Merck & Company

学者数1.8W

论文数8.7K

被引数2.9K

关联论文 (2922)

发表时间

Healthcare Resource Utilization and Medical Costs in Pulmonary Arterial Hypertension Management in Japan: A Retrospective Study Using a Claims Database 日本肺动脉高压管理中的医疗资源利用和医疗费用：一项基于理赔数据库的回顾性研究

Pulmonary Therapy

IF3

2026-02-01

OAAI

Tajima, Atsushi; Arai, Yoko; Nakamura, Takao; Tokita, Shigeru; Watzker, Anna; Sugiyama, Takumi; Emoto, Noriaki

Cost-effectiveness analysis of the use of PNEU-C-21 in adults aged ≥50 years in Canada

EXPERT REVIEW OF VACCINES

IF4.8

2026-01-22

PREAI

Mueller, Peter P.; Meilleur, Marie-Claude; Yi, Zinan; Martino, Amanda; Owusu-Edusei, Kwame

Real-world treatment patterns, recurrence, and overall survival of patients with muscle-invasive bladder cancer undergoing radical cystectomy in US oncology practice 美国临床实践中接受根治性膀胱切除术的肌层浸润性膀胱癌患者的真实世界治疗模式、复发和总生存情况

Urologic Oncology-Seminars and Original Investigations

IF2.3

2026-01-01

PREAI

Squires, Patrick; Coutinho, Francesca; Tepsick, Jon G.; Rogiers, Aljosja; Ramamurthy, Chethan; Li, Haojie; Morgan, Todd M.

In Situ Microscopy for Real-Time Visualization of Microcarrier Cell Cultures for Live Virus Vaccine Process Development 用于实时可视化病毒疫苗工艺开发的微载体细胞培养物的原位显微镜

BIOTECHNOLOGY AND BIOENGINEERING

IF3.6

2026-01-01

PREAI

Lomont, Justin P.; Love, Tracy N.; Wagner, James M.; Ralbovsky, Nicole M.; Smith, Joseph P.

Sustained symptomatic relief and disease clearance through 50 weeks of treatment with tulisokibart in participants with moderately to severely active ulcerative colitis in the phase 2 ARTEMIS-UC study 在ARTEMIS-UC 2期研究中，中度至重度活动性溃疡性结肠炎患者接受50周托利索基bart治疗可获持续症状缓解和疾病清除

Journal of Crohns & Colitis

IF8.7

2026-01-01

PREAI

Ma, C.; Boland, B.; Leszczyszyn, J.; Xu, Z. J.; Shao, J.; Feagan, B. G.

Streamlined neutralizing antibody assay development: overcoming serum interference, utilization of DOE and automation 简化中和抗体检测方法开发：克服血清干扰、利用实验设计和自动化

Bioanalysis

IF1.8

2026-01-01

PREAI

Pham, Kelly Ngoc; Bano, Nazneen; Rubinstein, Leonard J.; Schiller, James; Seghezzi, Wolfgang; Vazvaei-Smith, Faye; Xu, Weifeng

Affibody-based optical imaging probe for noninvasive detection of liver fibrosis 基于Affibody的光学成像探针用于无创检测肝纤维化

Theranostics

IF13.3

2026-01-01

PREAI

Sadabad, Raana Kashfi; Marinec, Paul Stephen; Lechuga, Lawrence; Thompson, Robert; Cheng, Ran; Saigal, Ashmita; Vinales, Irodiel; Martinez, Salomon; Solis, Allan Eduardo; Newman, Emily Melody Tso; Goncin, Una; Novotny, Christopher; Miller, Corey; Chin, Chih-Liang

Catalyzing change in MID3 through globalization, education, and innovation 通过全球化、教育和创新促进MID3变革

Journal of Pharmacokinetics and Pharmacodynamics

IF2.8

2025-12-16

PREAI

Chung, Douglas W.; Ait-Oudhia, Sihem; Chung, Doug

Epidemiology of metabolic dysfunction-associated steatotic liver disease/metabolic dysfunction-associated steatohepatitis and associated cardiometabolic factors in adults in China (2013-2023): A systematic review and meta-analysis 中国成人中代谢功能障碍相关脂肪性肝病/代谢功能障碍相关脂肪性肝炎的流行病学及其相关 cardiometabolic 因素 (2013-2023)：一项系统评价和 meta 分析

World Journal of Gastroenterology

IF5.4

2025-12-14

PREAI

Chai, Shang-Yu; Zhang, Ru-Ya; Fernandes, Gail; Zheng, Yi-Man; Wei, Lai

Scientific and Regulatory Policy Committee Points to Consider*: Sample Selection, Assay Design, Data Generation and Interpretation, and Reporting Practices for Chromogenic Immunohistochemical (IHC) Assays in Nonclinical Drug Development 科学和监管政策委员会考虑要点*: 样本选择、检测试剂盒设计、数据生成与解释以及报告实践，用于非临床药物开发中的显色免疫组织化学（IHC）检测试剂盒

Toxicologic Pathology

IF1.8

2025-12-01

PREAI

Aeffner, Famke; Bolon, Brad; Boyle, Molly H.; Buetow, Bernard S.; Forest, Thomas; Janardhan, Kyathanahalli; Mansfield, Keith; Meyerholz, David K.; Price, Shari; Rebelatto, Marlon C.

Pre-clinicial evaluation of a 9 valent human papilloma virus vaccine (9vHPV) with empty lipid nanoparticles (eLNPs) or chitosan adjuvants

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Sullivan, Nicole L.; Bilello, John; Cejas, Pedro; Citron, Michael; Mahan, Elizabeth A.; Kim, Sam-moon; Danziger, Andrew; Wolf, Mary; Thambi, Nithya; Shardar, Mohammed; Atuheirwe, Maxine; Liu, Yaping; Espeseth, Amy; Walford, Geoffrey; Bett, Andrew

Real-world treatment patterns and clinical outcomes of patients with treatment-naïve and relapsed/refractory diffuse large B-cell lymphoma in the United States 美国治疗初治和复发/难治性弥漫大B细胞淋巴瘤患者的真实世界治疗模式与临床结局

LEUKEMIA RESEARCH

IF2.2

2025-11-01

PREAI

Lue, Jennifer K.; Bobbili, Priyanka J.; Garg, Mahek; Yee, Christopher W.; Ryland, Katherine E.; Gupta, Sonia; Liu, Daisy; Raut, Monika; Duh, Mei Sheng

Prevalence and characteristics of metabolic dysfunction-associated steatohepatitis among pediatric patients in the MarketScan Databases

PLOS ONE

IF2.6

2025-10-27

PREAI

Peter-Marske, Kennedy M.; Zhang, Xiao; Wang, Tongtong; Liu, Xinyue; Fernandes, Gail; Engel, Samuel S.; Shankar, Ravi

Asymmetric Synthesis of MK-7845, an Investigational Treatment for COVID-19 MK-7845的不对称合成，新型冠状病毒肺炎的研究性治疗

ORGANIC LETTERS

IF5

2025-10-01

PREAI

Larson, Reed T.; Turnbull, Ben W. H.; Moon, Patrick J.; Lehnherr, Dan; Hughes, Jonathan M. E.; Popov, Stasik; Brito, Gilmar A.; Andreani, Teresa; Kim, Suhong; Herbort, James; Sifri, Renee J.; Badir, Shorouk O.; Onyeagusi, Chibueze I.; Deprez, Nicholas R.; Otte, Douglas; Gauthier, Donald R.; Kuhl, Nadine; Ji, Yining; Neel, Andrew J.; Cohen, Ryan D.; Derrick, Jeffrey S.; Bottecchia, Cecilia; Hartmanshenn, Clara; Vargas, David A.; Dal Poggetto, Guilherme; Confer, Alex M.; Zheng, Michelle; Qin, Yangzhong; Vikram, Ajit; Newman, Justin A.; Sakhaei, Zeinab; Drout, Riki J.; Chen, Lu; Wu, Zheng; Castro, Steve; Betancourt, Stella K.; Longia, Gurpreet; Kassim, Brittany; Xu, Yingju; Dunn, Jamie M. McCabe; Marzijarani, Nastaran Salehi

On the effects of differential scalar relaxation and chemical exchange in perfect echo NMR spectroscopy of AX spin systems 关于差分标量弛豫和化学交换在AX自旋系统完美回波NMR光谱学中的效应

JOURNAL OF MAGNETIC RESONANCE

IF1.9

2025-10-01

PREAI

Khirich, Gennady; Dal Poggetto, Guilherme; Augustine, Matthew P.

Application of Direct Inject Liquid Chromatography (DILC) as Real-Time Process Analytical Technology for Flow Reactions 直接注入液相色谱（DILC）作为流反应实时过程分析技术的应用

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2025-10-01

PREAI

Ji, Yining; Ayesa, Umme; Levesque, Francois; Qin, Yangzhong

A Caspase-1-cathepsin AND-Gate Probe for Selective Imaging of Inflammasome Activation 一种Caspase-1-组织蛋白酶AND门探针，用于选择性成像炎症小体激活

ACS CHEMICAL BIOLOGY

IF3.8

2025-09-01

PREAI

Chen, Shiyu; Goncin, Una; Zhu, Jiyun; Su, Shih-Po; Czyzyk, Traci Ann; Miller, Corin O.; Sadabad, Raana Kashfi; Bogyo, Matthew

Low Intrinsic Killing Activity and no Impact of Its Positivity on Phase 3 Pneumococcal Vaccine Adult Studies 低固有杀灭活性及其阳性对三期肺炎球菌疫苗成人研究无影响

JOURNAL OF INFECTIOUS DISEASES

IF4.5

2025-09-01

PREAI

Xu, Weifeng; Antonello, Joseph; Nguyen, Jennifer; Ma, Chuying; Cheng, Ya-Wen; Marullo, Kasia; Nolan, Katrina; Buchwald, Ulrike K.; Platt, Heather L.; Bonhomme, Marie; LaFon, David C.; Burton, Robert L.; Nahm, Moon H.; Helmy, Roy

Promoting Secretion of Pathological Tau Species Using an Induced Proximity Platform That Engages the Autophagy Pathway 通过诱导邻近平台促进病理性Tau物种分泌，该平台激活了自噬通路

ACS CHEMICAL NEUROSCIENCE

IF3.9

2025-05-09

PREAI

Kovalyova, Yekaterina; De Leon, Cesar; Krasowska-Zoladek, Alicja; Suon, Sokreine; Wong, Jacky; Young, Seth; Heberling, Julien Lee; Price, Laura; Berger, Raphae''lle; Magliaro, Brian; Cheng, Yu-Shan; Peier, Andrea; Rothman, Deborah M.; Walji, Abbas; Smith, Sean; Marcus, Jacob; Han, Xiaoqing; Usenovic, Marija

Implementation of multimodal anion exchange chromatography to address product quality challenges and downstream platform limitations: A case study

JOURNAL OF CHROMATOGRAPHY A

IF4

2025-04-01

PREAI

Robinson, Julie; Vats, Mayank; Hartmann, Michael