Harris H. Wang - Publications, H-index & Citations

Harris H. Wang

columbia university

53H指数

167论文数

1.5W被引数

收录论文 67

发表时间

Toward life with a 19–amino acid alphabet through generative artificial intelligence design 通过生成式人工智能设计实现包含19种氨基酸字母表的生物合成

Science

IF45.8

2026-04-30

PREAI

Liyuan Liu; Charlotte Rochereau; Simon Kozlov; Guillaume Urtecho; Xiaonan Liu; Jiahui Zhao; Jasmine Wang; Yiming Huang; Yiming Qu; Zetian Zhang; Tomasz Blazejewski; Avi Swartz; Sergey Ovchinnikov; Harris H. Wang

STOOL EXFOLIOME RNA SEQUENCING ENABLES NON-INVASIVE DETECTION OF MUCOSAL DAMAGE IN IBD 粪便脱落基因组RNA测序能够无创检测炎症性肠病中的黏膜损伤

Inflammatory Bowel Diseases

IF4.3

2026-02-01

PREAI

Huang, Yiming; Sun, Yiwei; Giddins, Marla; Wang, Harris

MCSPACE: inferring microbiome spatiotemporal dynamics from high-throughput co-localization data MCSPACE：从高通量共定位数据推断微生物组时空动态

Microbiome

IF12.7

2025-12-12

OAAI

Gurdip Uppal; Guillaume Urtecho; Miles Richardson; Isin Y. Comba; Jeongchan Lee; Thomas Moody; Harris H. Wang; Georg K. Gerber

Combinatorial protein engineering identifies potent CRISPR activators with reduced toxicity 组合蛋白质工程鉴定出具有降低毒性的强效CRISPR激活因子

Nature Communications

IF15.7

2025-11-20

OAAI

Marla Giddins; Alexander F. Kratz; Mark B. De Los Santos; Antoine Forget; Richa Tiwari; Gwendolyn Jang; Tomasz Blazejewski; Chuyan Qin; Yiming Huang; Yeh-Hsing Lao; Thomas Falconer; Kam. W. Leong; Nevan Krogan; Max Staller; Harris Wang; Lai Wei; Alejandro Chavez

Fecal exfoliome sequencing captures immune dynamics of the healthy and inflamed gut 粪便表皮测序捕获健康和发炎肠道的免疫动力学

Nature Biotechnology

IF41.7

2025-11-17

PREAI

Yiming Huang; Yiwei Sun; Carlotta Ronda; Chrystal F. Mavros; Jing Li; Justin Jacobse; Lei H. Huang; Samuel J. Resnick; Marla Giddins; Daniel E. Freedberg; Alejandro Chavez; Jeremy A. Goettel; Harris H. Wang

Metagenomic editing of commensal bacteria in vivo using CRISPR-associated transposases 利用CRISPR相关转座酶对共生细菌进行原位元基因组编辑

Science

IF45.8

2025-11-13

PREAI

Diego Rivera Gelsinger; Carlotta Ronda; Junjie Ma; Om B. Kar; Madeline Edwards; Yiming Huang; Chrystal F. Mavros; Yiwei Sun; Tyler Perdue; Phuc Leo Vo; Ivaylo I. Ivanov; Samuel H. Sternberg; Harris H. Wang

Engineered probiotic restores GLP-1 signaling to ameliorate fiber-deficiency exacerbated colitis 工程益生菌恢复GLP-1信号以改善纤维缺乏加剧的结肠炎

Science Advances

IF12.5

2025-11-07

PREAI

Leonie Brockmann; Carlotta Ronda; Logan T. Schwanz; Yiming Qu; Daniel W. Shneider; Chrystal F. Mavros; Ivaylo I. Ivanov; Govind Bhagat; Harris H. Wang

Precise virulence inactivation using a CRISPR-associated transposase for combating Enterobacteriaceae gut pathogens 利用CRISPR相关转座酶对肠杆菌科肠道病原体进行精确毒力失活以对抗其危害

Nature Biomedical Engineering

IF26.6

2025-07-18

PREAI

Carlotta Ronda; Tyler Perdue; Logan Schwanz; Diego Rivera Gelsinger; Leonie Brockmann; Andrew Kaufman; Yiming Huang; Samuel H. Sternberg; Harris H. Wang

Bacteria Engineered to Produce Serotonin Modulate Host Intestinal Physiology

ACS SYNTHETIC BIOLOGY

IF3.9

2024-11-27

PREAI

Mavros, Chrystal F.; Bongers, Mareike; Neergaard, Frederik B. F.; Cusimano, Frank; Sun, Yiwei; Kaufman, Andrew; Richardson, Miles; Kammler, Susanne; Kristensen, Mette; Sommer, Morten O. A.; Wang, Harris H.

Spatiotemporal dynamics during niche remodeling by super-colonizing microbiota in the mammalian gut 哺乳动物肠道中超定殖微生物群在生态位重塑过程中的时空动态

CELL SYSTEMS

IF7.7

2024-11-01

OAAI

Urtecho, Guillaume; Moody, Thomas; Huang, Yiming; Sheth, Ravi U.; Richardson, Miles; Descamps, Helene C.; Kaufman, Andrew; Lekan, Opeyemi; Zhang, Zetian; Velez-Cortes, Florencia; Qu, Yiming; Cohen, Lucas; Ricaurte, Deirdre; Gibson, Travis E.; Gerber, Georg K.; Thaiss, Christoph A.; Wang, Harris H.

Shifts in Serum Bile Acid Profiles Associated With Barrett's Esophagus and Stages of Progression to Esophageal Adenocarcinoma 与Barrett食管和进展为食管腺癌的阶段相关的血清胆汁酸谱的变化

CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY

IF3

2024-10-01

OAAI

Kumar, Aarti; Gwalani, Pranav; Iyer, Prasad G.; Wang, Kenneth K.; Falk, Gary W.; Ginsberg, Gregory G.; Lightdale, Charles J.; Del Portillo, Armando; Lagana, Stephen M.; Li, Yun; Li, Hongzhe; Genkinger, Jeanine; Jin, Zhezhen; Rustgi, Anil K.; Wang, Timothy C.; Wang, Harris H.; Quante, Michael; Abrams, Julian A.

Context-dependent role of group 3 innate lymphoid cells in mucosal protection

SCIENCE IMMUNOLOGY

IF16.3

2024-08-16

PREAI

Araujo, Leandro P.; Edwards, Madeline; Irie, Koichiro; Huang, Yiming; Kawano, Yoshinaga; Tran, Alexander; De Michele, Simona; Bhagat, Govind; Wang, Harris H.; Ivanov, Ivaylo I.

SARS-CoV-2 omicron BA.2.87.1 exhibits higher susceptibility to serum neutralization than EG.5.1 and JN.1

EMERGING MICROBES & INFECTIONS

IF7.5

2024-05-31

OAAI

Wang, Qian; Guo, Yicheng; Schwanz, Logan T.; Mellis, Ian A.; Sun, Yiwei; Qu, Yiming; Urtecho, Guillaume; Valdez, Riccardo; Stoneman, Emily; Gordon, Aubree; Wang, Harris H.; Ho, David D.; Liu, Lihong

Bacterial genome engineering using CRISPR-associated transposases

NATURE PROTOCOLS

IF16

2024-01-12

OAAI

Gelsinger, Diego Rivera; Vo, Phuc Leo H.; Klompe, Sanne E.; Ronda, Carlotta; Wang, Harris H.; Sternberg, Samuel H.

Intestinal microbiota-specific Th17 cells possess regulatory properties and suppress effector T cells via c-MAF and IL-10

IMMUNITY

IF26.3

2023-12-01

PREAI

Brockmann, Leonie; Tran, Alexander; Huang, Yiming; Edwards, Madeline; Ronda, Carlotta; Wang, Harris H.; Ivanov, Ivaylo I.

Fast and efficient template-mediated synthesis of genetic variants

NATURE METHODS

IF32.1

2023-05-01

OAAI

Liu, Liyuan; Huang, Yiming; Wang, Harris H.

High-throughput microbial culturomics using automation and machine learning 使用自动化和机器学习的高通量微生物培养物

NATURE BIOTECHNOLOGY

IF41.7

2023-02-20

OAAI

Huang, Yiming; Sheth, Ravi U.; Zhao, Shijie; Cohen, Lucas A.; Dabaghi, Kendall; Moody, Thomas; Sun, Yiwei; Ricaurte, Deirdre; Richardson, Miles; Velez-Cortes, Florencia; Blazejewski, Tomasz; Kaufman, Andrew; Ronda, Carlotta; Wang, Harris H.

What is the key challenge in engineering microbiomes?

CELL SYSTEMS

IF7.7

2023-02-01

OAAI

Venturelli, Ophelia S.; Wang, Harris H.; Estrela, Sylvie; Huang, Kerwyn Casey; Ledesma-Amaro, Rodrigo; Fedorec, Alex J. H.; Stecher, Baeurorbel; Lawson, Christopher E.; Zarrinpar, Amir; Guo, Chun-Jun; Soyer, Orkun S.

Characterization and Spatial Mapping of the Human Gut Metasecretome

MSYSTEMS

IF4.6

2022-12-20

OAAI

Velez-Cortes, Florencia; Wang, Harris

Resurrecting essential amino acid biosynthesis in mammalian cells 恢复哺乳动物细胞中必需氨基酸的生物合成

ELIFE

IF0

2022-09-27

OAAI

Trolle, Julie; McBee, Ross M.; Kaufman, Andrew; Pinglay, Sudarshan; Berger, Henri; German, Sergei; Liu, Liyuan; Shen, Michael J.; Guo, Xinyi; Martin, J. Andrew; Pacold, Michael E.; Jones, Drew R.; Boeke, Jef D.; Wang, Harris H.

研究方向