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D

David Eisenberg

University of California System

139H-index
744Paper Count
8.6WCitation Count
Published Papers 158
Publication Date
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Genetic and structural aspects of amyloid diseases
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2025-10-01
err0
PREAI
errRosenberg, Gregory M.; Murray, Kevin A.; Sawaya, Michael R.; Jiang, Yi Xiao; Geschwind, Daniel H.; Eisenberg, David S.
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To what extent is Anfinsen’s Thermodynamic Hypothesis consistent with the formation and polymorphism of amyloid fibrils?
errJournal of Molecular Biology
IF4.5
err2025-07-30
err0
errOAAI
errYi Xiao Jiang; David S. Eisenberg
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errSave
How short peptides disassemble tau fibrils in Alzheimer’s disease
errNature
IF48.5
err2025-07-09
err0
PREAI
errKe Hou; Peng Ge; Michael R. Sawaya; Liisa Lutter; Joshua L. Dolinsky; Yuan Yang; Yi Xiao Jiang; David R. Boyer; Xinyi Cheng; Justin Pi; Jeffrey Zhang; Jiahui Lu; Romany Abskharon; Shixin Yang; Zhiheng Yu; Juli Feigon; David S. Eisenberg
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Amyloid Oligomers: Expediting Crystal Growth and Revisiting the Corkscrew Structures
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2025-05-21
err0
PREAI
errHirschbeck, Sarah S.; Sawaya, Michael R.; Lindberg, Edward T.; Limbach, Miranda N.; Jang, Joshua H.; Lazar Cantrell, Kristi L.; Eisenberg, David S.
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errSave
Liganded magnetic nanoparticles for magnetic resonance imaging of α-synuclein
errNPJ PARKINSONS DISEASE
IF8.2
err2025-04-23
err0
errOAAI
errPan, Hope; Balbirnie, Melinda; Hou, Ke; Maria, Naomi S. Sta; Sahay, Shruti; Denver, Paul; Lepore, Stefano; Jones, Mychica; Zuo, Xiaohong; Zhu, Chunni; Mirbaha, Hilda; Shahpasand-Kroner, Hedieh; Mekkittikul, Marisa; Lu, Jiahui; Hu, Carolyn J.; Cheng, Xinyi; Abskharon, Romany; Sawaya, Michael R.; Williams, Christopher K.; Vinters, Harry V.; Jacobs, Russell E.; Harris, Neil G.; Cole, Gregory M.; Frautschy, Sally A.; Eisenberg, David S.
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Amyloid nomenclature 2024: update, novel proteins, and recommendations by the International Society of Amyloidosis (ISA) Nomenclature Committee
errAMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS
IF7.4
err2024-09-30
err10
PREAI
errBuxbaum, Joel N.; Eisenberg, David S.; Faendrich, Marcus; McPhail, Ellen D.; Merlini, Giampaolo; Saraiva, Maria J. M.; Sekijima, Yoshiki; Westermark, Per
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D-peptide-magnetic nanoparticles fragment tau fibrils and rescue behavioral deficits in a mouse model of Alzheimer's disease
errSCIENCE ADVANCES
IF12.5
err2024-05-03
err2
errOAAI
errHou, Ke; Pan, Hope; Shahpasand-Kroner, Hedieh; Hu, Carolyn; Abskharon, Romany; Seidler, Paul; Mekkittikul, Marisa; Balbirnie, Melinda; Lantz, Carter; Sawaya, Michael R.; Dolinsky, Joshua L.; Jones, Mychica; Zuo, Xiaohong; Loo, Joseph A.; Frautschy, Sally; Cole, Greg; Eisenberg, David S.
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Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-02-01
err2
errOAAI
errLu, Jiahui; Ge, Peng; Sawaya, Michael R.; Hughes, Michael P.; Boyer, David R.; Cao, Qin; Abskharon, Romany; Cascio, Duilio; Tayeb-Fligelman, Einav; Eisenberg, David S.
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Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy
errNATURE COMMUNICATIONS
IF15.7
err2024-01-17
err11
errOAAI
errNguyen, Binh An; Singh, Virender; Afrin, Shumaila; Yakubovska, Anna; Wang, Lanie; Ahmed, Yasmin; Pedretti, Rose; Fernandez-Ramirez, Maria del Carmen; Singh, Preeti; Pekala, Maja; Hernandez, Luis O. Cabrera; Kumar, Siddharth; Lemoff, Andrew; Gonzalez-Prieto, Roman; Sawaya, Michael R.; Eisenberg, David S.; Benson, Merrill Douglas; Saelices, Lorena
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Fibril structures of TFG protein mutants validate the identification of TFG as a disease-related amyloid protein by the IMPAcT method
errPNAS NEXUS
IF3.8
err2023-11-20
err0
errOAAI
errRosenberg, Gregory M.; Abskharon, Romany; Boyer, David R.; Ge, Peng; Sawaya, Michael R.; Eisenberg, David S.
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Racemic Peptides from Amyloid β and Amylin Form Rippled β-Sheets Rather Than Pleated β-Sheets
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2023-11-16
err3
PREAI
errHazari, Amaruka; Sawaya, Michael R.; Sajimon, Maria; Vlahakis, Niko; Rodriguez, Jose; Eisenberg, David; Raskatov, Jevgenij A.
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Structure- based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2023-10-06
err12
errOAAI
errAbskharon, Romany; Pan, Hope; Sawaya, Michael R.; Seidler, Paul M.; Olivares, Eileen J.; Chen, Yu; Murray, Kevin A.; Zhang, Jeffrey; Lantz, Carter; Bentzel, Megan; Boyer, David R.; Cascio, Duilio; Nguyen, Binh A.; Hou, Ke; Cheng, Xinyi; Pardon, Els; Williams, Christopher K.; Nana, Alissa L.; V. Vinters, Harry; Spina, Salvatore; Grinberg, Lea T.; Seeley, William W.; Steyaert, Jan; Glabe, Charles G.; Loo, Rachel R. Ogorzalek; Loo, Joseph A.; Eisenberg, David S.
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Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils
errNATURE COMMUNICATIONS
IF15.7
err2023-04-25
err9
errOAAI
errTayeb-Fligelman, Einav; Bowler, Jeannette T.; Tai, Christen E. E.; Sawaya, Michael R.; Jiang, Yi Xiao; Garcia, Gustavo; Griner, Sarah L.; Cheng, Xinyi; Salwinski, Lukasz; Lutter, Liisa; Seidler, Paul M.; Lu, Jiahui; Rosenberg, Gregory M.; Hou, Ke; Abskharon, Romany; Pan, Hope; Zee, Chih-Te; Boyer, David R.; Li, Yan; Anderson, Daniel H.; Murray, Kevin A.; Falcon, Genesis; Cascio, Duilio; Saelices, Lorena; Damoiseaux, Robert; Arumugaswami, Vaithilingaraja; Guo, Feng; Eisenberg, David S.
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Small molecules disaggregate alpha-synuclein and prevent seeding from patient brain-derived fibrils
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2023-02-09
err17
errOAAI
errMurray, Kevin A.; Hu, Carolyn J.; Pan, Hope; Lu, Jiahui; Abskharon, Romany; Bowler, Jeannette T.; Rosenberg, Gregory M.; Williams, Christopher K.; Elezi, Gazmend; Balbirnie, Melinda; Faull, Kym F.; Vinters, Harry V.; Seidler, Paul M.; Eisenberg, David S.
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errSave
The Identification of Mutations Promoting Amyloidogenic Transitions (IMPAcT) method for identification of previously unrecognized amyloid disease-related proteins
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-01-01
err0
errOAAI
errRosenberg, Gregory; Murray, Kevin; Salwinski, Lukasz; Hughes, Michael; Abskharon, Romany; Eisenberg, David
errShare
errSave
Amyloid nomenclature 2022: update, novel proteins, and recommendations by the International Society of Amyloidosis (ISA) Nomenclature Committee
errAMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS
IF7.4
err2022-11-24
err184
errOAAI
errBuxbaum, Joel N.; Dispenzieri, Angela; Eisenberg, David S.; Faendrich, Marcus; Merlini, Giampaolo; Saraiva, Maria J. M.; Sekijima, Yoshiki; Westermark, Per
errShare
errSave
Micro-electron diffraction structure of the aggregation-driving N terminus of Drosophila neuronal protein Orb2A reveals amyloid-like β-sheets
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2022-10-01
err6
errOAAI
errBowler, Jeannette T.; Sawaya, Michael R.; Boyer, David R.; Cascio, Duilio; Bali, Manya; Eisenberg, David S.
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errSave
Structure-based discovery of small molecules that disaggregate Alzheimer's disease tissue derived tau fibrils in vitro
errNATURE COMMUNICATIONS
IF15.7
err2022-09-16
err82
errOAAI
errSeidler, Paul M.; Murray, Kevin A.; Boyer, David R.; Ge, Peng; Sawaya, Michael R.; Hu, Carolyn J.; Cheng, Xinyi; Abskharon, Romany; Pan, Hope; DeTure, Michael A.; Williams, Christopher K.; Dickson, Dennis W.; Vinters, Harry V.; Eisenberg, David S.
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errSave
De novo designed protein inhibitors of amyloid aggregation and seeding
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2022-08-15
err42
errOAAI
errMurray, Kevin A.; Hu, Carolyn J.; Griner, Sarah L.; Pan, Hope; Bowler, Jeannette T.; Abskharon, Romany; Rosenberg, Gregory M.; Cheng, Xinyi; Seidler, Paul M.; Eisenberg, David S.
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errSave
Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2022-05-30
err15
errOAAI
errMurray, Kevin A.; Hughes, Michael P.; Hu, Carolyn J.; Sawaya, Michael R.; Salwinski, Lukasz; Pan, Hope; French, Samuel W.; Seidler, Paul M.; Eisenberg, David S.
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Research Directions

No research directions
Co-authors
Cooperation Journals
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Chris Sander
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