Glaxosmithkline

学者数637

论文数200

被引数0

关联论文 (198)

发表时间

MALT1 protease inhibition restrains glioblastoma progression by reversing tumor-associated macrophage-dependent immunosuppression in mice MALT1蛋白酶抑制通过逆转肿瘤相关巨噬细胞依赖的免疫抑制抑制胶质母细胞瘤进展（在小鼠中）

Nature Communications

IF15.7

2026-08-10

OAAI

Juliana Hofstätter Azambuja; Saigopalakrishna S. Yerneni; Lisa M. Maurer; Hannah E. Crentsil; Gabriela N. Debom; Linda Klei; Mei Smyers; Chaim T. Sneiderman; Kristina E. Schwab; Rajesh Acharya; Aivi T. Nguyen; Josie L. Emery; John W. Little; Jeffrey A. Meridew; Yijen Lin Wu; Prasanna Ekambaram; Dong Hu; Pete J. Gough; John Bertin; Ari Melnick; Gary Kohanbash; Riyue Bao; Peter C. Lucas; Linda M. McAllister-Lucas

Alternative approaches to phase III clinical trials for vaccine efficacy and licensure: the role of real-world evidence - a meeting report 疫苗效力和许可的III期临床试验替代方案：真实世界证据的作用——会议报告

Biologicals

IF1.5

2026-08-01

OAAI

de Moerlooze, Laurence; Allen, Alexander; Bartalesi, Ilaria; Cavaleri, Marco; Davenport, Miles P.; Gessner, Bradford D.; Gomes, Brenda; Hayford, Kyla; Izu, Alane; Izurieta, Hector S.; Jenkins, Victoria A.; Kastner, Randee; Krause, Phil; Nealon, Joshua; Oostvogels, Lidia; Palmu, Arto A.; Read, Robert C.; Saenz, Carla; Smith, Dean K.; Tuboi, Suely; Vandendriessche, Frank; Baay, Marc; Craig, Danielle; Neels, Pieter; Bollaert, Kaatje

Immune aging biomarkers for clinical trials 用于临床试验的免疫衰老生物标志物

Nature Medicine

IF50

2026-07-03

PREAI

Andrea Cipriano; Jamie Justice; Jesse R. Poganik; Mahdi Moqri; Omar O. Abudayyeh; Jonathan Gootenberg; Laura Haynes; Yotam Levin; Daniel E. Martin-Herranz; Arne N. Akbar; Joan Mannick; Graham Pawelec; Shai S. Shen-Orr; John Tsang; Wolfgang Wagner; Miriam Merad; Sacha Gnjatic; Alfred Gellhorn; Michael J. Corley; George A. Kuchel; Luigi Ferrucci; David Furman; Chiara M. S. Herzog

The Human Chk1 Inhibitor CHIR-124 Shows Multistage Activity against the Human Malaria Parasite Plasmodium falciparum via Polypharmacological Inhibition of PfArk1 and Hemozoin Formation 人源Chk1抑制剂CHIR-124通过多药理抑制作用抑制PfArk1和血红素结晶形成，对人疟原虫恶性疟原虫表现出多阶段活性

ACS Chemical Biology

IF3.8

2026-06-13

OAAI

Kathryn J. Wicht; John G. Woodland; Larnelle F. Garnie; Henrico Langeveld; Dale Taylor; Luiz C. Godoy; Charisse Flerida A. Pasaje; Mariana Laureano de Souza; Jair L. Siqueira-Neto; Sonja Ghidelli-Disse; Maria Jose Lafuente-Monasterio; Francisco-Javier Gamo; Dina Coertzen; Janette Reader; Mariëtte van der Watt; Jessica L. Bridgford; Gareth Girling; Rachael Coyle; Christian Scheurer; Sergio Wittlin; Arne Alder; Tim-Wolf Gilberger; Marcus C. S. Lee; Till S. Voss; Elizabeth A. Winzeler; David A. Fidock; Jacquin C. Niles; Lyn-Marié Birkholtz; Lauren B. Coulson; Kelly Chibale

Cell-type-resolved genetic variation shapes inflammatory bowel disease risk 细胞类型分辨的遗传变异塑造炎症性肠病风险

Nature

IF48.5

2026-06-03

OAAI

Tobi Alegbe; Bradley T. Harris; Laura Fachal; Lucia Ramirez-Navarro; Marcus Tutert; Monika Krzak; Mennatallah Ghouraba; Michelle Strickland; Matiss Ozols; Celeste E. Cohen; Saniya Khullar; Eleonora Khabirova; Nikolaos I. Panousis; David Ochoa; Noor Wana; May Xueqi Hu; Jason Skelton; Jasmin Ostermayer; Kimberly Ai Xian Cheam; D. Leland Taylor; Yong Gu; Claire Dawson; Tina Thompson; Kenneth Arestang; Nilanga Nishad; Biljana Brezina; Charry Queen Caballes; Wendy Garri; Steven Leonard; Vivek Iyer; Miles Parkes; Chris Wallace; Rebecca E. McIntyre; Cristina Cotobal Martin; Gareth-Rhys Jones; Tim Raine; Carl A. Anderson

The double-edged nature of antibody bivalency: mathematical and experimental analysis of cell surface antigen occupancy and opsonization 抗体双价性的双重性质：细胞表面抗原占据和调理作用的数学与实验分析

mAbs

IF7.3

2026-06-03

OAAI

Luke Heirene; James Lodge; Marina Fedorova; Ross Gauntlett; Joanna Cordy; Zahra Rattray; Helen Byrne; Eamonn Gaffney; James W. T. Yates

The emerging use of artificial intelligence in safety pharmacology and toxicology 人工智能在安全药理学和毒理学中的新兴应用

Journal of Pharmacological and Toxicological Methods

IF1.8

2026-06-01

PREAI

Miller, Lutfiya; Treleaven, Ian; El Amrani, Abdel-Ilah; Rossman, Eric I.; Winters, Brett R.; Pugsley, Michael K.

Safety and Effectiveness of Intravenous Belimumab in Patients with Systemic Lupus Erythematosus in South Korea: A Multicentre, Observational, Real-World Study 韩国系统性红斑狼疮患者中静脉注射贝利木单抗的安全性与有效性：一项多中心、观察性、真实世界研究

DRUGS-REAL WORLD OUTCOMES

IF1.9

2026-06-01

OAAI

Yoo, Sang-Bae; Cho, Jung-Eun; Baek, Da-Jung; Lee, Eun-Bin; Park, Sung-Hwan; Kim, Sang-Hyon; Lee, Eun Young; Lee, Yeon-Ah; Bae, Sang-Cheol

Pain and frailty progression in adult survivors of childhood cancer: a report from the St Jude Lifetime Cohort study 成年儿童癌症幸存者的疼痛和虚弱进展：St Jude Lifetime队列研究报道

The Lancet Healthy Longevity

IF0

2026-05-28

OAAI

Cassie M Argenbright; Chiara Papini; Zhenghong Li; Matthew J Ehrhardt; Angela Delaney; Robyn E Partin; Deokumar Srivastava; Melissa M Hudson; Kirsten K Ness; Tara M Brinkman

Estimating respiratory syncytial virus health utility values for older adults and their caregivers in the Japanese population: a time trade-off study 估算日本老年人群及其照护者中呼吸道合胞病毒健康效用值：一项时间权衡研究

Expert Review of Pharmacoeconomics & Outcomes Research

IF1.5

2026-05-28

OAAI

Rendas-Baum, Regina; Bjorner, Jakob; Preckler, Victor; Matsuki, Taizo; Ho, Yufan; Molnar, Daniel; Noto, Shinichi; Igarashi, Ataru

Rethinking Immunity in Tissues: The Biology of Tertiary Lymphoid Structures 重新思考组织中的免疫：三级淋巴样结构的生物学

Immunological Reviews

IF8.3

2026-05-27

OAAI

Michelle A. Linterman; Palwinder K. Mander

Analysis of nitrite in pharmaceutical excipients: A multi-laboratory comparative study 分析药品辅料中硝酸盐的方法：一项多实验室比较研究

European Journal of Pharmaceutical Sciences

IF4.7

2026-05-23

OAAI

Blom, Giorgio; Balogh, Tamas; Loos, Petra; Zheng, Jinjian; Kocks, Grace; Packer, Gemma

Costs of managing adverse reactions to hexavalent vaccines: Comparison of DT3aP-HBV-IPV/Hib and DT2aP-HBV-IPV-Hib in France and Spain 管理六价疫苗不良反应的成本：法国和西班牙DT3aP-HBV-IPV/Hib与DT2aP-HBV-IPV-Hib的比较

Human Vaccines & Immunotherapeutics

IF0

2026-05-23

PREAI

Nikitas, George; Mohy, Ahmed; Duchenne, Maurine; Genovez, Victoria; Casabona, Giacomo; Hennessy, Elizabeth; Vallejo, Laura; Haddouche, Abdallah Aylan; Marijam, Alen

Cost-effectiveness of a single dose of the adjuvanted RSVPreF3 vaccine for the prevention of respiratory syncytial virus (RSV) among patients with chronic obstructive pulmonary disease in Italy

Expert Review of Vaccines

IF4.8

2026-05-23

OAAI

Puggina, Anna; Rumi, Filippo; Zarkadoulas, Eleftherios; Lorenzini, Giancarlo; Di Marco, Fabiano; Calabro, Giovanna Elisa

The real-world economic impact of herpes zoster disease in patients with selected underlying conditions in Spain 西班牙特定基础疾病患者带状疱疹疾病的经济影响

Human Vaccines & Immunotherapeutics

IF0

2026-05-23

OAAI

Moza Morinigo, Helena; Garcia, Andrea; Zarkadoulas, Eleftherios; Cambronero Martinez, Maria Del Rosario; Varas, Javier; Martin, Alba; Garcia, Maria; Trento, Alfonsina; Hernandez, Ignacio; Vallejo-Aparicio, Laura Amanda

Vaccines as Global Health Security Infrastructure: Insights from a Descriptive Analysis of Vaccines Europe Members’ Clinical Pipelines 疫苗作为全球卫生安全基础设施：欧洲疫苗成员临床试验管线描述性分析的见解

Vaccines

IF3.4

2026-05-20

OAAI

Charlotte Vernhes; Kateryna Khmilevska; Alexis Caron; Emanuele Ciglia; Rosybel Drury; Judith Perez-Gomez; Volker Vetter

Developing and assessing acceptability of a shared decision-making tool for selecting among HIV pre-exposure prophylaxis options in the United States of America 开发和评估在美国选择艾滋病病毒暴露前预防方案的共享决策工具的可接受性

PLOS Global Public Health

IF2.5

2026-05-19

OAAI

Davis, Wendy W.; Mantsios, Andrea; Metzner, Aimee A.; Talan, Ali; Kwait, Jennafer; Rodriguez, Humberto Gonzalez; Karver, Tahilin Sanchez; Wilhite, Daniel; Barker, Suyanna; Suarez, Angela; Fernandez, Ricardo; Rodriguez-Diaz, Carlos E.; Taggart, Tamara; Oglesby, Alan; Wohl, David; Barrington, Clare; Kerrigan, Deanna

Population Pharmacokinetic Modeling of Niraparib to Assess Different Absorption Models 尼拉帕尼群体药代动力学建模以评估不同的吸收模型

Journal of Clinical Pharmacology

IF2.3

2026-05-19

OAAI

Gaffney, Anna; Franchetti, Yoko; Desrosiers, Mathieu; Trame, Mirjam N.; Jewell, Roxanne C.

Approaches to observational study designs and analytical options to evaluate the safety of multi-dose vaccines: a systematic review 观察性研究设计方案和评估多剂量疫苗安全性的分析选择：一项系统综述

Expert Review of Vaccines

IF4.8

2026-05-18

OAAI

Monica Mtei; Tu Pham Hien Trang; Adoración Navarro-Torné; Ian J. Douglas; Anna Schultze

Transportability Analyses in Comparative Effectiveness Research: A Conceptual Framework and Methodological Principles Endorsed by the International Society for Pharmacoepidemiology 比较疗效研究中的可推广性分析：国际药物流行病学学会认可的概念框架和方法学原则

Pharmacoepidemiology and Drug Safety

IF2.4

2026-05-17

OAAI

Adamson, Blythe; Liu, Wei; Duffield, Stephen; Deruaz-Luyet, Anouk; Bennett, Dimitri; Gabarro, Montse Soriano; Burcu, Mehmet; Moga, Daniela Claudia; Welby, Sarah; Jiao, Tianze; Wen, Xuerong; Sarri, Grammati