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Robert A. Beagrie

university of oxford
H-index:14
Citation Count:1,326
Views:0

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Loop extrusion by cohesin plays a role in enhancer-activated gene expression early in differentiation

凝聚素介导的环化挤出在分化早期增强子激活基因表达中发挥作用

Nature Communications
IF15.7
2026-05-260
OAAI
Rosa J. Stolper; Felice H. Tsang; Emily Georgiades; Lars L. P. Hanssen; Edward A. J. Tunnacliffe; Damien J. Downes; Caroline L. Harrold; Jim R. Hughes; Robert A. Beagrie; Benjamin Davies; Mira T. Kassouf; Douglas R. Higgs
Multiplex-GAM: genome-wide identification of chromatin contacts yields insights overlooked by Hi-C
NATURE METHODS
IF32.1
2023-06-198
OAAI
Beagrie, Robert A. A.; Thieme, Christoph J. J.; Annunziatella, Carlo; Baugher, Catherine; Zhang, Yingnan; Schueler, Markus; Kukalev, Alexander; Kempfer, Rieke; Chiariello, Andrea M. M.; Bianco, Simona; Li, Yichao; Davis, Trenton; Scialdone, Antonio; Welch, Lonnie R. R.; Nicodemi, Mario; Pombo, Ana
Pathogenic human variant that dislocates GATA2 zinc fingers disrupts hematopoietic gene expression and signaling networks
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2023-04-035
OAAI
Jung, Mabel Minji; Shen, Siqi; Botten, Giovanni A.; Olender, Thomas; Katsumura, Koichi R.; Johnson, Kirby D.; Soukup, Alexandra A.; Liu, Peng; Zhang, Qingzhou; Jensvold, Zena D.; Lewis, Peter W.; Beagrie, Robert A.; Low, Jason K. K.; Yang, Lihua; Mackay, Joel P.; Godley, Lucy A.; Brand, Marjorie; Xu, Jian; Keles, Sunduz; Bresnick, Emery H.
Gene silencing dynamics are modulated by transiently active regulatory elements
MOLECULAR CELL
IF16.6
2023-03-016
OAAI
Vermunt, Marit W.; Luan, Jing; Zhang, Zhe; Thrasher, A. Josephine; Huang, Anran; Saari, Megan S.; Khandros, Eugene; Beagrie, Robert A.; Zhang, Shiping; Vemulamada, Pranay; Brilleman, Matilda; Lee, Kiwon; Yano, Jennifer A.; Giardine, Belinda M.; Keller, Cheryl A.; Hardison, Ross C.; Blobel, Gerd A.
Making connections: enhancers in cellular differentiation
TRENDS IN GENETICS
IF16.3
2022-04-015
PRE
Herrmann, Jennifer C.; Beagrie, Robert A.; Hughes, Jim R.
Reactivation of a developmentally silenced embryonic globin gene
NATURE COMMUNICATIONS
IF15.7
2021-07-2122
OAAI
King, Andrew J.; Songdej, Duantida; Downes, Damien J.; Beagrie, Robert A.; Liu, Siyu; Buckley, Megan; Hua, Peng; Suciu, Maria C.; Oudelaar, A. Marieke; Hanssen, Lars L. P.; Jeziorska, Danuta; Roberts, Nigel; Carpenter, Stephanie J.; Francis, Helena; Telenius, Jelena; Olijnik, Aude-Anais; Sharpe, Jacqueline A.; Sloane-Stanley, Jacqueline; Eglinton, Jennifer; Kassouf, Mira T.; Orkin, Stuart H.; Pennacchio, Len A.; Davies, James O. J.; Hughes, Jim R.; Higgs, Douglas R.; Babbs, Christian
The mouse alpha-globin cluster: a paradigm for studying genome regulation and organization
CURRENT OPINION IN GENETICS & DEVELOPMENT
IF3.6
2021-04-0118
OAAI
Oudelaar, A. Marieke; Beagrie, Robert A.; Kassouf, Mira T.; Higgs, Douglas R.
Enhancers predominantly regulate gene expression during differentiation via transcription initiation
MOLECULAR CELL
IF16.6
2021-03-0133
OAAI
Larke, Martin S. C.; Schwessinger, Ron; Nojima, Takayuki; Telenius, Jelena; Beagrie, Robert A.; Downes, Damien J.; Oudelaar, A. Marieke; Truch, Julia; Graham, Bryony; Bender, M. A.; Proudfoot, Nicholas J.; Higgs, Douglas R.; Hughes, Jim R.
High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale
NATURE COMMUNICATIONS
IF15.7
2021-01-2222
OAAI
Downes, Damien J.; Beagrie, Robert A.; Gosden, Matthew E.; Telenius, Jelena; Carpenter, Stephanie J.; Nussbaum, Lea; De Ornellas, Sara; Sergeant, Martin; Eijsbouts, Chris Q.; Schwessinger, Ron; Kerry, Jon; Roberts, Nigel; Shivalingam, Arun; El-Sagheer, Afaf; Oudelaar, A. Marieke; Brown, Tom; Buckle, Veronica J.; Davies, James O. J.; Hughes, Jim R.
Hypoxia Induces Transcriptional and Translational Downregulation of the Type I IFN Pathway in Multiple Cancer Cell Types

缺氧诱导多种癌细胞类型中I型IFN途径的转录和翻译下调

CANCER RESEARCH
IF16.6
2020-12-0262
OAAI
Miar, Ana; Arnaiz, Esther; Bridges, Esther; Beedie, Shaunna; Cribbs, Adam P.; Downes, Damien J.; Beagrie, Robert A.; Rehwinkel, Jan; Harris, Adrian L.
Recapitulation of erythropoiesis in congenital dyserythropoietic anemia type I (CDA-I) identifies defects in differentiation and nucleolar abnormalities
HAEMATOLOGICA
IF7.9
2020-10-2910
OAAI
Scott, Caroline; Downes, Damien J.; Brown, Jill M.; Beagrie, Robert; Olijnik, Aude-Anais; Gosden, Matthew; Schwessinger, Ron; Fisher, Christopher A.; Rose, Anna; Ferguson, David J. P.; Johnson, Errin; Hill, Quentin A.; Okoli, Steven; Renella, Raffaele; Ryan, Kate; Brand, Marjorie; Hughes, Jim; Roy, Noemi B. A.; Higgs, Douglas R.; Babbs, Christian; Buckle, Veronica J.
Dynamics of the 4D genome during in vivo lineage specification and differentiation
NATURE COMMUNICATIONS
IF15.7
2020-06-0170
OAAI
Oudelaar, A. Marieke; Beagrie, Robert A.; Gosden, Matthew; de Ornellas, Sara; Georgiades, Emily; Kerry, Jon; Hidalgo, Daniel; Carrelha, Joana; Shivalingam, Arun; El-Sagheer, Afaf H.; Telenius, Jelena M.; Brown, Tom; Buckle, Veronica J.; Socolovsky, Merav; Higgs, Douglas R.; Hughes, Jim R.
Continuous chromatin changes
NATURE
IF48.5
2017-07-0610
OAAI
Beagrie, Robert A.; Pombo, Ana
Examining Topological Domain Influence on Enhancer Function
DEVELOPMENTAL CELL
IF8.7
2016-12-012
OAAI
Beagrie, Robert A.; Pombo, Ana
Gene activation by metazoan enhancers: Diverse mechanisms stimulate distinct steps of transcription

后生动物增强子激活基因: 多种机制刺激转录的不同步骤

BIOESSAYS
IF2.7
2016-07-2547
OAAI
Beagrie, Robert A.; Pombo, Ana

Research Directions

The data has not been retrieved yet.
J
Jim R. Hughes
H-index:56Papers:219Citations:1.2万
D
Douglas R. Higgs
H-index:98Papers:461Citations:3.2万
D
Damien J. Downes
H-index:29Papers:87Citations:2,989
A
A. Marieke Oudelaar
H-index:25Papers:69Citations:3,188
A
Ana Pombo
H-index:51Papers:183Citations:1.4万
J
Jelena Telenius
H-index:27Papers:62Citations:2,961
R
Ron Schweßinger
H-index:18Papers:64Citations:1,739
V
Veronica J. Buckle
H-index:51Papers:166Citations:9,062
M
Mira Kassouf
H-index:13Papers:39Citations:1,395
M
Matthew Gosden
H-index:13Papers:25Citations:985