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Hemorrhage Sites and Mitigation Strategies After Pancreaticoduodenectomy Preston, William A.; Collins, Micaela L.; Goenen, Mithat; Murtha, Timothy; Rivera, Victor; Lamm, Ryan; Schafer, Michelle; Yarmohammadi, Hooman; Covey, Anne; Brody, Lynn A.; Topper, Stephen; Nevler, Avinoam; Lavu, Harish; Yeo, Charles J.; Balachandran, Vinod P.; Drebin, Jeffrey A.; Soares, Kevin C.; Wei, Alice C.; Kingham, T. Peter; D'Angelica, Michael I.; Jarnagin, William R. Share Save
Preclinical characterization of THE-349, a mutant-selective, CNS-active, fourth-generation EGFR inhibitor to overcome T790M-and C797S-mediated resistance in NSCLC Zhang, Sen; Nadworny, Sara; Huang, Wei-Sheng; Talbot, Adam; Ye, Emily; Narasimhan, Narayana; Shakespeare, William C.; Rivera, Victor M. Share Save
Excessive concentrations of kinase inhibitors in translational studies impede effective drug repurposing Liu, Chuan; Leighow, Scott M.; Mcilroy, Kyle; Lu, Mengrou; Dennis, Kady A.; Abello, Kerry; Brown, Donovan J.; Moore, Connor J.; Shah, Anushka; Inam, Haider; Rivera, Victor M.; Pritchard, Justin R. Share Save
Phase II Study of Ponatinib in Advanced Gastrointestinal Stromal Tumors: Efficacy, Safety, and Impact of Liquid Biopsy and Other Biomarkers George, Suzanne; von Mehren, Margaret; Fletcher, Jonathan A.; Sun, Jichao; Zhang, Sen; Pritchard, Justin R.; Hodgson, John Graeme; Kerstein, David; Rivera, Victor M.; Haluska, Frank G.; Heinrich, Michael C. Share Save
Targeting HER2 Exon 20 Insertion-Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib Han, Han; Li, Shuai; Chen, Ting; Fitzgerald, Michael; Liu, Shengwu; Peng, Chengwei; Tang, Kwan Ho; Cao, Shougen; Chouitar, Johara; Wu, Jiansheng; Peng, David; Deng, Jiehui; Gao, Zhendong; Baker, Theresa E.; Li, Fei; Zhang, Hua; Pan, Yuanwang; Ding, Hailin; Hu, Hai; Pyon, Val; Thakurdin, Cassandra; Papadopoulos, Eleni; Tang, Sittinon; Gonzalvez, Francois; Chen, Haiquan; Rivera, Victor M.; Brake, Rachael; Vincent, Sylvie; Wong, Kwok-Kin Share Save
Mobocertinib (TAK-788): A Targeted Inhibitor of EGFR Exon 20 Insertion Mutants in Non-Small Cell Lung Cancer Gonzalvez, Francois; Vincent, Sylvie; Baker, Theresa E.; Gould, Alexandra E.; Li, Shuai; Wardwell, Scott D.; Nadworny, Sara; Ning, Yaoyu; Zhang, Sen; Huang, Wei-Sheng; Hu, Yongbo; Li, Feng; Greenfield, Matthew T.; Zech, Stephan G.; Das, Biplab; Narasimhan, Narayana, I; Clackson, Tim; Dalgarno, David; Shakespeare, William C.; Fitzgerald, Michael; Chouitar, Johara; Griffin, Robert J.; Liu, Shengwu; Wong, Kwok-Kin; Zhu, Xiaotian; Rivera, Victor M. Share Save
Ultra-accurate Duplex Sequencing for the assessment of pretreatment ABL1 kinase domain mutations in Ph plus ALL Short, Nicholas J.; Kantarjian, Hagop; Kanagal-Shamanna, Rashmi; Sasaki, Koji; Ravandi, Farhad; Cortes, Jorge; Konopleva, Marina; Issa, Ghayas C.; Kornblau, Steven M.; Garcia-Manero, Guillermo; Garris, Rebecca; Higgins, Jake; Pratt, Gabriel; Williams, Lindsey N.; Valentine, Charles C., III; Rivera, Victor M.; Pritchard, Justin; Salk, Jesse J.; Radich, Jerald; Jabbour, Elias Share Save
Single-Molecule Sequencing Reveals Patterns of Preexisting Drug Resistance That Suggest Treatment Strategies in Philadelphia-Positive Leukemias Schmitt, Michael W.; Pritchard, Justin R.; Leighow, Scott M.; Aminov, Bella I.; Beppu, Lan; Kim, Daniel S.; Hodgson, J. Graeme; Rivera, Victor M.; Loeb, Lawrence A.; Radich, Jerald P. Share Save
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The Potent ALK Inhibitor Brigatinib (AP26113) Overcomes Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in Preclinical Models Zhang, Sen; Anjum, Rana; Squillace, Rachel; Nadworny, Sara; Zhou, Tianjun; Keats, Jeff; Ning, Yaoyu; Wardwell, Scott D.; Miller, David; Song, Youngchul; Eichinger, Lindsey; Moran, Lauren; Huang, Wei-Sheng; Liu, Shuangying; Zou, Dong; Wang, Yihan; Mohemmad, Qurish; Jang, Hyun Gyung; Ye, Emily; Narasimhan, Narayana; Wang, Frank; Miret, Juan; Zhu, Xiaotian; Clackson, Tim; Dalgarno, David; Shakespeare, William C.; Rivera, Victor M. Share Save
AP32788, a potent, selective inhibitor of EGFR and HER2 oncogenic mutants, including exon 20 insertions, in preclinical models Gonzalvez, Francois; Zhu, Xiaotian; Huang, Wei-Sheng; Baker, Theresa E.; Ning, Yaoyu; Wardwell, Scott D.; Nadworny, Sara; Zhang, Sen; Das, Biplab; Gong, Yongjin; Greenfield, Matthew T.; Jang, Hyun G.; Kohlmann, Anna; Li, Feng; Taslimi, Paul M.; Tugnait, Meera; Xu, Yongjin; Ye, Emily Y.; Youngsaye, Willmen W.; Zech, Stephan G.; Zhang, Yun; Zhou, Tianjun; Narasimhan, Narayana I.; Dalgarno, David C.; Shakespeare, William C.; Rivera, Victor M. Share Save
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Discovery of Brigatinib (AP26113), a Phosphine Oxide-Containing, Potent, Orally Active Inhibitor of Anaplastic Lymphoma Kinase Huang, Wei-Sheng; Liu, Shuangying; Zou, Dong; Thomas, Mathew; Wang, Yihan; Zhou, Tianjun; Romero, Jan; Kohlmann, Anna; Li, Feng; Qi, Jiwei; Cai, Lisi; Dwight, Timothy A.; Xu, Yongjin; Xu, Rongsong; Dodd, Rory; Toms, Angela; Parillon, Lois; Lu, Xiaohui; Anjum, Rana; Zhang, Sen; Wang, Frank; Keats, Jeffrey; Wardwell, Scott D.; Ning, Yaoyu; Xu, Qihong; Moran, Lauren E.; Mohemmad, Qurish K.; Jang, Hyun Gyung; Clackson, Tim; Narasimhan, Narayana I.; Rivera, Victor M.; Zhu, Xiaotian; Dalgarno, David; Shakespeare, William C. Share Save
Assessment of Brigatinib (AP26113) CNS Activity in Patients (Pts) With ALK plus NSCLC and intracranial metastases in a Phase 1/2 Study Camidge, D. R.; Bazhenova, L. A.; Salgia, R.; Langer, C. J.; Gold, K.; Rosell, R.; Shaw, A. T.; Weiss, G. J.; Dorer, D. J.; Rivera, V. M.; Conlan, M. G.; Kerstein, D.; Gettinger, S. N. Share Save
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Discovery of AP26113, a potent, orally active inhibitor of anaplastic lymphoma kinase and clinically relevant mutants Huang, Wei-Sheng; Li, Feng; Cai, Lisi; Xu, Yongjin; Zhang, Sen; Wardwell, Scott D.; Ning, Yaoyu; Kohlmann, Anna; Zhou, Tianjun; Ye, Emily Y.; Zhu, Xiaotian; Narasimhan, Narayana I.; Clackson, Tim; Rivera, Victor M.; Dalgarno, David; Shakespeare, William C. Share Save
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