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L

Luke A. Gilbert

University of California San Francisco
H指数:46
被引数:2.8万

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Genome-scale CRISPR screens identify PTGES3 as a direct modulator of androgen receptor function in advanced prostate cancer

基因组规模CRISPR筛选确定PTGES3为晚期前列腺癌雄激素受体功能的直接调节因子

Nature Genetics
IF29
2025-11-050
OAAI
Haolong Li; James E. Melnyk; Becky Xu Hua Fu; Raunak Shrestha; Meng Zhang; Martin Sjöström; Siyu Feng; Jasmine A. Anderson; Wanting Han; Lisa N. Chesner; Hyun Jin Shin; Tatyanah Farsh; Humberto J. Suarez; Seema Nath; Jonathan Chou; Rajdeep Das; Emily A. Egusa; Marsha Calvert; Audrey Kishishita; Abhilash Barpanda; Jun Zhu; Ashutosh Maheshwari; William S. Chen; Mohammed Alshalalfa; Aidan Winters; Junjie T. Hua; Tianyi Liu; Elai Davicioni; Arun P. Wiita; Bradley A. Stohr; Javed Siddiqui; Bo Huang; Eric J. Small; Kevan M. Shokat; Peter S. Nelson; David A. Quigley; Elizabeth V. Wasmuth; Luke A. Gilbert; Felix Y. Feng
MOLECULAR CHARACTERIZATION OF CRISPROFF EPIGENETIC EDITOR ACTIVITY REVEALS MUTANT ALLELE-SPECIFICTERT REPRESSION IN GLIOBLASTOMA

CRISPR-OFF 表观遗传编辑活性的分子表征揭示了胶质母细胞瘤中突变等位基因特异性的 TERT 抑制

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Hubbard, Akane; Ma, Zerong; Stevers, Nicholas O.; Zou, Christopher; Lin, Katie; Raval, Krish; Sharma, Rohit; Goudy, Laine; Gilbert, Luke A.; Murthy, Niren; Berger, Mitchel S.; Costello, Joseph F.; Liu, S. John
Integrated epigenetic and genetic programming of primary human T cells

整合表观遗传和遗传编程的原代人T细胞

Nature Biotechnology
IF41.7
2025-10-210
OA
Laine Goudy; Alvin Ha; Ashir A. Borah; Jennifer M. Umhoefer; Lauren Chow; Carinna Tran; Aidan Winters; Alexis Talbot; Rosmely Hernandez; Zhongmei Li; Sanjana Subramanya; Abolfazl Arab; Nupura Kale; Jae Hyun J. Lee; Joseph J. Muldoon; Chang Liu; Ralf Schmidt; Philip Santangelo; Julia Carnevale; Justin Eyquem; Brian R. Shy; Alex Marson; Luke A. Gilbert
Exploitable mechanisms of antibody and CAR mediated macrophage cytotoxicity
Nature Communications
IF15.7
2025-07-010
OAAI
Tianyi Liu; Meng Zhang; Tatyanah Farsh; Haolong Li; Audrey Kishishita; Abhilash Barpanda; Stanley G. Leung; Jun Zhu; Hyuncheol Jung; Junjie Tony Hua; Xiaolin Zhu; Alexander B. Kim; Young Ah Goo; Minsoo Son; Jaenyeon Kim; Aish Subramanian; Martin Sjöström; Katherine C. Fuh; Jocelyn S. Chapman; Julia Carnevale; Luke A. Gilbert; Aparna Lakkaraju; Peter M. Bruno; David Quigley; Arun P. Wiita; Felix Y. Feng; Carl J. DeSelm
CDK8 Inhibition Represses Monocyte-like Gene Expression in Acute Myeloid Leukemia Cells and Antagonizes In Vivo Resistance to FLT3 Inhibition

CDK8 抑制在急性髓系白血病细胞中抑制单核细胞样基因表达，并拮抗体内对 FLT3 抑制的抵抗

BLOOD
IF23.1
2024-11-050
PRE
Ferng, Timothy T.; Pintar, Samantha M.; Kennedy, Vanessa E.; Kabir, Shaheen; Tarver, Theodore C., III; Steri, Veronica; Phojanakong, Paul; Hubner, Juwita; Morales, Carolina E.; Rivera, Jose M.; Logan, Aaron C.; Braun, Benjamin; Stieglitz, Elliot; Gilbert, Luke A.; Smith, Catherine C.

研究方向

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J
Jonathan S. Weissman
H 指数:157论文数:561被引数:11.9万
M
Max A. Horlbeck
H 指数:29论文数:99被引数:1.0万
F
Felix Y. Feng
H 指数:109论文数:1,737被引数:5.0万
M
Martin Kampmann
H 指数:57论文数:245被引数:1.5万
D
David A. Quigley
H 指数:40论文数:441被引数:6,016
J
Jacqueline E. Villalta
H 指数:14论文数:50被引数:7,785
H
Hani Goodarzi
H 指数:51论文数:292被引数:1.3万
A
Abolfazl Arab
H 指数:7论文数:40被引数:340
M
Martin Sjöström
H 指数:29论文数:481被引数:3,308
L
Lisa N. Chesner
H 指数:11论文数:56被引数:690