael J.; Zhang, Steven; Griffin, Robert; Zhu, Sean Xiaochun; Fram, Robert J.; Lin, Jianchang; Venkatakrishnan, Karthik; Gupta, Neeraj Share Save
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Clinical validation of a multiplex polymerase chain reaction (mPCR) assay to identify patients (pts) with NSCLC suitable for mobocertinib treatment Zhou, C.; Li, B.; Fang, J.; Zhou, J.; Hu, Y.; Zhu, C.; Bunn, V.; Lin, M.; Hong, J-L.; Huang, J.; Wang, J.; Fram, R. J.; Vincent, S.; Li, Y. Share Save
EXCLAIM-2: Phase III trial of first-line (1L) mobocertinib versus platinum-based chemotherapy in patients (pts) with epidermal growth factor receptor (EGFR) exon 20 insertion (ex20ins)+ locally advanced/ metastatic NSCLC Janne, P. A.; Wang, B-C.; Cho, B. C.; Zhao, J.; Li, J.; Hochmair, M. J.; Peters, S.; Besse, B.; Kato, T.; Wu, Y-L.; Nguyen, D.; Lin, J.; Lin, J.; Vranceanu, F.; Lin, M.; Fram, R. J.; Mok, T. S. K. Share Save
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Time without transfusion reliance: a novel patient-centric metric for new therapies in myelodysplastic syndromes Zeidner, Joshua F.; Mazerolle, Flora; Norton, Jonathan; Regnault, Antoine; Kristo, Fjoralba; Romero, Heather; Fram, Robert J.; V. Faller, Douglas; Dalal, Mehul; Ades, Lionel; Sekeres, Mikkael A. Share Save
Pevonedistat plus azacitidine vs azacitidine alone in higher-risk MDS/chronic myelomonocytic leukemia or low-blast-percentage AML Ades, Lionel; Girshova, Larisa; Doronin, Vadim A.; Diez-Campelo, Maria; Valcarcel, David; Kambhampati, Suman; Viniou, Nora-Athina; Woszczyk, Dariusz; De Paz Arias, Raquel; Symeonidis, Argiris; Anagnostopoulos, Achilles; Ciliao Munhoz, Eduardo; Platzbecker, Uwe; Santini, Valeria; Fram, Robert J.; Yuan, Ying; Friedlander, Sharon; Faller, Douglas, V; Sekeres, Mikkael A. Share Save
Randomized phase 2 trial of pevonedistat plus azacitidine versus azacitidine for higher-risk MDS/CMML or low-blast AML (vol 35, pg 2119, 2021) Sekeres, Mikkael A.; Watts, Justin; Radinoff, Atanas; Sangerman, Montserrat Arnan; Cerrano, Marco; Lopez, Patricia Font; Zeidner, Joshua F.; Campelo, Maria Diez; Graux, Carlos; Liesveld, Jane; Selleslag, Dominik; Tzvetkov, Nikolay; Fram, Robert J.; Zhao, Dan; Bell, Jill; Friedlander, Sharon; Faller, Douglas V.; Ades, Lionel Share Save
Randomized phase 2 trial of pevonedistat plus azacitidine versus azacitidine for higher-risk MDS/CMML or low-blast AML Sekeres, Mikkael A.; Watts, Justin; Radinoff, Atanas; Sangerman, Montserrat Arnan; Cerrano, Marco; Lopez, Patricia Font; Zeidner, Joshua F.; Campelo, Maria Diez; Graux, Carlos; Liesveld, Jane; Selleslag, Dominik; Tzvetkov, Nikolay; Fram, Robert J.; Zhao, Dan; Bell, Jill; Friedlander, Sharon; Faller, Douglas V.; Ades, Lionel Share Save
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Phase I study of XMT-1001, a novel water soluble camptothecin conjugate, given as an intravenous infusion once every three weeks to patients with advanced solid tumors Sausville, Edward A.; Garbo, Lawrence; Weiss, Glen J.; Shkolny, Dana; Yurkovetskiy, Alexander V.; Bethune, Claudette; Ramanathan, Ramesh K.; Fram, Robert J. Share Save
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Novel inosine monophosphate dehydrogenase inhibitor VX-944 induces apoptosis in multiple myeloma cells primarily via caspase-independent AIF/Endo G pathway Ishitsuka, K; Hideshima, T; Hamasaki, M; Raje, N; Kumar, S; Podar, K; Le Gouill, S; Shiraishi, N; Yasui, H; Roccaro, AM; Tai, YZ; Chauhan, D; Fram, R; Tamura, K; Jain, J; Anderson, KC Share Save
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