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A

Amanda C. Poholek

university of pittsburgh

34H指数
103论文数
8.2K被引数
收录论文 52
发表时间
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The genesis of cutaneous neurogenic inflammation is a multi-step process requiring dendritic cell aggregation皮肤神经源性炎症的起源是一个多步骤过程，需要树突状细胞聚集
errImmunity
IF26.3
err2026-08-11
err0
PREAI
errChien-Sin Chen; Jacob E. Gillis; Jonathan A. Cohen; Alexandra R. Glathar; Yijia Chen; Eric S. Weiss; Lindsay M. McKendrick; Caitlin O. Bacon; Colton J. Smith; Nick J. Spencer; Isaac M. Chiu; Brian M. Davis; Tina L. Sumpter; Anthony R. Cillo; Amanda C. Poholek; Daniel H. Kaplan
err分享
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A unified network systems approach uncovers a core program underlying T follicular helper cell differentiation一种统一的网络系统方法揭示了T滤泡辅助细胞分化的核心程序
errNature Communications
IF15.7
err2026-07-22
err0
errOAAI
errAlisa A. Omelchenko; Syed A. Rahman; Alyson Wang; Tracy Tabib; Vinayak V. Viswanadham; Grace J. Yuen; Perla M. Del Rio Estrada; Valentino D’Onofrio; Yijia Chen; Na Sun; Hamid Mattoo; Swapnil Keshari; Chinmay V. Gadiraju; Gonzalo Salgado; Maribel Soto-Nava; Lady Ruiz-Carbajal; Dafne Díaz-Rivera; Santiago Ávila-Ríos; Sudhir P. Kasturi; Susan P. Ribeiro; Mark J. Shlomchik; Amanda C. Poholek; Shiv Pillai; Rebecca A. Elsner; Vinay S. Mahajan; Jishnu Das
err分享
err收藏
IL-9 and Blimp-1 protect the transcriptional identity of group 2 innate lymphocytes in allergic asthmaIL-9和Blimp-1保护过敏性哮喘中2型固有淋巴细胞的转录特性
errNature Immunology
IF27.6
err2026-04-01
err0
PREAI
errZheng, Yibo; Giri, Shilpi; Zhang, Jinyi; Chen, Yijia; Yang, Aaron; Kale, Sagar L.; Beeravolu, Harshita; Pannucci, Abbe; Marinov, Anthony D.; Tilstra, Jeremy S.; He, Kun; Creech, Arianna; Schwartz, Daniella M.; Gottschalk, Rachel A.; Bouladoux, Nicolas; Belkaid, Yasmine; Cillo, Anthony R.; Ray, Anuradha; Poholek, Amanda C.
err分享
err收藏
Krüppel-like factor 4 regulates the survival and function of intestinal CD4+tissue resident memory T cells
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errSi, Xu; Yang, Deyi; Colon, Emmanuel Leon; Sheridan, Brain; Kane, Lawrence; Poholek, Amanda; Bhattacharjee, Amrita; Hand, Timothy W.
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Redirecting glucose flux during in vitro expansion generates epigenetically and metabolically superior T cells for cancer immunotherapy在体外扩增过程中重定向葡萄糖流，可产生表观遗传学和代谢学上更优越的T细胞，用于癌症免疫治疗
errCELL METABOLISM
IF30.9
err2025-01-01
err0
PREAI
errFrisch, Andrew T.; Wang, Yiyang; Xie, Bingxian; Yang, Aaron; Ford, B. Rhodes; Joshi, Supriya; Kedziora, Katarzyna M.; Peralta, Ronal; Wilfahrt, Drew; Mullett, Steven J.; Spahr, Supriya Kellie; Lontos, Konstantinos; Jana, Jessica A.; Dean, Victoria G.; Gunn, William G.; Gelhaus, Stacy; Poholek, Amanda C.; Rivadeneira, Dayana B.; Delgoffe, Greg M.
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Dysfunction of exhausted T cells is enforced by MCT11-mediated lactate metabolism乳酸代谢MCT11-mediated增强了疲惫的T细胞功能障碍
errNATURE IMMUNOLOGY
IF27.6
err2024-11-08
err1
errOAAI
errPeralta, Ronal M.; Xie, Bingxian; Lontos, Konstantinos; Nieves-Rosado, Hector; Spahr, Kellie; Joshi, Supriya; Ford, B. Rhodes; Quann, Kevin; Frisch, Andrew T.; Dean, Victoria; Philbin, Mary; Cillo, Anthony R.; Gingras, Sebastian; Poholek, Amanda C.; Kane, Lawrence P.; Rivadeneira, Dayana B.; Delgoffe, Greg M.
err分享
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Spatial microniches of IL-2 combine with IL-10 to drive lung migratory TH2 cells in response to inhaled allergenIL-2的空间微区与IL-10结合以驱动肺迁移TH2细胞对吸入过敏原的反应
errNATURE IMMUNOLOGY
IF27.6
err2024-10-11
err0
PREAI
errHe, Kun; Xiao, Hanxi; MacDonald, William A.; Mehta, Isha; Kishore, Akash; Vincent, Augusta; Xu, Zhongli; Ray, Anuradha; Chen, Wei; Weaver, Casey T.; Lambrecht, Bart N.; Das, Jishnu; Poholek, Amanda C.
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Systems immunology approaches to study T cells in health and disease
errNPJ SYSTEMS BIOLOGY AND APPLICATIONS
IF3.5
err2024-10-09
err0
errOAAI
errYang, Aaron; Poholek, Amanda C.
err分享
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Postprandial changes to systemic metabolism imprint durable changes on T cell immune responses
errJOURNAL OF IMMUNOLOGY
IF3.4
err2024-05-01
err0
PREAI
errKumar, Alok; Rivadienera, Dayana; Delgoffe, Greg; Poholek, Amanda; Kohan, Alison
err分享
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Sustained cross-talk between donor T cells and IL-33+stromal cells maintains CD4 T cell differentiation and determines GVHD outcomes
errJOURNAL OF IMMUNOLOGY
IF3.4
err2024-05-01
err0
PREAI
errDwyer, Gaelen; Mathews, Lisa; Chalmers, Bailey; Naaz, Afsana; Poholek, Amanda; Sacirbegovic, Faruk; Shlomchik, Warren; Turnquist, Heth
err分享
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Innovative super-resolution in spatial transcriptomics: a transformer model exploiting histology images and spatial gene expression空间转录组学中的创新超分辨率: 利用组织学图像和空间基因表达的转换器模型
errBRIEFINGS IN BIOINFORMATICS
IF7.7
err2024-03-02
err3
errOAAI
errZhao, Chongyue; Xu, Zhongli; Wang, Xinjun; Tao, Shiyue; MacDonald, William A.; He, Kun; Poholek, Amanda C.; Chen, Kong; Huang, Heng; Chen, Wei
err分享
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SLIDE: Significant Latent Factor Interaction Discovery and Exploration across biological domains
errNATURE METHODS
IF32.1
err2024-02-19
err10
PREAI
errRahimikollu, Javad; Xiao, Hanxi; Rosengart, AnnaElaine; Rosen, Aaron B. I.; Tabib, Tracy; Zdinak, Paul M.; He, Kun; Bing, Xin; Bunea, Florentina; Wegkamp, Marten; Poholek, Amanda C.; Joglekar, Alok V.; Lafyatis, Robert A.; Das, Jishnu
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Paired immunoglobulin-like receptor B is an entry receptor for mammalian orthoreovirus
errNATURE COMMUNICATIONS
IF15.7
err2023-05-05
err10
errOAAI
errShang, Pengcheng; Simpson, Joshua D.; Taylor, Gwen M.; Sutherland, Danica M.; Welsh, Olivia L.; Aravamudhan, Pavithra; Natividade, Rita Dos Santos; Schwab, Kristina; Michel, Joshua J.; Poholek, Amanda C.; Wu, Yijen; Rajasundaram, Dhivyaa; Koehler, Melanie; Alsteens, David; Dermody, Terence S.
err分享
err收藏
Autocrine pro-inflammatory IL-10 initiates lung-specific Th2 responses to inhaled allergen to induce allergic asthma
errJOURNAL OF IMMUNOLOGY
IF3.4
err2023-05-01
err0
errOAAI
errHe, Kun; Xu, Zhongli; MacDonald, William A.; Ray, Anuradha; Chen, Wei; Lambrecht, Bart N.; Poholek, Amanda
err分享
err收藏
To loop or not to loop? CNS-28 is the answer
errIMMUNITY
IF26.3
err2023-05-01
err0
errOAAI
errYang, Aaron; Poholek, Amanda C.
err分享
err收藏
Regulation and Immunotherapeutic Targeting of the Epigenome in Exhausted CD8 T Cell Responses
errJOURNAL OF IMMUNOLOGY
IF3.4
err2023-04-01
err4
errOAAI
errFord, B. Rhodes; Poholek, Amanda C.
err分享
err收藏
Excess Dietary Sugar Alters Colonocyte Metabolism and Impairs the Proliferative Response to Damage
errCELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY
IF7.4
err2023-01-01
err8
errOAAI
errBurr, Ansen H. P.; Ji, Junyi; Ozler, Kadir; Mentrup, Heather L.; Eskiocak, Onur; Yueh, Brian; Cumberland, Rachel; V. Menk, Ashley; Rittenhouse, Natalie; Marshall, Chris W.; Chiaranunt, Pailin; Zhang, Xiaoyi; Mullinax, Lauren; Overacre-Delgoffe, Abigail; Cooper, Vaughn S.; Poholek, Amanda C.; Delgoffe, Greg M.; Mollen, Kevin P.; Beyaz, Semir; Hand, Timothy W.
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Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity
errNATURE IMMUNOLOGY
IF27.6
err2022-12-21
err110
errOAAI
errVignali, Paolo D. A.; DePeaux, Kristin; Watson, McLane J. J.; Ye, Chenxian; Ford, B. Rhodes; Lontos, Konstantinos; McGaa, Nicole K. K.; Scharping, Nicole E. E.; Menk, Ashley V. V.; Robson, Simon C. C.; Poholek, Amanda C. C.; Rivadeneira, Dayana B. B.; Delgoffe, Greg M. M.
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Tumor microenvironmental signals reshape chromatin landscapes to limit the functional potential of exhausted T cells
errSCIENCE IMMUNOLOGY
IF16.3
err2022-08-26
err50
errOAAI
errFord, B. Rhodes; Vignali, Paolo D. A.; Rittenhouse, Natalie L.; Scharping, Nicole E.; Peralta, Ronal; Lontos, Konstantinos; Frisch, Andrew T.; Delgoffe, Greg M.; Poholek, Amanda C.
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IL-33 acts as a costimulatory signal to generate alloreactive Th1 cells in graft-versus-host disease
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2022-06-15
err11
errOAAI
errDwyer, Gaelen K.; Mathews, Lisa R.; Villegas, Jose A.; Lucas, Anna; de Peredo, Anne Gonzalez; Blazar, Bruce R.; Girard, Jean-Philippe; Poholek, Amanda C.; Luther, Sanjiv A.; Shlomchik, Warren; Turnquist, Heth R.
err分享
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研究方向

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合作学者
合作期刊
R
Richard A. Flavell
H 指数: 246 · 论文数: 1.5K
B
Bruce R. Blazar
H 指数: 148 · 论文数: 1.5K
S
Simon C. Watkins
H 指数: 147 · 论文数: 1.1K
D
Daniel C. Douek
H 指数: 137 · 论文数: 596
A
Alan Sher
H 指数: 133 · 论文数: 555
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