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J

Joseph L. Watson

University of Washington

21H指数
61论文数
3.8K被引数
收录论文 13
发表时间
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Improved protein binder design using β-pairing targeted RFdiffusion利用β-配对靶向RFdiffusion改进蛋白质结合剂设计
errNature Communications
IF15.7
err2026-01-10
err0
errOAAI
errIsaac Sappington; Martin Toul; David S. Lee; Stephanie A. Robinson; Inna Goreshnik; Clara McCurdy; Tung Ching Chan; Nic Buchholz; Buwei Huang; Dionne Vafeados; Mariana Garcia-Sanchez; Nicole Roullier; Matthias Glögl; Christopher J. Kim; Joseph L. Watson; Susana Vázquez Torres; Koen H. G. Verschueren; Kenneth Verstraete; Cynthia S. Hinck; Melisa Benard-Valle; Brian Coventry; Jeremiah Nelson Sims; Green Ahn; Xinru Wang; Andrew P. Hinck; Timothy P. Jenkins; Hannele Ruohola-Baker; Steven M. Banik; Savvas N. Savvides; David Baker
err分享
err收藏
Accurate single-domain scaffolding of three nonoverlapping protein epitopes using deep learning利用深度学习对三个非重叠蛋白质表位进行精确的单域支架构建
errNature Chemical Biology
IF13.7
err2025-12-05
err0
errOAAI
errKarla M. Castro; Joseph L. Watson; Jue Wang; Joshua Southern; Reyhaneh Ayardulabi; Sandrine Georgeon; Stéphane Rosset; David Baker; Bruno E. Correia
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Atomically accurate de novo design of antibodies with RFdiffusion基于RFdiffusion的抗体原子级精确从头设计
errNature
IF48.5
err2025-11-05
err0
errOAAI
errNathaniel R. Bennett; Joseph L. Watson; Robert J. Ragotte; Andrew J. Borst; DéJenaé L. See; Connor Weidle; Riti Biswas; Yutong Yu; Ellen L. Shrock; Russell Ault; Philip J. Y. Leung; Buwei Huang; Inna Goreshnik; John Tam; Kenneth D. Carr; Benedikt Singer; Cameron Criswell; Basile I. M. Wicky; Dionne Vafeados; Mariana Garcia Sanchez; Ho Min Kim; Susana Vázquez Torres; Sidney Chan; Shirley M. Sun; Timothy T. Spear; Yi Sun; Keelan O’Reilly; John M. Maris; Nikolaos G. Sgourakis; Roman A. Melnyk; Chang C. Liu; David Baker
err分享
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Bottom-up design of Ca2+ channels from defined selectivity filter geometry从定义的选择性过滤器几何结构自下而上设计Ca2+通道
errNature
IF48.5
err2025-10-22
err0
PREAI
errYulai Liu; Connor Weidle; Ljubica Mihaljević; Joseph L. Watson; Zhe Li; Le Tracy Yu; Sagardip Majumder; Andrew J. Borst; Kenneth D. Carr; Ryan D. Kibler; Tamer M. Gamal El-Din; William A. Catterall; David Baker
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Diffusing protein binders to intrinsically disordered proteins将蛋白质结合剂扩散到本质上无序的蛋白质
errNature
IF48.5
err2025-07-30
err0
errOAAI
errCaixuan Liu; Kejia Wu; Hojun Choi; Hannah L. Han; Xueli Zhang; Joseph L. Watson; Green Ahn; Jason Z. Zhang; Sara Shijo; Lydia L. Good; Charlotte M. Fischer; Asim K. Bera; Alex Kang; Evans Brackenbrough; Brian Coventry; Derrick R. Hick; Seema Qamar; Xinting Li; Justin Decarreau; Stacey R. Gerben; Wei Yang; Inna Goreshnik; Dionne Vafeados; Xinru Wang; Mila Lamb; Analisa Murray; Sebastian Kenny; Magnus S. Bauer; Andrew N. Hoofnagle; Ping Zhu; Tuomas P. J. Knowles; David Baker
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A role for vessel-associated extracellular matrix proteins in multiple sclerosis pathology
errBRAIN PATHOLOGY
IF6.2
err2024-04-25
err1
errOAAI
errPisa, Marco; Watson, Joseph L.; Spencer, Jonathan I.; Niblett, Guy; Mahjoub, Yasamin; Lockhart, Andrew; Yates, Richard L.; Yee, Sydney A.; Hadley, Gina; Ruiz, Jennifer; Esiri, Margaret M.; Kessler, Benedict; Fischer, Roman; Deluca, Gabriele C.
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De novo design of pH-responsive self-assembling helical protein filaments
errNATURE NANOTECHNOLOGY
IF34.9
err2024-04-03
err7
errOAAI
errShen, Hao; Lynch, Eric M.; Akkineni, Susrut; Watson, Joseph L.; Decarreau, Justin; Bethel, Neville P.; Benna, Issa; Sheffler, William; Farrell, Daniel; Dimaio, Frank; Derivery, Emmanuel; De Yoreo, James J.; Kollman, Justin; Baker, David
err分享
err收藏
Protein Design Using Structure-Prediction Networks: AlphaFold and RoseTTAFold as Protein Structure Foundation Models
errcold spring harbor perspectives in medicine
IF8.4
err2024-03-04
err4
PREAI
errWang, Jue; Watson, Joseph L.; Lisanza, Sidney L.
err分享
err收藏
HEATR5B associates with dynein-dynactin and promotes motility of AP1-bound endosomal membranesHEATR5B与动力蛋白-动力蛋白结合并促进AP1-bound内体膜的运动
errEMBO JOURNAL
IF8.3
err2023-10-24
err2
errOAAI
errMadan, Vanesa; Albacete-Albacete, Lucas; Jin, Li; Scaturro, Pietro; Watson, Joseph L.; Muschalik, Nadine; Begum, Farida; Boulanger, Jerome; Bauer, Karl; Kiebler, Michael A.; Derivery, Emmanuel; Bullock, Simon L.
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Compensatory ion transport buffers daily protein rhythms to regulate osmotic balance and cellular physiology (vol 12, 6035, 2021)
errNATURE COMMUNICATIONS
IF15.7
err2021-11-24
err0
errOAAI
errStangherlin, Alessandra; Watson, Joseph L.; Wong, David C. S.; Barbiero, Silvia; Zeng, Aiwei; Seinkmane, Estere; Chew, Sew Peak; Beale, Andrew D.; Hayter, Edward A.; Guna, Alina; Inglis, Alison J.; Putker, Marrit; Bartolami, Eline; Matile, Stefan; Lequeux, Nicolas; Pons, Thomas; Day, Jason; van Ooijen, Gerben; Voorhees, Rebecca M.; Bechtold, David A.; Derivery, Emmanuel; Edgar, Rachel S.; Newham, Peter; O'Neill, John S.
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Compensatory ion transport buffers daily protein rhythms to regulate osmotic balance and cellular physiology代偿性离子转运缓冲每日蛋白质节律调节渗透平衡和细胞生理
errNATURE COMMUNICATIONS
IF15.7
err2021-10-15
err27
errOAAI
errStangherlin, Alessandra; Watson, Joseph L.; Wong, David C. S.; Barbiero, Silvia; Zeng, Aiwei; Seinkmane, Estere; Chew, Sew Peak; Beale, Andrew D.; Hayter, Edward A.; Guna, Alina; Inglis, Alison J.; Putker, Marrit; Bartolami, Eline; Matile, Stefan; Lequeux, Nicolas; Pons, Thomas; Day, Jason; van Ooijen, Gerben; Voorhees, Rebecca M.; Bechtold, David A.; Derivery, Emmanuel; Edgar, Rachel S.; Newham, Peter; O'Neill, John S.
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High-efficacy subcellular micropatterning of proteins using fibrinogen anchors
errJOURNAL OF CELL BIOLOGY
IF6.4
err2021-01-08
err13
errOAAI
errWatson, Joseph L.; Aich, Samya; Oller-Salvia, Benjami; Drabek, Andrew A.; Blacklow, Stephen C.; Chin, Jason; Derivery, Emmanuel
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Protein Stability Buffers the Cost of Translation Attenuation following eIF2α Phosphorylation
errCELL REPORTS
IF6.9
err2020-09-01
err17
errOAAI
errSchneider, Kim; Nelson, Geoffrey Michael; Watson, Joseph Luke; Morf, Jorg; Dalglish, Maximillian; Luh, Laura Martina; Weber, Annika; Bertolotti, Anne
err分享
err收藏

研究方向

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合作学者
合作期刊
W
William A. Catterall
H 指数: 162 · 论文数: 652
李金 封面图
李金 (Jin Li)
H 指数: 149 · 论文数: 4.5K
J
John M. Maris
H 指数: 115 · 论文数: 1.4K
T
Tuomas P. J. Knowles
H 指数: 103 · 论文数: 730
M
Margaret M. Esiri
H 指数: 91 · 论文数: 407
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