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Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase Xie, Stanley C.; Wang, Yinuo; Morton, Craig J.; Metcalfe, Riley D.; Dogovski, Con; Pasaje, Charisse Flerida A.; Dunn, Elyse; Luth, Madeline R.; Kumpornsin, Krittikorn; Istvan, Eva S.; Park, Joon Sung; Fairhurst, Kate J.; Ketprasit, Nutpakal; Yeo, Tomas; Yildirim, Okan; Bhebhe, Mathamsanqa N.; Klug, Dana M.; Rutledge, Peter J.; Godoy, Luiz C.; Dey, Sumanta; De Souza, Mariana Laureano; Siqueira-Neto, Jair L.; Du, Yawei; Puhalovich, Tanya; Amini, Mona; Shami, Gerry; Loesbanluechai, Duangkamon; Nie, Shuai; Williamson, Nicholas; Jana, Gouranga P.; Maity, Bikash C.; Thomson, Patrick; Foley, Thomas; Tan, Derek S.; Niles, Jacquin C.; Han, Byung Woo; Goldberg, Daniel E.; Burrows, Jeremy; Fidock, David A.; Lee, Marcus C. S.; Winzeler, Elizabeth A.; Griffin, Michael D. W.; Todd, Matthew H.; Tilley, Leann 分享 收藏
Open Source Antibiotics: Simple Diarylimidazoles Are Potent against Methicillin-Resistant Staphylococcus aureus 开源抗生素: 简单的二芳基咪唑对耐甲氧西林金黄色葡萄球菌有效 Klug, Dana M.; Tse, Edwin G.; Silva, Daniel G.; Cao, Yafeng; Charman, Susan A.; Chauhan, Jyoti; Crighton, Elly; Dichiara, Maria; Drake, Chris; Drewry, David; da Silva Emery, Flavio; Ferrins, Lori; Graves, Lee; Hopkins, Emily; Kresina, Thomas A. C.; Lorente-Macias, Alvaro; Perry, Benjamin; Phipps, Richard; Quiroga, Bruno; Quotadamo, Antonio; Sabatino, Giada N.; Sama, Anthony; Schatzlein, Andreas; Simpson, Quillon J.; Steele, Jonathan; Shanu-Wilson, Julia; Sjo, Peter; Stapleton, Paul; Swain, Christopher J.; Vaideanu, Alexandra; Xie, Huanxu; Zuercher, William; Todd, Matthew H. 分享 收藏
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Structure-Property Optimization of a Series of Imidazopyridines for Visceral Leishmaniasis Dichiara, Maria; Simpson, Quillon J.; Quotadamo, Antonio; Jalani, Hitesh B.; Huang, Anson X.; Millard, Caroline C.; Klug, Dana M.; Tse, Edwin G.; Todd, Matthew H.; Silva, Daniel Gedder; Emery, Flavio da Silva; Carlson, J. Eric; Zheng, Shao-Liang; Vleminckx, Margot; Matheeussen, An; Caljon, Guy; Pollastri, Michael P.; Sjo, Peter; Perry, Benjamin; Ferrins, Lori 分享 收藏
Target 2035-an update on private sector contributions Ackloo, Suzanne; Antolin, Albert A.; Bartolome, Jose Manuel; Beck, Hartmut; Bullock, Alex; Betz, Ulrich A. K.; Boettcher, Jark.; Brown, Peter J.; Chaturvedi, Menorca; Crisp, Alisa; Daniels, Danette; Dreher, Jan; Edfeldt, Kristina; Edwards, Aled M.; Egner, Ursula; Elkins, Jon; Fischer, Christian; Glendorf, Tine; Goldberg, Steven; Hartung, Ingo V.; Hillisch, Alexander; Homan, Evert; Knapp, Stefan; Koester, Markus; Kraemer, Oliver; Llaveria, Josep; Lessel, Uta; Lindemann, Sven; Linderoth, Lars; Matsui, Hisanori; Michel, Maurice; Montel, Florian; Mueller-Fahrnow, Anke; Mueller, Susanne; Owen, Dafydd R.; Saikatendu, Kumar Singh; Santhakumar, Vijayaratnam; Sanderson, Wendy; Scholten, Cora; Schapira, Matthieu; Sharma, Sujata; Shireman, Brock; Sundstrom, Michael; Todd, Matthew H.; Tredup, Claudia; Venable, Jennifer; Willson, Timothy M.; Arrowsmith, Cheryl H. 分享 收藏
Perphenazine-Macrocycle Conjugates Rapidly Sequester the Aβ42 Monomer and Prevent Formation of Toxic Oligomers and Amyloid Ball, Sarah R.; Adamson, Julius S. P.; Sullivan, Michael A.; Zimmermann, Manuela R.; Lo, Victor; Sanz-Hernandez, Maximo; Jiang, Xiaofan; Kwan, Ann H.; McKenzie, Andre D. J.; Werry, Eryn L.; Knowles, Tuomas P. J.; Kassiou, Michael; Meisl, Georg; Todd, Matthew H.; Rutledge, Peter J.; Sunde, Margaret 分享 收藏
CACHE (Critical Assessment of Computational Hit-finding Experiments): A public-private partnership benchmarking initiative to enable the development of computational methods for hit-finding CACHE (计算命中发现实验的关键评估): 一项公私合作伙伴关系基准计划，旨在开发命中发现的计算方法 Ackloo, Suzanne; Al-awar, Rima; Amaro, Rommie E.; Arrowsmith, Cheryl H.; Azevedo, Hatylas; Batey, Robert A.; Bengio, Yoshua; Betz, Ulrich A. K.; Bologa, Cristian G.; Chodera, John D.; Cornell, Wendy D.; Dunham, Ian; Ecker, Gerhard F.; Edfeldt, Kristina; Edwards, Aled M.; Gilson, Michael K.; Gordijo, Claudia R.; Hessler, Gerhard; Hillisch, Alexander; Hogner, Anders; Irwin, John J.; Jansen, Johanna M.; Kuhn, Daniel; Leach, Andrew R.; Lee, Alpha A.; Lessel, Uta; Morgan, Maxwell R.; Moult, John; Muegge, Ingo; Oprea, Tudor, I; Perry, Benjamin G.; Riley, Patrick; Rousseaux, Sophie A. L.; Saikatendu, Kumar Singh; Santhakumar, Vijayaratnam; Schapira, Matthieu; Scholten, Cora; Todd, Matthew H.; Vedadi, Masoud; Volkamer, Andrea; Willson, Timothy M. 分享 收藏
Screening the pandemic response box identified benzimidazole carbamates, Olorofim and ravuconazole as promising drug candidates for the treatment of eumycetoma Lim, Wilson; Nyuykonge, Bertrand; Eadie, Kimberly; Konings, Mickey; Smeets, Juli; Fahal, Ahmed; Bonifaz, Alexandro; Todd, Matthew; Perry, Benjamin; Samby, Kirandeep; Burrows, Jeremy; Verbon, Annelies; van de Sande, Wendy 分享 收藏
Target 2035-update on the quest for a probe for every protein Mueller, Susanne; Ackloo, Suzanne; Al Chawaf, Arij; Al-Lazikani, Bissan; Antolin, Albert; Baell, Jonathan B.; Beck, Hartmut; Beedie, Shaunna; Betz, Ulrich A. K.; Bezerra, Gustavo Arruda; Brennan, Paul E.; Brown, David; Brown, Peter J.; Bullock, Alex N.; Carter, Adrian J.; Chaikuad, Apirat; Chaineau, Mathilde; Ciulli, Alessio; Collins, Ian; Dreher, Jan; Drewry, David; Edfeldt, Kristina; Edwards, Aled M.; Egner, Ursula; Frye, Stephen, V; Fuchs, Stephen M.; Hall, Matthew D.; Hartung, Ingo, V; Hillisch, Alexander; Hitchcock, Stephen H.; Homan, Evert; Kannan, Natarajan; Kiefer, James R.; Knapp, Stefan; Kostic, Milka; Kubicek, Stefan; Leach, Andrew R.; Lindemann, Sven; Marsden, Brian D.; Matsui, Hisanori; Meier, Jordan L.; Merk, Daniel; Michel, Maurice; Morgan, Maxwell R.; Mueller-Fahrnow, Anke; Owen, Dafydd R.; Perry, Benjamin G.; Rosenberg, Saul H.; Saikatendu, Kumar Singh; Schapira, Matthieu; Scholten, Cora; Sharma, Sujata; Simeonov, Anton; Sundstrom, Michael; Superti-Furga, Giulio; Todd, Matthew H.; Tredup, Claudia; Vedadi, Masoud; von Delft, Frank; Willson, Timothy M.; Winter, Georg E.; Workman, Paul; Arrowsmith, Cheryl H. 分享 收藏
An Open Drug Discovery Competition: Experimental Validation of Predictive Models in a Series of Novel Antimalarials Tse, Edwin G.; Aithani, Laksh; Anderson, Mark; Cardoso-Silva, Jonathan; Cincilla, Giovanni; Conduit, Gareth J.; Galushka, Mykola; Guan, Davy; Hallyburton, Irene; Irwin, Benedict W. J.; Kirk, Kiaran; Lehane, Adele M.; Lindblom, Julia C. R.; Lui, Raymond; Matthews, Slade; McCulloch, James; Motion, Alice; Ng, Ho Leung; Oeren, Mario; Robertson, Murray N.; Spadavecchio, Vito; Tatsis, Vasileios A.; van Hoorn, Willem P.; Wade, Alexander D.; Whitehead, Thomas M.; Willis, Paul; Todd, Matthew H. 分享 收藏
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Nonclassical Phenyl Bioisosteres as Effective Replacements in a Series of Novel Open-Source Antimalarials Tse, Edwin G.; Houston, Sevan D.; Williams, Craig M.; Savage, G. Paul; Rendina, Louis M.; Hallyburton, Irene; Anderson, Mark; Sharma, Raman; Walker, Gregory S.; Obach, R. Scott; Todd, Matthew H. 分享 收藏
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