未登录 Generation and characterization of induced pluripotent stem cell (iPSC) lines from patients affected with Tay-Sachs and Sandhoff disease 从患有Tay-Sachs病和Sandhoff病的患者中诱导多能干细胞（iPSC）系的产生与表征 Jovanovic, Vukasin M.; Chen, Catherine Z.; Toro, Camilo; Hurd, Kerstin A.; Zou, Jizhong; Tifft, Cynthia J.; Zheng, Wei; Henderson, Mark J.; Marugan, Juan; Tristan, Carlos A. 分享 收藏
Development of Scalable and Commercial Synthesis for GS-441524 GS-441524的可扩展及商业化合成开发 Gajula, Praveen; Vasilev, Maksim; Li, Jiezhen; Gangu, Aravind S.; Lee, Daniel; Tung, Hsien-Hsin; Mamunooru, Manasa; Wang, Zhirui; Chen, Anji; Rana, Jagruti; Yin, Jinya; Regati, Sridhar; Karmakar, Anupam; Ghosh, Angshuman; Chatterjee, Subhadeep; Yadaw, Ajay K.; Roy, Subho; Bandu, Raju; Dissanayake, Kumuduni; Bietsch, Jonathan; Wannere, Chaitanya; Krishnamurthy, Dhileepkumar; Sirasani, Gopal; Achanta, Srinivas; Armstrong III, Joseph D.; Huang, Junfeng; Sanderson, Philip E.; Qu, Bo; Senanayake, Chris H. 分享 收藏
Integrating qHTS and QSAR Models to Identify Safe GPCR-Targeted Compounds: A Focus on hERG-Dependent Cardiotoxicity 整合qHTS和QSAR模型以识别安全的GPCR靶向化合物：聚焦hERG依赖性心脏毒性 Luo, Xi; Zhao, Jinghua; Sakamuru, Srilatha; Xia, Menghang; Xu, Tuan; Travers, Jameson; Klumpp-Thomas, Carleen; Zhu, Hu; Hall, Matthew D.; Ferguson, Stephen S.; Reif, David M.; Huang, Ruili 分享 收藏
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CURE ID: A Platform to Collect Real-World Treatment Data for Drug Repurposing in Rare Genetic Disorders Farid, Tahsin; Ruzhnikov, Maura R. Z.; Duggal, Mili; Tumas, Keyla C.; Strongin, Shira; Sid, Eric; Fuchs, Sarah R.; Sacks, Leonard; Pichard, Dominique C.; Pilgrim-Grayson, Catherine; Mathe, Ewy A.; Stone, Heather A. 分享 收藏
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Investigating the HIV epidemic among Black gay and bisexual men in the Southern United States: Results of the HPTN 096 pilot cross-sectional assessment 调查美国南部黑人男男同性恋和双性恋人群中的艾滋病流行情况：HPTN 096试点横断面评估的结果 Beyrer, Chris; Remien, Robert H.; Eshleman, Susan H.; Gamble, Theresa R.; De Dieu Tapsoba, Jean; Labbett, Rita L.; Sullivan, Philip A.; Laeyendecker, Oliver; Anderson, Peter L.; Agravat, Devang; Hughes, James P.; Driffin, Daniel D.; Hutchinson, Craig S.; Hucks-Ortiz, Christopher; Adair, Maurice; Curry, Melissa; Jones, Shakita Brooks; Haddock, Ian L.; Boyd, Donte; Burwen, Dale R.; Johnson, Anna Satcher; Nelson, LaRon E. 分享 收藏
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A global survey about undiagnosed rare diseases: perspectives, challenges, and solutions Baldovino, Simone; Sciascia, Savino; Carta, Claudio; Salvatore, Marco; Cellai, Laura L.; Ferrari, Gianluca; Lumaka, Aime; Groft, Stephen; Alanay, Yasemin; Azam, Maleeha; Baynam, Gareth; Cederroth, Helene; la Paz, Eva Maria Cutiongco-de; Dissanayake, Vajira Harshadeva Weerabaddana; Giugliani, Roberto; Gonzaga-Jauregui, Claudia; Hettiarachchi, Dineshani; Kvlividze, Oleg; Landoure, Guida; Makay, Prince; Melegh, Bela; Ozbek, Ugur; Pagava, Karaman; Puri, Ratna Dua; Romero, Vaness I.; Scaria, Vinod; Jamuar, Saumya S.; Shotelersuk, Vorasuk; Roccatello, Dario; Gahl, William A.; Wiafe, Samuel A.; Bodamer, Olaf; Posada, Manuel; Taruscio, Domenica 分享 收藏
Lessons learned from evaluating defined chemical mixtures in a high-throughput estrogen receptor assay system Parham, Fred; Eccles, Kristin M.; Rider, Cynthia, V; Sakamuru, Srilatha; Xia, Menghang; Huang, Ruili; Tice, Raymond R.; Dinse, Gregg E.; Devito, Michael J. 分享 收藏
Borrelial phosphomannose isomerase as a cell surface localized protein that retains enzymatic activity and promotes host-pathogen interaction Dutta, Shraboni; Rana, Vipin S.; Backstedt, Brian T.; Shakya, Anil K.; Kitsou, Chrysoula; Yas, Ozlem B.; Smith, Alexis A.; Ronzetti, Michael H.; Lipman, Rachel M.; Araujo-Aris, Sarai; Yang, Xiuli; Rai, Ganesha; Lin, Yi-Pin; Herzberg, Osnat; Pal, Utpal 分享 收藏
Active- and Allosteric-Site Cyclic Peptide Inhibitors of Secreted M. tuberculosis Chorismate Mutase van Neer, Renier H. P.; Dranchak, Patricia K.; Aitha, Mahesh; Liu, Lijun; Carlson, Emma K.; Jacobsen, Isabella E.; Battaile, Kevin; Fang, Yuhong; Tao, Dingyin; Rai, Ganesha; Padia, Janak; Lovell, Scott; Suga, Hiroaki; Inglese, James 分享 收藏
Genetic Variants of GBP4: Reduced Risks for Drug-Induced Acute Liver Failure in Non-Finnish European Population GBP4的遗传变异: 降低非芬兰欧洲人群药物诱导的急性肝衰竭的风险 Liao, Tsung-Jen; Xia, Menghang; Hayashi, Paul; Pan, Bohun; Aithal, Guruprasad P.; Lucena, M. Isabel; Andrade, Raul J.; Rule, Jody A.; Lee, William M.; Rakela, Jorge; Huang, Ruili; Chen, Minjun 分享 收藏
Repurposing of lonafarnib as a treatment for SARS-CoV-2 infection Khan, Mohsin; Irvin, Parker; Park, Seung Bum; Ivester, Hannah M.; Ricardo-Lax, Inna; Leek, Madeleine; Grieshaber, Ailis; Jang, Eun Sun; Coutermarsh-Ott, Sheryl; Zhang, Qi; Maio, Nunziata; Jiang, Jian-Kang; Li, Bing; Huang, Wenwei; Wang, Amy Q.; Xu, Xin; Hu, Zongyi; Zheng, Wei; Ye, Yihong; Rouault, Tracey; Rice, Charles; Allen, Irving C.; Liang, T. Jake 分享 收藏
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Multi- Component, Time- Course screening to develop combination cancer therapies based on synergistic toxicity 多组分，时程筛选，以开发基于协同毒性的联合癌症疗法 Ceribelli, Michele; Tosto, Frances Anne; Zhang, Xiaohu; Melani, Christopher J.; Roschewski, Mark; Beck, Erin; Thomas, Carleen Klumpp -; Peer, Cody J.; Wilson, Kelli M.; Chen, Lu; Mcknight, Crystal; Michael, Sam; Itkin, Zina; Shinn, Paul; Figg Sr, William D.; Wilson, Wyndham H.; Staudt, Louis M.; Thomas, Craig J. 分享 收藏
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The state-of-the-art of N-of-1 therapies and the IRDiRC N-of-1 development roadmap Jonker, Anneliene H.; Tataru, Elena-Alexandra; Graessner, Holm; Dimmock, David; Jaffe, Adam; Baynam, Gareth; Davies, James; Mitkus, Shruti; Iliach, Oxana; Horgan, Rich; Augustine, Erika F.; Bateman-House, Alison; Pasmooij, Anna Maria Gerdina; Yu, Tim; Synofzik, Matthis; Douville, Julie; Lapteva, Larissa; Brooks, Philip John; O'Connor, Daniel; Aartsma-Rus, Annemieke 分享 收藏
Discovery of IRAK1/4/pan-FLT3 Kinase Inhibitors as Treatments for Acute Myeloid Leukemia Hoyt, Scott B.; Finocchio, Chris J.; Croll, Elizabeth; Tawa, Gregory J.; Li, Huixu; Ma, Li; Li, Kaikai; Liu, Li; Li, Ranran; Zhang, Xiaohu; Wilson, Kelli; Xu, Xin; Shah, Pranav; Williams, Jordan; Fang, Yuhong; Bolanos, Lyndsey C.; Gracia-Maldonado, Gabriel; Kolt, Amal; Robinson, Christina; Free, Jessica; Edmondson, Elijah F.; Difilippantonio, Simone; Jones, LaQuita M.; Culver-Cochran, Ashley E.; Rosenbaum, Jan S.; Starczynowski, Daniel T.; Thomas, Craig J. 分享 收藏
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