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S

Sangsu Bae

seoul national university

39H指数
185论文数
1.1W被引数
收录论文 87
发表时间
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Highly efficient base editing at PCSK9 and normal human embryo development在PCSK9和正常人类胚胎发育中的高效碱基编辑
errNature
IF48.5
err2026-09-09
err0
PREAI
errStepan Jerabek; Chanju Jung; Michelle Kappy; Qiaojin Zhao; Julie Sung; Ning Wang; Euihyun Kim; Jimin Kim; Marcos Iuri Roos Kulmann; Madeleine Bliss King; Mitchell John McAndrew; Meng Li; Sakshi Bhatele; Melisa Isado; Hong-Su Jang; Michal Dolezal; Robert Prosser; Shuangyi Xu; Gue-Ho Hwang; Iva Pichova; Jia Xu; Diego Marin; Jae-Sung Woo; Sangsu Bae; Nathan Treff; Audrone Lapinaite; Dieter Egli
err分享
err收藏
Optimized Cas9-Enriched Nanopore Sequencing and Analysis Workflow for Clinical Diagnosis of Repeat Expansion Disorders优化Cas9富集纳米孔测序及分析流程，用于临床诊断重复扩展疾病
errAdvanced Science
IF14.1
err2026-08-29
err0
errOAAI
errSeungbok Lee; Chanju Jung; Minjeong Kim; Narae Kim; Gue-Ho Hwang; Soon-Tae Lee; Kon Chu; Sang Kun Lee; Han-Joon Kim; Jong-Hee Chae; Sangsu Bae; Jangsup Moon
err分享
err收藏
Engineered ADARs enable precision A-to-G base editing of DNA工程化ADARs实现DNA中A到G的碱基精确编辑
errNature Biotechnology
IF41.7
err2026-07-10
err0
errOAAI
errHyeon Woo Im; Bada Jeong; Yeji Lee; Ye Eun Oh; Chanju Jung; Yong-Woo Kim; Doyoon Kim; Soyoon Lee; Heesoo Uhm; Yohan Kim; Sangsu Bae
err分享
err收藏
Evolution of Prime Editing: Enhancing Efficiency and Expanding CapacityPrime Editing的演化：提升效率与拓展能力
errAdvanced Science
IF14.1
err2026-02-11
err0
errOAAI
errJihyeon Yu; Ju-Chan Park; Heesoo Uhm; Yong-Woo Kim; Hyeon Woo Im; Sangsu Bae
err分享
err收藏
Neuronal mitochondrial disaggregase CLPB ameliorates Huntington's disease pathology in mice神经元线粒体解聚酶CLPB改善了小鼠亨廷顿病病理学
errTheranostics
IF13.3
err2026-01-01
err1
PREAI
errKim, Hyeonho; Hyun, Gaeun; Kim, Seunghye; Yu, Changmo; Hong, Young-gi; Yu, Jihyeon; Bae, Sangsu; Rhee, Hyun-Woo; Ko, Jaewon; Um, Ji Won
err分享
err收藏
Expansion of artificial intelligence for genome editing人工智能在基因组编辑领域的拓展
errNature Structural & Molecular Biology
IF10.1
err2025-11-20
err0
PREAI
errHeesoo Uhm; Sangsu Bae
err分享
err收藏
Prime Editing of ATRX point mutations in glioblastoma reveals lethal dependencies and targetable vulnerabilitiesATRX基因点突变的体细胞编辑揭示了致命依赖性及可靶向的脆弱性
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errKim, Kanggeon; Lee, Yeji; Outwin, Emily; Humphrey, Timothy; Bae, Sangsu
err分享
err收藏
PAM-flexible adenine base editing rescues hearing loss in a humanized MPZL2 mouse model harboring an East Asian founder mutationPAM-flexible腺嘌呤碱基编辑技术挽救了携带东亚始祖突变的人源化MPZL2小鼠模型的听力损失
errNature Communications
IF15.7
err2025-08-05
err0
errOAAI
errShao Wei Hu; Sohyang Jeong; Luoying Jiang; Hansol Koo; Zijing Wang; Won Hoon Choi; Biyun Zhu; Heeyoung Seok; Yi Zhou; Min Gu Kim; Dan Mu; Huixia Guo; Ziyi Zhou; Sung Ho Jung; Yingting Zhang; Ho Byung Chae; Liheng Chen; Sung-Yeon Lee; Luo Guo; Myung-Whan Suh; Yang Xiao; Moo Kyun Park; Honghai Tang; Jae-Jin Song; Xi Chen; Ai Chen; Jun Ho Lee; Sangsu Bae; Sang-Yeon Lee; Yilai Shu
err分享
err收藏
AI-generated MLH1 small binder improves prime editing efficiencyAI生成的MLH1小结合物可提高基础编辑效率
errCell
IF42.5
err2025-08-05
err0
errOAAI
errJu-Chan Park; Heesoo Uhm; Yong-Woo Kim; Ye Eun Oh; Jang Hyeon Lee; Jiyun Yang; Kyoungmi Kim; Sangsu Bae
err分享
err收藏
A rational engineering strategy for structural dynamics modulation enables target specificity enhancement of the Cas9 nuclease一种针对结构动力学调控的理性工程策略能够增强Cas9核酸酶的目标特异性。
errNUCLEIC ACIDS RESEARCH
IF13.1
err2025-07-08
err1
errOAAI
errSung, Keewon; Jung, Youngri; Kim, Nahye; Kim, Yong-Woo; Kim, Hyongbum Henry; Kim, Seong Keun; Bae, Sangsu
err分享
err收藏
Bystander editing by adenine base editors impairs vision restoration in a mouse model of Leber congenital amaurosis腺嘌呤碱基编辑器介导的旁观者编辑损害了Leber先天性黑蒙症小鼠模型中的视力恢复
errMOLECULAR THERAPY METHODS & CLINICAL DEVELOPMENT
IF4.7
err2025-06-01
err0
errOAAI
errSeok-Hoon Lee; Jun Wu; Dongjoon Im; Gue-ho Hwang; You Kyeong Jeong; Hui Jiang; Seok Jae Lee; Dong Hyun Jo; William A. Goddard; Jeong Hun Kim; Sangsu Bae
err分享
err收藏
Cellular dsRNA interactome captured by K1 antibody reveals the regulatory map of exogenous RNA sensing
errCOMMUNICATIONS BIOLOGY
IF5.1
err2025-03-07
err0
errOAAI
errLim, Jina; Lee, Namseok; Ju, Seonmin; Kim, Jeesoo; Mun, Subin; Jeon, Moonhyeon; Lee, Yong-ki; Lee, Seok-Hoon; Ku, Jayoung; Kim, Sujin; Bae, Sangsu; Kim, Jong-Seo; Kim, Yoosik
err分享
err收藏
Large DNA deletions occur during DNA repair at 20-fold lower frequency for base editors and prime editors than for Cas9 nucleases
errNATURE BIOMEDICAL ENGINEERING
IF26.6
err2024-11-04
err0
errOAAI
errHwang, Gue-Ho; Lee, Seok-Hoon; Oh, Minsik; Kim, Segi; Habib, Omer; Jang, Hyeon-Ki; Kim, Heon Seok; Kim, Youngkuk; Kim, Chan Hyuk; Kim, Sun; Bae, Sangsu
err分享
err收藏
Tumor-intrinsic role of ICAM-1 in driving metastatic progression of triple-negative breast cancer through direct interaction with EGFRICAM-1通过与EGFR直接相互作用在驱动三阴性乳腺癌转移进展中的肿瘤内在作用
errMOLECULAR CANCER
IF33.9
err2024-10-16
err1
errOAAI
errKang, Jae-Hyeok; Uddin, Nizam; Kim, Seungmo; Zhao, Yi; Yoo, Ki-Chun; Kim, Min-Jung; Hong, Sung-Ah; Bae, Sangsu; Lee, Jeong-Yeon; Shin, Incheol; Jin, Young Woo; O'Hagan, Heather M.; Yi, Joo Mi; Lee, Su-Jae
err分享
err收藏
Revertant Mosaic Skin Punch Grafting in Recessive Dystrophic Epidermolysis Bullosa
errJAMA DERMATOLOGY
IF11
err2024-10-01
err0
PREAI
errSong, Ahreum; Hwang, Gue-Ho; Kim, Song-Ee; Roh, Mi Ryung; Hong, Sung-Ah; Bae, Sangsu; Lee, Sang Eun
err分享
err收藏
Discovery of novel disease-causing mutation in SSBP1 and its correction using adenine base editor to improve mitochondrial function
errMOLECULAR THERAPY NUCLEIC ACIDS
IF6.1
err2024-09-01
err0
errOAAI
errCha, Ju Hyuen; Lee, Seok-Hoon; Yun, Yejin; Choi, Won Hoon; Koo, Hansol; Jung, Sung Ho; Chae, Ho Byung; Lee, Dae Hee; Lee, Seok Jae; Jo, Dong Hyun; Kim, Jeong Hun; Song, Jae-Jin; Chae, Jong-Hee; Lee, Jun Ho; Park, Jiho; Kang, Jin Young; Bae, Sangsu; Lee, Sang-Yeon
err分享
err收藏
Prion-like domain mediated phase separation of ARID1A promotes oncogenic potential of Ewing's sarcoma
errNATURE COMMUNICATIONS
IF15.7
err2024-08-03
err3
errOAAI
errKim, Yong Ryoul; Joo, Jaegeon; Lee, Hee Jung; Kim, Chaelim; Park, Ju-Chan; Yu, Young Suk; Kim, Chang Rok; Lee, Do Hui; Cha, Joowon; Kwon, Hyemin; Hanssen, Kimberley M.; Grunewald, Thomas G. P.; Choi, Murim; Han, Ilkyu; Bae, Sangsu; Jung, Inkyung; Shin, Yongdae; Baek, Sung Hee
err分享
err收藏
Enhancing genome editing in hPSCs through dual inhibition of DNA damage response and repair pathways (vol 15, 4002 , 2024)
errNATURE COMMUNICATIONS
IF15.7
err2024-07-29
err0
errOAAI
errPark, Ju-Chan; Kim, Yun-Jeong; Hwang, Gue-Ho; Kang, Chan Young; Bae, Sangsu; Cha, Hyuk-Jin
err分享
err收藏
Enhancing genome editing in hPSCs through dual inhibition of DNA damage response and repair pathways
errNATURE COMMUNICATIONS
IF15.7
err2024-05-11
err2
errOAAI
errPark, Ju-Chan; Kim, Yun-Jeong; Hwang, Gue-Ho; Kang, Chan Young; Bae, Sangsu; Cha, Hyuk-Jin
err分享
err收藏
NFAT1 and NFκB regulates expression of the common γ-chain cytokine receptor in activated T cells
errCELL COMMUNICATION AND SIGNALING
IF8.9
err2023-10-30
err1
errOAAI
errShim, Ju A.; Lee, So Min; Jeong, Jin Woo; Kim, Hyori; Son, Woo Jae; Park, Jun Hong; Song, Parkyong; Im, Sin-Hyeog; Bae, Sangsu; Park, Jung-Hyun; Jo, Yuna; Hong, Changwan
err分享
err收藏

研究方向

暂时未获取到该数据
合作学者
合作期刊
W
William A. Goddard
H 指数: 184 · 论文数: 2.4K
J
Jonathan D. G. Jones
H 指数: 138 · 论文数: 658
Y
Young Ho Kim
H 指数: 89 · 论文数: 2.8K
J
Jin‐Soo Kim
H 指数: 89 · 论文数: 614
D
Doreen Ware
H 指数: 83 · 论文数: 252
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