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L

Laralynne Przybyla

denali therapeutics
H指数:18
被引数:3,071

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LASER couples damage sensing to ESCRT assembly for lysosome repair

激光将损伤感知与ESCRT组装耦合以用于溶酶体修复

Nature
IF48.5
2026-06-030
OAAI
Claire S. Goul; Aakriti Jain; Samira Yitiz; Zahra E. Soltani; Serim Yang; Simon Rapp; Martina Spacci; Scot Federman; James Sacco; Huinan Li; Lauren D. Enriquez; Nalan Liv; Laralynne Przybyla; Roberto Zoncu
Network-aware self-supervised learning enables high-content phenotypic screening for genetic modifiers of neuronal activity dynamics

网络感知的自我监督学习可以对神经元活动动力学的遗传修饰进行高含量的表型筛选

Nature Machine Intelligence
IF23.9
2025-12-170
PRE
Parker Grosjean; Kaivalya Shevade; Cuong Nguyen; Sarah Ancheta; Karl Mader; Ivan Franco; Seok-Jin Heo; Greyson Lewis; Dehua Zhao; Bhairavi Tolani; Steven Boggess; Angelique Di Domenico; Erik Ullian; Shawn Shafer; Adam Litterman; Laralynne Przybyla; Michael J. Keiser; Jamie Ifkovits; Adam Yala; Martin Kampmann
Simultaneous capture of single cell RNA-seq, ATAC-seq, and CRISPR perturbation enables multiomic screens to identify gene regulatory relationships

同时捕获单细胞RNA测序、ATAC-seq和CRISPR扰动，能够实现多组学筛选以识别基因调控关系

Cell Reports Methods
IF4.5
2025-11-100
OAAI
Kaivalya Shevade; Yeqing Angela Yang; Kevin Feng; Karl Mader; Volkan Sevim; Jacob Parsons; Gunisha Arora; Hasnaa Elfawy; Rachel Mace; Scot Federman; Rustam Esanov; Shawn Shafer; Eric D. Chow; Laralynne Przybyla
TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge

TREM2在慢性吞噬细胞攻击后调节小胶质细胞胆固醇代谢

NEURON
IF15
2020-03-01408
OAAI
Nugent, Alicia A.; Lin, Karin; van Lengerich, Bettina; Lianoglou, Steve; Przybyla, Laralynne; Davis, Sonnet S.; Llapashtica, Ceyda; Wang, Junhua; Kim, Do Jin; Xia, Dan; Lucas, Anthony; Baskaran, Sulochanadevi; Haddick, Patrick C. G.; Lenser, Melina; Earr, Timothy K.; Shi, Ju; Dugas, Jason C.; Andreone, Benjamin J.; Logan, Todd; Solanoy, Hilda O.; Chen, Hang; Srivastava, Ankita; Poda, Suresh B.; Sanchez, Pascal E.; Watts, Ryan J.; Sandmann, Thomas; Astarita, Giuseppe; Lewcock, Joseph W.; Monroe, Kathryn M.; Di Paolo, Gilbert
A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma
NATURE CELL BIOLOGY
IF19.1
2018-09-10108
OAAI
Barnes, J. Matthew; Kaushik, Shelly; Bainer, Russell O.; Sa, Jason K.; Woods, Elliot C.; Kai, FuiBoon; Przybyla, Laralynne; Lee, Mijeong; Lee, Hye Won; Tung, Jason C.; Maller, Ori; Barrett, Alexander S.; Lu, Kan V.; Lakins, Jonathon N.; Hansen, Kirk C.; Obernier, Kirsten; Alvarez-Buylla, Arturo; Bergers, Gabriele; Phillips, Joanna J.; Nam, Do-Hyun; Bertozzi, Carolyn R.; Weaver, Valerie M.
Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix
MOLECULAR BIOLOGY OF THE CELL
IF2.7
2017-06-01126
OAAI
Mekhdjian, Armen H.; Kai, FuiBoon; Rubashkin, Matthew G.; Prahl, Louis S.; Przybyla, Laralynne M.; McGregor, Alexandra L.; Bell, Emily S.; Barnes, J. Matthew; DuFort, Christopher C.; Ou, Guanqing; Chang, Alice C.; Cassereau, Luke; Tan, Steven J.; Pickup, Michael W.; Lakins, Jonathan N.; Ye, Xin; Davidson, Michael W.; Lammerding, Jan; Odde, David J.; Dunn, Alexander R.; Weaver, Valerie M.

研究方向

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V
Valerie M. Weaver
H 指数:94论文数:443被引数:5.7万
S
Scot Federman
H 指数:35论文数:84被引数:9,979
K
Kaivalya Shevade
H 指数:4论文数:10被引数:168
S
Shawn Shafer
H 指数:4论文数:13被引数:48
J
J. Matthew Barnes
H 指数:18论文数:75被引数:2,442
J
Joel Voldman
H 指数:43论文数:208被引数:7,948
E
Eric D. Chow
H 指数:30论文数:120被引数:9,820
L
Luke A. Gilbert
H 指数:46论文数:216被引数:2.8万
Y
Yeqing Angela Yang
H 指数:18论文数:35被引数:3,372
S
Seok‐Jin Heo
H 指数:16论文数:35被引数:1,553