Henry A. Lester - Publications, H-index & Citations

Henry A. Lester

california institute of technology

98H指数

470论文数

3.2W被引数

收录论文 169

发表时间

Targeted Mutations Activate Allosteric Modulation of α5-Containing Nicotinic Acetylcholine Receptors 靶向突变激活α5-含烟碱乙酰胆碱受体的别构调节

ACS Chemical Neuroscience

IF3.9

2026-06-04

OAAI

Christopher B. Marotta; Henry A. Lester; Dennis A. Dougherty

Hydrogel Encapsulation of a Designed Fluorescent Protein Biosensor for Continuous Measurements of Sub-100 nM Nicotine

ACS APPLIED BIO MATERIALS

IF4.7

2025-12-01

PREAI

Nichols, Aaron L.; Marotta, Christopher B.; Frisenhahn, Nicholas J.; Dalfonzo, Sophia R.; Muthusamy, Anand; Wagenaar, Daniel A.; Mayo, Stephen L.; Dougherty, Dennis A.; Lester, Henry A.

Continuous Nicotine Monitors for Personal Nicotine Pharmacokinetics: A Receptor-Aware Research Agenda 连续性尼古丁监测仪用于个人尼古丁药代动力学：一项受体感知的研究议程

NICOTINE & TOBACCO RESEARCH

IF3

2025-03-13

PREAI

Aaron L Nichols; Christopher B Marotta; Heather Lukas; Nicholas J Friesenhahn; Daniel A Wagenaar; Stephen L Mayo; Dennis A Dougherty; Neal L Benowitz; Wei Gao; Anand K Muthusamy; Henry A Lester

Simulating early steps in nicotine dependence: Pharmacokinetics, activation, and chaperoning of nicotinic receptors 模拟尼古丁依赖的早期步骤：尼古丁受体的药代动力学、激活和分子伴侣作用

MOLECULAR PHARMACOLOGY

IF3

2025-01-01

PREAI

Wang, Alexander Z.; Jeon, Janice; Drenan, Ryan M.; Lester, Henry A.

Antidepressants enter cells, organelles, and membranes 抗抑郁药进入细胞、细胞器和细胞膜

NEUROPSYCHOPHARMACOLOGY

IF7.1

2023-10-02

OAAI

Blumenfeld, Zack; Bera, Kallol; Castren, Eero; Lester, Henry A.

Human α6β4 Nicotinic Acetylcholine Receptor: Heterologous Expression and Agonist Behavior Provide Insights into the Immediate Binding Site

MOLECULAR PHARMACOLOGY

IF3

2023-06-01

PREAI

Maldifassi, Maria Constanza; Campello, Hugo Rego; Gallagher, Timothy; Lester, Henry A.; Dougherty, Dennis A.

Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands (vol 11, e74648, 2022)

ELIFE

IF0

2022-12-15

OAAI

Nichols, Aaron L.; Blumenfeld, Zack; Fan, Chengcheng; Luebbert, Laura; Blom, Annet E. M.; Cohen, Bruce N.; Marvin, Jonathan S.; Borden, Philip M.; Kim, Charlene H.; Muthusamy, Anand K.; Shivange, Amol V.; Knox, Hailey J.; Campello, Hugo Rego; Wang, Jonathan H.; Dougherty, Dennis A.; Looger, Loren L.; Gallagher, Timothy; Rees, Douglas C.; Lester, Henry A.

How many SARS-CoV-2 viroporins are really ion channels?

COMMUNICATIONS BIOLOGY

IF5.1

2022-08-25

OAAI

Harrison, Neil L.; Abbott, Geoffrey W.; Gentzsch, Martina; Aleksandrov, Andrei; Moroni, Anna; Thiel, Gerhard; Grant, Stephen; Nichols, Colin G.; Lester, Henry A.; Hartel, Andreas; Shepard, Kenneth; Garcia, David Cabrera; Yazawa, Masayuki

Characterization of Binding Site Interactions and Selectivity Principles in the α3β4 Nicotinic Acetylcholine Receptor

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2022-08-25

PREAI

Knox, Hailey J.; Campello, Hugo Rego; Lester, Henry A.; Gallagher, Timothy; Dougherty, Dennis A.

Three Mutations Convert the Selectivity of a Protein Sensor from Nicotinic Agonists to S-Methadone for Use in Cells, Organelles, and Biofluids

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2022-04-21

OAAI

Muthusamy, Anand K.; Kim, Charlene H.; Virgil, Scott C.; Knox, Hailey J.; Marvin, Jonathan S.; Nichols, Aaron L.; Cohen, Bruce N.; Dougherty, Dennis A.; Looger, Loren L.; Lester, Henry A.

Regulation of epithelial sodium channel activity by SARS-CoV-1 and SARS-CoV-2 proteins

BIOPHYSICAL JOURNAL

IF3.1

2021-07-01

OAAI

Grant, Stephen N.; Lester, Henry A.

Proteins for increased surface expression of the α6β4 nicotinic acetylcholine receptor: nothing but good news?

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2020-10-19

OAAI

Grant, Stephen; Lester, Henry A.

Biosensors Show the Pharmacokinetics of S-Ketamine in the Endoplasmic Reticulum

FRONTIERS IN CELLULAR NEUROSCIENCE

IF4

2019-11-12

OAAI

Bera, Kallol; Kamajaya, Aron; Shivange, Amol, V; Muthusamy, Anand K.; Nichols, Aaron L.; Borden, Philip M.; Grant, Stephen; Jeon, Janice; Lin, Elaine; Bishara, Ishak; Chin, Theodore M.; Cohen, Bruce N.; Kim, Charlene H.; Unger, Elizabeth K.; Tian, Lin; Marvin, Jonathan S.; Looger, Loren L.; Lester, Henry A.

Nicotine Bound to Its Receptors: New Structures for a Vexing Pathopharmacological Problem

NEURON

IF15

2019-11-01

OAAI

Lester, Henry A.; Dougherty, Dennis A.

Brain Region-Specific nAChR and Associated Protein Abundance Alterations Following Chronic Nicotine and/or Menthol Exposure 慢性尼古丁和/或薄荷醇暴露后大脑区域特异性nAChR和相关蛋白质丰度变化

JOURNAL OF PROTEOME RESEARCH

IF3.6

2019-10-28

OAAI

Mulcahy, Matthew J.; Huard, Stephanie M.; Paulo, Joao A.; Wang, Jonathan H.; McKinney, Sheri; Henderson, Brandon J.; Lester, Henry A.

Probing Binding Interactions of Cytisine Derivatives to the α4β2 Nicotinic Acetylcholine Receptor

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2019-09-13

OAAI

Blom, Annet E. M.; Campello, Hugo Rego; Lester, Henry A.; Gallagher, Timothy; Dougherty, Dennis A.

Chronic Menthol Does Not Change Stoichiometry or Functional Plasma Membrane Levels of Mouse α3β4-Containing Nicotinic Acetylcholine Receptors

MOLECULAR PHARMACOLOGY

IF3

2019-04-01

OAAI

Bavan, Selvan; Kim, Charlene H.; Henderson, Brandon J.; Lester, Henry A.

Determining the pharmacokinetics of nicotinic drugs in the endoplasmic reticulum using biosensors

JOURNAL OF GENERAL PHYSIOLOGY

IF2.9

2019-02-04

OAAI

Shiyange, Amol, V; Borden, Philip M.; Muthusamy, Anand K.; Nichols, Aaron L.; Bera, Kailo; Bao, Huan; Bishara, Ishak; Jeon, Janice; Mulcahy, Matthew J.; Cohen, Bruce; O'Riordan, Saidhbhe L.; Kim, Charlene; Dougherty, Dennis A.; Chapman, Edwin R.; Marvin, Jonathan S.; Looger, Loren L.; Lester, Henry A.

Chronic nicotine improves cognitive and social impairment in mice overexpressing wild type α-synuclein

NEUROBIOLOGY OF DISEASE

IF5.6

2018-09-01

OAAI

Subramaniam, Sudhakar R.; Magen, Iddo; Bove, Nicholas; Zhu, Chunni; Lemesre, Vincent; Dutta, Garima; Elias, Chris Jean; Lester, Henry A.; Chesselet, Marie-Francoise

α1-FANGs: Protein Ligands Selective for the α-Bungarotoxin Site of the α1-Nicotinic Acetylcholine Receptor

ACS CHEMICAL BIOLOGY

IF3.8

2018-07-30

OAAI

Nichols, Aaron L.; Noridomi, Kaori; Hughes, Christopher R.; Jalali-Yazdi, Farzad; Eaton, J. Brek; Lan Huong Lai; Advani, Gaurav; Lukas, Ronald J.; Lester, Henry A.; Chen, Lin; Roberts, Richard W.

研究方向