Kirill Alexandrov - Publications, H-index & Citations

Kirill Alexandrov

ARC Centre of Excellence in Synthetic Biology

54H指数

276论文数

9.6K被引数

收录论文 106

发表时间

Publisher Correction: Artificial allosteric protein switches with machine-learning-designed receptors 出版者更正：具有机器学习设计受体的合成别构蛋白质开关

Nature Biotechnology

IF41.7

2026-07-20

OAAI

Zhong Guo; Oleh Smutok; Gyu Rie Lee; Zhenling Cui; Haocheng Qianzhu; Monika Kish; Cagla Ergun Ayva; Kejia Wu; Roxane Mutschler; Colin J. Jackson; Maria M. Fiorito; Andrew C. Warden; Oliver B. Smith; Alfredo Quijano-Rubio; Thomas Huber; Jonathan J. Phillips; Gottfried Otting; Evgeny Katz; David Baker; Kirill Alexandrov

Artificial allosteric protein switches with machine-learning-designed receptors 具有机器学习设计的受体的人工变构蛋白质开关

Nature Biotechnology

IF41.7

2026-04-15

OAAI

Zhong Guo; Oleh Smutok; Gyu Rie Lee; Zhenling Cui; Haocheng Qianzhu; Monika Kish; Cagla Ergun yva; Kejia Wu; Roxane Mutschler; Colin J. Jackson; Maria M. Fiorito; Andrew C. Warden; Oliver B. Smith; Alfredo Quijano-Rubio; Thomas Huber; Jonathan J. Phillips; Gottfried Otting; Evgeny Katz; David Baker; Kirill Alexandrov

Cooperative Binding Domains Enhance Sensitivity and Overcome the Hook Effect in Two-Component Protein Biosensors 协同结合域增强两元件蛋白生物传感器的灵敏性并克服钩状效应

ACS Sensors acs-se

IF0

2026-03-09

OAAI

Roxane Mutschler; Alessandro T. Caputo; Zhong Guo; Maria Micaela Fiorito; Irfan Farabi Hayat; Sophia Newton; Xi Zhang; Nuwan Karunathilaka; Carla Duval; Halai Brazel; Wandy Chan; Karam Kostner; Dariusz Korczyk; Daniel Kwaku Abankwa; John J. Atherton; Andrew J.S. Coats; Chamindie Punyadeera; Kirill Alexandrov; Zhenling Cui

Rare earth elements in biology: From biochemical curiosity to solutions for extractive industries

MICROBIAL BIOTECHNOLOGY

IF5.2

2024-06-03

OAAI

Rocha, Raquel A.; Alexandrov, Kirill; Scott, Colin

Development of Lyophilized Eukaryotic Cell-Free Protein Expression System Based on Leishmania tarentolae

ACS SYNTHETIC BIOLOGY

IF3.9

2024-01-24

PREAI

Alfaro-Palma, Juan; Johnston, Wayne A.; Behrendorff, James; Cui, Zhenling; Moradi, Shayli Varasteh; Alexandrov, Kirill

Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice (vol 6, e21221, 2017)

ELIFE

IF0

2023-08-08

OAAI

Overman, Jeroen; Fontaine, Frank; Moustaqil, Mehdi; Mittal, Deepak; Sierecki, Emma; Sacilotto, Natalia; Zuegg, Johannes; Robertson, Avril A. B.; Holmes, Kelly; Salim, Angela A.; Mamidyala, Sreeman; Butler, Mark S.; Robinson, Ashley S.; Lesieur, Emmanuelle; Johnston, Wayne; Alexandrov, Kirill; Black, Brian L.; Hogan, Benjamin M.; De Val, Sarah; Capon, Robert J.; Carroll, Jason S.; Bailey, Timothy L.; Koopman, Peter; Jauch, Ralf; Cooper, Matthew A.; Gambin, Yann; Francois, Mathias

Development of epistatic YES and AND protein logic gates and their assembly into signalling cascades

NATURE NANOTECHNOLOGY

IF34.9

2023-07-27

PREAI

Guo, Zhong; Smutok, Oleh; Ayva, Cagla Ergun; Walden, Patricia; Parker, Jake; Whitfield, Jason; Vickers, Claudia E.; Ungerer, Jacobus P. J.; Katz, Evgeny; Alexandrov, Kirill

In Vitro Reconstitution and Analysis of SARS-CoV-2/Host Protein-Protein Interactions

ACS OMEGA

IF4.3

2023-07-06

OAAI

Moradi, Shayli Varasteh; Wu, Yue; Walden, Patricia; Cui, Zhenling; Johnston, Wayne A.; Petrov, Dmitri; Alexandrov, Kirill

Fluorometric biosensing of α-amylase using an artificial allosteric biosensor immobilized on nanostructured interface

TALANTA

IF6.1

2023-04-01

OAAI

Wells, Paulina K.; Smutok, Oleh; Guo, Zhong; Alexandrov, Kirill; Katz, Evgeny

In vivo protein-based biosensors: seeing metabolism in real time (vol 41, pg 19, 2023)

TRENDS IN BIOTECHNOLOGY

IF14.9

2023-02-01

OAAI

Alexandrov, Kirill; Vickers, Claudia E.

HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages HDAC7是一种免疫代谢开关，可将巨噬细胞中抗菌与炎症反应的危险信号进行三分。

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-01-17

OAAI

Gupta, Kaustav Das; Ramnath, Divya; von Pein, Jessica B.; Curson, James E. B.; Wang, Yizhuo; Abrol, Rishika; Kakkanat, Asha; Moradi, Shayli Varasteh; Gunther, Kimberley S.; Murthy, Ambika M. V.; Stocks, Claudia J.; Kapetanovic, Ronan; Reid, Robert C.; Iyer, Abishek; Ilka, Zoe C.; Nauseef, William M.; Plan, Manuel; Luo, Lin; Stow, Jennifer L.; Schroder, Kate; Karunakaran, Denuja; Alexandrov, Kirill; Shakespear, Melanie R.; Schembri, Mark A.; Fairlie, David P.; Sweet, Matthew J.

In vivo protein-based biosensors: seeing metabolism in real time

TRENDS IN BIOTECHNOLOGY

IF14.9

2023-01-01

PREAI

Alexandrov, Kirill; Vickers, Claudia E.

Novel antiinflammatory biologics shaped by parasite-host coevolution

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-08-29

OAAI

Ryan, Stephanie M.; Ruscher, Roland; Johnston, Wayne A.; Pickering, Darren A.; Kennedy, Malcolm W.; Smith, Brian O.; Jones, Linda; Buitrago, Geraldine; Field, Matt A.; Esterman, Adrian J.; McHugh, Connor P.; Browne, Daniel J.; Cooper, Martha M.; Ryan, Rachael Y. M.; Doolan, Denise L.; Engwerda, Christian R.; Miles, Kim; Mitreva, Makedonka; Croese, John; Rahman, Tony; Alexandrov, Kirill; Giacomin, Paul R.; Loukas, Alex

The present and the future of protein biosensor engineering

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2022-08-01

PREAI

Jackson, Colin; Anderson, Alisha; Alexandrov, Kirill

Nanostructured Interface Loaded with Chimeric Enzymes for Fluorimetric Quantification of Cyclosporine A and FK506

ANALYTICAL CHEMISTRY

IF6.7

2022-05-11

PREAI

Wells, Paulina K.; Smutok, Oleh; Guo, Zhong; Alexandrov, Kirill; Katz, Evgeny

The transmembrane adapter SCIMP recruits tyrosine kinase Syk to phosphorylate Toll-like receptors to mediate selective inflammatory outputs

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-05-01

OAAI

Liu, Liping; Lucas, Richard M.; Nanson, Jeffrey D.; Li, Yan; Whitfield, Jason; Curson, James E. B.; Tuladhar, Neeraj; Alexandrov, Kirill; Mobli, Mehdi; Sweet, Matthew J.; Kobe, Bostjan; Stow, Jennifer L.; Luo, Lin

Engineering and exploiting synthetic allostery of NanoLuc luciferase

NATURE COMMUNICATIONS

IF15.7

2022-02-10

OAAI

Guo, Zhong; Parakra, Rinky D.; Xiong, Ying; Johnston, Wayne A.; Walden, Patricia; Edwardraja, Selvakumar; Moradi, Shayli Varasteh; Ungerer, Jacobus P. J.; Ai, Hui-wang; Phillips, Jonathan J.; Alexandrov, Kirill

Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system

NATURE COMMUNICATIONS

IF15.7

2022-01-11

OAAI

Wu, Yue; Cui, Zhenling; Huang, Yen-Hua; de Veer, Simon J.; Aralov, Andrey V.; Guo, Zhong; Moradi, Shayli V.; Hinton, Alexandra O.; Deuis, Jennifer R.; Guo, Shaodong; Chen, Kai-En; Collins, Brett M.; Vetter, Irina; Herzig, Volker; Jones, Alun; Cooper, Matthew A.; King, Glenn F.; Craik, David J.; Alexandrov, Kirill; Mureev, Sergey

Circular Permutated PQQ-Glucose Dehydrogenase as an Ultrasensitive Electrochemical Biosensor

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2021-12-28

PREAI

Guo, Zhong; Smutok, Oleh; Johnston, Wayne A.; Ayva, Cagla Ergun; Walden, Patricia; McWhinney, Brett; Ungerer, Jacobus P. J.; Melman, Artem; Katz, Evgeny; Alexandrov, Kirill

Design of a methotrexate-controlled chemical dimerization system and its use in bio-electronic devices

NATURE COMMUNICATIONS

IF15.7

2021-12-08

OAAI

Guo, Zhong; Smutok, Oleh; Johnston, Wayne A.; Walden, Patricia; Ungerer, Jacobus P. J.; Peat, Thomas S.; Newman, Janet; Parker, Jake; Nebl, Tom; Hepburn, Caryn; Melman, Artem; Suderman, Richard J.; Katz, Evgeny; Alexandrov, Kirill

研究方向