未登录 Small Molecule-Controlled Gene Expression: Design of Drug-like High-Affinity Modulators of a Custom-Made Riboswitch 小分子控制的基因表达: 定制核糖开关的药物样高亲和力调节剂的设计 Hedwig, Vera; Sporing, Maike; Aspnes, Gary; Gottschling, Dirk; Klein, Holger; Klugmann, Matthias; Kreuz, Sebastian; Ries, Benjamin; Schnapp, Gisela; Scharsich, Sandra; Hartig, Jorg S.; Hucke, Oliver 分享 收藏
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SOS1 inhibition suppresses the emergence of osimertinib resistance to generate a durable response in EGFR-mutant lung cancer SOS1抑制可抑制奥希替尼耐药性的产生，从而在EGFR突变型肺癌中产生持久的疗效。 Daley, Brianna R.; Theard, Patricia L.; Hughes, Jacob M.; Finniff, Bridget A.; Hofmann, Marco H.; Kostyrko, Kaja; Schenk, Robyn L.; Vieira, Heidi M.; Askew, James W.; Lewis, Robert E.; Kortum, Robert L. 分享 收藏
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Predictive AI in Clinical Pharmacology: A Call to Action to Develop Robust Benchmarking Practices 临床药理学中的预测性人工智能：呼吁采取行动，开发稳健的基准测试实践 Ponce-bobadilla, Ana Victoria; Bram, Dominic; Farnoud, Ali; Frohlich, Holger; Janssen, Alexander; Korsbo, Niklas; Lindauer, Klaus; Raimundez, Elba; Saini, Anuraag; Stodtmann, Sven; Valderrama, Diego; Balling, Kristoffer Winther; Knochel, Jane; Mensing, Sven 分享 收藏
Machine learning-enabled systematic review on coded healthcare data in heart failure research 基于机器学习的系统性综述：心力衰竭研究中编码医疗数据的分析 Champsi, Asgher; Slater, Karin T.; Gill, Simrat; Dyszynski, Tomasz; Schroder, Megan; Suzart-Woischnik, Kiliana; Tyl, Benoit; Allee, Guillaume; Sartorius, Alfonso; Lumbers, R. Thomas; Asselbergs, Folkert W.; Grobbee, Diederick E.; Gkoutos, Georgios; Kotecha, Dipak 分享 收藏
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Translational and clinical development of therapeutic siRNA and ASOs: current industry practices, perspectives, and recommendations 治疗性siRNA和ASOs的转化与临床开发：当前行业实践、观点和建议 Christensen, Jesper Kammersgaard; Colletti, Nicholas; Hooshfar, Shirin; Jiang, Rongrong(Rosa); Kuo, Carol; Lindmark, Bosse; Lumen, Annie; Youssef, Amir S.; Albertolle, Matthew; Aluri, Krishna C.; Chen, Linzhi; Chen, Jingxian; Chopda, Girish; Chua, Xien Yu; Morais, Pedro; Dubois, Barent; Gibbons, Francis (Frank); Gudey, Shyam Kumar; Gupta, Swati; Hood, Steve; Humphreys, Sara; Husser, Christophe; Huth, Felix; Jani, Darshana; Jian, Wenying; Kakuda, Thomas; Kurz, Jeffrey; Linnebjerg, Helle; Liu, Jing; Lohmann, Sabine; Niu, Tao; Root, Katharina; Singla, Sumeet; Tang, Chenxiao; Veluri, Ravikanth; Zhang, Guangnong (Sunny); Zhang, Steven; Jawa, Vibha 分享 收藏
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Diagnosis challenges for chronic kidney disease in Irish primary care: a real-world study comparing eGFR, uACR and diagnosis coding in 66 Irish general practices 爱尔兰初级保健中慢性肾脏病的诊断挑战：一项比较66家爱尔兰全科诊所中eGFR、uACR和诊断编码的真实世界研究 Jin, Danyao; Rabe, Adrian; Coughlan, Aoife; Ryan, Emma; Induruwa, Isuru; van Hecke, Benjamin; Gumbs, Pearl; Jacob, Benjamin; Eyers, Keelan; Rajput, Kushagra; Bailey, Donal 分享 收藏
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Safety, Pharmacokinetics, and Pharmacodynamics of BI 1595043, a Selective Vanin Inhibitor, in Phase 1 Clinical Trials Involving Healthy Volunteers 安全性、药代动力学和药效动力学：BI 1595043（一种选择性瓦宁抑制剂）在涉及健康志愿者的I期临床试验中的研究 Kukreja, Anjli; Keller, Sascha; Shatillo, Yury; Bauer, Andras; Sharma, Ashish; Wojciekowski, Stephan; Visvanathan, Sudha; Aslanyan, Stella 分享 收藏
Bacterial Glutamine Synthetases as a Novel Metabolic Selection Marker to Improve CHO Cell Culture Performance Through Selection Stringency Modulation 细菌谷氨酰胺合成酶作为新型代谢选择标记，通过选择严格度调控改善CHO细胞培养性能 Heinzelmann, Daniel; Michelarakis, Nicholas; Reuss, Franziska; Lindner, Benjamin; Karow-Zwick, Anne R.; Bauer, Joschka; Renner, Benjamin; Fischer, Simon; Schulz, Patrick; Schmidt, Moritz 分享 收藏
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Lung function and skin fibrosis changes as predictors of survival in SSc-associated interstitial lung disease: a EUSTAR study 肺功能与皮肤纤维化变化作为SSc相关间质性肺病的生存预测指标：一项EUSTAR研究 Sobanski, Vincent; de Vries-Bouwstra, Jeska; Hoffmann-Vold, Anna-Maria; Huscher, Doerte; Alves, Margarida; Matucci-Cerinic, Marco; Riemekasten, Gabriela; Li, Mengtao; Czirjak, Laszlo; Kowal-Bielecka, Otylia; Allanore, Yannick; Schoof, Nils; Distler, Oliver 分享 收藏
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