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B

Broad Institute

学者数35
论文数14
被引数0
关联论文 (1725)
发表时间
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Human adult and pediatric multimodal transcriptomic atlas of progression from pressure-loaded to failing right ventricle从压力负荷右心室到衰竭右心室的成人和儿童多模态转录组图谱
errNature Cardiovascular Research
IF10.8
err2026-10-09
err0
errOAAI
errIvan A. Kuznetsov; Kristina Li; Yasmine Guedira; Bridget Simonson; Mark Chaffin; Yonathan T. Aberra; Kenneth C. Bedi; Trace Thome; Yijun Yang; Kirsten Branch; Wencao Zhao; Wenkai Zhu; Wei Zhou; Farid F. Kadyrov; Junedh M. Amrute; Ling Lai; Joanna Griffin; Li Li; Jian Li; Shelley D. Miyamoto; Patrick Ellinor; Kenneth B. Margulies; Kory J. Lavine; Zoltan Arany; Jonathan J. Edwards
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err收藏
35 Targeting HIF2-Driven Endogenous Retroviral Antigens for Immunotherapy in Kidney Cancer35 靶向HIF2驱动的内源性逆转录病毒抗原用于肾癌免疫治疗
errOncologist
IF4.2
err2026-09-02
err0
errOAAI
errQinqin Jiang; Gurcan Gunaydin; Vijyendra Ramesh; Justin Becker; Isabelle Lippincott; Karl Clauser; Sudarsana Addepalli; Jenn Abelin; Steven Carr; Bradley Bernstein; William Freed-Pastor; William Kaelin
err分享
err收藏
Spatial analysis reveals the evolving organization of IDH-mutant glioma空间分析揭示了IDH突变型胶质瘤的演变组织
errCancer Cell
IF44.5
err2026-09-01
err0
errOAAI
errHoefflin, Rouven; Greenwald, Alissa C.; Darnell, Noam Galili; Mount, Christopher W.; Tiomkin, Yali; Castro, L. Nicolas Gonzalez; Wen, Zebin; Simkin, Dor; Patterson, Angelica B.; Goliand, Inna; Golani, Ofra; Fellus-Alyagor, Liat; Cohen, Marina; Joseph, Kevin; Beck, Jurgen; Ravi, Vidhya M.; Kedmi, Merav; Keren-Shaul, Hadas; Weller, Michael; Addadi, Yoseph; Neidert, Marian C.; Suva, Mario L.; Tirosh, Itay
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Physiological basis of contraceptive function of a GSK3α-selective inhibitor, manifested during epididymal sperm maturationGSK3α选择性抑制剂避孕功能在附睾精子成熟过程中表现出的生理学基础
errMolecular Human Reproduction
IF3.5
err2026-08-14
err0
errOAAI
errAditi Khamamkar; Rounak Roy; Dhanu Anneyplar Shivakumar; Neha Choudhari; Rahul Dutta; Michel Weïwer; Satish Kumar Adiga; Srinivasan Vijayaraghavan; Souvik Dey; null
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Plasmodium falciparum HSP90 inhibitors show divergent resistance despite a shared ATP-binding site恶性疟原虫HSP90抑制剂表现出差异性耐药性，尽管具有共同的ATP结合位点
errCell Reports
IF6.9
err2026-07-01
err0
errOAAI
errKo, Fu-Hsuan; Lukens, Amanda K.; de Souza, Mariana Laureano; Foy, Alex; Hsiao, Jason; Ndiaye, Tolla; Okombo, John; Yeo, Tomas; Park, Heekuk; Uhlemann, Anne-Catrin; Boonyalai, Nonlawat; Kumpornsin, Krittikorn; Girling, Gareth; Pasaje, Charisse; Godoy, Luiz; Kapoor, Priyan; Durst, Gregory L.; Ottilie, Sabine; Chatterjee, Arnab; Niles, Jacquin; Lee, Marcus; Fidock, David A.; Wirth, Dyann F.; Winzeler, Elizabeth A.
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Prioritizing Discovery and Advancements in Arrhythmia Therapies NIH/NHLBI Workshop优先考虑心律失常治疗领域的发现与进展：NIH/NHLBI研讨会
errJACC-Clinical Electrophysiology
IF7.7
err2026-06-01
err0
PREAI
errHanna, Peter; Boyle, Patrick M.; Caldwell, Jessica L.; El Refaey, Mona; Goodyer, William R.; Khurshid, Shaan; Mesubi, Olurotimi O.; Palatinus, Joseph A.; Pfenniger, Anna; Ajijola, Olujimi A.; Albert, Christine M.; Armoundas, Antonis A.; Benjamin, Emelia J.; Clancy, Colleen E.; Al-Khatib, Sana M.; Bilchick, Kenneth; Delmar, Mario; Donahue, J. Kevin; Fishman, Glenn I.; Goldenberg, Ilan; Gourdie, Robert G.; Huang, David T.; Knollmann, Bjorn C.; Ko, Darae; Lubitz, Steven A.; Marchlinski, Francis E.; Marston, Nicholas A.; Moskowitz, Ivan P.; Noseworthy, Peter A.; Prather, Randall S.; Radwanski, Przemyslaw B.; Rajamani, Sridharan; Rentschler, Stacey; Roden, Dan M.; Russo, Andrea; Saffitz, Jeffrey E.; Sotoodehnia, Nona; Webster, Gregory; Wu, Sean M.; Adhikari, Bishow B.; Bandettini, W. Patricia; Desvigne-Nickens, Patrice; Shanbhag, Sujata M.; Schopfer, David; Sopko, George; Tjurmina, Olga A.; Balijepalli, Ravi C.; McNally, Elizabeth; Shivkumar, Kalyanam
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Ergosterol-depleted clinical isolates of Nakaseomyces glabratus can develop multi-drug resistance without severe fitness defects or attenuated virulence in an invertebrate infection model胶红酵母临床分离株中缺乏麦角甾醇可发展出多药耐药性，而未在无脊椎动物感染模型中引起严重的适应性缺陷或毒力减弱
errmBio
IF4.7
err2026-05-01
err0
PREAI
errAldejohann, Alexander M.; Thielemann, Nadja; Martinez Zurita, Aina; Muller, Christoph; Grafenhan, Tom; Kriz, Richard; Lagler, Heimo; Behr, Isabell S.; Reus, Nathalie; Schoninger, Annika; Walther, Grit; Mazan, Lena-Marie; Wilhelm, Hannah; Willinger, Birgit; Cuomo, Christina A.; Kurzai, Oliver; Martin, Ronny
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err收藏
A genetic platform to deconvolve efficacy and toxicity reveals the on-target effects of CDK11 inhibition in vivo一个用于解析功效和毒性的遗传平台揭示了CDK11抑制在体内的靶向效应
errNature Communications
IF15.7
err2026-01-01
err0
errOAAI
errLinda Julian; Lisa Crozier; Devon A. Lukow; Aditi Swamy; Sanat Mishra; Ryan A. Hagenson; Peter C. Sennhenn; Erin L. Sausville; Amy J. S. McGeoch; Sarah L. Thompson; Brianna E. Mendelson; Claudio E. Chuaqui; Lu Qiao; Anand Vasudevan; Kuan-Ting Lin; Sonam Bhatia; Thierry Bertomeu; Andrew Chatr‐aryamontri; Li Zhang; Matthew G. Rees; Melissa M. Ronan; Jennifer A. Roth; Timothy Nottoli; Suxia Bai; Jayalakshmi Lakshmipathi; Viswanathan Muthusamy; Jonathan G. Van Vranken; Gregory Gauthier-Coles; Steven P. Gygi; Joan C. Smith; Kendall L. Anderson; Sanjana Shah; Ranjit S. Bindra; Martin Akerman; David L. Spector; Basil J. Greber; Adrian R. Krainer; Jason M. Sheltzer
err分享
err收藏
Machine learning–assisted directed evolution of plant Rubisco机器学习辅助的植物Rubisco定向进化
errScience Advances
IF12.5
err2026-01-01
err0
PREAI
errJulie L. McDonald; Jiacheng Lin; Yunlong Zhao; Brian Hie; Rosemary J. Birch; Mary A. Gehring; Bryan D. Bryson; Spencer Michael Whitney; Matthew D. Shoulders; Robert H. Wilson
err分享
err收藏
Identification of prediagnostic proteomic biomarkers for colon and rectal cancer in 3 prospective cohorts在3项前瞻性队列中识别结直肠癌的预诊断蛋白质组学生物标志物
errJNCI: Journal of the National Cancer Institute
IF0
err2026-01-01
err0
errOAAI
errXinyuan Zhang; Jonathan M. Downie; David A. Drew; Keming Yang; Suzanne Gaye Orchard; John Raymond Zalcberg; Meir J. Stampfer; Edward L. Giovannucci; Shuji Ogino; Robert Edgardo Gerszten; Jeffrey A. Meyerhardt; Erica T. Warner; Robyn L. Woods; Rory Wolfe; Peter Gibbs; Mingyang Song; Yin Cao; Andrew T. Chan
err分享
err收藏
Antisense Oligonucleotides that Are Toxic to Prion-Infected Mice Share an Emergent Mechanism反义寡核苷酸对朊病毒感染小鼠具有毒性并共享一种涌现机制
errNucleic Acid Therapeutics
IF4.7
err2026-01-01
err0
PREAI
errHien T. Zhao; Jill O’Moore; Daniel A. Sprague; Juliana E Gentile; Sagar S. Damle; Briana Noble; Taylor L Corridon; Simone Lord; Jason Le; Samantha Graffam; Michael Howard; Kendrick DeSouza-Lenz; Hongda Li; John E. Matson; Susan Li; Stéphanie Klein; Tyler J. Caron; Alissa A. Coffey; Sonia M. Vallabh; Holly B. Kordasiewicz; Andrea Grindeland Panter; Eric Vallabh Minikel
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err收藏
Human trilayer engineered blood vessel reveals influence of fibroblasts on disease progression in model of Hutchinson-Gilford progeria人源三层工程化血管揭示成纤维细胞对哈钦森-吉尔福德早衰症模型疾病进展的影响
errScience Advances
IF12.5
err2026-01-01
err0
PREAI
errKevin L. Shores; Xin D. Gao; David R. Liu; George A. Truskey
err分享
err收藏
Distinct Genetic Risk Profile in Aortic Stenosis Compared With Coronary Artery Disease与冠状动脉疾病相比，主动脉瓣狭窄的遗传风险特征不同
errJAMA CARDIOLOGY
IF14.1
err2025-02-01
err1
PREAI
errTrenkwalder, Teresa; Maj, Carlo; Al-Kassou, Baravan; Debiec, Radoslaw; Doppler, Stefanie A.; Musameh, Muntaser D.; Nelson, Christopher P.; Dasmeh, Pouria; Grover, Sandeep; Knoll, Katharina; Naamanka, Joonas; Mordi, Ify R.; Braund, Peter S.; Dressen, Martina; Lahm, Harald; Wirth, Felix; Baldus, Stephan; Kelm, Malte; von Scheidt, Moritz; Krefting, Johannes; Ellinghaus, David; Small, Aeron M.; Peloso, Gina M.; Natarajan, Pradeep; Thanassoulis, George; Engert, James C.; Dufresne, Line; Franke, Andre; Goerg, Siegfried; Laudes, Matthias; Nowak-Goettl, Ulrike; Vaht, Mariliis; Metspalu, Andres; Stoll, Monika; Berger, Klaus; Pellegrini, Costanza; Kastrati, Adnan; Hengstenberg, Christian; Lang, Chim C.; Kessler, Thorsten; Hovatta, Iiris; Nickenig, Georg; Noethen, Markus M.; Krane, Markus; Schunkert, Heribert; Samani, Nilesh J.; Schumacher, Johannes
err分享
err收藏
A Kinetic Scout Approach Accelerates Targeted Protein Degrader Development
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2024-12-16
err0
errOAAI
errFan, Angela T.; Gadbois, Gillian E.; Huang, Hai-Tsang; Chaudhry, Charu; Jiang, Jiewei; Sigua, Logan H.; Smith, Emily R.; Wu, Sitong; Poirier, Grace J.; Dunne-Dombrink, Kara; Goyal, Pavitra; Tao, Andrew J.; Sellers, William R.; Fischer, Eric S.; Donovan, Katherine A.; Ferguson, Fleur M.
err分享
err收藏
Deeper evaluation of a single-cell foundation model单细胞基础模型的更深入评估
errNATURE MACHINE INTELLIGENCE
IF23.9
err2024-12-12
err1
PREAI
errBoiarsky, Rebecca; Singh, Nalini M.; Buendia, Alejandro; Amini, Ava P.; Getz, Gad; Sontag, David
err分享
err收藏
Cell Painting: a decade of discovery and innovation in cellular imaging (Dec, 10.1038/s41592-024-02528-8, 2024)
errNATURE METHODS
IF32.1
err2024-12-12
err0
PREAI
errSeal, Srijit; Trapotsi, Maria-Anna; Spjuth, Ola; Singh, Shantanu; Carreras-Puigvert, Jordi; Greene, Nigel; Bender, Andreas; Carpenter, Anne E.
err分享
err收藏
QClus: a droplet filtering algorithm for enhanced snRNA-seq data quality in challenging samples
errNUCLEIC ACIDS RESEARCH
IF13.1
err2024-12-05
err0
errOAAI
errSchmauch, Eloi; Ojanen, Johannes; Galani, Kyriakitsa; Jalkanen, Juho; Harju, Kristiina; Hollmen, Maija; Kokki, Hannu; Gunn, Jarmo; Halonen, Jari; Hartikainen, Juha; Kiviniemi, Tuomas; Tavi, Pasi; Kaikkonen, Minna U.; Kellis, Manolis; Linna-Kuosmanen, Suvi
err分享
err收藏
Cell Painting: a decade of discovery and innovation in cellular imaging细胞绘画: 细胞成像的十年发现和创新
errNATURE METHODS
IF32.1
err2024-12-05
err1
PREAI
errSeal, Srijit; Trapotsi, Maria-Anna; Spjuth, Ola; Singh, Shantanu; Carreras-Puigvert, Jordi; Greene, Nigel; Bender, Andreas; Carpenter, Anne E.
err分享
err收藏
X-linked deletion of Crossfirre, Firre, and Dxz4 in vivo uncovers diverse phenotypes and combinatorial effects on autosomes
errNATURE COMMUNICATIONS
IF15.7
err2024-12-05
err0
errOAAI
errHasenbein, Tim P.; Hoelzl, Sarah; Smith, Zachary D.; Gerhardinger, Chiara; Gonner, Marion O. C.; Aguilar-Pimentel, Antonio; Amarie, Oana V.; Becker, Lore; Calzada-Wack, Julia; Dragano, Nathalia R. V.; da Silva-Buttkus, Patricia; Garrett, Lillian; Hoelter, Sabine M.; Kraiger, Markus; Oestereicher, Manuela A.; Rathkolb, Birgit; Sanz-Moreno, Adrian; Spielmann, Nadine; Wurst, Wolfgang; Gailus-Durner, Valerie; Fuchs, Helmut; de Angelis, Martin Hrabe; Meissner, Alexander; Engelhardt, Stefan; Rinn, John L.; Andergassen, Daniel
err分享
err收藏
Safer and efficient base editing and prime editing via ribonucleoproteins delivered through optimized lipid-nanoparticle formulations
errNATURE BIOMEDICAL ENGINEERING
IF26.6
err2024-11-28
err0
errOAAI
errHolubowicz, Rafal; Du, Samuel W.; Felgner, Jiin; Smidak, Roman; Choi, Elliot H.; Palczewska, Grazyna; Menezes, Carolline Rodrigues; Dong, Zhiqian; Gao, Fangyuan; Medani, Omar; Yan, Alexander L.; Holubowicz, Maria W.; Chen, Paul Z.; Bassetto, Marco; Risaliti, Eleonora; Salom, David; Workman, J. Noah; Kiser, Philip D.; Foik, Andrzej T.; Lyon, David C.; Newby, Gregory A.; Liu, David R.; Felgner, Philip L.; Palczewski, Krzysztof
err分享
err收藏